Found 130 hits Enz. Inhib. hit(s) with Target = 'Protein arginine N-methyltransferase 3' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Protein arginine methyltransferase 3 (PRMT3)
(Homo sapiens (Human)) | BDBM178103
 (MS023 (Compound 3) | N1-((4-(4-isopropoxyphenyl)-1...)Show InChI InChI=1S/C17H25N3O/c1-13(2)21-16-6-4-14(5-7-16)17-11-19-10-15(17)12-20(3)9-8-18/h4-7,10-11,13,19H,8-9,12,18H2,1-3H3 | PDB
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PC cid PC sid PDB UniChem
| Article PubMed
| 55 | n/a | 119 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Toronto
| Assay Description In brief, the tritiated S-adenosyl-L-methionine (3HSAM, PerkinElmer Life Sciences) was used as the donor of methyl group. The (3H) methylated biotin ... |
ACS Chem Biol 11: 772-81 (2016)
Article DOI: 10.1021/acschembio.5b00839 BindingDB Entry DOI: 10.7270/Q2765D4H |
More data for this Ligand-Target Pair | |
Protein arginine methyltransferase 3 (PRMT3)
(Homo sapiens (Human)) | BDBM178102
 (N1-Methyl-N1-((4-(3-(trifluoromethyl)phenyl)-1H-py...)Show InChI InChI=1S/C15H18F3N3/c1-21(6-5-19)10-12-8-20-9-14(12)11-3-2-4-13(7-11)15(16,17)18/h2-4,7-9,20H,5-6,10,19H2,1H3 | PDB
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| PC cid PC sid UniChem
| Article PubMed
| 550 | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Toronto
| Assay Description In brief, the tritiated S-adenosyl-L-methionine (3HSAM, PerkinElmer Life Sciences) was used as the donor of methyl group. The (3H) methylated biotin ... |
ACS Chem Biol 11: 772-81 (2016)
Article DOI: 10.1021/acschembio.5b00839 BindingDB Entry DOI: 10.7270/Q2765D4H |
More data for this Ligand-Target Pair | |
Protein arginine methyltransferase 3 (PRMT3)
(Homo sapiens (Human)) | BDBM50431676
 (CHEMBL2349526)Show SMILES N[C@@H](CCSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cc(Br)c2c(N)ncnc12)C(O)=O |r| Show InChI InChI=1S/C15H20BrN5O5S/c16-6-3-21(13-9(6)12(18)19-5-20-13)14-11(23)10(22)8(26-14)4-27-2-1-7(17)15(24)25/h3,5,7-8,10-11,14,22-23H,1-2,4,17H2,(H,24,25)(H2,18,19,20)/t7-,8+,10+,11+,14+/m0/s1 | PDB
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| CHEMBL MMDB PC cid PC sid PDB UniChem
| Article PubMed
| 1.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
EntreMed Inc.
Curated by ChEMBL
| Assay Description Inhibition of PRMT3 (unknown origin) using [3H]SAM assessed as inhibition of biotinylated-H4 (1 to 24 amino acid residues) methylation after 1 hr by ... |
Bioorg Med Chem 21: 1787-94 (2013)
Article DOI: 10.1016/j.bmc.2013.01.049 BindingDB Entry DOI: 10.7270/Q24F1S41 |
More data for this Ligand-Target Pair | |
Protein arginine methyltransferase 3 (PRMT3)
(Homo sapiens (Human)) | BDBM178101
 (N1-Methyl-N1-((5-(3-(trifluoromethyl)phenyl)-2H-1,...)Show InChI InChI=1S/C13H16F3N5/c1-21(6-5-17)8-11-12(19-20-18-11)9-3-2-4-10(7-9)13(14,15)16/h2-4,7H,5-6,8,17H2,1H3,(H,18,19,20) | PDB
B.MOAD GoogleScholar AffyNet 
| PC cid PC sid UniChem
| Article PubMed
| >5.00E+4 | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Toronto
| Assay Description In brief, the tritiated S-adenosyl-L-methionine (3HSAM, PerkinElmer Life Sciences) was used as the donor of methyl group. The (3H) methylated biotin ... |
ACS Chem Biol 11: 772-81 (2016)
Article DOI: 10.1021/acschembio.5b00839 BindingDB Entry DOI: 10.7270/Q2765D4H |
More data for this Ligand-Target Pair | |
Protein arginine N-methyltransferase 3
(Homo sapiens (Human)) | BDBM178103
 (MS023 (Compound 3) | N1-((4-(4-isopropoxyphenyl)-1...)Show InChI InChI=1S/C17H25N3O/c1-13(2)21-16-6-4-14(5-7-16)17-11-19-10-15(17)12-20(3)9-8-18/h4-7,10-11,13,19H,8-9,12,18H2,1-3H3 | PDB
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| Article PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
| Assay Description Inhibition of human PRMT3 assessed as inhibition of methylation activity using biotin-labeled peptide as substrate and [3H]-SAM by scintillation prox... |
J Med Chem 59: 9124-9139 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01033 BindingDB Entry DOI: 10.7270/Q2028TGJ |
More data for this Ligand-Target Pair | |
Protein arginine N-methyltransferase 3
(Homo sapiens) | BDBM50247381
 (CHEMBL4079503) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
| |
J Med Chem 61: 1204-1217 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01674 |
More data for this Ligand-Target Pair | |
Protein arginine N-methyltransferase 3
(Homo sapiens) | BDBM50247397
 (CHEMBL4076640) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
| |
J Med Chem 61: 1204-1217 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01674 |
More data for this Ligand-Target Pair | |
