Found 114 hits Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50333221
 (6-(pyridin-4-yl)benzo[d]thiazol-2-amine | CHEMBL16...)Show InChI InChI=1S/C12H9N3S/c13-12-15-10-2-1-9(7-11(10)16-12)8-3-5-14-6-4-8/h1-7H,(H2,13,15) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | 2.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50107268
 (CHEMBL3600693)Show InChI InChI=1S/C13H11N3O2S2/c1-20(17,18)12-5-3-9(7-15-12)8-2-4-10-11(6-8)19-13(14)16-10/h2-7H,1H3,(H2,14,16) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50106970
 (CHEMBL3600767)Show InChI InChI=1S/C12H9N3OS/c13-12-15-9-2-1-7(5-10(9)17-12)8-3-4-14-11(16)6-8/h1-6H,(H2,13,15)(H,14,16) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | 1.58E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50333219
 (6-(6-methoxypyridin-3-yl)benzo[d]thiazol-2-amine |...)Show InChI InChI=1S/C13H11N3OS/c1-17-12-5-3-9(7-15-12)8-2-4-10-11(6-8)18-13(14)16-10/h2-7H,1H3,(H2,14,16) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | 2.51E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50107255
 (CHEMBL3600783)Show SMILES C[C@H](Nc1nc2ccc(cc2s1)-c1ccn(CC2CC2)c(=O)c1)C1CCOCC1 |r| Show InChI InChI=1/C23H27N3O2S/c1-15(17-7-10-28-11-8-17)24-23-25-20-5-4-18(12-21(20)29-23)19-6-9-26(22(27)13-19)14-16-2-3-16/h4-6,9,12-13,15-17H,2-3,7-8,10-11,14H2,1H3,(H,24,25)/t15-/s2 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | 2.51E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50107015
 (CHEMBL3600772)Show InChI InChI=1S/C13H14N4S/c1-2-5-17-8-10(7-15-17)9-3-4-11-12(6-9)18-13(14)16-11/h3-4,6-8H,2,5H2,1H3,(H2,14,16) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | 2.51E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50107264
 (CHEMBL3600688)Show InChI InChI=1S/C14H14N4S/c1-2-16-13-6-4-10(8-17-13)9-3-5-11-12(7-9)19-14(15)18-11/h3-8H,2H2,1H3,(H2,15,18)(H,16,17) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | 3.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50106927
 (CHEMBL3600702)Show InChI InChI=1S/C11H8N4S/c12-11-15-8-3-2-7(6-9(8)16-11)10-13-4-1-5-14-10/h1-6H,(H2,12,15) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
Patents
| PubMed
| n/a | n/a | 3.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50107276
 (CHEMBL3600696)Show InChI InChI=1S/C14H12N4OS/c1-16-13(19)11-5-3-9(7-17-11)8-2-4-10-12(6-8)20-14(15)18-10/h2-7H,1H3,(H2,15,18)(H,16,19) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | 3.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50106926
 (CHEMBL3600701)Show InChI InChI=1S/C12H9N3S/c13-12-15-10-4-3-8(6-11(10)16-12)9-2-1-5-14-7-9/h1-7H,(H2,13,15) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | 3.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50107272
 (CHEMBL3600698)Show InChI InChI=1S/C15H15N3OS/c1-9(2)19-12-5-11(7-17-8-12)10-3-4-13-14(6-10)20-15(16)18-13/h3-9H,1-2H3,(H2,16,18) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | 3.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50106969
 (CHEMBL3600766)Show InChI InChI=1S/C12H9N3OS/c13-12-15-9-3-1-7(5-10(9)17-12)8-2-4-11(16)14-6-8/h1-6H,(H2,13,15)(H,14,16) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | 3.98E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50107016
 (CHEMBL3600773)Show InChI InChI=1S/C13H14N4S/c1-8(2)17-7-10(6-15-17)9-3-4-11-12(5-9)18-13(14)16-11/h3-8H,1-2H3,(H2,14,16) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | 6.31E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50107011
 (CHEMBL3600768)Show InChI InChI=1S/C11H10N4S/c1-15-5-4-8(14-15)7-2-3-9-10(6-7)16-11(12)13-9/h2-6H,1H3,(H2,12,13) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | 6.31E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50107243
 (CHEMBL3600779)Show InChI InChI=1S/C16H15N3OS/c17-16-18-13-4-3-11(7-14(13)21-16)12-5-6-19(15(20)8-12)9-10-1-2-10/h3-8,10H,1-2,9H2,(H2,17,18) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | <7.94E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50107277
 (CHEMBL97245)Show InChI InChI=1S/C13H10N2S/c14-13-15-11-7-6-10(8-12(11)16-13)9-4-2-1-3-5-9/h1-8H,(H2,14,15) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| Purchase
CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | <1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50107274
