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Compile Data Set for Download or QSAR

Found 756 hits Enz. Inhib. hit(s) with Target = 'Liver glycogen phosphorylase'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM50148913
PNG
(CHEMBL3770455)
Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1nc(c[nH]1)-c1ccc2ccccc2c1 |r|
Show InChI InChI=1/C19H20N2O5/c22-9-14-15(23)16(24)17(25)18(26-14)19-20-8-13(21-19)12-6-5-10-3-1-2-4-11(10)7-12/h1-8,14-18,22-25H,9H2,(H,20,21)/t14-,15-,16+,17-,18-/s2
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26n/an/an/an/an/an/an/an/a



University of Thessaly

Curated by ChEMBL


Assay Description
Competitive inhibition of His6-tagged human liver glycogen phosphorylase-a expressed in Escherichia coli BL21 Gold (DE3) assessed as release of inorg...


Eur J Med Chem 123: 737-745 (2016)


Article DOI: 10.1016/j.ejmech.2016.06.049
More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM50148915
PNG
(CHEMBL3770514)
Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1nc(c[nH]1)-c1ccccc1 |r|
Show InChI InChI=1/C15H18N2O5/c18-7-10-11(19)12(20)13(21)14(22-10)15-16-6-9(17-15)8-4-2-1-3-5-8/h1-6,10-14,18-21H,7H2,(H,16,17)/t10-,11-,12+,13-,14-/s2
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156n/an/an/an/an/an/an/an/a



University of Thessaly

Curated by ChEMBL


Assay Description
Competitive inhibition of His6-tagged human liver glycogen phosphorylase-a expressed in Escherichia coli BL21 Gold (DE3) assessed as release of inorg...


Eur J Med Chem 123: 737-745 (2016)


Article DOI: 10.1016/j.ejmech.2016.06.049
More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM50016703
PNG
(2-Hydroxymethyl-pyrrolidine-3,4-diol | BDBM5003148...)
Show SMILES OC[C@H]1NC[C@@H](O)C1O
Show InChI InChI=1S/C5H11NO3/c7-2-3-5(9)4(8)1-6-3/h3-9H,1-2H2/t3-,4-,5?/m1/s1
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400n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibitory activity against pig Liver glycogen phosphorylase a


J Med Chem 47: 3537-45 (2004)


Article DOI: 10.1021/jm031121n
More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM50211296
PNG
((7R,8S,9S,10R)-8,9,10-trihydroxy-7-hydroxymethyl-6...)
Show SMILES OC[C@H]1OC2(NC(=O)NC2=O)[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C8H12N2O7/c11-1-2-3(12)4(13)5(14)8(17-2)6(15)9-7(16)10-8/h2-5,11-14H,1H2,(H2,9,10,15,16)/t2-,3-,4+,5-,8?/m1/s1
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4.20E+3n/an/an/an/an/an/an/an/a



University of Debrecen

Curated by ChEMBL


Assay Description
Inhibition of liver glycogen phosphorylase B


Bioorg Med Chem 15: 4048-56 (2007)


Article DOI: 10.1016/j.bmc.2007.03.084
More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM50211294
PNG
((7R,8S,9S,10R)-8,9,10-trihydroxy-7-hydroxymethyl-2...)
Show SMILES OC[C@H]1OC2(NC(=S)NC2=O)[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C8H12N2O6S/c11-1-2-3(12)4(13)5(14)8(16-2)6(15)9-7(17)10-8/h2-5,11-14H,1H2,(H2,9,10,15,17)/t2-,3-,4+,5-,8?/m1/s1
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5.10E+3n/an/an/an/an/an/an/an/a



University of Debrecen

Curated by ChEMBL


Assay Description
Inhibition of liver glycogen phosphorylase B


Bioorg Med Chem 15: 4048-56 (2007)


Article DOI: 10.1016/j.bmc.2007.03.084
More data for this
Ligand-Target Pair
Liver glycogen phosphorylase


(Rattus norvegicus)
BDBM50263769
PNG
((5S,7R,8S,9S,10R)-8,9,10-Trihydroxy-7-hydroxymethy...)
Show SMILES OC[C@H]1O[C@@]2(NC(=S)NC2=O)[C@H](O)[C@@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C8H12N2O6S/c11-1-2-3(12)4(13)5(14)8(16-2)6(15)9-7(17)10-8/h2-5,11-14H,1H2,(H2,9,10,15,17)/t2-,3-,4+,5-,8+/m1/s1
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7.00E+3n/an/an/an/an/an/an/an/a



Lajos Kossuth University

Curated by ChEMBL




Bioorg Med Chem Lett 9: 1385-90 (1999)

More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM50263769
PNG
((5S,7R,8S,9S,10R)-8,9,10-Trihydroxy-7-hydroxymethy...)
Show SMILES OC[C@H]1O[C@@]2(NC(=S)NC2=O)[C@H](O)[C@@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C8H12N2O6S/c11-1-2-3(12)4(13)5(14)8(16-2)6(15)9-7(17)10-8/h2-5,11-14H,1H2,(H2,9,10,15,17)/t2-,3-,4+,5-,8+/m1/s1
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1.09E+4n/an/an/an/an/an/an/an/a



