Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
GTPase HRas (Homo sapiens (Human)) | BDBM50089960![]() (5-{4-[Bis-(2-chloro-ethyl)-amino]-benzoylamino}-1H...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Ferrara Curated by ChEMBL | Assay Description Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) products | J Med Chem 43: 2675-84 (2000) BindingDB Entry DOI: 10.7270/Q2959J79 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50089962![]() (5-{4-[Bis-(2-chloro-ethyl)-amino]-benzoylamino}-be...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Ferrara Curated by ChEMBL | Assay Description Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) products | J Med Chem 43: 2675-84 (2000) BindingDB Entry DOI: 10.7270/Q2959J79 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50089969![]() (5-[Bis-(2-chloro-ethyl)-amino]-benzofuran-2-carbox...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Ferrara Curated by ChEMBL | Assay Description Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) products | J Med Chem 43: 2675-84 (2000) BindingDB Entry DOI: 10.7270/Q2959J79 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50089961![]() (5-{4-[Bis-(2-chloro-ethyl)-amino]-benzoylamino}-1-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Ferrara Curated by ChEMBL | Assay Description Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) products | J Med Chem 43: 2675-84 (2000) BindingDB Entry DOI: 10.7270/Q2959J79 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50089967![]() (5-{4-[Bis-(2-chloro-ethyl)-amino]-benzoylamino}-1H...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Ferrara Curated by ChEMBL | Assay Description Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) products | J Med Chem 43: 2675-84 (2000) BindingDB Entry DOI: 10.7270/Q2959J79 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50089978![]() (5-[Bis-(2-chloro-ethyl)-amino]-1H-indole-2-carboxy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Ferrara Curated by ChEMBL | Assay Description Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) products | J Med Chem 43: 2675-84 (2000) BindingDB Entry DOI: 10.7270/Q2959J79 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50089971![]() (5-[Bis-(2-chloro-ethyl)-amino]-1-methyl-1H-indole-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Ferrara Curated by ChEMBL | Assay Description Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) products | J Med Chem 43: 2675-84 (2000) BindingDB Entry DOI: 10.7270/Q2959J79 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50060139![]() (CHEMBL326352 | [(S)-1-((4-Benzyloxy-benzyl)-{[(1-p...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 88 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company Curated by ChEMBL | Assay Description Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells . | J Med Chem 40: 3319-22 (1997) Article DOI: 10.1021/jm970470c BindingDB Entry DOI: 10.7270/Q2V69HQG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50060146![]() (CHEMBL407445 | [(S)-1-((4-Benzyloxy-benzyl)-{[(1-p...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company Curated by ChEMBL | Assay Description Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells . | J Med Chem 40: 3319-22 (1997) Article DOI: 10.1021/jm970470c BindingDB Entry DOI: 10.7270/Q2V69HQG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50060141![]() (CHEMBL431440 | [(S)-1-{(4-Benzyloxy-benzyl)-[(2-me...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company Curated by ChEMBL | Assay Description Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells . | J Med Chem 40: 3319-22 (1997) Article DOI: 10.1021/jm970470c BindingDB Entry DOI: 10.7270/Q2V69HQG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50060140![]() (CHEMBL115943 | [(S)-1-{(4-Benzyloxy-benzyl)-[(2-cy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company Curated by ChEMBL | Assay Description Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells . | J Med Chem 40: 3319-22 (1997) Article DOI: 10.1021/jm970470c BindingDB Entry DOI: 10.7270/Q2V69HQG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50055659![]() (2N-(3,3-aminoiminopropyl)-4-[4-(4-formamido-1-meth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents | PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Ferrara Curated by ChEMBL | Assay Description Tested for 50% inhibition of generation of Human Ha-ras polymerase chain reaction(PCR) products | J Med Chem 43: 2675-84 (2000) BindingDB Entry DOI: 10.7270/Q2959J79 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50060145![]() (CHEMBL115669 | [(S)-1-{(4-Benzyloxy-benzyl)-[((S)-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company Curated by ChEMBL | Assay Description Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells . | J Med Chem 40: 3319-22 (1997) Article DOI: 10.1021/jm970470c BindingDB Entry DOI: 10.7270/Q2V69HQG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50060138![]() (CHEMBL324827 | [(S)-1-{(4-Benzyloxy-benzyl)-[(2-ph...