 (CHEMBL3600700)Show InChI InChI=1S/C12H9N3S/c13-12-15-10-5-4-8(7-11(10)16-12)9-3-1-2-6-14-9/h1-7H,(H2,13,15) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | <1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50107256
 (CHEMBL3600784)Show SMILES O=c1cc(ccn1CC1CC1)-c1ccc2nc(NCC3CCS(=O)(=O)CC3)sc2c1 Show InChI InChI=1S/C22H25N3O3S2/c26-21-12-18(5-8-25(21)14-16-1-2-16)17-3-4-19-20(11-17)29-22(24-19)23-13-15-6-9-30(27,28)10-7-15/h3-5,8,11-12,15-16H,1-2,6-7,9-10,13-14H2,(H,23,24) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | <1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50106928
 (CHEMBL3600765)Show InChI InChI=1S/C11H8N4S/c12-11-15-8-2-1-7(5-10(8)16-11)9-6-13-3-4-14-9/h1-6H,(H2,12,15) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | <1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50107258
 (CHEMBL3600683)Show InChI InChI=1S/C14H13N3OS/c1-2-18-13-6-4-10(8-16-13)9-3-5-11-12(7-9)19-14(15)17-11/h3-8H,2H2,1H3,(H2,15,17) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | <1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50107012
 (CHEMBL3600769)Show InChI InChI=1S/C11H10N4S/c1-15-9(4-5-13-15)7-2-3-8-10(6-7)16-11(12)14-8/h2-6H,1H3,(H2,12,14) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | <1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50107013
 (CHEMBL3600770)Show InChI InChI=1S/C11H10N4S/c1-15-6-8(5-13-15)7-2-3-9-10(4-7)16-11(12)14-9/h2-6H,1H3,(H2,12,14) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| Purchase
CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | <1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50107014
 (CHEMBL3600771)Show InChI InChI=1S/C12H12N4S/c1-2-16-7-9(6-14-16)8-3-4-10-11(5-8)17-12(13)15-10/h3-7H,2H2,1H3,(H2,13,15) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | <1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50107254
 (CHEMBL3600782)Show SMILES C[C@@H](Nc1nc2ccc(cc2s1)-c1ccn(CC2CC2)c(=O)c1)C1CCOCC1 |r| Show InChI InChI=1/C23H27N3O2S/c1-15(17-7-10-28-11-8-17)24-23-25-20-5-4-18(12-21(20)29-23)19-6-9-26(22(27)13-19)14-16-2-3-16/h4-6,9,12-13,15-17H,2-3,7-8,10-11,14H2,1H3,(H,24,25)/t15-/s2 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | <1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50107091
 (CHEMBL3600774)Show InChI InChI=1S/C13H12N4S/c14-13-16-11-4-1-8(5-12(11)18-13)9-6-15-17(7-9)10-2-3-10/h1,4-7,10H,2-3H2,(H2,14,16) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | <1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50107238
 (CHEMBL3600776)Show InChI InChI=1S/C17H14N4S/c18-17-20-15-7-6-13(8-16(15)22-17)14-9-19-21(11-14)10-12-4-2-1-3-5-12/h1-9,11H,10H2,(H2,18,20) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | <1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50107241
 (CHEMBL3600777)Show InChI InChI=1S/C13H11N3OS/c1-16-5-4-9(7-12(16)17)8-2-3-10-11(6-8)18-13(14)15-10/h2-7H,1H3,(H2,14,15) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | <1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50107242
 (CHEMBL3600778)Show InChI InChI=1S/C14H13N3OS/c1-2-17-6-5-10(8-13(17)18)9-3-4-11-12(7-9)19-14(15)16-11/h3-8H,2H2,1H3,(H2,15,16) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | <1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50107244
 (CHEMBL3600780)Show InChI InChI=1S/C15H15N3O3S/c1-20-6-7-21-18-5-4-11(9-14(18)19)10-2-3-12-13(8-10)22-15(16)17-12/h2-5,8-9H,6-7H2,1H3,(H2,16,17) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | <1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50107248
 (CHEMBL3600781)Show SMILES O=c1cc(ccn1CC1CC1)-c1ccc2nc(NCC3CCOCC3)sc2c1 Show InChI InChI=1S/C22H25N3O2S/c26-21-12-18(5-8-25(21)14-16-1-2-16)17-3-4-19-20(11-17)28-22(24-19)23-13-15-6-9-27-10-7-15/h3-5,8,11-12,15-16H,1-2,6-7,9-10,13-14H2,(H,23,24) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | <1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50107263
 (CHEMBL3600687)Show InChI InChI=1S/C15H15N3OS/c1-9(2)19-14-6-4-11(8-17-14)10-3-5-12-13(7-10)20-15(16)18-12/h3-9H,1-2H3,(H2,16,18) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | <1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50107262