University of Debrecen

Curated by ChEMBL


Assay Description
Inhibitory activity against muscle Glycogen Phosphorylase a


J Med Chem 44: 2843-8 (2001)

More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM50211289
PNG
(5-[4-(6,7-dibromo-2,3-dihydrobenzo[1,4]dioxin-2-yl...)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCC2COc3cc(Br)c(Br)cc3O2)cc1 |w:7.8,t:1|
Show InChI InChI=1S/C19H13Br2NO5S/c20-13-6-15-16(7-14(13)21)27-12(9-26-15)8-25-11-3-1-10(2-4-11)5-17-18(23)22-19(24)28-17/h1-7,12H,8-9H2,(H,22,23,24)
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1.20E+4n/an/an/an/an/an/an/an/a



University of Debrecen

Curated by ChEMBL


Assay Description
Inhibition of liver glycogen phosphorylase B


Bioorg Med Chem 15: 4048-56 (2007)


Article DOI: 10.1016/j.bmc.2007.03.084
More data for this
Ligand-Target Pair
Liver glycogen phosphorylase


(Rattus norvegicus)
BDBM50215446
PNG
(CHEMBL3351144)
Show SMILES OC[C@@H]1O[C@@]2(NC(=O)NC2=O)[C@@H](O)[C@@H](O)[C@@H]1O |r|
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1.28E+4n/an/an/an/an/an/an/an/a



Lajos Kossuth University

Curated by ChEMBL




Bioorg Med Chem Lett 9: 1385-90 (1999)

More data for this
Ligand-Target Pair
Liver glycogen phosphorylase


(Rattus norvegicus)
BDBM50215446
PNG
(CHEMBL3351144)
Show SMILES OC[C@@H]1O[C@@]2(NC(=O)NC2=O)[C@@H](O)[C@@H](O)[C@@H]1O |r|
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1.65E+4n/an/an/an/an/an/an/an/a



Lajos Kossuth University

Curated by ChEMBL


Assay Description
Inhibitor constant was measured against Liver phosphorylase b in rat


Bioorg Med Chem Lett 9: 1385-90 (1999)

More data for this
Ligand-Target Pair
Liver glycogen phosphorylase


(Rattus norvegicus)
BDBM50263769
PNG
((5S,7R,8S,9S,10R)-8,9,10-Trihydroxy-7-hydroxymethy...)
Show SMILES OC[C@H]1O[C@@]2(NC(=S)NC2=O)[C@H](O)[C@@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C8H12N2O6S/c11-1-2-3(12)4(13)5(14)8(16-2)6(15)9-7(17)10-8/h2-5,11-14H,1H2,(H2,9,10,15,17)/t2-,3-,4+,5-,8+/m1/s1
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2.98E+4n/an/an/an/an/an/an/an/a



Lajos Kossuth University

Curated by ChEMBL


Assay Description
Inhibitor constant was measured against Liver phosphorylase a in rat


Bioorg Med Chem Lett 9: 1385-90 (1999)

More data for this
Ligand-Target Pair
Liver glycogen phosphorylase


(Rattus norvegicus)
BDBM50211294
PNG
((7R,8S,9S,10R)-8,9,10-trihydroxy-7-hydroxymethyl-2...)
Show SMILES OC[C@H]1OC2(NC(=S)NC2=O)[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C8H12N2O6S/c11-1-2-3(12)4(13)5(14)8(16-2)6(15)9-7(17)10-8/h2-5,11-14H,1H2,(H2,9,10,15,17)/t2-,3-,4+,5-,8?/m1/s1
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2.98E+4n/an/an/an/an/an/an/an/a



University of Debrecen

Curated by ChEMBL


Assay Description
Inhibition of rat liver glycogen phosphorylase


Eur J Med Chem 76: 567-79 (2014)


Article DOI: 10.1016/j.ejmech.2014.02.041
More data for this
Ligand-Target Pair
Liver glycogen phosphorylase


(Rattus norvegicus)
BDBM50211294
PNG
((7R,8S,9S,10R)-8,9,10-trihydroxy-7-hydroxymethyl-2...)
Show SMILES OC[C@H]1OC2(NC(=S)NC2=O)[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C8H12N2O6S/c11-1-2-3(12)4(13)5(14)8(16-2)6(15)9-7(17)10-8/h2-5,11-14H,1H2,(H2,9,10,15,17)/t2-,3-,4+,5-,8?/m1/s1
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2.98E+4n/an/an/an/an/an/an/an/a



Department of Organic Chemistry, University of Debrecen , POB 20, H-4010 Debrecen, Hungary.

