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Compile Data Set for Download or QSAR

Found 631 hits Enz. Inhib. hit(s) with Target = 'PRMT5/MEP50 Enzyme'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM343939
PNG
(US9777008, Compound 233)
Show SMILES OC(CNc1cc(ccn1)-c1ncc2ccn(CC(=O)N3CCCC3)c2n1)CN1CCc2ccccc2C1
PDB

UniProtKB/SwissProt

B.MOAD
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PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9777008 (2017)


BindingDB Entry DOI: 10.7270/Q26975QQ
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM343940
PNG
(2-(2-(2-((3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hy...)
Show SMILES OC(CNc1cc(ccn1)-c1ncc2ccn(CC(=O)N3CCOCC3)c2n1)CN1CCc2ccccc2C1
PDB

UniProtKB/SwissProt

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US Patent
n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9777008 (2017)


BindingDB Entry DOI: 10.7270/Q26975QQ
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM343942
PNG
(US9777008, Compound 236)
Show SMILES Cn1cc2ccc(cc2n1)-c1ccnc(NCC(O)CN2CCc3ccccc3C2)c1
PDB

UniProtKB/SwissProt

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US Patent
n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9777008 (2017)


BindingDB Entry DOI: 10.7270/Q26975QQ
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM343944
PNG
(1-(3,4-dihydroisoquinolin-2(1H)-yl)-3-((4-(3-methy...)
Show SMILES Cn1cnc2ccc(nc12)-c1ccnc(NCC(O)CN2CCc3ccccc3C2)c1
PDB

UniProtKB/SwissProt

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US Patent
n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9777008 (2017)


BindingDB Entry DOI: 10.7270/Q26975QQ
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM343945
PNG
(1-(3,4-dihydroisoquinolin-2(1H)-yl)-3-((4-(7-methy...)
Show SMILES Cn1ccc2cnc(nc12)-c1ccnc(NCC(O)CN2CCc3ccccc3C2)c1
PDB

UniProtKB/SwissProt

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US Patent
n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9777008 (2017)


BindingDB Entry DOI: 10.7270/Q26975QQ
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM343946
PNG
(US9777008, Compound 240)
Show SMILES OC(CNc1cc(ccn1)-c1ccc2ncn(C3CCNC3)c2c1)CN1CCc2ccccc2C1
PDB

UniProtKB/SwissProt

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US Patent
n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9777008 (2017)


BindingDB Entry DOI: 10.7270/Q26975QQ
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM343947
PNG
(US9777008, Compound 241)
Show SMILES OC(CNc1cc(ccn1)-c1ccc2ncn(C3CCNCC3)c2c1)CN1CCc2ccccc2C1
PDB

UniProtKB/SwissProt

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US Patent
n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9777008 (2017)


BindingDB Entry DOI: 10.7270/Q26975QQ
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM343951
PNG
(US9777008, Compound 245)
Show SMILES CNC(=O)Cn1ccc2cnc(nc12)-c1ccnc(NCC(O)CN2CCc3ccccc3C2)c1
PDB

UniProtKB/SwissProt

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9777008 (2017)


BindingDB Entry DOI: 10.7270/Q26975QQ
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM343952
PNG
(US9777008, Compound 246)
Show SMILES OC(CNc1cc(ccn1)-c1ncc2ccn(CC(=O)N3CCCCC3)c2n1)CN1CCc2ccccc2C1
PDB

UniProtKB/SwissProt

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US Patent
n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9777008 (2017)


BindingDB Entry DOI: 10.7270/Q26975QQ
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM343953
PNG
(US9777008, Compound 247)
Show SMILES CN1CCN(CC1)C(=O)Cn1ccc2cnc(nc12)-c1ccnc(NCC(O)CN2CCc3ccccc3C2)c1
PDB

UniProtKB/SwissProt

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9777008 (2017)


BindingDB Entry DOI: 10.7270/Q26975QQ
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM343956
PNG
(US9777008, Compound 250)
Show SMILES CN1CCC(C1)n1cnc2ccc(cc12)-c1ccnc(NCC(O)CN2CCc3ccccc3C2)c1
PDB

UniProtKB/SwissProt

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US Patent
n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9777008 (2017)


BindingDB Entry DOI: 10.7270/Q26975QQ
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM343957
PNG
(1-(3,4-dihydroisoquinolin-2(1H)-yl)-3-((4-(1-(tetr...)
Show SMILES OC(CNc1cc(ccn1)-c1ccc2ncn(C3CCOCC3)c2c1)CN1CCc2ccccc2C1
PDB

UniProtKB/SwissProt

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9777008 (2017)