 (CHEMBL3600686)Show InChI InChI=1S/C14H14N4S/c1-16-8-11-4-2-10(7-17-11)9-3-5-12-13(6-9)19-14(15)18-12/h2-7,16H,8H2,1H3,(H2,15,18) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | <1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50107273
 (CHEMBL3600699)Show InChI InChI=1S/C13H11N3O2S2/c1-20(17,18)10-4-9(6-15-7-10)8-2-3-11-12(5-8)19-13(14)16-11/h2-7H,1H3,(H2,14,16) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | <1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50107271
 (CHEMBL3600697)Show InChI InChI=1S/C15H14N4OS/c1-19(2)14(20)12-6-4-10(8-17-12)9-3-5-11-13(7-9)21-15(16)18-11/h3-8H,1-2H3,(H2,16,18) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | <1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50107270
 (CHEMBL3600695)Show InChI InChI=1S/C15H15N3O2S/c1-19-6-7-20-14-5-3-11(9-17-14)10-2-4-12-13(8-10)21-15(16)18-12/h2-5,8-9H,6-7H2,1H3,(H2,16,18) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | <1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50107269
 (CHEMBL3600694)Show InChI InChI=1S/C14H13N3O2S/c15-14-17-11-3-1-9(7-12(11)20-14)10-2-4-13(16-8-10)19-6-5-18/h1-4,7-8,18H,5-6H2,(H2,15,17) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | <1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50107260
 (CHEMBL3600684)Show InChI InChI=1S/C14H13N3S2/c1-2-18-13-6-4-10(8-16-13)9-3-5-11-12(7-9)19-14(15)17-11/h3-8H,2H2,1H3,(H2,15,17) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | <1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50107267
 (CHEMBL3600692)Show InChI InChI=1S/C13H8F3N3S/c14-13(15,16)11-4-2-8(6-18-11)7-1-3-9-10(5-7)20-12(17)19-9/h1-6H,(H2,17,19) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
Patents
| PubMed
| n/a | n/a | <1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50107266
 (CHEMBL3600691)Show InChI InChI=1S/C13H11N3S/c1-8-2-3-10(7-15-8)9-4-5-11-12(6-9)17-13(14)16-11/h2-7H,1H3,(H2,14,16) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | <1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50107275
 (CHEMBL3600690)Show InChI InChI=1S/C13H11N3OS/c14-13-16-11-4-2-8(5-12(11)18-13)9-1-3-10(7-17)15-6-9/h1-6,17H,7H2,(H2,14,16) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | <1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50107261
 (CHEMBL3600685)Show InChI InChI=1S/C14H13N3OS/c1-18-8-11-4-2-10(7-16-11)9-3-5-12-13(6-9)19-14(15)17-12/h2-7H,8H2,1H3,(H2,15,17) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
Patents
| PubMed
| n/a | n/a | <1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50107265
 (CHEMBL3600689)Show InChI InChI=1S/C15H16N4S/c1-3-19(2)14-7-5-11(9-17-14)10-4-6-12-13(8-10)20-15(16)18-12/h4-9H,3H2,1-2H3,(H2,16,18) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
| PubMed
| n/a | n/a | <1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50026612
 (BIBF-1120 | NINTEDANIB | Nintedanib | Vargatef)Show SMILES COC(=O)c1ccc2\C(=C(\Nc3ccc(cc3)N(C)C(=O)CN3CCN(C)CC3)c3ccccc3)C(=O)Nc2c1 Show InChI InChI=1S/C31H33N5O4/c1-34-15-17-36(18-16-34)20-27(37)35(2)24-12-10-23(11-13-24)32-29(21-7-5-4-6-8-21)28-25-14-9-22(31(39)40-3)19-26(25)33-30(28)38/h4-14,19,32H,15-18,20H2,1-3H3,(H,33,38)/b29-28- | Reactome pathway KEGG
UniProtKB/SwissProt
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PC cid PC sid PDB UniChem
| Article PubMed
| n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences
Curated by ChEMBL
| Assay Description Binding constant for PIP5K1C kinase domain |
Nat Biotechnol 29: 1046-51 (2011)
Article DOI: 10.1038/nbt.1990 BindingDB Entry DOI: 10.7270/Q25D8S70 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50308060
 (16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,1...)Show SMILES C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4C(=O)NCc4c4c5ccccc5n2c4c13 |r| Show InChI InChI=1S/C26H21N3O4/c1-25-26(32,12-30)10-18(33-25)28-16-8-4-2-6-13(16)20-21-15(11-27-24(21)31)19-14-7-3-5-9-17(14)29(25)23(19)22(20)28/h2-9,18,30,32H,10-12H2,1H3,(H,27,31)/t18-,25+,26+/m1/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences
Curated by ChEMBL
| Assay Description Binding constant for PIP5K1C kinase domain |
Nat Biotechnol 29: 1046-51 (2011)
Article DOI: 10.1038/nbt.1990 BindingDB Entry DOI: 10.7270/Q25D8S70 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM2579