Curated by ChEMBL


Assay Description
Inhibition of rat liver glycogen phosphorylase


ACS Med Chem Lett 4: 612-5 (2013)


Article DOI: 10.1021/ml4001529
More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM50263769
PNG
((5S,7R,8S,9S,10R)-8,9,10-Trihydroxy-7-hydroxymethy...)
Show SMILES OC[C@H]1O[C@@]2(NC(=S)NC2=O)[C@H](O)[C@@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C8H12N2O6S/c11-1-2-3(12)4(13)5(14)8(16-2)6(15)9-7(17)10-8/h2-5,11-14H,1H2,(H2,9,10,15,17)/t2-,3-,4+,5-,8+/m1/s1
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2.98E+4n/an/an/an/an/an/an/an/a



University of Debrecen

Curated by ChEMBL


Assay Description
Inhibitory activity against liver Glycogen Phosphorylase a


J Med Chem 44: 2843-8 (2001)

More data for this
Ligand-Target Pair
Liver glycogen phosphorylase


(Rattus norvegicus)
BDBM50263769
PNG
((5S,7R,8S,9S,10R)-8,9,10-Trihydroxy-7-hydroxymethy...)
Show SMILES OC[C@H]1O[C@@]2(NC(=S)NC2=O)[C@H](O)[C@@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C8H12N2O6S/c11-1-2-3(12)4(13)5(14)8(16-2)6(15)9-7(17)10-8/h2-5,11-14H,1H2,(H2,9,10,15,17)/t2-,3-,4+,5-,8+/m1/s1
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2.98E+4n/an/an/an/an/an/an/an/a



University of Debrecen

Curated by ChEMBL


Assay Description
Inhibition of rat liver glycogen phosphorylase


ACS Med Chem Lett 6: 1215-9 (2015)

More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM50211288
PNG
(5-[4-(6,7-dibromo-2,3-dihydrobenzo[1,4]dioxin-2-yl...)
Show SMILES COc1cc(C=C2SC(O)=NC2=O)ccc1OCC1COc2cc(Br)c(Br)cc2O1 |w:5.4,c:9|
Show InChI InChI=1S/C20H15Br2NO6S/c1-26-15-4-10(5-18-19(24)23-20(25)30-18)2-3-14(15)27-8-11-9-28-16-6-12(21)13(22)7-17(16)29-11/h2-7,11H,8-9H2,1H3,(H,23,24,25)
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3.00E+4n/an/an/an/an/an/an/an/a



University of Debrecen

Curated by ChEMBL


Assay Description
Inhibition of liver glycogen phosphorylase B


Bioorg Med Chem 15: 4048-56 (2007)


Article DOI: 10.1016/j.bmc.2007.03.084
More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM50211286
PNG
(5-[4-(6-bromo-2,3-dihydrobenzo[1,4]dioxin-2-ylmeth...)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCC2COc3cc(Br)ccc3O2)cc1 |w:7.8,t:1|
Show InChI InChI=1S/C19H14BrNO5S/c20-12-3-6-15-16(8-12)25-10-14(26-15)9-24-13-4-1-11(2-5-13)7-17-18(22)21-19(23)27-17/h1-8,14H,9-10H2,(H,21,22,23)
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8.00E+4n/an/an/an/an/an/an/an/a



University of Debrecen

Curated by ChEMBL


Assay Description
Inhibition of liver glycogen phosphorylase B


Bioorg Med Chem 15: 4048-56 (2007)


Article DOI: 10.1016/j.bmc.2007.03.084
More data for this
Ligand-Target Pair
Liver glycogen phosphorylase


(Rattus norvegicus)
BDBM50215446
PNG
(CHEMBL3351144)
Show SMILES OC[C@@H]1O[C@@]2(NC(=O)NC2=O)[C@@H](O)[C@@H](O)[C@@H]1O |r|
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2.05E+6n/an/an/an/an/an/an/an/a



Lajos Kossuth University

Curated by ChEMBL


Assay Description
Inhibitor constant was measured against Liver phosphorylase a in rat


Bioorg Med Chem Lett 9: 1385-90 (1999)

More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM50351158
PNG
(CHEMBL423707)
Show SMILES OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1
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4.28E+6n/an/an/an/an/an/an/an/a



University of Thessaly

Curated by ChEMBL


Assay Description
Competitive inhibition of His6-tagged human liver glycogen phosphorylase-a expressed in Escherichia coli BL21 Gold (DE3) assessed as release of inorg...


Eur J Med Chem 123: 737-745 (2016)


Article DOI: 10.1016/j.ejmech.2016.06.049
More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM50351158
PNG
(CHEMBL423707)
Show SMILES OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1
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4.90E+6n/an/an/an/an/an/an/an/a



University of Thessaly

Curated by ChEMBL


Assay Description
Inhibition of glycogen phosphorylase a (unknown origin)


Bioorg Med Chem 22: 4810-25 (2014)


Article DOI: 10.1016/j.bmc.2014.06.058
More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM50135554
PNG
(4-{3-[(4-Nitro-pyridine-2-carbonyl)-amino]-naphtha...)
Show SMILES OC(=O)c1ccc(Oc2cc3ccccc3cc2NC(=O)c2cc(ccn2)[N+]([O-])=O)cc1C(O)=O
Show InChI InChI=1S/C24H15N3O8/c28-22(20-11-15(27(33)34)7-8-25-20)26-19-9-13-3-1-2-4-14(13)10-21(19)35-16-5-6-17(23(29)30)18(12-16)24(31)32/h1-12H,(H,26,28)(H,29,30)(H,31,32)
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n/an/a 1n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibitory activity against HLGP(human liver glycogen phosphorylase)


Bioorg Med Chem Lett 13: 4125-8 (2003)

