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Compile Data Set for Download or QSAR

Found 1275 hits Enz. Inhib. hit(s) with Target = 'Prostanoid EP2 receptor'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM263346
PNG
(US9546162, 4)
Show SMILES OC(=O)c1ccc(CCc2cccc3CCN(Cc4cc(cc(c4)C(F)(F)F)C(F)(F)F)c23)cc1
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0.300n/an/an/a 11n/an/a7.4n/a



ALLERGAN, INC.

US Patent




US Patent US9546162 (2017)


BindingDB Entry DOI: 10.7270/Q2P55QHV
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM179992
PNG
(US9676720, Example 2)
Show SMILES C\C=C\c1cccc(c1)-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2ccccn2)cc1
Show InChI InChI=1S/C29H28N4O4S/c1-2-7-22-8-5-9-25(18-22)24-15-13-23(14-16-24)20-33(38(36,37)28-12-3-4-17-30-28)21-26-10-6-11-27(32-26)31-19-29(34)35/h2-18H,19-21H2,1H3,(H,31,32)(H,34,35)/b7-2+
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0.530n/an/an/an/an/an/a6.0n/a



UBE INDUSTRIES, LTD.

US Patent


Assay Description
Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...


US Patent US9676720 (2017)


BindingDB Entry DOI: 10.7270/Q2057D39
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM179995
PNG
(US9676720, Example 7)
Show SMILES CCOc1cccc(c1)-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2ccccn2)cc1
Show InChI InChI=1S/C28H28N4O5S/c1-2-37-25-9-5-7-23(17-25)22-14-12-21(13-15-22)19-32(38(35,36)27-11-3-4-16-29-27)20-24-8-6-10-26(31-24)30-18-28(33)34/h3-17H,2,18-20H2,1H3,(H,30,31)(H,33,34)
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0.610n/an/an/an/an/an/a6.0n/a



UBE INDUSTRIES, LTD.

US Patent


Assay Description
Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...


US Patent US9676720 (2017)


BindingDB Entry DOI: 10.7270/Q2057D39
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM50101830
PNG
((Z)-7-{(1R,2R,3R,5R)-5-Chloro-2-[(E)-(S)-4-(1-ethy...)
Show SMILES CCC1(CCC1)[C@@H](O)C\C=C\[C@H]1[C@H](O)C[C@@H](Cl)[C@@H]1C\C=C/CCCC(O)=O
Show InChI InChI=1S/C22H35ClO4/c1-2-22(13-8-14-22)20(25)11-7-10-17-16(18(23)15-19(17)24)9-5-3-4-6-12-21(26)27/h3,5,7,10,16-20,24-25H,2,4,6,8-9,11-15H2,1H3,(H,26,27)/b5-3-,10-7+/t16-,17-,18-,19-,20+/m1/s1
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0.740n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Compound was evaluated for its competitive binding affinity towards human Prostanoid EP2 receptor in CHO cells expressing prostanoid receptor


Bioorg Med Chem Lett 11: 2025-8 (2001)


BindingDB Entry DOI: 10.7270/Q2CV4H1T
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM179994
PNG
(US9676720, Example 6)
Show SMILES CC#Cc1cccc(c1)-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2cccnc2)cc1
Show InChI InChI=1S/C29H26N4O4S/c1-2-6-22-7-3-8-25(17-22)24-14-12-23(13-15-24)20-33(38(36,37)27-10-5-16-30-18-27)21-26-9-4-11-28(32-26)31-19-29(34)35/h3-5,7-18H,19-21H2,1H3,(H,31,32)(H,34,35)
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0.75n/an/an/an/an/an/a6.0n/a



UBE INDUSTRIES, LTD.

US Patent


Assay Description
Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...


US Patent US9676720 (2017)


BindingDB Entry DOI: 10.7270/Q2057D39
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM180045
PNG
(US9676720, Comparative example 16)
Show SMILES CC#Cc1ccccc1-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2ccccn2)cc1
Show InChI InChI=1S/C29H26N4O4S/c1-2-8-23-9-3-4-11-26(23)24-16-14-22(15-17-24)20-33(38(36,37)28-13-5-6-18-30-28)21-25-10-7-12-27(32-25)31-19-29(34)35/h3-7,9-18H,19-21H2,1H3,(H,31,32)(H,34,35)
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0.75n/an/an/an/an/an/a6.0n/a



UBE INDUSTRIES, LTD.

US Patent


Assay Description
Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...


US Patent US9676720 (2017)


BindingDB Entry DOI: 10.7270/Q2057D39
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM179998
PNG
(US9676720, Example 11)
Show SMILES CCOc1cccc(c1)-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2cccs2)cc1
Show InChI InChI=1S/C27H27N3O5S2/c1-2-35-24-8-3-6-22(16-24)21-13-11-20(12-14-21)18-30(37(33,34)27-10-5-15-36-27)19-23-7-4-9-25(29-23)28-17-26(31)32/h3-16H,2,17-19H2,1H3,(H,28,29)(H,31,32)
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0.790n/an/an/an/an/an/a6.0n/a



UBE INDUSTRIES, LTD.