Protein arginine N-methyltransferase 3
(Homo sapiens) | BDBM50247361
 (CHEMBL4077534) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
| |
J Med Chem 61: 1204-1217 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01674 |
More data for this Ligand-Target Pair | |
Protein arginine N-methyltransferase 3
(Homo sapiens) | BDBM50247349
 (CHEMBL4072005) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| PC cid PC sid PDB UniChem
| Article PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
| |
J Med Chem 61: 1204-1217 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01674 |
More data for this Ligand-Target Pair | |
Protein arginine N-methyltransferase 3
(Homo sapiens) | BDBM50247380
 (CHEMBL4061429) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
| |
J Med Chem 61: 1204-1217 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01674 |
More data for this Ligand-Target Pair | |
Protein arginine N-methyltransferase 3
(Homo sapiens) | BDBM50247358
 (CHEMBL4071410) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
| |
J Med Chem 61: 1204-1217 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01674 |
More data for this Ligand-Target Pair | |
Protein arginine N-methyltransferase 3
(Homo sapiens) | BDBM50243294
 (CHEMBL4094513) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhejiang Sci-Tech University
Curated by ChEMBL
| |
J Med Chem 60: 8888-8905 (2017)
Article DOI: 10.1021/acs.jmedchem.7b01134 |
More data for this Ligand-Target Pair | |
Protein arginine N-methyltransferase 3
(Homo sapiens) | BDBM50247362
 (CHEMBL4061085) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
| |
J Med Chem 61: 1204-1217 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01674 |
More data for this Ligand-Target Pair | |
Protein arginine N-methyltransferase 3
(Homo sapiens) | BDBM50247359
 (CHEMBL4062783) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
| |
J Med Chem 61: 1204-1217 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01674 |
More data for this Ligand-Target Pair | |
Protein arginine N-methyltransferase 3
(Homo sapiens) | BDBM50247348
 (CHEMBL4086964) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
| |
J Med Chem 61: 1204-1217 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01674 |
More data for this Ligand-Target Pair | |
Protein arginine N-methyltransferase 3
(Homo sapiens) | BDBM50247360
 (CHEMBL4095787) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
| |
J Med Chem 61: 1204-1217 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01674 |
More data for this Ligand-Target Pair | |
Protein arginine N-methyltransferase 3
(Homo sapiens) | BDBM50247363
 (CHEMBL4082966) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
| |
J Med Chem 61: 1204-1217 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01674 |
More data for this Ligand-Target Pair | |
Protein arginine N-methyltransferase 3
(Homo sapiens) | BDBM50247373
 (CHEMBL4105488) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
| |
J Med Chem 61: 1204-1217 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01674 |
More data for this Ligand-Target Pair | |
Protein arginine N-methyltransferase 3
(Homo sapiens) | BDBM50247350
 (CHEMBL4097428) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 61 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
| |
J Med Chem 61: 1204-1217 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01674 |
More data for this Ligand-Target Pair | |
Protein arginine N-methyltransferase 3
(Homo sapiens) | BDBM50247357
 (CHEMBL4087094) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 84 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
| |
J Med Chem 61: 1204-1217 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01674 |
More data for this Ligand-Target Pair | |
Protein arginine N-methyltransferase 3
(Homo sapiens) | BDBM50247403
 (CHEMBL4082359) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 87 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
| |
J Med Chem 61: 1204-1217 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01674 |
More data for this Ligand-Target Pair | |
Protein arginine N-methyltransferase 3
(Homo sapiens) | BDBM50247349
 (CHEMBL4072005) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| PC cid PC sid PDB UniChem
| Article PubMed
| n/a | n/a | 91 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
| |
J Med Chem 61: 1204-1217 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01674 |
More data for this Ligand-Target Pair | |
Protein arginine N-methyltransferase 3
(Homo sapiens) | BDBM50247378
 (CHEMBL4065941) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 114 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