More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM50135558
PNG
(4-{3-Fluoro-2-[(4-nitro-pyridine-2-carbonyl)-amino...)
Show SMILES OC(=O)c1ccc(Oc2cccc(F)c2NC(=O)c2cc(ccn2)[N+]([O-])=O)cc1C(O)=O
Show InChI InChI=1S/C20H12FN3O8/c21-14-2-1-3-16(32-11-4-5-12(19(26)27)13(9-11)20(28)29)17(14)23-18(25)15-8-10(24(30)31)6-7-22-15/h1-9H,(H,23,25)(H,26,27)(H,28,29)
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n/an/a 1n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibitory activity against HLGP(human liver glycogen phosphorylase)


Bioorg Med Chem Lett 13: 4125-8 (2003)

More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM50133440
PNG
(1-(4-Chloro-benzyl)-4-(2-chloro-phenyl)-6-methyl-1...)
Show SMILES CC(C)OC(=O)C1=C(C)N(Cc2ccc(Cl)cc2)C(C(O)=O)=C(C1c1ccccc1Cl)C(O)=O |c:6,22|
Show InChI InChI=1S/C25H23Cl2NO6/c1-13(2)34-25(33)19-14(3)28(12-15-8-10-16(26)11-9-15)22(24(31)32)21(23(29)30)20(19)17-6-4-5-7-18(17)27/h4-11,13,20H,12H2,1-3H3,(H,29,30)(H,31,32)
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n/an/a 2n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human liver glycogen phosphorylase a (HLGPa)


Bioorg Med Chem Lett 13: 3405-8 (2003)

More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM50135553
PNG
(4-{3-[(4-Chloro-pyridine-2-carbonyl)-amino]-naphth...)
Show SMILES OC(=O)c1ccc(Oc2cc3ccccc3cc2NC(=O)c2cc(Cl)ccn2)cc1C(O)=O
Show InChI InChI=1S/C24H15ClN2O6/c25-15-7-8-26-20(11-15)22(28)27-19-9-13-3-1-2-4-14(13)10-21(19)33-16-5-6-17(23(29)30)18(12-16)24(31)32/h1-12H,(H,27,28)(H,29,30)(H,31,32)
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n/an/a 2n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibitory activity against HLGP(human liver glycogen phosphorylase)


Bioorg Med Chem Lett 13: 4125-8 (2003)

More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM50135565
PNG
(4-{3-[(4-Methoxy-pyridine-2-carbonyl)-amino]-napht...)
Show SMILES COc1ccnc(c1)C(=O)Nc1cc2ccccc2cc1Oc1ccc(C(O)=O)c(c1)C(O)=O
Show InChI InChI=1S/C25H18N2O7/c1-33-16-8-9-26-21(13-16)23(28)27-20-10-14-4-2-3-5-15(14)11-22(20)34-17-6-7-18(24(29)30)19(12-17)25(31)32/h2-13H,1H3,(H,27,28)(H,29,30)(H,31,32)
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n/an/a 2n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibitory activity against HLGP(human liver glycogen phosphorylase)


Bioorg Med Chem Lett 13: 4125-8 (2003)

More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM24393
PNG
(2,3-dichloro-N-{1-[(2R)-2,3-dihydroxypropyl]-2-oxo...)
Show SMILES OC[C@H](O)CN1C(=O)C(Cc2ccccc12)NC(=O)c1cc2sc(Cl)c(Cl)c2[nH]1 |r|
Show InChI InChI=1S/C19H17Cl2N3O4S/c20-15-16-14(29-17(15)21)6-11(22-16)18(27)23-12-5-9-3-1-2-4-13(9)24(19(12)28)7-10(26)8-25/h1-4,6,10,12,22,25-26H,5,7-8H2,(H,23,27)/t10-,12?/m1/s1
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AstraZeneca



Assay Description
The inhibitory activity of the test compounds against human recombinant glycogen phosphorylase a (GPa) was monitored using 96-well microplate format....


Bioorg Med Chem Lett 17: 394-9 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.037
More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM50135562
PNG
(4-{2-[(4-Nitro-pyridine-2-carbonyl)-amino]-phenoxy...)
Show SMILES OC(=O)c1ccc(Oc2ccccc2NC(=O)c2cc(ccn2)[N+]([O-])=O)cc1C(O)=O
Show InChI InChI=1S/C20H13N3O8/c24-18(16-9-11(23(29)30)7-8-21-16)22-15-3-1-2-4-17(15)31-12-5-6-13(19(25)26)14(10-12)20(27)28/h1-10H,(H,22,24)(H,25,26)(H,27,28)
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n/an/a 3n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibitory activity against HLGP(human liver glycogen phosphorylase)


Bioorg Med Chem Lett 13: 4125-8 (2003)

More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM27730
PNG
((2S,3R)-3-(tert-butoxy)-2-{[4-(4-methoxyphenyl)-2-...)
Show SMILES COc1ccc(cc1)-c1ccc(C(=O)N[C@@H]([C@@H](C)OC(C)(C)C)C(O)=O)c(NC(=O)Nc2c(C)cc(C)cc2C)c1 |r|
Show InChI InChI=1S/C32H39N3O6/c1-18-15-19(2)27(20(3)16-18)35-31(39)33-26-17-23(22-9-12-24(40-8)13-10-22)11-14-25(26)29(36)34-28(30(37)38)21(4)41-32(5,6)7/h9-17,21,28H,1-8H3,(H,34,36)(H,37,38)(H2,33,35,39)/t21-,28+/m1/s1
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n/an/a 3n/an/an/an/a7.625



GSK



Assay Description
An enzymatic assay was developed to measure the response of the activated form of glycogen phosphorylase to small molecule compounds. The assay was t...