US Patent


Assay Description
Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...


US Patent US9676720 (2017)


BindingDB Entry DOI: 10.7270/Q2057D39
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM179993
PNG
(US9676720, Example 4)
Show SMILES CC#Cc1cccc(c1)-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2ccccn2)cc1
Show InChI InChI=1S/C29H26N4O4S/c1-2-7-22-8-5-9-25(18-22)24-15-13-23(14-16-24)20-33(38(36,37)28-12-3-4-17-30-28)21-26-10-6-11-27(32-26)31-19-29(34)35/h3-6,8-18H,19-21H2,1H3,(H,31,32)(H,34,35)
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0.800n/an/an/an/an/an/a6.0n/a



UBE INDUSTRIES, LTD.

US Patent


Assay Description
Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...


US Patent US9676720 (2017)


BindingDB Entry DOI: 10.7270/Q2057D39
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM179996
PNG
(US9676720, Example 9)
Show SMILES CCOc1cccc(c1)-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2cccnc2)cc1
Show InChI InChI=1S/C28H28N4O5S/c1-2-37-25-8-3-6-23(16-25)22-13-11-21(12-14-22)19-32(38(35,36)26-9-5-15-29-17-26)20-24-7-4-10-27(31-24)30-18-28(33)34/h3-17H,2,18-20H2,1H3,(H,30,31)(H,33,34)
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0.800n/an/an/an/an/an/a6.0n/a



UBE INDUSTRIES, LTD.

US Patent


Assay Description
Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...


US Patent US9676720 (2017)


BindingDB Entry DOI: 10.7270/Q2057D39
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM180000
PNG
(US9676720, Example 14)
Show SMILES CC#Cc1cccc(c1)-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2cccs2)cc1
Show InChI InChI=1S/C28H25N3O4S2/c1-2-6-21-7-3-8-24(17-21)23-14-12-22(13-15-23)19-31(37(34,35)28-11-5-16-36-28)20-25-9-4-10-26(30-25)29-18-27(32)33/h3-5,7-17H,18-20H2,1H3,(H,29,30)(H,32,33)
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0.900n/an/an/an/an/an/a6.0n/a



UBE INDUSTRIES, LTD.

US Patent


Assay Description
Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...


US Patent US9676720 (2017)


BindingDB Entry DOI: 10.7270/Q2057D39
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM179999
PNG
(US9676720, Example 12)
Show SMILES CCOc1cccc(n1)-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2ccccn2)cc1
Show InChI InChI=1S/C27H27N5O5S/c1-2-37-25-10-6-8-23(31-25)21-14-12-20(13-15-21)18-32(38(35,36)26-11-3-4-16-28-26)19-22-7-5-9-24(30-22)29-17-27(33)34/h3-16H,2,17-19H2,1H3,(H,29,30)(H,33,34)
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0.940n/an/an/an/an/an/a6.0n/a



UBE INDUSTRIES, LTD.

US Patent


Assay Description
Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...


US Patent US9676720 (2017)


BindingDB Entry DOI: 10.7270/Q2057D39
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM180002
PNG
(US9676720, Example 16)
Show SMILES CC#Cc1cccc(c1)-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2ccccc2)cc1
Show InChI InChI=1S/C30H27N3O4S/c1-2-8-23-9-6-10-26(19-23)25-17-15-24(16-18-25)21-33(38(36,37)28-12-4-3-5-13-28)22-27-11-7-14-29(32-27)31-20-30(34)35/h3-7,9-19H,20-22H2,1H3,(H,31,32)(H,34,35)
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0.950n/an/an/an/an/an/a6.0n/a



UBE INDUSTRIES, LTD.

US Patent


Assay Description
Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...


US Patent US9676720 (2017)


BindingDB Entry DOI: 10.7270/Q2057D39
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM179997
PNG
(US9676720, Example 10)
Show SMILES CCOc1cccc(c1)-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2ccccc2)cc1
Show InChI InChI=1S/C29H29N3O5S/c1-2-37-26-10-6-8-24(18-26)23-16-14-22(15-17-23)20-32(38(35,36)27-11-4-3-5-12-27)21-25-9-7-13-28(31-25)30-19-29(33)34/h3-18H,2,19-21H2,1H3,(H,30,31)(H,33,34)
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0.970n/an/an/an/an/an/a6.0n/a



UBE INDUSTRIES, LTD.

US Patent


Assay Description
Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...


