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Compile Data Set for Download or QSAR

Found 79 hits Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase 14'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Poly [ADP-ribose] polymerase 14


(Homo sapiens)
CHEMBL4068366
PNG
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 160n/an/an/an/an/an/a



McDaniel College

Curated by ChEMBL




Bioorg Med Chem Lett 27: 2907-2911 (2017)


Article DOI: 10.1016/j.bmcl.2017.04.089
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 14


(Homo sapiens)
CHEMBL4074448
PNG
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 270n/an/an/an/an/an/a



McDaniel College

Curated by ChEMBL




Bioorg Med Chem Lett 27: 2907-2911 (2017)


Article DOI: 10.1016/j.bmcl.2017.04.089
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 14


(Homo sapiens)
CHEMBL4074448
PNG
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 275n/an/an/an/an/an/a



McDaniel College

Curated by ChEMBL




Bioorg Med Chem Lett 27: 2907-2911 (2017)


Article DOI: 10.1016/j.bmcl.2017.04.089
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 14


(Homo sapiens)
CHEMBL4104938
PNG
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 370n/an/an/an/an/an/a



McDaniel College

Curated by ChEMBL




Bioorg Med Chem Lett 27: 2907-2911 (2017)


Article DOI: 10.1016/j.bmcl.2017.04.089
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 14


(Homo sapiens)
CHEMBL4104938
PNG
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 372n/an/an/an/an/an/a



McDaniel College

Curated by ChEMBL




Bioorg Med Chem Lett 27: 2907-2911 (2017)


Article DOI: 10.1016/j.bmcl.2017.04.089
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 14


(Homo sapiens)
CHEMBL4079213
PNG
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 407n/an/an/an/an/an/a



McDaniel College

Curated by ChEMBL




Bioorg Med Chem Lett 27: 2907-2911 (2017)


Article DOI: 10.1016/j.bmcl.2017.04.089
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 14


(Homo sapiens)
CHEMBL4084742
PNG
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 407n/an/an/an/an/an/a



McDaniel College

Curated by ChEMBL




Bioorg Med Chem Lett 27: 2907-2911 (2017)


Article DOI: 10.1016/j.bmcl.2017.04.089
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 14


(Homo sapiens)
CHEMBL4079213
PNG
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 410n/an/an/an/an/an/a



McDaniel College

Curated by ChEMBL




Bioorg Med Chem Lett 27: 2907-2911 (2017)


Article DOI: 10.1016/j.bmcl.2017.04.089
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 14


(Homo sapiens)
CHEMBL4104503
PNG
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 447n/an/an/an/an/an/a



McDaniel College

Curated by ChEMBL




Bioorg Med Chem Lett 27: 2907-2911 (2017)


Article DOI: 10.1016/j.bmcl.2017.04.089
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 14


(Homo sapiens)
CHEMBL4104503
PNG
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 450n/an/an/an/an/an/a



McDaniel College

Curated by ChEMBL




Bioorg Med Chem Lett 27: 2907-2911 (2017)


Article DOI: 10.1016/j.bmcl.2017.04.089
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 14


(Homo sapiens)
CHEMBL4068366
PNG
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 617n/an/an/an/an/an/a



McDaniel College

Curated by ChEMBL




Bioorg Med Chem Lett 27: 2907-2911 (2017)


Article DOI: 10.1016/j.bmcl.2017.04.089
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 14


(Homo sapiens)
CHEMBL4080281
PNG
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 650n/an/an/an/an/an/a



McDaniel College

Curated by ChEMBL




Bioorg Med Chem Lett 27: 2907-2911 (2017)


Article DOI: 10.1016/j.bmcl.2017.04.089
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 14


(Homo sapiens)
CHEMBL4080281
PNG
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 676n/an/an/an/an/an/a



McDaniel College

Curated by ChEMBL




Bioorg Med Chem Lett 27: 2907-2911 (2017)


Article DOI: 10.1016/j.bmcl.2017.04.089
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 14


(Homo sapiens)
CHEMBL4085694
PNG
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 690n/an/an/an/an/an/a



McDaniel College

Curated by ChEMBL




Bioorg Med Chem Lett 27: 2907-2911 (2017)


Article DOI: 10.1016/j.bmcl.2017.04.089
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 14


(Homo sapiens)
CHEMBL4085694
PNG
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 692n/an/an/an/an/an/a



McDaniel College

Curated by ChEMBL




Bioorg Med Chem Lett 27: 2907-2911 (2017)


