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Compile Data Set for Download or QSAR

Found 439 hits Enz. Inhib. hit(s) with Target = 'PRMT5/MEP50 complex'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM50431676
PNG
(CHEMBL2349526)
Show SMILES N[C@@H](CCSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cc(Br)c2c(N)ncnc12)C(O)=O |r|
Show InChI InChI=1S/C15H20BrN5O5S/c16-6-3-21(13-9(6)12(18)19-5-20-13)14-11(23)10(22)8(26-14)4-27-2-1-7(17)15(24)25/h3,5,7-8,10-11,14,22-23H,1-2,4,17H2,(H,24,25)(H2,18,19,20)/t7-,8+,10+,11+,14+/m0/s1
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1.15E+3n/an/an/an/an/an/an/an/a



EntreMed Inc.

Curated by ChEMBL


Assay Description
Inhibition of PRMT5 (unknown origin) using [3H]SAM after 1 hr by scintillation proximity assay


Bioorg Med Chem 21: 1787-94 (2013)


Article DOI: 10.1016/j.bmc.2013.01.049
BindingDB Entry DOI: 10.7270/Q24F1S41
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM364153
PNG
(US9856252, 45)
PDB

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n/an/a 83n/an/an/an/an/an/a



Bristol-Myers Squibb Company





J Med Chem 49: 2440-55 (2006)

More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM336973
PNG
(US9745291, Compound 19 | US9765068, Compound 19)
Show SMILES CC(Oc1ccccc1)C(=O)NCC(O)CN1CCc2ccccc2C1
PDB

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM336974
PNG
(US9745291, Compound 20 | US9765068, Compound 20)
Show SMILES COc1cccc(OCC(=O)NCC(O)CN2CCc3ccccc3C2)c1
PDB

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM336976
PNG
(US9745291, Compound 22 | US9765068, Compound 22)
Show SMILES COc1ccccc1OCC(=O)NCC(O)CN1CCc2ccccc2C1
PDB

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM336977
PNG
(US9745291, Compound 23 | US9765068, Compound 23)
Show SMILES Cn1ncc2ccc(OCC(=O)NCC(O)CN3CCc4ccccc4C3)cc12
PDB

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM336980
PNG
(US9745291, Compound 26 | US9765068, Compound 26)
Show SMILES Cc1cccc(OCC(=O)NCC(O)CN2CCc3ccccc3C2)c1
PDB

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM336981
PNG
(US9745291, Compound 27 | US9765068, Compound 27)
Show SMILES CN(C)c1cccc(OCC(=O)NCC(O)CN2CCc3ccccc3C2)c1
PDB

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM336982
PNG
(US9745291, Compound 28 | US9765068, Compound 28)
Show SMILES CS(=O)(=O)Nc1cccc(OCC(=O)NCC(O)CN2CCc3ccccc3C2)c1
PDB

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM336991
PNG
(US9745291, Compound 37 | US9765068, Compound 37)
Show SMILES CS(=O)(=O)c1ccccc1OCC(=O)NCC(O)CN1CCc2ccccc2C1
PDB

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM336992
PNG
(US9745291, Compound 38 | US9765068, Compound 38)
Show SMILES CN(C)c1ccccc1OCC(=O)NCC(O)CN1CCc2ccccc2C1
PDB

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM336993
PNG
(US9745291, Compound 39 | US9765068, Compound 39)
Show SMILES CC(Oc1cccc2cccnc12)C(=O)NCC(O)CN1CCc2ccccc2C1
PDB

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM336994
PNG
(US9745291, Compound 40 | US9765068, Compound 40)
Show SMILES OC(CNC(=O)COc1ccccc1C1CCCCC1)CN1CCc2ccccc2C1
PDB

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM336997
PNG
(US9745291, Compound 43 | US9765068, Compound 43)
Show SMILES CC(C)(Oc1cccc2cccnc12)C(=O)NCC(O)CN1CCc2ccccc2C1
PDB