US Patent US9676720 (2017)


BindingDB Entry DOI: 10.7270/Q2057D39
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM180003
PNG
(US9676720, Example 18)
Show SMILES CC#Cc1cccc(c1)-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2ccsc2)cc1
Show InChI InChI=1S/C28H25N3O4S2/c1-2-5-21-6-3-7-24(16-21)23-12-10-22(11-13-23)18-31(37(34,35)26-14-15-36-20-26)19-25-8-4-9-27(30-25)29-17-28(32)33/h3-4,6-16,20H,17-19H2,1H3,(H,29,30)(H,32,33)
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0.990n/an/an/an/an/an/a6.0n/a



UBE INDUSTRIES, LTD.

US Patent


Assay Description
Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...


US Patent US9676720 (2017)


BindingDB Entry DOI: 10.7270/Q2057D39
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM180020
PNG
(US9676720, Comparative example 8)
Show SMILES CCCc1cccc(c1)-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2ccccn2)cc1
Show InChI InChI=1S/C29H30N4O4S/c1-2-7-22-8-5-9-25(18-22)24-15-13-23(14-16-24)20-33(38(36,37)28-12-3-4-17-30-28)21-26-10-6-11-27(32-26)31-19-29(34)35/h3-6,8-18H,2,7,19-21H2,1H3,(H,31,32)(H,34,35)
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1.10n/an/an/an/an/an/a6.0n/a



UBE INDUSTRIES, LTD.

US Patent


Assay Description
Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...


US Patent US9676720 (2017)


BindingDB Entry DOI: 10.7270/Q2057D39
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM119438
PNG
(BDBM119693 | US8685986, 12)
Show SMILES ONC(=O)c1ccc(CNC(=O)c2[nH]c(cc2-c2ccc(F)cc2)-c2ccoc2)cc1
Show InChI InChI=1S/C23H18FN3O4/c24-18-7-5-15(6-8-18)19-11-20(17-9-10-31-13-17)26-21(19)23(29)25-12-14-1-3-16(4-2-14)22(28)27-30/h1-11,13,26,30H,12H2,(H,25,29)(H,27,28)
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1.10 -52.0n/an/an/an/an/a6.030



Ube Industries, Ltd.

US Patent


Assay Description
Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...


US Patent US8685986 (2014)


BindingDB Entry DOI: 10.7270/Q28S4NK1
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM180024
PNG
(US9676720, Comparative example 11)
Show SMILES COc1cccc(c1)-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2ccccn2)cc1
Show InChI InChI=1S/C27H26N4O5S/c1-36-24-8-4-6-22(16-24)21-13-11-20(12-14-21)18-31(37(34,35)26-10-2-3-15-28-26)19-23-7-5-9-25(30-23)29-17-27(32)33/h2-16H,17-19H2,1H3,(H,29,30)(H,32,33)
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1.20n/an/an/an/an/an/a6.0n/a



UBE INDUSTRIES, LTD.

US Patent


Assay Description
Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...


US Patent US9676720 (2017)


BindingDB Entry DOI: 10.7270/Q2057D39
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM180019
PNG
(US9676720, Comparative example 7)
Show SMILES CCc1cccc(c1)-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2ccccn2)cc1
Show InChI InChI=1S/C28H28N4O4S/c1-2-21-7-5-8-24(17-21)23-14-12-22(13-15-23)19-32(37(35,36)27-11-3-4-16-29-27)20-25-9-6-10-26(31-25)30-18-28(33)34/h3-17H,2,18-20H2,1H3,(H,30,31)(H,33,34)
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1.40n/an/an/an/an/an/a6.0n/a



UBE INDUSTRIES, LTD.

US Patent


Assay Description
Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...


US Patent US9676720 (2017)


BindingDB Entry DOI: 10.7270/Q2057D39
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM180004
PNG
(US9676720, Example 19)
Show SMILES CC#Cc1cccc(c1)-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2cccc(F)c2)cc1
Show InChI InChI=1S/C30H26FN3O4S/c1-2-6-22-7-3-8-25(17-22)24-15-13-23(14-16-24)20-34(39(37,38)28-11-4-9-26(31)18-28)21-27-10-5-12-29(33-27)32-19-30(35)36/h3-5,7-18H,19-21H2,1H3,(H,32,33)(H,35,36)
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UBE INDUSTRIES, LTD.

US Patent


Assay Description
Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...


US Patent US9676720 (2017)


BindingDB Entry DOI: 10.7270/Q2057D39
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM180021
PNG
(US9676720, Comparative example 9)
Show SMILES CC\C=C\c1cccc(c1)-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2ccccn2)cc1
Show InChI InChI=1S/C30H30N4O4S/c1-2-3-8-23-9-6-10-26(19-23)25-16-14-24(15-17-25)21-34(39(37,38)29-13-4-5-18-31-29)22-27-11-7-12-28(33-27)32-20-30(35)36/h3-19H,2,20-22H2,1H3,(H,32,33)(H,35,36)/b8-3+
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1.5n/an/an/an/an/an/a6.0n/a



UBE INDUSTRIES, LTD.