Article DOI: 10.1016/j.bmcl.2017.04.089
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 14


(Homo sapiens)
CHEMBL4089522
PNG
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 700n/an/an/an/an/an/a



McDaniel College

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](+)-NAN binding to haloperidol-sensitive sigma binding site in whole guinea pig brain


Bioorg Med Chem Lett 27: 2907-2911 (2017)


Article DOI: 10.1016/j.bmcl.2017.04.089
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 14


(Homo sapiens)
CHEMBL4089522
PNG
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 708n/an/an/an/an/an/a



McDaniel College

Curated by ChEMBL




Bioorg Med Chem Lett 27: 2907-2911 (2017)


Article DOI: 10.1016/j.bmcl.2017.04.089
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 14


(Homo sapiens)
CHEMBL4087082
PNG
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 891n/an/an/an/an/an/a



McDaniel College

Curated by ChEMBL




Bioorg Med Chem Lett 27: 2907-2911 (2017)


Article DOI: 10.1016/j.bmcl.2017.04.089
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 14


(Homo sapiens)
CHEMBL4087082
PNG
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 900n/an/an/an/an/an/a



McDaniel College

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H](+)-NAN binding to haloperidol-sensitive sigma binding site in whole guinea pig brain


Bioorg Med Chem Lett 27: 2907-2911 (2017)


Article DOI: 10.1016/j.bmcl.2017.04.089
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 14


(Homo sapiens)
CHEMBL4103623
PNG
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 1.02E+3n/an/an/an/an/an/a



McDaniel College

Curated by ChEMBL




Bioorg Med Chem Lett 27: 2907-2911 (2017)


Article DOI: 10.1016/j.bmcl.2017.04.089
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 14


(Homo sapiens)
CHEMBL4101019
PNG
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.07E+3n/an/an/an/an/an/a



McDaniel College

Curated by ChEMBL




Bioorg Med Chem Lett 27: 2907-2911 (2017)


Article DOI: 10.1016/j.bmcl.2017.04.089
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 14


(Homo sapiens)
CHEMBL4101019
PNG
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.10E+3n/an/an/an/an/an/a



McDaniel College

Curated by ChEMBL




Bioorg Med Chem Lett 27: 2907-2911 (2017)


Article DOI: 10.1016/j.bmcl.2017.04.089
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 14


(Homo sapiens)
CHEMBL4103623
PNG
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 1.40E+3n/an/an/an/an/an/a



McDaniel College

Curated by ChEMBL




Bioorg Med Chem Lett 27: 2907-2911 (2017)


Article DOI: 10.1016/j.bmcl.2017.04.089
More data for this
Ligand-Target Pair
Human diphtheria toxin-like ADP-ribosyltransferase (ARTD8 or PARP14)


(Homo sapiens (Human))
BDBM50079620
PNG
(CHEMBL3414775)
Show SMILES COC(=O)\C=C/C(=O)Nc1cccc(c1)C(N)=O
Show InChI InChI=1S/C12H12N2O4/c1-18-11(16)6-5-10(15)14-9-4-2-3-8(7-9)12(13)17/h2-7H,1H3,(H2,13,17)(H,14,15)/b6-5-
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.60E+3n/an/an/an/an/an/a



Karolinska Institutet

Curated by ChEMBL


Assay Description
Inhibition of hexahistidine-tagged human recombinant ARTD8 catalytic domain (1611 to 1801 amino acids) expressed in Escherichia coli BL21(DE3) assess...


Eur J Med Chem 95: 546-51 (2015)


Article DOI: 10.1016/j.ejmech.2015.03.067
More data for this
Ligand-Target Pair
Human diphtheria toxin-like ADP-ribosyltransferase (ARTD8 or PARP14)


(Homo sapiens (Human))
BDBM50079620
PNG
(CHEMBL3414775)
Show SMILES COC(=O)\C=C/C(=O)Nc1cccc(c1)C(N)=O
Show InChI InChI=1S/C12H12N2O4/c1-18-11(16)6-5-10(15)14-9-4-2-3-8(7-9)12(13)17/h2-7H,1H3,(H2,13,17)(H,14,15)/b6-5-
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.66E+3n/an/an/an/an/an/a



Karolinska Institutet

Curated by ChEMBL


Assay Description
Inhibition of hexahistidine-tagged human recombinant ARTD8 catalytic domain (1611 to 1801 amino acids) expressed in Escherichia coli BL21(DE3) assess...