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Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM336999
PNG
(US9745291, Compound 269 | US9745291, Compound 45 |...)
Show SMILES O[C@H](CNC(=O)COc1cccc2cccnc12)CN1CCc2ccccc2C1 |r|
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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM337001
PNG
(US9745291, Compound 47 | US9765068, Compound 47)
Show SMILES CS(=O)(=O)c1cccc(OCC(=O)NCC(O)CN2CCc3ccccc3C2)c1
PDB

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM337002
PNG
(US9745291, Compound 48 | US9765068, Compound 48)
Show SMILES OC(CNC(=O)COc1cccc2ccc(nc12)N1CCOCC1)CN1CCc2ccccc2C1
PDB

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM337003
PNG
(US9745291, Compound 49 | US9765068, Compound 49)
Show SMILES OC(CNC(=O)COc1ccccc1N1CCOCC1)CN1CCc2ccccc2C1
PDB

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM337004
PNG
(US9745291, Compound 50 | US9765068, Compound 50)
Show SMILES OC(CNC(=O)COc1ccccc1-c1cc[nH]n1)CN1CCc2ccccc2C1
PDB

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM337007
PNG
(US9745291, Compound 53 | US9765068, Compound 53)
Show SMILES CS(=O)(=O)Nc1ccccc1OCC(=O)NCC(O)CN1CCc2ccccc2C1
PDB

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM337018
PNG
(US9745291, Compound 64 | US9765068, Compound 64)
Show SMILES OC(CNC(=O)COc1cccc2CCCCc12)CN1CCc2ccccc2C1
PDB

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM337019
PNG
(US9745291, Compound 65 | US9765068, Compound 65)
Show SMILES NS(=O)(=O)c1ccccc1OCC(=O)NCC(O)CN1CCc2ccccc2C1
PDB

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM337020
PNG
(US9745291, Compound 66 | US9765068, Compound 66)
Show SMILES OC(CNC(=O)COc1cccc2ccccc12)CN1CCc2ccccc2C1
PDB

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM337021
PNG
(US9745291, Compound 67 | US9765068, Compound 67)
Show SMILES O[C@H](CNC(=O)COc1ccccc1-c1cc[nH]n1)CN1CCc2ccccc2C1 |r|
PDB

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM337022
PNG
(US9745291, Compound 68 | US9765068, Compound 68)
Show SMILES O[C@@H](CNC(=O)COc1ccccc1-c1cc[nH]n1)CN1CCc2ccccc2C1 |r|
PDB

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM337024
PNG
(US9745291, Compound 70 | US9765068, Compound 70)
Show SMILES OC(CNC(=O)COc1ccc2cnn(C3CCNCC3)c2c1)CN1CCc2ccccc2C1
PDB

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM337025
PNG
(US9745291, Compound 71 | US9765068, Compound 71)
Show SMILES CN1CCC(CC1)n1ncc2ccc(OCC(=O)NCC(O)CN3CCc4ccccc4C3)cc12
PDB

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM337052
PNG
(US9745291, Compound 98 | US9765068, Compound 98)
Show SMILES COc1ccc2cccc(OCC(=O)NC[C@@H](O)CN3CCc4ccccc4C3)c2n1 |r|
PDB

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM337053
PNG
(US9745291, Compound 99 | US9765068, Compound 99)
Show SMILES CN1CCc2c(C1)cccc2OCC(=O)NCC(O)CN1CCc2ccccc2C1
PDB

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM337054
PNG
(US9745291, Compound 100 | US9765068, Compound 100)
Show SMILES OC(CNC(=O)COc1cccc2OCCOc12)CN1CCc2ccccc2C1
PDB

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM337055
PNG
(US9745291, Compound 101 | US9765068, Compound 101)
Show SMILES CC(=O)N1CCc2c(C1)cccc2OCC(=O)NCC(O)CN1CCc2ccccc2C1
PDB

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM337056
PNG
(US9745291, Compound 102 | US9765068, Compound 102)
Show SMILES CS(=O)(=O)N1CCc2c(C1)cccc2OCC(=O)NCC(O)CN1CCc2ccccc2C1
PDB

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM337057
PNG
(US9745291, Compound 103 | US9765068, Compound 103)
Show SMILES OC(CNC(=O)COc1ccccc1C1CCNCC1)CN1CCc2ccccc2C1
PDB