US Patent


Assay Description
Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...


US Patent US9676720 (2017)


BindingDB Entry DOI: 10.7270/Q2057D39
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM119442
PNG
(US8685986, 17)
Show SMILES ONC(=O)c1ccc(CNC(=O)c2[nH]c(cc2-c2ccc(F)cc2)-c2ccccc2)o1
Show InChI InChI=1S/C23H18FN3O4/c24-16-8-6-14(7-9-16)18-12-19(15-4-2-1-3-5-15)26-21(18)23(29)25-13-17-10-11-20(31-17)22(28)27-30/h1-12,26,30H,13H2,(H,25,29)(H,27,28)
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1.5 -51.2n/an/an/an/an/a6.030



Ube Industries, Ltd.

US Patent


Assay Description
Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...


US Patent US8685986 (2014)


BindingDB Entry DOI: 10.7270/Q28S4NK1
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM180005
PNG
(US9676720, Comparative example 1)
Show SMILES OC(=O)CNc1cccc(CN(Cc2ccc(cc2)-c2ccccc2)S(=O)(=O)c2ccccn2)n1
Show InChI InChI=1S/C26H24N4O4S/c31-26(32)17-28-24-10-6-9-23(29-24)19-30(35(33,34)25-11-4-5-16-27-25)18-20-12-14-22(15-13-20)21-7-2-1-3-8-21/h1-16H,17-19H2,(H,28,29)(H,31,32)
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1.5n/an/an/an/an/an/a6.0n/a



UBE INDUSTRIES, LTD.

US Patent


Assay Description
Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...


US Patent US9676720 (2017)


BindingDB Entry DOI: 10.7270/Q2057D39
More data for this
Ligand-Target Pair
Prostanoid EP2 Receptor


(Mus musculus (Mouse))
BDBM50385141
PNG
(CHEMBL2036321)
Show SMILES Cc1ccc(cc1C)-c1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)N2CCSc2nc(cs2)C(O)=O)c1 |r|
Show InChI InChI=1S/C28H30N2O4S2/c1-18-6-7-22(14-19(18)2)21-5-3-4-20(15-21)16-24(31)10-8-23-9-11-26(32)30(23)12-13-35-28-29-25(17-36-28)27(33)34/h3-8,10,14-15,17,23-24,31H,9,11-13,16H2,1-2H3,(H,33,34)/b10-8+/t23-,24+/m0/s1
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1.5n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counting


Bioorg Med Chem 20: 3502-22 (2012)


Article DOI: 10.1016/j.bmc.2012.04.008
BindingDB Entry DOI: 10.7270/Q2D50P0B
More data for this
Ligand-Target Pair
Prostanoid EP2 Receptor


(Mus musculus (Mouse))
BDBM50366137
PNG
(CHEMBL1957436)
Show SMILES O[C@@H](Cc1cccc(c1)-c1ccc(Cl)cc1)\C=C\[C@H]1CCC(=O)N1CCSc1nc(cs1)C(O)=O |r|
Show InChI InChI=1S/C26H25ClN2O4S2/c27-20-6-4-18(5-7-20)19-3-1-2-17(14-19)15-22(30)10-8-21-9-11-24(31)29(21)12-13-34-26-28-23(16-35-26)25(32)33/h1-8,10,14,16,21-22,30H,9,11-13,15H2,(H,32,33)/b10-8+/t21-,22+/m0/s1
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1.70n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counting


Bioorg Med Chem 20: 2235-51 (2012)


Article DOI: 10.1016/j.bmc.2012.02.018
BindingDB Entry DOI: 10.7270/Q2542P2G
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM50016952
PNG
(CHEMBL3286796)
Show SMILES O[C@@H](C\C=C\[C@H]1[C@H](O)C[C@@H](Cl)[C@@H]1C\C=C/CCCC(O)=O)C1(CC=C)CCC1 |r|
Show InChI InChI=1S/C23H35ClO4/c1-2-13-23(14-8-15-23)21(26)11-7-10-18-17(19(24)16-20(18)25)9-5-3-4-6-12-22(27)28/h2-3,5,7,10,17-21,25-26H,1,4,6,8-9,11-16H2,(H,27,28)/b5-3-,10-7+/t17-,18-,19-,20-,21+/m1/s1
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1.70n/an/an/an/an/an/an/an/a



Emory University School of Medicine

Curated by ChEMBL


Assay Description
Binding affinity to EP2 receptor (unknown origin) by competitive binding assay


J Med Chem 57: 4454-65 (2014)


Article DOI: 10.1021/jm401431x
BindingDB Entry DOI: 10.7270/Q2CR5VXZ
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM180022
PNG
(US9676720, Comparative example 10)
Show SMILES OC(=O)CNc1cccc(CN(Cc2ccc(cc2)-c2cccc(CC=C)c2)S(=O)(=O)c2ccccn2)n1
Show InChI InChI=1S/C29H28N4O4S/c1-2-7-22-8-5-9-25(18-22)24-15-13-23(14-16-24)20-33(38(36,37)28-12-3-4-17-30-28)21-26-10-6-11-27(32-26)31-19-29(34)35/h2-6,8-18H,1,7,19-21H2,(H,31,32)(H,34,35)
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1.70n/an/an/an/an/an/a6.0n/a



UBE INDUSTRIES, LTD.

