Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Rhomboid protease GlpG (Escherichia coli (Enterobacteria)) | BDBM50199883 (3,4‐Dichloroisocoumarin (2) | 3,4-Dichloro-i...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 1.90E+4 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Technische Universität München | Assay Description We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP. | ACS Chem Biol 10: 2325-33 (2015) Article DOI: 10.1021/acschembio.5b00514 BindingDB Entry DOI: 10.7270/Q2668BZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rhomboid protease GlpG (Escherichia coli (Enterobacteria)) | BDBM165197 ((4S)‐3‐butyl‐4‐(pent‐...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.40E+4 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Technische Universität München | Assay Description We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP. | ACS Chem Biol 10: 2325-33 (2015) Article DOI: 10.1021/acschembio.5b00514 BindingDB Entry DOI: 10.7270/Q2668BZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rhomboid protease GlpG (Escherichia coli (Enterobacteria)) | BDBM50572957 (CHEMBL4871112) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of GlpG in Escherichia coli BL21 assessed as inhibition of FP-Rh labeling treated with compound for 30 mins prior to FP-Rh addition by com... | Citation and Details Article DOI: 10.1016/j.bmcl.2021.128290 BindingDB Entry DOI: 10.7270/Q2FR01D1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rhomboid protease GlpG (Escherichia coli (Enterobacteria)) | BDBM50572958 (CHEMBL4856971) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of GlpG in Escherichia coli BL21 assessed as inhibition of FP-Rh labeling treated with compound for 30 mins prior to FP-Rh addition by com... | Citation and Details Article DOI: 10.1016/j.bmcl.2021.128290 BindingDB Entry DOI: 10.7270/Q2FR01D1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rhomboid protease GlpG (Escherichia coli (Enterobacteria)) | BDBM50572959 (CHEMBL4854450) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.10E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of GlpG in Escherichia coli BL21 assessed as inhibition of FP-Rh labeling treated with compound for 30 mins prior to FP-Rh addition by com... | Citation and Details Article DOI: 10.1016/j.bmcl.2021.128290 BindingDB Entry DOI: 10.7270/Q2FR01D1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rhomboid protease GlpG (Escherichia coli (Enterobacteria)) | BDBM50572960 (CHEMBL4859980) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of GlpG in Escherichia coli BL21 assessed as inhibition of FP-Rh labeling treated with compound for 30 mins prior to FP-Rh addition by com... | Citation and Details Article DOI: 10.1016/j.bmcl.2021.128290 BindingDB Entry DOI: 10.7270/Q2FR01D1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rhomboid protease GlpG (Escherichia coli (Enterobacteria)) | BDBM50572955 (CHEMBL4861272) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of GlpG in Escherichia coli BL21 assessed as inhibition of FP-Rh labeling treated with compound for 30 mins prior to FP-Rh addition by com... | Citation and Details Article DOI: 10.1016/j.bmcl.2021.128290 BindingDB Entry DOI: 10.7270/Q2FR01D1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rhomboid protease GlpG (Escherichia coli (Enterobacteria)) | BDBM50572956 (CHEMBL4855230) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of GlpG in Escherichia coli BL21 assessed as inhibition of FP-Rh labeling treated with compound for 30 mins prior to FP-Rh addition by com... | Citation and Details Article DOI: 10.1016/j.bmcl.2021.128290 BindingDB Entry DOI: 10.7270/Q2FR01D1 | |||||||||||
More data for this Ligand-Target Pair |