| |
J Med Chem 61: 1204-1217 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01674 |
More data for this Ligand-Target Pair | |
Protein arginine N-methyltransferase 3
(Homo sapiens) | BDBM50247361
 (CHEMBL4077534) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 134 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
| |
J Med Chem 61: 1204-1217 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01674 |
More data for this Ligand-Target Pair | |
Protein arginine N-methyltransferase 3
(Homo sapiens) | BDBM50427787
 (CHEMBL2325198)Show InChI InChI=1S/C14H17N5O2S/c20-13(19-6-2-1-3-7-19)9-15-14(21)16-10-4-5-11-12(8-10)22-18-17-11/h4-5,8H,1-3,6-7,9H2,(H2,15,16,21) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| Purchase
CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 134 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
| |
J Med Chem 61: 1204-1217 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01674 |
More data for this Ligand-Target Pair | |
Protein arginine N-methyltransferase 3
(Homo sapiens) | BDBM50247358
 (CHEMBL4071410) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 134 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
| |
J Med Chem 61: 1204-1217 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01674 |
More data for this Ligand-Target Pair | |
Protein arginine N-methyltransferase 3
(Homo sapiens) | BDBM50247384
 (CHEMBL4090733) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
| |
J Med Chem 61: 1204-1217 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01674 |
More data for this Ligand-Target Pair | |
Protein arginine N-methyltransferase 3
(Homo sapiens) | BDBM50247375
 (CHEMBL4074611) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 158 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
| |
J Med Chem 61: 1204-1217 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01674 |
More data for this Ligand-Target Pair | |
Protein arginine N-methyltransferase 3
(Homo sapiens) | BDBM50247383
 (CHEMBL4097411) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 166 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
| |
J Med Chem 61: 1204-1217 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01674 |
More data for this Ligand-Target Pair | |
Protein arginine N-methyltransferase 3
(Homo sapiens) | BDBM50247382
 (CHEMBL4059940) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 194 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
| |
J Med Chem 61: 1204-1217 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01674 |
More data for this Ligand-Target Pair | |
Protein arginine N-methyltransferase 3
(Homo sapiens) | BDBM50247349
 (CHEMBL4072005) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| PC cid PC sid PDB UniChem
| Article PubMed
| n/a | n/a | 225 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
| |
J Med Chem 61: 1204-1217 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01674 |
More data for this Ligand-Target Pair | |
Protein arginine methyltransferase 3 (PRMT3)
(Homo sapiens (Human)) | BDBM50427787
 (CHEMBL2325198)Show InChI InChI=1S/C14H17N5O2S/c20-13(19-6-2-1-3-7-19)9-15-14(21)16-10-4-5-11-12(8-10)22-18-17-11/h4-5,8H,1-3,6-7,9H2,(H2,15,16,21) | PDB
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CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill
Curated by ChEMBL
| Assay Description Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos... |
J Med Chem 56: 2110-24 (2013)
Article DOI: 10.1021/jm3018332 BindingDB Entry DOI: 10.7270/Q2W95BHJ |
More data for this Ligand-Target Pair | |
Protein arginine N-methyltransferase 3
(Homo sapiens) | BDBM50247359
 (CHEMBL4062783) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
| |
J Med Chem 61: 1204-1217 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01674 |
More data for this Ligand-Target Pair | |
Protein arginine N-methyltransferase 3
(Homo sapiens) | BDBM50247398
 (CHEMBL4101037) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| PC cid PC sid PDB UniChem
| Article PubMed
| n/a | n/a | 291 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
| |
J Med Chem 61: 1204-1217 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01674 |
More data for this Ligand-Target Pair | |
Protein arginine N-methyltransferase 3
(Homo sapiens) | BDBM50247402
 (CHEMBL4063230) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 292 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
| |
J Med Chem 61: 1204-1217 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01674 |
More data for this Ligand-Target Pair | |
Protein arginine N-methyltransferase 3