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 310 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company Curated by ChEMBL | Assay Description Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells . | J Med Chem 40: 3319-22 (1997) Article DOI: 10.1021/jm970470c BindingDB Entry DOI: 10.7270/Q2V69HQG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50060142![]() (CHEMBL326127 | [(S)-1-((4-Benzyloxy-benzyl)-{[(1-p...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company Curated by ChEMBL | Assay Description Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells . | J Med Chem 40: 3319-22 (1997) Article DOI: 10.1021/jm970470c BindingDB Entry DOI: 10.7270/Q2V69HQG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50060149![]() (CHEMBL112512 | [(S)-1-{(4-Benzyloxy-benzyl)-[(2-ph...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company Curated by ChEMBL | Assay Description Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells . | J Med Chem 40: 3319-22 (1997) Article DOI: 10.1021/jm970470c BindingDB Entry DOI: 10.7270/Q2V69HQG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50060150![]() (CHEMBL114281 | [(S)-1-{(4-Benzyloxy-benzyl)-[((R)-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 570 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company Curated by ChEMBL | Assay Description Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells . | J Med Chem 40: 3319-22 (1997) Article DOI: 10.1021/jm970470c BindingDB Entry DOI: 10.7270/Q2V69HQG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50060144![]() (CHEMBL325073 | [(S)-1-{(4-Benzyloxy-benzyl)-[((R)-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 710 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company Curated by ChEMBL | Assay Description Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells . | J Med Chem 40: 3319-22 (1997) Article DOI: 10.1021/jm970470c BindingDB Entry DOI: 10.7270/Q2V69HQG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50060152![]() (CHEMBL112879 | [(S)-1-{(4-Benzyloxy-benzyl)-[(2-et...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company Curated by ChEMBL | Assay Description Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells . | J Med Chem 40: 3319-22 (1997) Article DOI: 10.1021/jm970470c BindingDB Entry DOI: 10.7270/Q2V69HQG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50287960![]() (1-[(2R,6S)-6-(tert-Butyl-dimethyl-silanyloxymethyl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of nucleotide exchange process of oncogenic Ras in vitro | Bioorg Med Chem Lett 6: 195-200 (1996) Article DOI: 10.1016/0960-894X(95)00574-D BindingDB Entry DOI: 10.7270/Q2G160TB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50060148![]() (CHEMBL325331 | [(S)-1-{(4-Benzyloxy-benzyl)-[(2-ph...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company Curated by ChEMBL | Assay Description Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells . | J Med Chem 40: 3319-22 (1997) Article DOI: 10.1021/jm970470c BindingDB Entry DOI: 10.7270/Q2V69HQG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50287951![]() (3-[(3aS,4R,6R,6aR)-6-(4-Chloro-6-methoxy-3-methyl-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid UniChem | Article | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of nucleotide exchange process of oncogenic Ras in vitro | Bioorg Med Chem Lett 6: 195-200 (1996) Article DOI: 10.1016/0960-894X(95)00574-D BindingDB Entry DOI: 10.7270/Q2G160TB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50287961![]() ((E)-5-[(2R,6R)-6-(4-Chloro-6-methoxy-3-methyl-pyra...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of nucleotide exchange process of oncogenic Ras in vitro | Bioorg Med Chem Lett 6: 195-200 (1996) Article DOI: 10.1016/0960-894X(95)00574-D BindingDB Entry DOI: 10.7270/Q2G160TB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50059857![]() (CHEMBL102955 | [(S)-1-[(4-Benzyloxy-benzyl)-(phene...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company Curated by ChEMBL | Assay Description Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells . | J Med Chem 40: 3319-22 (1997) Article DOI: 10.1021/jm970470c BindingDB Entry DOI: 10.7270/Q2V69HQG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50287943![]() ((E)-4-[(2R,6R)-6-(4-Chloro-6-methoxy-3-methyl-pyra...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article | n/a | n/a | 4.