Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM24773![]() (AMG 706 | AMG-706 | Motesanib | N-(3,3-dimethyl-1,...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase MMDB PC cid PC sid PDB UniChem Patents | Article PCBioAssay | n/a | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) Article DOI: 10.1124/jpet.105.083436 BindingDB Entry DOI: 10.7270/Q2Q52N0G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM31085![]() (1-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluorom...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem | Article PCBioAssay | n/a | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) Article DOI: 10.1124/jpet.105.083436 BindingDB Entry DOI: 10.7270/Q2Q52N0G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM26300![]() (2-{3-[(7-{3-[ethyl(2-hydroxyethyl)amino]propoxy}qu...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents | Article PCBioAssay | n/a | n/a | n/a | 5.70E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) Article DOI: 10.1124/jpet.105.083436 BindingDB Entry DOI: 10.7270/Q2Q52N0G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM13533![]() (1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents | Article PCBioAssay | n/a | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) Article DOI: 10.1124/jpet.105.083436 BindingDB Entry DOI: 10.7270/Q2Q52N0G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM25118![]() ((3Z)-4-amino-5-fluoro-3-[5-(4-methylpiperazino)-1,...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Patents | Article PCBioAssay | n/a | n/a | n/a | 8.20E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) Article DOI: 10.1124/jpet.105.083436 BindingDB Entry DOI: 10.7270/Q2Q52N0G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM31088![]() (1-methyl-5-[2-[5-(trifluoromethyl)-1H-imidazol-2-y...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase PC cid PC sid PDB UniChem Patents | Article PCBioAssay | n/a | n/a | n/a | 87 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) Article DOI: 10.1124/jpet.105.083436 BindingDB Entry DOI: 10.7270/Q2Q52N0G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM4779![]() (CHEMBL31965 | CHEMBL545315 | CI-1033 | Canertinib ...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents | Article PCBioAssay | n/a | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) Article DOI: 10.1124/jpet.105.083436 BindingDB Entry DOI: 10.7270/Q2Q52N0G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM31090![]() ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase PC cid PC sid PDB UniChem Patents | Article PCBioAssay | n/a | n/a | n/a | 310 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) Article DOI: 10.1124/jpet.105.083436 BindingDB Entry DOI: 10.7270/Q2Q52N0G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM5446![]() (CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents | Article PCBioAssay | n/a | n/a | n/a | 680 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) Article DOI: 10.1124/jpet.105.083436 BindingDB Entry DOI: 10.7270/Q2Q52N0G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM31099![]() (2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S)-3-hydroxy...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid PDB UniChem Patents | Article PCBioAssay | n/a | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) Article DOI: 10.1124/jpet.105.083436 BindingDB Entry DOI: 10.7270/Q2Q52N0G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM5447![]() (CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents | Article PCBioAssay | n/a | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) Article DOI: 10.1124/jpet.105.083436 BindingDB Entry DOI: 10.7270/Q2Q52N0G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM17055![]() ((18S)-18-[(dimethylamino)methyl]-17-oxa-4,14,21-tr...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase MMDB PC cid PC sid PDB UniChem Patents | Article PCBioAssay | n/a | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) Article DOI: 10.1124/jpet.105.083436 BindingDB Entry DOI: 10.7270/Q2Q52N0G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM4851![]() ((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents | Article PCBioAssay | n/a | n/a | n/a | 8.80E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) Article DOI: 10.1124/jpet.105.083436 BindingDB Entry DOI: 10.7270/Q2Q52N0G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM13531![]() (4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridy...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem | Article PCBioAssay | n/a | n/a | n/a | 510 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) Article DOI: 10.1124/jpet.105.083436 BindingDB Entry DOI: 10.7270/Q2Q52N0G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM13336![]() (4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents | Article PCBioAssay | n/a | n/a | n/a | 420 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) Article DOI: 10.1124/jpet.105.083436 BindingDB Entry DOI: 10.7270/Q2Q52N0G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM31095![]() (5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Patents | Article PCBioAssay | n/a | n/a | n/a | 94 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) Article DOI: 10.1124/jpet.105.083436 BindingDB Entry DOI: 10.7270/Q2Q52N0G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM16673![]() (4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents | Article PCBioAssay | n/a | n/a | n/a | 6.20E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) Article DOI: 10.1124/jpet.105.083436 BindingDB Entry DOI: 10.7270/Q2Q52N0G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM31096![]() (CHEMBL290084 | Staurosporine | cid_451705) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Patents | Article PCBioAssay | n/a | n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) Article DOI: 10.1124/jpet.105.083436 BindingDB Entry DOI: 10.7270/Q2Q52N0G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM4814![]() (CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents | Article PCBioAssay | n/a | n/a | n/a | 3.90E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) Article DOI: 10.1124/jpet.105.083436 BindingDB Entry DOI: 10.7270/Q2Q52N0G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM21![]() (6-[(4R,5S,6S,7R)-4,7-dibenzyl-3-(5-carboxypentyl)-...