US Patent


Assay Description
Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...


US Patent US9676720 (2017)


BindingDB Entry DOI: 10.7270/Q2057D39
More data for this
Ligand-Target Pair
Prostanoid EP2 Receptor


(Mus musculus (Mouse))
BDBM50366137
PNG
(CHEMBL1957436)
Show SMILES O[C@@H](Cc1cccc(c1)-c1ccc(Cl)cc1)\C=C\[C@H]1CCC(=O)N1CCSc1nc(cs1)C(O)=O |r|
Show InChI InChI=1S/C26H25ClN2O4S2/c27-20-6-4-18(5-7-20)19-3-1-2-17(14-19)15-22(30)10-8-21-9-11-24(31)29(21)12-13-34-26-28-23(16-35-26)25(32)33/h1-8,10,14,16,21-22,30H,9,11-13,15H2,(H,32,33)/b10-8+/t21-,22+/m0/s1
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1.70n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counting


Bioorg Med Chem 20: 3502-22 (2012)


Article DOI: 10.1016/j.bmc.2012.04.008
BindingDB Entry DOI: 10.7270/Q2D50P0B
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM119432
PNG
(US8685986, 3)
Show SMILES OC(=O)c1[nH]c(cc1-c1ccc(F)cc1)-c1cccs1
Show InChI InChI=1S/C15H10FNO2S/c16-10-5-3-9(4-6-10)11-8-12(13-2-1-7-20-13)17-14(11)15(18)19/h1-8,17H,(H,18,19)
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1.90 -50.6n/an/an/an/an/a6.030



Ube Industries, Ltd.

US Patent


Assay Description
Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...


US Patent US8685986 (2014)


BindingDB Entry DOI: 10.7270/Q28S4NK1
More data for this
Ligand-Target Pair
Prostanoid EP2 Receptor


(Mus musculus (Mouse))
BDBM50385128
PNG
(CHEMBL2036318)
Show SMILES Cc1ccc(cc1)-c1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)N2CCSc2nc(cs2)C(O)=O)c1 |r|
Show InChI InChI=1S/C27H28N2O4S2/c1-18-5-7-20(8-6-18)21-4-2-3-19(15-21)16-23(30)11-9-22-10-12-25(31)29(22)13-14-34-27-28-24(17-35-27)26(32)33/h2-9,11,15,17,22-23,30H,10,12-14,16H2,1H3,(H,32,33)/b11-9+/t22-,23+/m0/s1
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2n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counting


Bioorg Med Chem 20: 3502-22 (2012)


Article DOI: 10.1016/j.bmc.2012.04.008
BindingDB Entry DOI: 10.7270/Q2D50P0B
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM263343
PNG
(US9546162, 1)
Show SMILES OC(=O)c1ccc(CCc2cccc3CCN(Cc4cccc(F)c4)c23)cc1
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2n/an/an/an/an/an/a7.4n/a



ALLERGAN, INC.

US Patent




US Patent US9546162 (2017)


BindingDB Entry DOI: 10.7270/Q2P55QHV
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM180025
PNG
(US9676720, Comparative example 12)
Show SMILES CCCOc1cccc(n1)-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2ccccn2)cc1
Show InChI InChI=1S/C28H29N5O5S/c1-2-17-38-26-10-6-8-24(32-26)22-14-12-21(13-15-22)19-33(39(36,37)27-11-3-4-16-29-27)20-23-7-5-9-25(31-23)30-18-28(34)35/h3-16H,2,17-20H2,1H3,(H,30,31)(H,34,35)
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2n/an/an/an/an/an/a6.0n/a



UBE INDUSTRIES, LTD.

US Patent


Assay Description
Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...


US Patent US9676720 (2017)


BindingDB Entry DOI: 10.7270/Q2057D39
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM263347
PNG
(US9546162, 5)
Show SMILES COc1cc(CO)cc(CN2CCc3cccc(CCc4ccc(cc4)C(O)=O)c23)c1
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2n/an/an/a 11n/an/a7.4n/a



ALLERGAN, INC.