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of nucleotide exchange process of oncogenic Ras in vitro | Bioorg Med Chem Lett 6: 195-200 (1996) Article DOI: 10.1016/0960-894X(95)00574-D BindingDB Entry DOI: 10.7270/Q2G160TB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50287946![]() (1-[(2R,6S)-6-(tert-Butyl-dimethyl-silanyloxymethyl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of nucleotide exchange process of oncogenic Ras in vitro | Bioorg Med Chem Lett 6: 195-200 (1996) Article DOI: 10.1016/0960-894X(95)00574-D BindingDB Entry DOI: 10.7270/Q2G160TB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50060143![]() (CHEMBL324345 | [(S)-1-{(4-Benzyloxy-benzyl)-[((S)-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company Curated by ChEMBL | Assay Description Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells . | J Med Chem 40: 3319-22 (1997) Article DOI: 10.1021/jm970470c BindingDB Entry DOI: 10.7270/Q2V69HQG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50287963![]() (CHEMBL300769 | [(2S,6R)-6-(4-Chloro-6-methoxy-3-me...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article | n/a | n/a | 6.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of nucleotide exchange process of oncogenic Ras in vitro | Bioorg Med Chem Lett 6: 195-200 (1996) Article DOI: 10.1016/0960-894X(95)00574-D BindingDB Entry DOI: 10.7270/Q2G160TB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50287959![]() ((E)-4-[(2R,6R)-6-(4-Chloro-6-methoxy-3-methyl-pyra...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article | n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of nucleotide exchange process of oncogenic Ras in vitro | Bioorg Med Chem Lett 6: 195-200 (1996) Article DOI: 10.1016/0960-894X(95)00574-D BindingDB Entry DOI: 10.7270/Q2G160TB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50287955![]() ((E)-4-[(2R,6R)-6-(4-Chloro-6-methoxy-3-methyl-pyra...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article | n/a | n/a | 7.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of nucleotide exchange process of oncogenic Ras in vitro | Bioorg Med Chem Lett 6: 195-200 (1996) Article DOI: 10.1016/0960-894X(95)00574-D BindingDB Entry DOI: 10.7270/Q2G160TB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50287958![]() (CHEMBL303105 | [(2S,6R)-6-(4-Chloro-6-methoxy-3-me...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article | n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of nucleotide exchange process of oncogenic Ras in vitro | Bioorg Med Chem Lett 6: 195-200 (1996) Article DOI: 10.1016/0960-894X(95)00574-D BindingDB Entry DOI: 10.7270/Q2G160TB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50072339![]() (Benzodiazepine-Distamycin Hybrid | CHEMBL102341) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Ferrara Curated by ChEMBL | Assay Description Inhibition of Ha-ras polymerase-chain reaction product | Bioorg Med Chem Lett 8: 3019-24 (1999) Article DOI: 10.1016/S0960-894X(98)00544-7 BindingDB Entry DOI: 10.7270/Q2057GFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50287944![]() ((E)-3-[(2S,3S,4R,5R)-5-(4-Chloro-6-methoxy-3-methy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of nucleotide exchange process of oncogenic Ras in vitro | Bioorg Med Chem Lett 6: 195-200 (1996) Article DOI: 10.1016/0960-894X(95)00574-D BindingDB Entry DOI: 10.7270/Q2G160TB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50287945![]() (5-(4-chloro-6-methoxy-3-methyl-1H-pyrazolo[3,4-b]q...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro for inhibition of nucleotide exchange process of oncogenic Ras | Bioorg Med Chem Lett 6: 195-200 (1996) Article DOI: 10.1016/0960-894X(95)00574-D BindingDB Entry DOI: 10.7270/Q2G160TB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50287953![]() (5-(4-chloro-6-methoxy-3-methyl-1H-pyrazolo[3,4-b]q...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article | n/a | n/a | 1.05E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of nucleotide exchange process of oncogenic Ras in vitro | Bioorg Med Chem Lett 6: 195-200 (1996) Article DOI: 10.1016/0960-894X(95)00574-D BindingDB Entry DOI: 10.7270/Q2G160TB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50287962![]() (CHEMBL61870 | [(2S,6R)-4-Benzenesulfonyl-6-(4-chlo...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of nucleotide exchange process of oncogenic Ras in vitro | Bioorg Med Chem Lett 6: 195-200 (1996) Article DOI: 10.1016/0960-894X(95)00574-D BindingDB Entry DOI: 10.7270/Q2G160TB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50287949![]() (1-[(2R,6S)-4-Benzenesulfonyl-6-(tert-butyl-dimethy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article | n/a | n/a | 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of nucleotide exchange process of oncogenic Ras in vitro | Bioorg Med Chem Lett 6: 195-200 (1996) Article DOI: 10.1016/0960-894X(95)00574-D BindingDB Entry DOI: 10.7270/Q2G160TB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50287948![]() (CHEMBL64886 | [(2S,6R)-6-(4-Chloro-6-methoxy-3-met...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article | n/a | n/a | 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of nucleotide exchange process of oncogenic Ras in vitro | Bioorg Med Chem Lett 6: 195-200 (1996) Article DOI: 10.1016/0960-894X(95)00574-D BindingDB Entry DOI: 10.7270/Q2G160TB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50059879![]() (CHEMBL102492 | [(S)-1-{(4-Benzyloxy-benzyl)-[(2-be...