Bioorg Med Chem Lett 19: 1177-82 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.085
More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM27747
PNG
((2S,3R)-3-(tert-butoxy)-2-{[2-({[4-(cyclopropylmet...)
Show SMILES C[C@@H](OC(C)(C)C)[C@H](NC(=O)c1ccc(cc1NC(=O)Nc1c(C)cc(CC2CC2)cc1C)-c1cccc(F)c1)C(O)=O |r|
Show InChI InChI=1S/C34H40FN3O5/c1-19-14-23(16-22-10-11-22)15-20(2)29(19)38-33(42)36-28-18-25(24-8-7-9-26(35)17-24)12-13-27(28)31(39)37-30(32(40)41)21(3)43-34(4,5)6/h7-9,12-15,17-18,21-22,30H,10-11,16H2,1-6H3,(H,37,39)(H,40,41)(H2,36,38,42)/t21-,30+/m1/s1
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n/an/a 3n/an/an/an/a7.625



GSK



Assay Description
An enzymatic assay was developed to measure the response of the activated form of glycogen phosphorylase to small molecule compounds. The assay was t...


Bioorg Med Chem Lett 19: 1177-82 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.085
More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM50133438
PNG
(4-(2-Chloro-phenyl)-1-(3,4-dimethoxy-benzyl)-6-met...)
Show SMILES COc1ccc(CN2C(C)=C(C(C(C(O)=O)=C2C(O)=O)c2ccccc2Cl)C(=O)OC(C)C)cc1OC |c:9,15|
Show InChI InChI=1S/C27H28ClNO8/c1-14(2)37-27(34)21-15(3)29(13-16-10-11-19(35-4)20(12-16)36-5)24(26(32)33)23(25(30)31)22(21)17-8-6-7-9-18(17)28/h6-12,14,22H,13H2,1-5H3,(H,30,31)(H,32,33)
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n/an/a 4n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human liver glycogen phosphorylase a (HLGPa)


Bioorg Med Chem Lett 13: 3405-8 (2003)

More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM50135557
PNG
(4-{3-[(4-Ethyl-pyridine-2-carbonyl)-amino]-naphtha...)
Show SMILES CCc1ccnc(c1)C(=O)Nc1cc2ccccc2cc1Oc1ccc(C(O)=O)c(c1)C(O)=O
Show InChI InChI=1S/C26H20N2O6/c1-2-15-9-10-27-22(11-15)24(29)28-21-12-16-5-3-4-6-17(16)13-23(21)34-18-7-8-19(25(30)31)20(14-18)26(32)33/h3-14H,2H2,1H3,(H,28,29)(H,30,31)(H,32,33)
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n/an/a 4n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibitory activity against HLGP(human liver glycogen phosphorylase)


Bioorg Med Chem Lett 13: 4125-8 (2003)

More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM27743
PNG
((2S,3R)-3-(tert-butoxy)-2-{[2-({[4-(cyclopropylmet...)
Show SMILES C[C@@H](OC(C)(C)C)[C@H](NC(=O)c1ccc(F)cc1NC(=O)Nc1c(C)cc(CC2CC2)cc1C)C(O)=O |r|
Show InChI InChI=1S/C28H36FN3O5/c1-15-11-19(13-18-7-8-18)12-16(2)23(15)32-27(36)30-22-14-20(29)9-10-21(22)25(33)31-24(26(34)35)17(3)37-28(4,5)6/h9-12,14,17-18,24H,7-8,13H2,1-6H3,(H,31,33)(H,34,35)(H2,30,32,36)/t17-,24+/m1/s1
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n/an/a 4n/an/an/an/a7.625



GSK



Assay Description
An enzymatic assay was developed to measure the response of the activated form of glycogen phosphorylase to small molecule compounds. The assay was t...


Bioorg Med Chem Lett 19: 1177-82 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.085
More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM27745
PNG
((2S,3R)-3-(tert-butoxy)-2-[(2-{[(2,6-dimethyl-4-pr...)
Show SMILES CCCc1cc(C)c(NC(=O)Nc2cc(ccc2C(=O)N[C@@H]([C@@H](C)OC(C)(C)C)C(O)=O)-c2ccc(OC)cc2)c(C)c1 |r|
Show InChI InChI=1S/C34H43N3O6/c1-9-10-23-17-20(2)29(21(3)18-23)37-33(41)35-28-19-25(24-11-14-26(42-8)15-12-24)13-16-27(28)31(38)36-30(32(39)40)22(4)43-34(5,6)7/h11-19,22,30H,9-10H2,1-8H3,(H,36,38)(H,39,40)(H2,35,37,41)/t22-,30+/m1/s1
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GSK



Assay Description
An enzymatic assay was developed to measure the response of the activated form of glycogen phosphorylase to small molecule compounds. The assay was t...