US Patent




US Patent US9546162 (2017)


BindingDB Entry DOI: 10.7270/Q2P55QHV
More data for this
Ligand-Target Pair
Prostanoid EP2 Receptor


(Mus musculus (Mouse))
BDBM50385131
PNG
(CHEMBL2036322)
Show SMILES O[C@@H](Cc1cccc(c1)-c1cc2ccccc2o1)\C=C\[C@H]1CCC(=O)N1CCSc1nc(cs1)C(O)=O |r|
Show InChI InChI=1S/C28H26N2O5S2/c31-22(15-18-4-3-6-19(14-18)25-16-20-5-1-2-7-24(20)35-25)10-8-21-9-11-26(32)30(21)12-13-36-28-29-23(17-37-28)27(33)34/h1-8,10,14,16-17,21-22,31H,9,11-13,15H2,(H,33,34)/b10-8+/t21-,22+/m0/s1
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2.10n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counting


Bioorg Med Chem 20: 3502-22 (2012)


Article DOI: 10.1016/j.bmc.2012.04.008
BindingDB Entry DOI: 10.7270/Q2D50P0B
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM180018
PNG
(US9676720, Comparative example 6)
Show SMILES Cc1cccc(c1)-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2ccccn2)cc1
Show InChI InChI=1S/C27H26N4O4S/c1-20-6-4-7-23(16-20)22-13-11-21(12-14-22)18-31(36(34,35)26-10-2-3-15-28-26)19-24-8-5-9-25(30-24)29-17-27(32)33/h2-16H,17-19H2,1H3,(H,29,30)(H,32,33)
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2.20n/an/an/an/an/an/a6.0n/a



UBE INDUSTRIES, LTD.

US Patent


Assay Description
Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...


US Patent US9676720 (2017)


BindingDB Entry DOI: 10.7270/Q2057D39
More data for this
Ligand-Target Pair
Prostanoid EP2 Receptor


(Mus musculus (Mouse))
BDBM50101830
PNG
((Z)-7-{(1R,2R,3R,5R)-5-Chloro-2-[(E)-(S)-4-(1-ethy...)
Show SMILES CCC1(CCC1)[C@@H](O)C\C=C\[C@H]1[C@H](O)C[C@@H](Cl)[C@@H]1C\C=C/CCCC(O)=O
Show InChI InChI=1S/C22H35ClO4/c1-2-22(13-8-14-22)20(25)11-7-10-17-16(18(23)15-19(17)24)9-5-3-4-6-12-21(26)27/h3,5,7,10,16-20,24-25H,2,4,6,8-9,11-15H2,1H3,(H,26,27)/b5-3-,10-7+/t16-,17-,18-,19-,20+/m1/s1
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2.20n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Binding affinity towards mouse Prostanoid EP2 receptor expressed in CHO cells.


Bioorg Med Chem Lett 11: 2025-8 (2001)


BindingDB Entry DOI: 10.7270/Q2CV4H1T
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM180026
PNG
(US9676720, Comparative example 13)
Show SMILES CCOc1ccccc1-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2ccccn2)cc1
Show InChI InChI=1S/C28H28N4O5S/c1-2-37-25-10-4-3-9-24(25)22-15-13-21(14-16-22)19-32(38(35,36)27-12-5-6-17-29-27)20-23-8-7-11-26(31-23)30-18-28(33)34/h3-17H,2,18-20H2,1H3,(H,30,31)(H,33,34)
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2.60n/an/an/an/an/an/a6.0n/a



UBE INDUSTRIES, LTD.

US Patent


Assay Description
Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...


US Patent US9676720 (2017)


BindingDB Entry DOI: 10.7270/Q2057D39
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM119433
PNG
(US8685986, 4)
Show SMILES OC(=O)c1[nH]c(cc1-c1ccc(O)cc1)-c1ccoc1
Show InChI InChI=1S/C15H11NO4/c17-11-3-1-9(2-4-11)12-7-13(10-5-6-20-8-10)16-14(12)15(18)19/h1-8,16-17H,(H,18,19)
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2.80 -49.6n/an/an/an/an/a6.030



Ube Industries, Ltd.

US Patent


Assay Description
Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...


US Patent US8685986 (2014)


BindingDB Entry DOI: 10.7270/Q28S4NK1
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM263363
PNG
(US9546162, 21)
Show SMILES COc1cccc(CN2CCc3cccc(CCc4ccc(cc4)C(O)=O)c23)c1
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23n/an/an/an/an/an/a7.4n/a



ALLERGAN, INC.

US Patent




US Patent US9546162 (2017)


BindingDB Entry DOI: 10.7270/Q2P55QHV
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM263357
PNG
(US9546162, 15)
Show SMILES COc1cccc(Cn2ccc3cccc(CCc4ccc(cc4)C(O)=O)c23)c1
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3n/an/an/a 11n/an/a7.4n/a



ALLERGAN, INC.