BindingDB Entry DOI: 10.7270/Q26975QQ
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM343958
PNG
(US9777008, Compound 252)
Show SMILES CN1CCC(CC1)n1cnc2ccc(cc12)-c1ccnc(NCC(O)CN2CCc3ccccc3C2)c1
PDB

UniProtKB/SwissProt

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US Patent
n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9777008 (2017)


BindingDB Entry DOI: 10.7270/Q26975QQ
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM343959
PNG
(US9777008, Compound 253)
Show SMILES OC(COc1cccc(c1)-c1ncc2ccn(C3CCNCC3)c2n1)CN1CCc2ccccc2C1
PDB

UniProtKB/SwissProt

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US Patent
n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9777008 (2017)


BindingDB Entry DOI: 10.7270/Q26975QQ
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM343960
PNG
(US9777008, Compound 254)
Show SMILES OC(CNc1cc(ccn1)-c1ncc2ccn(C3CNC3)c2n1)CN1CCc2ccccc2C1
PDB

UniProtKB/SwissProt

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US Patent
n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9777008 (2017)


BindingDB Entry DOI: 10.7270/Q26975QQ
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM343961
PNG
(US9777008, Compound 255)
Show SMILES OC(CNc1cc(ccn1)-c1ncc2ccn(C3CCNCC3)c2n1)CN1CCc2ccccc2C1
PDB

UniProtKB/SwissProt

B.MOAD
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PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9777008 (2017)


BindingDB Entry DOI: 10.7270/Q26975QQ
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM343962
PNG
(US9777008, Compound 256)
Show SMILES CC(=O)N1CCC(CC1)n1ccc2cnc(nc12)-c1ccnc(NCC(O)CN2CCc3ccccc3C2)c1
PDB

UniProtKB/SwissProt

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9777008 (2017)


BindingDB Entry DOI: 10.7270/Q26975QQ
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM343963
PNG
((R)-1-(3,4-dihydroisoquinolin-2(1H)-yl)-3-(3-(quin...)
Show SMILES O[C@@H](COc1cccc(c1)-c1cccc2cccnc12)CN1CCc2ccccc2C1 |r|
PDB

UniProtKB/SwissProt

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US Patent
n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9777008 (2017)


BindingDB Entry DOI: 10.7270/Q26975QQ
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM343967
PNG
(US9777008, Compound 261)
Show SMILES Cn1cc2ccc(nc2n1)-c1cccc(NCC(O)CN2CCc3ccccc3C2)c1
PDB

UniProtKB/SwissProt

B.MOAD
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PC cid
PC sid
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US Patent
n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9777008 (2017)


BindingDB Entry DOI: 10.7270/Q26975QQ
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM343971
PNG
(US9777008, Compound 265)
Show SMILES OC(CNc1cc(ccn1)-c1ccc2ncn(C3COC3)c2c1)CN1CCc2ccccc2C1
PDB

UniProtKB/SwissProt

B.MOAD
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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9777008 (2017)


BindingDB Entry DOI: 10.7270/Q26975QQ
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM343972
PNG
(1-(3,4-dihydroisoquinolin-2(1H)-yl)-3-(3-(3-methyl...)
Show SMILES Cc1ncc2ccc(cn12)-c1cccc(OCC(O)CN2CCc3ccccc3C2)c1
PDB

UniProtKB/SwissProt

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9777008 (2017)


BindingDB Entry DOI: 10.7270/Q26975QQ
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM343975
PNG
(US9777008, Compound 269)
Show SMILES OC(COc1cccc(c1)-c1ccc2ncn(C3COC3)c2c1)CN1CCc2ccccc2C1
PDB

UniProtKB/SwissProt

B.MOAD
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PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9777008 (2017)


BindingDB Entry DOI: 10.7270/Q26975QQ
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM343979
PNG
(N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypr...)
Show SMILES CC(=O)N(CC(O)CN1CCc2ccccc2C1)c1cccc(c1)-c1ccc2ncn(C)c2c1
PDB

UniProtKB/SwissProt

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9777008 (2017)


BindingDB Entry DOI: 10.7270/Q26975QQ
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM343981
PNG
(US9777008, Compound 275)
Show SMILES Cn1cnc2ccc(cc12)-c1ccnc(NC[C@H](O)CN2CCc3ccccc3C2)c1 |r|
PDB

UniProtKB/SwissProt

B.MOAD
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PDB
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PDB
US Patent
n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9777008 (2017)


BindingDB Entry DOI: 10.7270/Q26975QQ
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM343751
PNG
(1-(3,4-dihydroisoquinolin-2(1H)-yl)-3-(3-(1-methyl...)
Show SMILES Cn1cnc2ccc(cc12)-c1cccc(OCC(O)CN2CCc3ccccc3C2)c1
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9777008 (2017)