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem | Article PCBioAssay | n/a | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) Article DOI: 10.1124/jpet.105.083436 BindingDB Entry DOI: 10.7270/Q2Q52N0G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM50308060![]() (16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,1...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | n/a | 85 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by ChEMBL | Assay Description Binding affinity to CIT | Blood 114: 2984-92 (2009) Article DOI: 10.1182/blood-2009-05-222034 BindingDB Entry DOI: 10.7270/Q2PN95V2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM50326053![]() (CHEMBL608533 | PKC-412) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by ChEMBL | Assay Description Binding affinity to CIT | Blood 114: 2984-92 (2009) Article DOI: 10.1182/blood-2009-05-222034 BindingDB Entry DOI: 10.7270/Q2PN95V2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM2579![]() ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by ChEMBL | Assay Description Binding constant for CIT kinase domain | Nat Biotechnol 29: 1046-51 (2011) Article DOI: 10.1038/nbt.1990 BindingDB Entry DOI: 10.7270/Q25D8S70 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM50308060![]() (16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,1...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | n/a | 85 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by ChEMBL | Assay Description Binding constant for CIT kinase domain | Nat Biotechnol 29: 1046-51 (2011) Article DOI: 10.1038/nbt.1990 BindingDB Entry DOI: 10.7270/Q25D8S70 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM50326053![]() (CHEMBL608533 | PKC-412) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by ChEMBL | Assay Description Binding constant for CIT kinase domain | Nat Biotechnol 29: 1046-51 (2011) Article DOI: 10.1038/nbt.1990 BindingDB Entry DOI: 10.7270/Q25D8S70 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM50026612![]() (BIBF-1120 | NINTEDANIB | Nintedanib | Vargatef) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by ChEMBL | Assay Description Binding constant for CIT kinase domain | Nat Biotechnol 29: 1046-51 (2011) Article DOI: 10.1038/nbt.1990 BindingDB Entry DOI: 10.7270/Q25D8S70 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM2579![]() ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by ChEMBL | Assay Description Binding constant for CIT kinase domain | Nat Biotechnol 26: 127-32 (2008) Article DOI: 10.1038/nbt1358 BindingDB Entry DOI: 10.7270/Q2TT4RX2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM50326053![]() (CHEMBL608533 | PKC-412) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | n/a | >1 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by ChEMBL | Assay Description Binding constant for CIT kinase domain | Nat Biotechnol 26: 127-32 (2008) Article DOI: 10.1038/nbt1358 BindingDB Entry DOI: 10.7270/Q2TT4RX2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM50300690![]() (CHEMBL576982 | N-(5-tert-Butyl-isoxazol-3-yl)-N'-{...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by ChEMBL | Assay Description Binding affinity to CIT | Blood 114: 2984-92 (2009) Article DOI: 10.1182/blood-2009-05-222034 BindingDB Entry DOI: 10.7270/Q2PN95V2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM50326054![]() (CHEMBL1240703) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by ChEMBL | Assay Description Binding affinity to CIT | Blood 114: 2984-92 (2009) Article DOI: 10.1182/blood-2009-05-222034 BindingDB Entry DOI: 10.7270/Q2PN95V2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM13535![]() (4-[6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by ChEMBL | Assay Description Binding affinity to CIT | Blood 114: 2984-92 (2009) Article DOI: 10.1182/blood-2009-05-222034 BindingDB Entry DOI: 10.7270/Q2PN95V2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM4814![]() (CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | n/a | 3.90E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by ChEMBL | Assay Description Binding affinity to CIT | Blood 114: 2984-92 (2009) Article DOI: 10.1182/blood-2009-05-222034 BindingDB Entry DOI: 10.7270/Q2PN95V2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM16673![]() (4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | n/a | 6.20E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by ChEMBL | Assay Description Binding affinity to CIT | Blood 114: 2984-92 (2009) Article DOI: 10.1182/blood-2009-05-222034 BindingDB Entry DOI: 10.7270/Q2PN95V2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM25045![]() (3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by ChEMBL | Assay Description Binding constant for CIT kinase domain | Nat Biotechnol 29: 1046-51 (2011) Article DOI: 10.1038/nbt.1990 BindingDB Entry DOI: 10.7270/Q25D8S70 