US Patent




US Patent US9546162 (2017)


BindingDB Entry DOI: 10.7270/Q2P55QHV
More data for this
Ligand-Target Pair
Prostanoid EP2 Receptor


(Mus musculus (Mouse))
BDBM50360628
PNG
(CHEMBL1933724)
Show SMILES CCCCC[C@H](O)\C=C\[C@H]1CCC(=O)N1CCSc1nc(cs1)C(O)=O |r|
Show InChI InChI=1S/C18H26N2O4S2/c1-2-3-4-5-14(21)8-6-13-7-9-16(22)20(13)10-11-25-18-19-15(12-26-18)17(23)24/h6,8,12-14,21H,2-5,7,9-11H2,1H3,(H,23,24)/b8-6+/t13-,14-/m0/s1
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3n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by liquid scintillation counting


Bioorg Med Chem Lett 22: 396-401 (2011)


Article DOI: 10.1016/j.bmcl.2011.10.109
BindingDB Entry DOI: 10.7270/Q27P8ZT2
More data for this
Ligand-Target Pair
Prostanoid EP2 Receptor


(Mus musculus (Mouse))
BDBM50360628
PNG
(CHEMBL1933724)
Show SMILES CCCCC[C@H](O)\C=C\[C@H]1CCC(=O)N1CCSc1nc(cs1)C(O)=O |r|
Show InChI InChI=1S/C18H26N2O4S2/c1-2-3-4-5-14(21)8-6-13-7-9-16(22)20(13)10-11-25-18-19-15(12-26-18)17(23)24/h6,8,12-14,21H,2-5,7,9-11H2,1H3,(H,23,24)/b8-6+/t13-,14-/m0/s1
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3n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counting


Bioorg Med Chem 20: 2235-51 (2012)


Article DOI: 10.1016/j.bmc.2012.02.018
BindingDB Entry DOI: 10.7270/Q2542P2G
More data for this
Ligand-Target Pair
Prostanoid EP2 Receptor


(Mus musculus (Mouse))
BDBM50366136
PNG
(CHEMBL1957435)
Show SMILES O[C@@H](Cc1cccc(c1)-c1ccccc1)\C=C\[C@H]1CCC(=O)N1CCSc1nc(cs1)C(O)=O |r|
Show InChI InChI=1S/C26H26N2O4S2/c29-22(16-18-5-4-8-20(15-18)19-6-2-1-3-7-19)11-9-21-10-12-24(30)28(21)13-14-33-26-27-23(17-34-26)25(31)32/h1-9,11,15,17,21-22,29H,10,12-14,16H2,(H,31,32)/b11-9+/t21-,22+/m0/s1
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3n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counting


Bioorg Med Chem 20: 3502-22 (2012)


Article DOI: 10.1016/j.bmc.2012.04.008
BindingDB Entry DOI: 10.7270/Q2D50P0B
More data for this
Ligand-Target Pair
Prostanoid EP2 Receptor


(Mus musculus (Mouse))
BDBM50366136
PNG
(CHEMBL1957435)
Show SMILES O[C@@H](Cc1cccc(c1)-c1ccccc1)\C=C\[C@H]1CCC(=O)N1CCSc1nc(cs1)C(O)=O |r|
Show InChI InChI=1S/C26H26N2O4S2/c29-22(16-18-5-4-8-20(15-18)19-6-2-1-3-7-19)11-9-21-10-12-24(30)28(21)13-14-33-26-27-23(17-34-26)25(31)32/h1-9,11,15,17,21-22,29H,10,12-14,16H2,(H,31,32)/b11-9+/t21-,22+/m0/s1
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3n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counting


Bioorg Med Chem 20: 2235-51 (2012)


Article DOI: 10.1016/j.bmc.2012.02.018
BindingDB Entry DOI: 10.7270/Q2542P2G
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM119441
PNG
(US8685986, 16)
Show SMILES COc1ccc(cc1)-c1cc([nH]c1C(=O)Nc1ccc(o1)C(=O)NO)-c1ccccc1
Show InChI InChI=1S/C23H19N3O5/c1-30-16-9-7-14(8-10-16)17-13-18(15-5-3-2-4-6-15)24-21(17)23(28)25-20-12-11-19(31-20)22(27)26-29/h2-13,24,29H,1H3,(H,25,28)(H,26,27)
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3.10 -49.4n/an/an/an/an/a6.030



Ube Industries, Ltd.

US Patent


Assay Description
Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...