BindingDB Entry DOI: 10.7270/Q26975QQ
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM343753
PNG
(US9777008, Compound 47)
Show SMILES OC(COc1ccc(cc1)C1CCCNC1)CN1CCc2ccccc2C1
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9777008 (2017)


BindingDB Entry DOI: 10.7270/Q26975QQ
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM343771
PNG
(1-(3,4-dihydroisoquinolin-2(1H)-yl)-3-(3-(quinolin...)
Show SMILES OC(COc1cccc(c1)-c1cccc2cccnc12)CN1CCc2ccccc2C1
PDB

UniProtKB/SwissProt

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9777008 (2017)


BindingDB Entry DOI: 10.7270/Q26975QQ
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM343808
PNG
(1-(3,4-dihydroisoquinolin-2(1H)-yl)-3-((3-(1-methy...)
Show SMILES Cn1cnc2ccc(cc12)-c1cccc(NCC(O)CN2CCc3ccccc3C2)c1
PDB

UniProtKB/SwissProt

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9777008 (2017)


BindingDB Entry DOI: 10.7270/Q26975QQ
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM343811
PNG
(1-(3-(1-benzyl-1H-benzo[d]imidazol-6-yl)phenoxy)-3...)
Show SMILES OC(COc1cccc(c1)-c1ccc2ncn(Cc3ccccc3)c2c1)CN1CCc2ccccc2C1
PDB

UniProtKB/SwissProt

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9777008 (2017)


BindingDB Entry DOI: 10.7270/Q26975QQ
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM343812
PNG
(US9777008, Compound 106)
Show SMILES Cn1ncc2ccc(cc12)-c1cccc(OCC(O)CN2CCc3ccccc3C2)c1
PDB

UniProtKB/SwissProt

B.MOAD
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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9777008 (2017)


BindingDB Entry DOI: 10.7270/Q26975QQ
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM343814
PNG
(US9777008, Compound 108)
Show SMILES Cn1ncc2cc(ccc12)-c1cccc(OCC(O)CN2CCc3ccccc3C2)c1
PDB

UniProtKB/SwissProt

B.MOAD
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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9777008 (2017)


BindingDB Entry DOI: 10.7270/Q26975QQ
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM343822
PNG
(US9777008, Compound 116)
Show SMILES CN(CC(O)CN1CCc2ccccc2C1)c1cccc(CNC2CCOCC2)c1
PDB

UniProtKB/SwissProt

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9777008 (2017)


BindingDB Entry DOI: 10.7270/Q26975QQ
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM343824
PNG
(1-(3,4-Dihydroisoquinolin-2(1H)-yl)-3-((4-(1-methy...)
Show SMILES Cn1cnc2ccc(cc12)-c1ccnc(NCC(O)CN2CCc3ccccc3C2)c1
PDB

UniProtKB/SwissProt

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9777008 (2017)


BindingDB Entry DOI: 10.7270/Q26975QQ
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM343847
PNG
(1-(3,4-dihydroisoquinolin-2(1H)-yl)-3-(3-(7-methyl...)
Show SMILES Cn1ccc2cnc(nc12)-c1cccc(OCC(O)CN2CCc3ccccc3C2)c1
PDB

UniProtKB/SwissProt

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9777008 (2017)


BindingDB Entry DOI: 10.7270/Q26975QQ
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM337109
PNG
(US9745291, Compound 155 | US9765068, Compound 155)
Show SMILES CN(c1ccccc1OCC(=O)NCC(O)CN1CCc2ccccc2C1)S(C)(=O)=O
PDB

UniProtKB/SwissProt

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9745291 (2017)


BindingDB Entry DOI: 10.7270/Q2J1058K
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM337112
PNG
(US9745291, Compound 158 | US9765068, Compound 158)
Show SMILES Cc1nn(C)c2cccc(OCC(=O)NCC(O)CN3CCc4ccccc4C3)c12
PDB

UniProtKB/SwissProt

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9745291 (2017)


BindingDB Entry DOI: 10.7270/Q2J1058K
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM337113
PNG
(US9745291, Compound 159 | US9765068, Compound 159)
Show SMILES Cn1ncc2ccc(OCC(=O)NC[C@H](O)CN3CCc4ccccc4C3)cc12 |r|
PDB

UniProtKB/SwissProt

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9745291 (2017)


BindingDB Entry DOI: 10.7270/Q2J1058K
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM337117
PNG
(US9745291, Compound 163 | US9765068, Compound 163)
Show SMILES Cc1cn(C)c2cccc(OCC(=O)NC[C@H](O)CN3CCc4ccccc4C3)c12 |r|
PDB

