BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cysteine protease SpeB (SpeB)'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cysteine protease SpeB (SpeB)


(Streptococcus pyogenes (Firmicutes))
BDBM152724
PNG
(2477)
Show SMILES O=C(NCC#N)OCc1ccccc1
Show InChI InChI=1S/C10H10N2O2/c11-6-7-12-10(13)14-8-9-4-2-1-3-5-9/h1-5H,7-8H2,(H,12,13)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
PDB
UniChem
PDB
Article
PubMed
8.00E+3n/a 1.40E+4n/an/an/an/a7.4n/a



The Scripps Research Institute



Assay Description
SpeB was incubated at 50 nM in the presence of increasing amounts of inhibitor (3 μM to 200 μM) in a reaction buffer consisting of PBS at p...


Biochemistry 54: 4365-73 (2015)


Article DOI: 10.1021/acs.biochem.5b00607
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)