US Patent US8685986 (2014)


BindingDB Entry DOI: 10.7270/Q28S4NK1
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM180038
PNG
(US9676720, Comparative example 15)
Show SMILES CCOc1cc(ccn1)-c1ccc(CN(Cc2cccc(NCC(O)=O)n2)S(=O)(=O)c2ccccc2)cc1
Show InChI InChI=1S/C28H28N4O5S/c1-2-37-27-17-23(15-16-29-27)22-13-11-21(12-14-22)19-32(38(35,36)25-8-4-3-5-9-25)20-24-7-6-10-26(31-24)30-18-28(33)34/h3-17H,2,18-20H2,1H3,(H,30,31)(H,33,34)
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3.20n/an/an/an/an/an/a6.0n/a



UBE INDUSTRIES, LTD.

US Patent


Assay Description
Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...


US Patent US9676720 (2017)


BindingDB Entry DOI: 10.7270/Q2057D39
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM50101830
PNG
((Z)-7-{(1R,2R,3R,5R)-5-Chloro-2-[(E)-(S)-4-(1-ethy...)
Show SMILES CCC1(CCC1)[C@@H](O)C\C=C\[C@H]1[C@H](O)C[C@@H](Cl)[C@@H]1C\C=C/CCCC(O)=O
Show InChI InChI=1S/C22H35ClO4/c1-2-22(13-8-14-22)20(25)11-7-10-17-16(18(23)15-19(17)24)9-5-3-4-6-12-21(26)27/h3,5,7,10,16-20,24-25H,2,4,6,8-9,11-15H2,1H3,(H,26,27)/b5-3-,10-7+/t16-,17-,18-,19-,20+/m1/s1
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3.30n/an/an/an/an/an/an/an/a



Emory University School of Medicine

Curated by ChEMBL


Assay Description
Binding affinity to EP2 receptor (unknown origin) by competitive binding assay


J Med Chem 57: 4454-65 (2014)


Article DOI: 10.1021/jm401431x
BindingDB Entry DOI: 10.7270/Q2CR5VXZ
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM180006
PNG
(US9676720, Comparative example 2)
Show SMILES OC(=O)CNc1cccc(CN(Cc2ccc(cc2)-c2ccccc2)S(=O)(=O)c2cccnc2)n1
Show InChI InChI=1S/C26H24N4O4S/c31-26(32)17-28-25-10-4-8-23(29-25)19-30(35(33,34)24-9-5-15-27-16-24)18-20-11-13-22(14-12-20)21-6-2-1-3-7-21/h1-16H,17-19H2,(H,28,29)(H,31,32)
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3.80n/an/an/an/an/an/a6.0n/a



UBE INDUSTRIES, LTD.

US Patent


Assay Description
Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285...


US Patent US9676720 (2017)


BindingDB Entry DOI: 10.7270/Q2057D39
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM119435
PNG
(US8685986, 6)
Show SMILES COC(=O)c1ccc(CNC(=O)c2[nH]c(cc2-c2ccc(F)cc2)-c2cccs2)nc1
Show InChI InChI=1S/C23H18FN3O3S/c1-30-23(29)15-6-9-17(25-12-15)13-26-22(28)21-18(14-4-7-16(24)8-5-14)11-19(27-21)20-3-2-10-31-20/h2-12,27H,13H2,1H3,(H,26,28)
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3.80 -48.9n/an/an/an/an/a6.030



Ube Industries, Ltd.

US Patent


Assay Description
Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...


US Patent US8685986 (2014)


BindingDB Entry DOI: 10.7270/Q28S4NK1
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM119437
PNG
(US8685986, 11)
Show SMILES ONC(=O)c1ccc(CNC(=O)c2[nH]c(cc2-c2ccc(F)cc2)-c2cccs2)nc1
Show InChI InChI=1S/C22H17FN4O3S/c23-15-6-3-13(4-7-15)17-10-18(19-2-1-9-31-19)26-20(17)22(29)25-12-16-8-5-14(11-24-16)21(28)27-30/h1-11,26,30H,12H2,(H,25,29)(H,27,28)
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3.80 -48.9n/an/an/an/an/a6.030



Ube Industries, Ltd.

US Patent


Assay Description
Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...


US Patent US8685986 (2014)


BindingDB Entry DOI: 10.7270/Q28S4NK1
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM119436
PNG
(US8685986, 9)
Show SMILES ONC(=O)c1ccc(CNC(=O)c2[nH]c(cc2-c2ccc(O)cc2)-c2ccoc2)cc1
Show InChI InChI=1S/C23H19N3O5/c27-18-7-5-15(6-8-18)19-11-20(17-9-10-31-13-17)25-21(19)23(29)24-12-14-1-3-16(4-2-14)22(28)26-30/h1-11,13,25,27,30H,12H2,(H,24,29)(H,26,28)
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4.40 -48.5n/an/an/an/an/a6.030



Ube Industries, Ltd.

US Patent


Assay Description
Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...


US Patent US8685986 (2014)


BindingDB Entry DOI: 10.7270/Q28S4NK1
More data for this
Ligand-Target Pair
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