Eur J Med Chem 95: 546-51 (2015)


Article DOI: 10.1016/j.ejmech.2015.03.067
More data for this
Ligand-Target Pair
Human diphtheria toxin-like ADP-ribosyltransferase (ARTD8 or PARP14)


(Homo sapiens (Human))
BDBM50316226
PNG
((S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-car...)
Show SMILES NC(=O)c1cccc2cn(nc12)-c1ccc(cc1)[C@@H]1CCCNC1 |r|
Show InChI InChI=1S/C19H20N4O/c20-19(24)17-5-1-3-15-12-23(22-18(15)17)16-8-6-13(7-9-16)14-4-2-10-21-11-14/h1,3,5-9,12,14,21H,2,4,10-11H2,(H2,20,24)/t14-/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
PDB
UniChem

Patents

n/an/a 1.74E+3n/an/an/an/an/an/a



Health& Science University

Curated by ChEMBL




J Med Chem 60: 1262-1271 (2017)

More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 14


(Homo sapiens)
CHEMBL4101188
PNG
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.20E+3n/an/an/an/an/an/a



McDaniel College

Curated by ChEMBL




Bioorg Med Chem Lett 27: 2907-2911 (2017)


Article DOI: 10.1016/j.bmcl.2017.04.089
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 14


(Homo sapiens)
CHEMBL4101188
PNG
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.24E+3n/an/an/an/an/an/a



McDaniel College

Curated by ChEMBL




Bioorg Med Chem Lett 27: 2907-2911 (2017)


Article DOI: 10.1016/j.bmcl.2017.04.089
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 14


(Homo sapiens)
CHEMBL4084742
PNG
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.40E+3n/an/an/an/an/an/a



McDaniel College

Curated by ChEMBL




Bioorg Med Chem Lett 27: 2907-2911 (2017)


Article DOI: 10.1016/j.bmcl.2017.04.089
More data for this
Ligand-Target Pair
Human diphtheria toxin-like ADP-ribosyltransferase (ARTD8 or PARP14)


(Homo sapiens (Human))
BDBM50232346
PNG
(CHEMBL4101890)
Show SMILES C[C@H]1CN(C[C@@H](C)N1)c1cc(C)c(cn1)-c1ccc(cc1)-c1nc2n(C)ccc2c(=O)[nH]1 |r|
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 2.69E+3n/an/an/an/an/an/a



Health& Science University

Curated by ChEMBL




J Med Chem 60: 1262-1271 (2017)

More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 14


(Homo sapiens)
CHEMBL4059706
PNG
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.80E+3n/an/an/an/an/an/a



McDaniel College

Curated by ChEMBL




Bioorg Med Chem Lett 27: 2907-2911 (2017)


Article DOI: 10.1016/j.bmcl.2017.04.089
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 14


(Homo sapiens)
CHEMBL4059706
PNG
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.82E+3n/an/an/an/an/an/a



McDaniel College

Curated by ChEMBL




Bioorg Med Chem Lett 27: 2907-2911 (2017)


Article DOI: 10.1016/j.bmcl.2017.04.089
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 14


(Homo sapiens)
CHEMBL4081650
PNG
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.39E+3n/an/an/an/an/an/a



McDaniel College

Curated by ChEMBL




Bioorg Med Chem Lett 27: 2907-2911 (2017)


Article DOI: 10.1016/j.bmcl.2017.04.089
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 14


(Homo sapiens)
CHEMBL4081650
PNG
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.40E+3n/an/an/an/an/an/a



McDaniel College

Curated by ChEMBL




Bioorg Med Chem Lett 27: 2907-2911 (2017)


Article DOI: 10.1016/j.bmcl.2017.04.089
More data for this
Ligand-Target Pair
Human diphtheria toxin-like ADP-ribosyltransferase (ARTD8 or PARP14)


(Homo sapiens (Human))
BDBM50232346
PNG
(CHEMBL4101890)
Show SMILES C[C@H]1CN(C[C@@H](C)N1)c1cc(C)c(cn1)-c1ccc(cc1)-c1nc2n(C)ccc2c(=O)[nH]1 |r|
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 3.40E+3n/an/an/an/an/an/a



Health& Science University

Curated by ChEMBL




J Med Chem 60: 1262-1271 (2017)

More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 14


(Homo sapiens)
CHEMBL4093441
PNG
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.50E+3n/an/an/an/an/an/a