Bioorg Med Chem Lett 19: 1177-82 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.085
More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM27746
PNG
((2S,3R)-3-(tert-butoxy)-2-[(2-{[(2,6-dimethyl-4-pr...)
Show SMILES CCCc1cc(C)c(NC(=O)Nc2cc(ccc2C(=O)N[C@@H]([C@@H](C)OC(C)(C)C)C(O)=O)-c2cccc(F)c2)c(C)c1 |r|
Show InChI InChI=1S/C33H40FN3O5/c1-8-10-22-15-19(2)28(20(3)16-22)37-32(41)35-27-18-24(23-11-9-12-25(34)17-23)13-14-26(27)30(38)36-29(31(39)40)21(4)42-33(5,6)7/h9,11-18,21,29H,8,10H2,1-7H3,(H,36,38)(H,39,40)(H2,35,37,41)/t21-,29+/m1/s1
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n/an/a 4n/an/an/an/a7.625



GSK



Assay Description
An enzymatic assay was developed to measure the response of the activated form of glycogen phosphorylase to small molecule compounds. The assay was t...


Bioorg Med Chem Lett 19: 1177-82 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.085
More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM50194411
PNG
((S)-2,3-dichloro-N-(1-(dimethylamino)-1-oxo-3-phen...)
Show SMILES CN(C)C(=O)[C@H](Cc1ccccc1)NC(=O)c1cc2sc(Cl)c(Cl)c2[nH]1
Show InChI InChI=1S/C18H17Cl2N3O2S/c1-23(2)18(25)12(8-10-6-4-3-5-7-10)22-17(24)11-9-13-15(21-11)14(19)16(20)26-13/h3-7,9,12,21H,8H2,1-2H3,(H,22,24)/t12-/m0/s1
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n/an/a 5n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of recombinant human liver GPa by multienzyme coupled assay


Bioorg Med Chem Lett 16: 5567-71 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.047
More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM50255975
PNG
((S)-2-cyclohexyl-2-(3-(3-(2,6-dichloro-4-(trifluor...)
Show SMILES OC(=O)[C@@H](NC(=O)c1cc2ccccc2cc1NC(=O)Nc1c(Cl)cc(OC(F)(F)F)cc1Cl)C1CCCCC1 |r|
Show InChI InChI=1S/C27H24Cl2F3N3O5/c28-19-12-17(40-27(30,31)32)13-20(29)23(19)35-26(39)33-21-11-16-9-5-4-8-15(16)10-18(21)24(36)34-22(25(37)38)14-6-2-1-3-7-14/h4-5,8-14,22H,1-3,6-7H2,(H,34,36)(H,37,38)(H2,33,35,39)/t22-/m0/s1
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of human liver glycogen phosphorylase A by fluorescence intensity endpoint assay in presence of glucose


Bioorg Med Chem Lett 19: 976-80 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.085
More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM50256329
PNG
(1-(3-(3-mesitylureido)-2-naphthamido)cyclooctaneca...)
Show SMILES Cc1cc(C)c(NC(=O)Nc2cc3ccccc3cc2C(=O)NC2(CCCCCCC2)C(O)=O)c(C)c1
Show InChI InChI=1S/C30H35N3O4/c1-19-15-20(2)26(21(3)16-19)32-29(37)31-25-18-23-12-8-7-11-22(23)17-24(25)27(34)33-30(28(35)36)13-9-5-4-6-10-14-30/h7-8,11-12,15-18H,4-6,9-10,13-14H2,1-3H3,(H,33,34)(H,35,36)(H2,31,32,37)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of human liver glycogen phosphorylase A by fluorescence intensity endpoint assay in presence of glucose


Bioorg Med Chem Lett 19: 976-80 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.085
More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM50133442
PNG
(4-(2-Chloro-phenyl)-6-methyl-1-(3-nitro-benzyl)-1,...)
Show SMILES CC(C)OC(=O)C1=C(C)N(Cc2cccc(c2)[N+]([O-])=O)C(C(O)=O)=C(C1c1ccccc1Cl)C(O)=O |c:6,24|
Show InChI InChI=1S/C25H23ClN2O8/c1-13(2)36-25(33)19-14(3)27(12-15-7-6-8-16(11-15)28(34)35)22(24(31)32)21(23(29)30)20(19)17-9-4-5-10-18(17)26/h4-11,13,20H,12H2,1-3H3,(H,29,30)(H,31,32)
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Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human liver glycogen phosphorylase a (HLGPa)


Bioorg Med Chem Lett 13: 3405-8 (2003)

More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM50256669
PNG
((2S,3R)-2-(3-(3-mesitylureido)-2-naphthamido)-3-(1...)
Show SMILES C[C@@H](OC1(C)CCCC1)[C@H](NC(=O)c1cc2ccccc2cc1NC(=O)Nc1c(C)cc(C)cc1C)C(O)=O |r|
Show InChI InChI=1S/C31H37N3O5/c1-18-14-19(2)26(20(3)15-18)34-30(38)32-25-17-23-11-7-6-10-22(23)16-24(25)28(35)33-27(29(36)37)21(4)39-31(5)12-8-9-13-31/h6-7,10-11,14-17,21,27H,8-9,12-13H2,1-5H3,(H,33,35)(H,36,37)(H2,32,34,38)/t21-,27+/m1/s1
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of human liver glycogen phosphorylase A by fluorescence plate reader assay