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM337059
PNG
(US9745291, Compound 105 | US9765068, Compound 105)
Show SMILES CN(C)c1ccc2cccc(OCC(=O)NC[C@@H](O)CN3CCc4ccccc4C3)c2n1 |r|
PDB

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM337061
PNG
(US9745291, Compound 107 | US9765068, Compound 107)
Show SMILES OC(CNC(=O)COc1ccccc1S(=O)(=O)N1CCNCC1)CN1CCc2ccccc2C1
PDB

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM337062
PNG
(US9745291, Compound 108 | US9765068, Compound 108)
Show SMILES CN1CCN(CC1)S(=O)(=O)c1ccccc1OCC(=O)NCC(O)CN1CCc2ccccc2C1
PDB

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM337063
PNG
(US9745291, Compound 109 | US9765068, Compound 109)
Show SMILES CN(C)S(=O)(=O)c1ccccc1OCC(=O)NCC(O)CN1CCc2ccccc2C1
PDB

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Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM337064
PNG
(US9745291, Compound 110 | US9765068, Compound 110)
Show SMILES OC(CNC(=O)COc1ccccc1S(=O)(=O)N1CCCC1)CN1CCc2ccccc2C1
PDB

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Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM337065
PNG
(US9745291, Compound 111 | US9765068, Compound 111)
Show SMILES OC(CNC(=O)COc1ccccc1S(=O)(=O)N1CCC(O)C1)CN1CCc2ccccc2C1
PDB

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Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM337073
PNG
(US9745291, Compound 119 | US9765068, Compound 119)
Show SMILES OC(CNC(=O)COc1cccc2CCNCc12)CN1CCc2ccccc2C1
PDB

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Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM337077
PNG
(US9745291, Compound 123 | US9765068, Compound 123)
Show SMILES CNS(=O)(=O)c1ccccc1OCC(=O)NCC(O)CN1CCc2ccccc2C1
PDB

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Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM337084
PNG
(US9745291, Compound 130 | US9765068, Compound 130)
Show SMILES CN1CCCC(C1)c1ccccc1OCC(=O)NCC(O)CN1CCc2ccccc2C1
PDB

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Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM337100
PNG
(US9745291, Compound 146 | US9765068, Compound 146)
Show SMILES Cc1cn(C)c2cccc(OCC(=O)NCC(O)CN3CCc4ccccc4C3)c12
PDB

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Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM337103
PNG
(US9745291, Compound 149 | US9765068, Compound 149)
Show SMILES OC(CNC(=O)COc1ccccc1S(=O)(=O)N1CCOCC1)CN1CCc2ccccc2C1
PDB

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Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM337107
PNG
(US9745291, Compound 153 | US9765068, Compound 153)
Show SMILES Cn1cnc(c1)-c1ccccc1OCC(=O)NCC(O)CN1CCc2ccccc2C1
PDB

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Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM337109
PNG
(US9745291, Compound 155 | US9765068, Compound 155)
Show SMILES CN(c1ccccc1OCC(=O)NCC(O)CN1CCc2ccccc2C1)S(C)(=O)=O
PDB

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Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM337112
PNG
(US9745291, Compound 158 | US9765068, Compound 158)
Show SMILES Cc1nn(C)c2cccc(OCC(=O)NCC(O)CN3CCc4ccccc4C3)c12
PDB

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Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM337113
PNG
(US9745291, Compound 159 | US9765068, Compound 159)
Show SMILES Cn1ncc2ccc(OCC(=O)NC[C@H](O)CN3CCc4ccccc4C3)cc12 |r|
PDB

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Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM337117
PNG
(US9745291, Compound 163 | US9765068, Compound 163)
Show SMILES Cc1cn(C)c2cccc(OCC(=O)NC[C@H](O)CN3CCc4ccccc4C3)c12 |r|
PDB

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Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))
BDBM337118
PNG
(US9745291, Compound 164 | US9765068, Compound 164)
Show SMILES Cc1cn(C)c2cccc(OCC(=O)NC[C@@H](O)CN3CCc4ccccc4C3)c12 |r|
PDB

UniProtKB/SwissProt

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n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent




US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair
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