 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)Show SMILES CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 |r| Show InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL KEGG MMDB PC cid PC sid PDB UniChem
Patents
| Article PubMed
| n/a | n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences
Curated by ChEMBL
| Assay Description Binding constant for PIP5K1C kinase domain |
Nat Biotechnol 29: 1046-51 (2011)
Article DOI: 10.1038/nbt.1990 BindingDB Entry DOI: 10.7270/Q25D8S70 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50326053
 (CHEMBL608533 | PKC-412)Show SMILES CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)c1ccccc1 |r| Show InChI InChI=1S/C35H30N4O4/c1-35-32(42-3)25(37(2)34(41)19-11-5-4-6-12-19)17-26(43-35)38-23-15-9-7-13-20(23)28-29-22(18-36-33(29)40)27-21-14-8-10-16-24(21)39(35)31(27)30(28)38/h4-16,25-26,32H,17-18H2,1-3H3,(H,36,40)/t25-,26-,32-,35+/m1/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL PC cid PC sid PDB UniChem
Patents
| Article PubMed
| n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences
Curated by ChEMBL
| Assay Description Binding constant for PIP5K1C kinase domain |
Nat Biotechnol 29: 1046-51 (2011)
Article DOI: 10.1038/nbt.1990 BindingDB Entry DOI: 10.7270/Q25D8S70 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM25045
 (3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin...)Show InChI InChI=1S/C19H16N4O3/c24-13-4-1-3-12(11-13)17-21-15-14-5-2-6-20-19(14)26-16(15)18(22-17)23-7-9-25-10-8-23/h1-6,11,24H,7-10H2 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
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CHEMBL MMDB PC cid PC sid PDB UniChem
Patents
| Article PubMed
| n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences
Curated by ChEMBL
| Assay Description Binding constant for PIP5K1C kinase domain |
Nat Biotechnol 29: 1046-51 (2011)
Article DOI: 10.1038/nbt.1990 BindingDB Entry DOI: 10.7270/Q25D8S70 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50237710
 (4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifl...)Show SMILES Cc1cn(cn1)-c1cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)cc(c1)C(F)(F)F Show InChI InChI=1S/C28H22F3N7O/c1-17-5-6-19(10-25(17)37-27-33-9-7-24(36-27)20-4-3-8-32-14-20)26(39)35-22-11-21(28(29,30)31)12-23(13-22)38-15-18(2)34-16-38/h3-16H,1-2H3,(H,35,39)(H,33,36,37) | Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem
Patents
| Article PubMed
| n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences
Curated by ChEMBL
| Assay Description Binding constant for PIP5K1C kinase domain |
Nat Biotechnol 29: 1046-51 (2011)
Article DOI: 10.1038/nbt.1990 BindingDB Entry DOI: 10.7270/Q25D8S70 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM31095
 (5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)Show SMILES Cc1[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1 Show InChI InChI=1S/C23H27FN4O4/c1-13-20(10-18-17-9-15(24)3-4-19(17)27-22(18)30)26-14(2)21(13)23(31)25-11-16(29)12-28-5-7-32-8-6-28/h3-4,9-10,16,26,29H,5-8,11-12H2,1-2H3,(H,25,31)(H,27,30)/b18-10-/t16-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| Purchase
PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences
Curated by ChEMBL
| Assay Description Binding constant for PIP5K1C kinase domain |
Nat Biotechnol 29: 1046-51 (2011)
Article DOI: 10.1038/nbt.1990 BindingDB Entry DOI: 10.7270/Q25D8S70 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM60665
 (BDBM50249542 | US9145414, R406 | US9212178, R406)Show SMILES COc1cc(Nc2ncc(F)c(Nc3ccc4OC(C)(C)C(=O)Nc4n3)n2)cc(OC)c1OC Show InChI InChI=1S/C22H23FN6O5/c1-22(2)20(30)28-19-13(34-22)6-7-16(27-19)26-18-12(23)10-24-21(29-18)25-11-8-14(31-3)17(33-5)15(9-11)32-4/h6-10H,1-5H3,(H3,24,25,26,27,28,29,30) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| Purchase
DrugBank PC cid PC sid PDB UniChem
| Article PubMed
| n/a | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences
Curated by ChEMBL
| Assay Description Binding constant for PIP5K1C kinase domain |
Nat Biotechnol 29: 1046-51 (2011)
Article DOI: 10.1038/nbt.1990 BindingDB Entry DOI: 10.7270/Q25D8S70 |
More data for this Ligand-Target Pair | |