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM31095![]() (5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | n/a | 94 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by ChEMBL | Assay Description Binding constant for CIT kinase domain | Nat Biotechnol 29: 1046-51 (2011) Article DOI: 10.1038/nbt.1990 BindingDB Entry DOI: 10.7270/Q25D8S70 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM60665![]() (BDBM50249542 | US9145414, R406 | US9212178, R406) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase DrugBank PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | 440 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by ChEMBL | Assay Description Binding constant for CIT kinase domain | Nat Biotechnol 29: 1046-51 (2011) Article DOI: 10.1038/nbt.1990 BindingDB Entry DOI: 10.7270/Q25D8S70 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM50332294![]() (CHEMBL1287853 | N-tert-butyl-3-(5-methyl-2-(4-(2-(...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by ChEMBL | Assay Description Binding constant for CIT kinase domain | Nat Biotechnol 29: 1046-51 (2011) Article DOI: 10.1038/nbt.1990 BindingDB Entry DOI: 10.7270/Q25D8S70 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM5446![]() (CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | n/a | 680 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by ChEMBL | Assay Description Binding constant for CIT kinase domain | Nat Biotechnol 29: 1046-51 (2011) Article DOI: 10.1038/nbt.1990 BindingDB Entry DOI: 10.7270/Q25D8S70 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM6568![]() (6-(2,6-dichlorophenyl)-8-methyl-2-{[3-(methylsulfa...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by ChEMBL | Assay Description Binding constant for CIT kinase domain | Nat Biotechnol 29: 1046-51 (2011) Article DOI: 10.1038/nbt.1990 BindingDB Entry DOI: 10.7270/Q25D8S70 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM50306682![]() ((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by ChEMBL | Assay Description Binding constant for CIT kinase domain | Nat Biotechnol 29: 1046-51 (2011) Article DOI: 10.1038/nbt.1990 BindingDB Entry DOI: 10.7270/Q25D8S70 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM24773![]() (AMG 706 | AMG-706 | Motesanib | N-(3,3-dimethyl-1,...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by ChEMBL | Assay Description Binding constant for CIT kinase domain | Nat Biotechnol 29: 1046-51 (2011) Article DOI: 10.1038/nbt.1990 BindingDB Entry DOI: 10.7270/Q25D8S70 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM13530![]() (4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by ChEMBL | Assay Description Binding constant for CIT kinase domain | Nat Biotechnol 29: 1046-51 (2011) Article DOI: 10.1038/nbt.1990 BindingDB Entry DOI: 10.7270/Q25D8S70 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM50193995![]() (3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by ChEMBL | Assay Description Binding constant for CIT kinase domain | Nat Biotechnol 29: 1046-51 (2011) Article DOI: 10.1038/nbt.1990 BindingDB Entry DOI: 10.7270/Q25D8S70 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM50237710![]() (4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifl...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by ChEMBL | Assay Description Binding constant for CIT kinase domain | Nat Biotechnol 29: 1046-51 (2011) Article DOI: 10.1038/nbt.1990 BindingDB Entry DOI: 10.7270/Q25D8S70 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM50355495![]() (CHEMBL1908391) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by ChEMBL | Assay Description Binding constant for CIT kinase domain | Nat Biotechnol 29: 1046-51 (2011) Article DOI: 10.1038/nbt.1990 BindingDB Entry DOI: 10.7270/Q25D8S70 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM25028![]() (4-[2-(1H-indazol-4-yl)-6-[(4-methanesulfonylpipera...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by ChEMBL | Assay Description Binding constant for CIT kinase domain | Nat Biotechnol 29: 1046-51 (2011) Article DOI: 10.1038/nbt.1990 BindingDB Entry DOI: 10.7270/Q25D8S70 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM25919![]() (BMS-345541 | BMS345541 | CHEMBL471496 | N-(2-amino...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by ChEMBL | Assay Description Binding constant for CIT kinase domain | Nat Biotechnol 29: 1046-51 (2011) Article DOI: 10.1038/nbt.1990 BindingDB Entry DOI: 10.7270/Q25D8S70 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM31085![]() (1-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluorom...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by ChEMBL | Assay Description Binding constant for CIT kinase domain | Nat Biotechnol 29: 1046-51 (2011) Article DOI: 10.1038/nbt.1990 BindingDB Entry DOI: 10.7270/Q25D8S70 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM31093![]() (4-[[7-[2,6-bis(fluoranyl)phenyl]-9-chloranyl-5H-py...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by ChEMBL | Assay Description Binding constant for CIT kinase domain | Nat Biotechnol 29: 1046-51 (2011) Article DOI: 10.1038/nbt.1990 BindingDB Entry DOI: 10.7270/Q25D8S70 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Citron Rho-interacting kinase (Homo sapiens (Human)) | BDBM60589![]() (6-{[6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase DrugBank PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by ChEMBL | Assay Description Binding constant for CIT kinase domain | Nat Biotechnol 29: 1046-51 (2011) Article DOI: 10.1038/nbt.1990 BindingDB Entry DOI: 10.7270/Q25D8S70 | |||||||||||
More data for this Ligand-Target Pair |
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