McDaniel College

Curated by ChEMBL




Bioorg Med Chem Lett 27: 2907-2911 (2017)


Article DOI: 10.1016/j.bmcl.2017.04.089
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 14


(Homo sapiens)
CHEMBL4093441
PNG
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.55E+3n/an/an/an/an/an/a



McDaniel College

Curated by ChEMBL


Assay Description
Inhibitory concentration against radioligand [3H]DTG binding to haloperidol-sensitive sigma binding site in whole guinea pig brain


Bioorg Med Chem Lett 27: 2907-2911 (2017)


Article DOI: 10.1016/j.bmcl.2017.04.089
More data for this
Ligand-Target Pair
Human diphtheria toxin-like ADP-ribosyltransferase (ARTD8 or PARP14)


(Homo sapiens (Human))
BDBM27497
PNG
(2-(dimethylamino)-N-(6-oxo-5,6-dihydrophenanthridi...)
Show SMILES CN(C)CC(=O)Nc1ccc2[nH]c(=O)c3ccccc3c2c1
Show InChI InChI=1S/C17H17N3O2/c1-20(2)10-16(21)18-11-7-8-15-14(9-11)12-5-3-4-6-13(12)17(22)19-15/h3-9H,10H2,1-2H3,(H,18,21)(H,19,22)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem

Patents

n/an/a 4.17E+3n/an/an/an/an/an/a



Health& Science University

Curated by ChEMBL




J Med Chem 60: 1262-1271 (2017)

More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 14


(Homo sapiens)
CHEMBL4097232
PNG
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.17E+3n/an/an/an/an/an/a



McDaniel College

Curated by ChEMBL




Bioorg Med Chem Lett 27: 2907-2911 (2017)


Article DOI: 10.1016/j.bmcl.2017.04.089
More data for this
Ligand-Target Pair
Poly [ADP-ribose] polymerase 14


(Homo sapiens)
CHEMBL4097232
PNG
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.20E+3n/an/an/an/an/an/a



McDaniel College

Curated by ChEMBL




Bioorg Med Chem Lett 27: 2907-2911 (2017)


Article DOI: 10.1016/j.bmcl.2017.04.089
More data for this
Ligand-Target Pair
Human diphtheria toxin-like ADP-ribosyltransferase (ARTD8 or PARP14)


(Homo sapiens (Human))
BDBM27497
PNG
(2-(dimethylamino)-N-(6-oxo-5,6-dihydrophenanthridi...)
Show SMILES CN(C)CC(=O)Nc1ccc2[nH]c(=O)c3ccccc3c2c1
Show InChI InChI=1S/C17H17N3O2/c1-20(2)10-16(21)18-11-7-8-15-14(9-11)12-5-3-4-6-13(12)17(22)19-15/h3-9H,10H2,1-2H3,(H,18,21)(H,19,22)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem

Patents

n/an/a 4.20E+3n/an/an/an/an/an/a



Health& Science University

Curated by ChEMBL




J Med Chem 60: 1262-1271 (2017)

More data for this
Ligand-Target Pair
Human diphtheria toxin-like ADP-ribosyltransferase (ARTD8 or PARP14)


(Homo sapiens (Human))
BDBM50238419
PNG
(CHEMBL4060134)
Show SMILES Cn1cnc(c1)C(=O)N1CCN(CC1)C(=O)c1ccc(Nc2nc3ccccc3n3nnnc23)cc1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a<5.01E+3n/an/an/an/an/an/a



Cellzome GmbH, A GlaxoSmithKline Company , Meyerhofstraße 1, 69117 Heidelberg, Germany.

Curated by ChEMBL




J Med Chem 60: 5455-5471 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00137
More data for this
Ligand-Target Pair
Human diphtheria toxin-like ADP-ribosyltransferase (ARTD8 or PARP14)


(Homo sapiens (Human))
BDBM50188594
PNG
(CHEBI:62878 | CHEMBL1086580)
Show SMILES Oc1nc(nc2CCSCc12)-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C14H11F3N2OS/c15-14(16,17)9-3-1-8(2-4-9)12-18-11-5-6-21-7-10(11)13(20)19-12/h1-4H,5-7H2,(H,18,19,20)
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n/an/a<5.01E+3n/an/an/an/an/an/a



Cellzome GmbH, A GlaxoSmithKline Company , Meyerhofstraße 1, 69117 Heidelberg, Germany.