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 1.43E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company Curated by ChEMBL | Assay Description Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells . | J Med Chem 40: 3319-22 (1997) Article DOI: 10.1021/jm970470c BindingDB Entry DOI: 10.7270/Q2V69HQG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50287956![]() (Benzoic acid (3aR,4R,6R,6aR)-6-(4-chloro-6-methoxy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article | n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of nucleotide exchange process of oncogenic Ras in vitro | Bioorg Med Chem Lett 6: 195-200 (1996) Article DOI: 10.1016/0960-894X(95)00574-D BindingDB Entry DOI: 10.7270/Q2G160TB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50287947![]() ((E)-4-[(2R,6R)-6-(4-Chloro-6-methoxy-3-methyl-pyra...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article | n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of nucleotide exchange process of oncogenic Ras in vitro | Bioorg Med Chem Lett 6: 195-200 (1996) Article DOI: 10.1016/0960-894X(95)00574-D BindingDB Entry DOI: 10.7270/Q2G160TB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50287952![]() (CHEMBL304717 | N-{4-[(2S,6R)-2-(tert-Butyl-dimethy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article | n/a | n/a | 2.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of nucleotide exchange process of oncogenic Ras in vitro | Bioorg Med Chem Lett 6: 195-200 (1996) Article DOI: 10.1016/0960-894X(95)00574-D BindingDB Entry DOI: 10.7270/Q2G160TB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50287954![]() ((E)-3-[(2S,5R)-5-(4-Chloro-6-methoxy-3-methyl-pyra...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article | n/a | n/a | 3.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of nucleotide exchange process of oncogenic Ras in vitro | Bioorg Med Chem Lett 6: 195-200 (1996) Article DOI: 10.1016/0960-894X(95)00574-D BindingDB Entry DOI: 10.7270/Q2G160TB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50287957![]() (1-[(2R,6S)-6-(tert-Butyl-dimethyl-silanyloxymethyl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article | n/a | n/a | 5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of nucleotide exchange process of oncogenic Ras in vitro | Bioorg Med Chem Lett 6: 195-200 (1996) Article DOI: 10.1016/0960-894X(95)00574-D BindingDB Entry DOI: 10.7270/Q2G160TB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50287950![]() (Benzoic acid (2S,5R)-5-(4-chloro-6-methoxy-3-methy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article | n/a | n/a | 8.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of nucleotide exchange process of oncogenic Ras in vitro | Bioorg Med Chem Lett 6: 195-200 (1996) Article DOI: 10.1016/0960-894X(95)00574-D BindingDB Entry DOI: 10.7270/Q2G160TB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50055659![]() (2N-(3,3-aminoiminopropyl)-4-[4-(4-formamido-1-meth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Ferrara Curated by ChEMBL | Bioorg Med Chem Lett 8: 3019-24 (1999) Article DOI: 10.1016/S0960-894X(98)00544-7 BindingDB Entry DOI: 10.7270/Q2057GFM | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50055659![]() (2N-(3,3-aminoiminopropyl)-4-[4-(4-formamido-1-meth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Ferrara Curated by ChEMBL | Assay Description Inhibition of Ha-ras polymerase-chain reaction product | Bioorg Med Chem Lett 8: 3019-24 (1999) Article DOI: 10.1016/S0960-894X(98)00544-7 BindingDB Entry DOI: 10.7270/Q2057GFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50072338![]() (3-((S)-7-Methoxy-5-oxo-2,3,5,11a-tetrahydro-1H-ben...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Ferrara Curated by ChEMBL | Assay Description Inhibition of Ha-ras polymerase-chain reaction product | Bioorg Med Chem Lett 8: 3019-24 (1999) Article DOI: 10.1016/S0960-894X(98)00544-7 BindingDB Entry DOI: 10.7270/Q2057GFM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50421182![]() (CHEMBL2086797) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 2.80E+4 | n/a | n/a | n/a | n/a | n/a |
Genentech Curated by ChEMBL | Assay Description Binding affinity to His6-tagged HRas expressed in Escherichia coli (BL21) by fluorescence polarization assay | Bioorg Med Chem Lett 22: 5766-76 (2012) Article DOI: 10.1016/j.bmcl.2012.07.082 BindingDB Entry DOI: 10.7270/Q2RR20JZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GTPase HRas (Homo sapiens (Human)) | BDBM50421182![]() (CHEMBL2086797) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 1.58E+5 | n/a | n/a | n/a | n/a | n/a |
Genentech Curated by ChEMBL | Assay Description Binding affinity to His6-tagged HRas-GDP expressed in Escherichia coli (BL21) by fluorescence polarization assay | Bioorg Med Chem Lett 22: 5766-76 (2012) Article DOI: 10.1016/j.bmcl.2012.07.082 BindingDB Entry DOI: 10.7270/Q2RR20JZ | |||||||||||
More data for this Ligand-Target Pair |