Bioorg Med Chem Lett 19: 981-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.084
More data for this
Ligand-Target Pair
Liver glycogen phosphorylase


(Mus musculus)
BDBM50149207
PNG
(2N-(2-{2-[2-(5-chloro-1H-2-indolylcarboxamido)etho...)
Show SMILES Clc1ccc2[nH]c(cc2c1)C(=O)NCCOCCOCCNC(=O)c1cc2cc(Cl)ccc2[nH]1
Show InChI InChI=1S/C24H24Cl2N4O4/c25-17-1-3-19-15(11-17)13-21(29-19)23(31)27-5-7-33-9-10-34-8-6-28-24(32)22-14-16-12-18(26)2-4-20(16)30-22/h1-4,11-14,29-30H,5-10H2,(H,27,31)(H,28,32)
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n/an/a 6n/an/an/an/an/an/a



Sunesis Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against glycogen phosphorylase


J Med Chem 47: 3463-82 (2004)


Article DOI: 10.1021/jm040031v
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM50255977
PNG
((S)-2-cyclohexyl-2-(3-(3-mesitylureido)-2-naphtham...)
Show SMILES Cc1cc(C)c(NC(=O)Nc2cc3ccccc3cc2C(=O)N[C@@H](C2CCCCC2)C(O)=O)c(C)c1 |r|
Show InChI InChI=1S/C29H33N3O4/c1-17-13-18(2)25(19(3)14-17)32-29(36)30-24-16-22-12-8-7-11-21(22)15-23(24)27(33)31-26(28(34)35)20-9-5-4-6-10-20/h7-8,11-16,20,26H,4-6,9-10H2,1-3H3,(H,31,33)(H,34,35)(H2,30,32,36)/t26-/m0/s1
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n/an/a 6n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of human liver glycogen phosphorylase A by fluorescence intensity endpoint assay in presence of glucose


Bioorg Med Chem Lett 19: 976-80 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.085
More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM50149207
PNG
(2N-(2-{2-[2-(5-chloro-1H-2-indolylcarboxamido)etho...)
Show SMILES Clc1ccc2[nH]c(cc2c1)C(=O)NCCOCCOCCNC(=O)c1cc2cc(Cl)ccc2[nH]1
Show InChI InChI=1S/C24H24Cl2N4O4/c25-17-1-3-19-15(11-17)13-21(29-19)23(31)27-5-7-33-9-10-34-8-6-28-24(32)22-14-16-12-18(26)2-4-20(16)30-22/h1-4,11-14,29-30H,5-10H2,(H,27,31)(H,28,32)
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n/an/a 6n/an/an/an/an/an/a



University of Thessaly

Curated by ChEMBL


Assay Description
Inhibition of glycogen phosphorylase a (unknown origin)


Bioorg Med Chem 22: 4810-25 (2014)


Article DOI: 10.1016/j.bmc.2014.06.058
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM39807
PNG
(CP-526,423)
Show SMILES Cc1ccc2[nH]c(cc2c1)C(=O)NCCOCCOCCNC(=O)c1cc2cc(Cl)ccc2[nH]1
Show InChI InChI=1S/C25H27ClN4O4/c1-16-2-4-20-17(12-16)14-22(29-20)24(31)27-6-8-33-10-11-34-9-7-28-25(32)23-15-18-13-19(26)3-5-21(18)30-23/h2-5,12-15,29-30H,6-11H2,1H3,(H,27,31)(H,28,32)
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n/an/a 6n/an/an/an/a7.222



Pfizer Inc



Assay Description
Human liver glycogen phsphorylase (HLGP) activity was measured in the direction of glycogen synthesis by the release of phosphate from glucose-1-phos...


Chem Biol 7: 677-82 (2000)

More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM27726
PNG
((2S,3R)-3-(tert-butoxy)-2-[(3-{[(2,4,6-trimethylph...)
Show SMILES C[C@@H](OC(C)(C)C)[C@H](NC(=O)c1cc2ccccc2cc1NC(=O)Nc1c(C)cc(C)cc1C)C(O)=O |r|
Show InChI InChI=1S/C29H35N3O5/c1-16-12-17(2)24(18(3)13-16)32-28(36)30-23-15-21-11-9-8-10-20(21)14-22(23)26(33)31-25(27(34)35)19(4)37-29(5,6)7/h8-15,19,25H,1-7H3,(H,31,33)(H,34,35)(H2,30,32,36)/t19-,25+/m1/s1
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n/an/a 7n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of human liver glycogen phosphorylase A by fluorescence plate reader assay


Bioorg Med Chem Lett 19: 981-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.084
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM24385
PNG
(2,3-dichloro-N-[1-(2-hydroxyethyl)-2-oxo-1,2,3,4-t...)
Show SMILES OCCN1C(=O)C(Cc2ccccc12)NC(=O)c1cc2sc(Cl)c(Cl)c2[nH]1
Show InChI InChI=1S/C18H15Cl2N3O3S/c19-14-15-13(27-16(14)20)8-10(21-15)17(25)22-11-7-9-3-1-2-4-12(9)23(5-6-24)18(11)26/h1-4,8,11,21,24H,5-7H2,(H,22,25)
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n/an/a 7n/an/an/an/a7.222



AstraZeneca



Assay Description
The inhibitory activity of the test compounds against human recombinant glycogen phosphorylase a (GPa) was monitored using 96-well microplate format....