Curated by ChEMBL




J Med Chem 60: 5455-5471 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00137
More data for this
Ligand-Target Pair
Human diphtheria toxin-like ADP-ribosyltransferase (ARTD8 or PARP14)


(Homo sapiens (Human))
BDBM50238428
PNG
(CHEMBL4087876)
Show SMILES O=C(N1CCOCC1)c1ccc(Nc2nc3ccccc3n3nnnc23)cc1
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n/an/a<5.01E+3n/an/an/an/an/an/a



Cellzome GmbH, A GlaxoSmithKline Company , Meyerhofstraße 1, 69117 Heidelberg, Germany.

Curated by ChEMBL




J Med Chem 60: 5455-5471 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00137
More data for this
Ligand-Target Pair
Human diphtheria toxin-like ADP-ribosyltransferase (ARTD8 or PARP14)


(Homo sapiens (Human))
BDBM50238416
PNG
(CHEMBL4087470)
Show SMILES O=C(N1CCN(CC1)c1ncccn1)c1ccc(Nc2nc3ccccc3n3nnnc23)cc1
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n/an/a<5.01E+3n/an/an/an/an/an/a



Cellzome GmbH, A GlaxoSmithKline Company , Meyerhofstraße 1, 69117 Heidelberg, Germany.

Curated by ChEMBL




J Med Chem 60: 5455-5471 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00137
More data for this
Ligand-Target Pair
Human diphtheria toxin-like ADP-ribosyltransferase (ARTD8 or PARP14)


(Homo sapiens (Human))
BDBM50238425
PNG
(CHEMBL4064332)
Show SMILES CC(C)c1ccc(Nc2nc3ccccc3n3nnnc23)cc1
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n/an/a<5.01E+3n/an/an/an/an/an/a



Cellzome GmbH, A GlaxoSmithKline Company , Meyerhofstraße 1, 69117 Heidelberg, Germany.

Curated by ChEMBL


Assay Description
Compound was evaluated for the inhibition of Leucine aminopeptidase and the inhibition constant was determined after preincubating the enzyme and inh...


J Med Chem 60: 5455-5471 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00137
More data for this
Ligand-Target Pair
Human diphtheria toxin-like ADP-ribosyltransferase (ARTD8 or PARP14)


(Homo sapiens (Human))
BDBM50232347
PNG
(CHEMBL4089840)
Show SMILES O=C(COc1cccc2c1cc[nH]c2=O)c1ccccc1
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n/an/a 5.70E+3n/an/an/an/an/an/a



Health& Science University

Curated by ChEMBL




J Med Chem 60: 1262-1271 (2017)

More data for this
Ligand-Target Pair
Human diphtheria toxin-like ADP-ribosyltransferase (ARTD8 or PARP14)


(Homo sapiens (Human))
BDBM50232347
PNG
(CHEMBL4089840)
Show SMILES O=C(COc1cccc2c1cc[nH]c2=O)c1ccccc1
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n/an/a 5.75E+3n/an/an/an/an/an/a



Health& Science University

Curated by ChEMBL




J Med Chem 60: 1262-1271 (2017)

More data for this
Ligand-Target Pair
Human diphtheria toxin-like ADP-ribosyltransferase (ARTD8 or PARP14)


(Homo sapiens (Human))
BDBM50188594
PNG
(CHEBI:62878 | CHEMBL1086580)
Show SMILES Oc1nc(nc2CCSCc12)-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C14H11F3N2OS/c15-14(16,17)9-3-1-8(2-4-9)12-18-11-5-6-21-7-10(11)13(20)19-12/h1-4H,5-7H2,(H,18,19,20)
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n/an/a 5.89E+3n/an/an/an/an/an/a



Health& Science University

Curated by ChEMBL




J Med Chem 60: 1262-1271 (2017)

More data for this
Ligand-Target Pair
Human diphtheria toxin-like ADP-ribosyltransferase (ARTD8 or PARP14)


(Homo sapiens (Human))
BDBM50188594
PNG
(CHEBI:62878 | CHEMBL1086580)
Show SMILES Oc1nc(nc2CCSCc12)-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C14H11F3N2OS/c15-14(16,17)9-3-1-8(2-4-9)12-18-11-5-6-21-7-10(11)13(20)19-12/h1-4H,5-7H2,(H,18,19,20)
PDB

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n/an/a 5.90E+3n/an/an/an/an/an/a



Health& Science University

Curated by ChEMBL




J Med Chem 60: 1262-1271 (2017)

More data for this
Ligand-Target Pair
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