UniProtKB/SwissProt

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9745291 (2017)


BindingDB Entry DOI: 10.7270/Q2J1058K
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM337118
PNG
(US9745291, Compound 164 | US9765068, Compound 164)
Show SMILES Cc1cn(C)c2cccc(OCC(=O)NC[C@@H](O)CN3CCc4ccccc4C3)c12 |r|
PDB

UniProtKB/SwissProt

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9745291 (2017)


BindingDB Entry DOI: 10.7270/Q2J1058K
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM337122
PNG
(US9745291, Compound 168 | US9765068, Compound 168)
Show SMILES Nc1ncnc2c(OCC(=O)NCC(O)CN3CCc4ccccc4C3)cccc12
PDB

UniProtKB/SwissProt

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9745291 (2017)


BindingDB Entry DOI: 10.7270/Q2J1058K
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM337123
PNG
(US9745291, Compound 169 | US9765068, Compound 169)
Show SMILES CN(C)c1cccc(OCC(=O)NCC(O)CN2CCc3ccccc3C2)c1S(N)(=O)=O
PDB

UniProtKB/SwissProt

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9745291 (2017)


BindingDB Entry DOI: 10.7270/Q2J1058K
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM337124
PNG
(US9745291, Compound 170 | US9765068, Compound 170)
Show SMILES CC(NC(=O)COc1ccccc1S(N)(=O)=O)C(O)CN1CCc2ccccc2C1
PDB

UniProtKB/SwissProt

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9745291 (2017)


BindingDB Entry DOI: 10.7270/Q2J1058K
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM337129
PNG
(US9745291, Compound 175 | US9745291, Compound 251 ...)
Show SMILES O[C@@H](CNC(=O)CCc1nc2ccccc2[nH]1)CN1CCc2ccccc2C1 |r|
PDB

UniProtKB/SwissProt

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9745291 (2017)


BindingDB Entry DOI: 10.7270/Q2J1058K
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM337135
PNG
(US9745291, Compound 181 | US9765068, Compound 181)
Show SMILES OC(CNC(=O)COc1cccc2cncnc12)CN1CCc2ccccc2C1
PDB

UniProtKB/SwissProt

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9745291 (2017)


BindingDB Entry DOI: 10.7270/Q2J1058K
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM337144
PNG
(US9745291, Compound 190 | US9765068, Compound 190)
Show SMILES CN1CCN(CC1)c1cccc(OCC(=O)NC[C@@H](O)CN2CCc3ccccc3C2)c1 |r|
PDB

UniProtKB/SwissProt

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9745291 (2017)


BindingDB Entry DOI: 10.7270/Q2J1058K
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM337145
PNG
(US9745291, Compound 191 | US9765068, Compound 191)
Show SMILES CN(C)CCN(C)S(=O)(=O)c1ccccc1OCC(=O)NC[C@@H](O)CN1CCc2ccccc2C1 |r|
PDB

UniProtKB/SwissProt

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9745291 (2017)


BindingDB Entry DOI: 10.7270/Q2J1058K
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM337151
PNG
(US9745291, Compound 197)
Show SMILES O[C@H](CNC(=O)COc1cccc(c1)N1CCNCC1)CN1CCc2ccccc2C1 |r|
PDB

UniProtKB/SwissProt

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9745291 (2017)


BindingDB Entry DOI: 10.7270/Q2J1058K
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM337152
PNG
(US9745291, Compound 198)
Show SMILES CN(CCN)S(=O)(=O)c1ccccc1OCC(=O)NC[C@@H](O)CN1CCc2ccccc2C1 |r|
PDB

UniProtKB/SwissProt

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9745291 (2017)


BindingDB Entry DOI: 10.7270/Q2J1058K
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM337155
PNG
(US9745291, Compound 201)
Show SMILES CNCCN(C)S(=O)(=O)c1ccccc1OCC(=O)NC[C@@H](O)CN1CCc2ccccc2C1 |r|
PDB

UniProtKB/SwissProt

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9745291 (2017)


BindingDB Entry DOI: 10.7270/Q2J1058K
More data for this
Ligand-Target Pair
PRMT5/MEP50 Enzyme


(Homo sapiens (Human))
BDBM337156
PNG
(US9745291, Compound 202)
Show SMILES CC1CNCCN1S(=O)(=O)c1ccccc1OCC(=O)NC[C@@H](O)CN1CCc2ccccc2C1 |r|
PDB

UniProtKB/SwissProt

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9745291 (2017)


BindingDB Entry DOI: 10.7270/Q2J1058K
More data for this
Ligand-Target Pair
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