Bioorg Med Chem Lett 17: 394-9 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.037
More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM27726
PNG
((2S,3R)-3-(tert-butoxy)-2-[(3-{[(2,4,6-trimethylph...)
Show SMILES C[C@@H](OC(C)(C)C)[C@H](NC(=O)c1cc2ccccc2cc1NC(=O)Nc1c(C)cc(C)cc1C)C(O)=O |r|
Show InChI InChI=1S/C29H35N3O5/c1-16-12-17(2)24(18(3)13-16)32-28(36)30-23-15-21-11-9-8-10-20(21)14-22(23)26(33)31-25(27(34)35)19(4)37-29(5,6)7/h8-15,19,25H,1-7H3,(H,31,33)(H,34,35)(H2,30,32,36)/t19-,25+/m1/s1
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n/an/a 7n/an/an/an/a7.625



GSK



Assay Description
An enzymatic assay was developed to measure the response of the activated form of glycogen phosphorylase to small molecule compounds. The assay was t...


Bioorg Med Chem Lett 19: 1177-82 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.085
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM27734
PNG
((2S,3R)-3-(tert-butoxy)-2-{[4-(4-fluorophenyl)-2-{...)
Show SMILES C[C@@H](OC(C)(C)C)[C@H](NC(=O)c1ccc(cc1NC(=O)Nc1c(C)cc(C)cc1C)-c1ccc(F)cc1)C(O)=O |r|
Show InChI InChI=1S/C31H36FN3O5/c1-17-14-18(2)26(19(3)15-17)35-30(39)33-25-16-22(21-8-11-23(32)12-9-21)10-13-24(25)28(36)34-27(29(37)38)20(4)40-31(5,6)7/h8-16,20,27H,1-7H3,(H,34,36)(H,37,38)(H2,33,35,39)/t20-,27+/m1/s1
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n/an/a 7n/an/an/an/a7.625



GSK



Assay Description
An enzymatic assay was developed to measure the response of the activated form of glycogen phosphorylase to small molecule compounds. The assay was t...


Bioorg Med Chem Lett 19: 1177-82 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.085
More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM27744
PNG
((2S,3R)-3-(tert-butoxy)-2-{[4-(3,4-difluorophenyl)...)
Show SMILES CCCc1cc(C)c(NC(=O)Nc2cc(ccc2C(=O)N[C@@H]([C@@H](C)OC(C)(C)C)C(O)=O)-c2ccc(F)c(F)c2)c(C)c1 |r|
Show InChI InChI=1S/C33H39F2N3O5/c1-8-9-21-14-18(2)28(19(3)15-21)38-32(42)36-27-17-23(22-11-13-25(34)26(35)16-22)10-12-24(27)30(39)37-29(31(40)41)20(4)43-33(5,6)7/h10-17,20,29H,8-9H2,1-7H3,(H,37,39)(H,40,41)(H2,36,38,42)/t20-,29+/m1/s1
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n/an/a 7n/an/an/an/a7.625



GSK



Assay Description
An enzymatic assay was developed to measure the response of the activated form of glycogen phosphorylase to small molecule compounds. The assay was t...


Bioorg Med Chem Lett 19: 1177-82 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.085
More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM50133443
PNG
(4-(2-Chloro-phenyl)-1-ethyl-5-isobutylcarbamoyl-6-...)
Show SMILES CCN1C(C)=C(C(C(C(O)=O)=C1C(O)=O)c1ccccc1Cl)C(=O)NCC(C)C |c:4,10|
Show InChI InChI=1S/C21H25ClN2O5/c1-5-24-12(4)15(19(25)23-10-11(2)3)16(13-8-6-7-9-14(13)22)17(20(26)27)18(24)21(28)29/h6-9,11,16H,5,10H2,1-4H3,(H,23,25)(H,26,27)(H,28,29)
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n/an/a 7.88n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human liver glycogen phosphorylase a (HLGPa)


Bioorg Med Chem Lett 13: 3405-8 (2003)

More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM50133431
PNG
(1-(3-Chloro-benzyl)-4-(2-chloro-phenyl)-6-methyl-1...)
Show SMILES CC(C)OC(=O)C1=C(C)N(Cc2cccc(Cl)c2)C(C(O)=O)=C(C1c1ccccc1Cl)C(O)=O |c:6,22|
Show InChI InChI=1S/C25H23Cl2NO6/c1-13(2)34-25(33)19-14(3)28(12-15-7-6-8-16(26)11-15)22(24(31)32)21(23(29)30)20(19)17-9-4-5-10-18(17)27/h4-11,13,20H,12H2,1-3H3,(H,29,30)(H,31,32)
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n/an/a 8n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human liver glycogen phosphorylase a (HLGPa)


Bioorg Med Chem Lett 13: 3405-8 (2003)

More data for this
Ligand-Target Pair
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