(Homo sapiens) | BDBM50247353
 (CHEMBL4081032) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 295 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
| |
J Med Chem 61: 1204-1217 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01674 |
More data for this Ligand-Target Pair | |
Protein arginine methyltransferase 3 (PRMT3)
(Homo sapiens (Human)) | BDBM50427778
 (CHEMBL2325177)Show SMILES [O-][N+](=O)c1ccc(CNC(=O)Nc2ccc3nnsc3c2)cc1 Show InChI InChI=1S/C14H11N5O3S/c20-14(15-8-9-1-4-11(5-2-9)19(21)22)16-10-3-6-12-13(7-10)23-18-17-12/h1-7H,8H2,(H2,15,16,20) | PDB
B.MOAD GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill
Curated by ChEMBL
| Assay Description Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos... |
J Med Chem 56: 2110-24 (2013)
Article DOI: 10.1021/jm3018332 BindingDB Entry DOI: 10.7270/Q2W95BHJ |
More data for this Ligand-Target Pair | |
Protein arginine methyltransferase 3 (PRMT3)
(Homo sapiens (Human)) | BDBM50427788
 (CHEMBL2325197)Show InChI InChI=1S/C15H11FN4O2S/c16-10-3-1-9(2-4-10)13(21)8-17-15(22)18-11-5-6-12-14(7-11)23-20-19-12/h1-7H,8H2,(H2,17,18,22) | PDB
B.MOAD GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 360 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill
Curated by ChEMBL
| Assay Description Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos... |
J Med Chem 56: 2110-24 (2013)
Article DOI: 10.1021/jm3018332 BindingDB Entry DOI: 10.7270/Q2W95BHJ |
More data for this Ligand-Target Pair | |
Protein arginine N-methyltransferase 3
(Homo sapiens) | BDBM50247354
 (CHEMBL4104833) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 421 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
| |
J Med Chem 61: 1204-1217 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01674 |
More data for this Ligand-Target Pair | |
Protein arginine N-methyltransferase 3
(Homo sapiens) | BDBM50247377
 (CHEMBL4100373) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 476 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
| |
J Med Chem 61: 1204-1217 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01674 |
More data for this Ligand-Target Pair | |
Protein arginine N-methyltransferase 3
(Homo sapiens) | BDBM50247374
 (CHEMBL4084879) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 477 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
| |
J Med Chem 61: 1204-1217 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01674 |
More data for this Ligand-Target Pair | |
Protein arginine methyltransferase 3 (PRMT3)
(Homo sapiens (Human)) | BDBM50427772
 (CHEMBL2325183)Show InChI InChI=1S/C15H12N4O2S/c20-13(10-4-2-1-3-5-10)9-16-15(21)17-11-6-7-12-14(8-11)22-19-18-12/h1-8H,9H2,(H2,16,17,21) | PDB
B.MOAD GoogleScholar AffyNet 
| CHEMBL MMDB PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 480 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill
Curated by ChEMBL
| Assay Description Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos... |
J Med Chem 56: 2110-24 (2013)
Article DOI: 10.1021/jm3018332 BindingDB Entry DOI: 10.7270/Q2W95BHJ |
More data for this Ligand-Target Pair |  3D Structure (crystal) |
Protein arginine methyltransferase 3 (PRMT3)
(Homo sapiens (Human)) | BDBM50427790
 (CHEMBL2325195)Show InChI InChI=1S/C15H20N4O2S/c20-13(10-4-2-1-3-5-10)9-16-15(21)17-11-6-7-12-14(8-11)22-19-18-12/h6-8,10,13,20H,1-5,9H2,(H2,16,17,21) | PDB
B.MOAD GoogleScholar AffyNet 
| CHEMBL KEGG PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 490 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill
Curated by ChEMBL
| Assay Description Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos... |
J Med Chem 56: 2110-24 (2013)
Article DOI: 10.1021/jm3018332 BindingDB Entry DOI: 10.7270/Q2W95BHJ |
More data for this Ligand-Target Pair | |
Protein arginine N-methyltransferase 3
(Homo sapiens) | BDBM50247399
 (CHEMBL4099065) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 540 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
| |
J Med Chem 61: 1204-1217 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01674 |
More data for this Ligand-Target Pair | |
Protein arginine N-methyltransferase 3
(Homo sapiens) | BDBM50247400
 (CHEMBL4090682) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 757 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
| |
J Med Chem 61: 1204-1217 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01674 |
More data for this Ligand-Target Pair | |
Protein arginine N-methyltransferase 3
(Homo sapiens) | BDBM50247351
 (CHEMBL4067331) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 833 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
| |
J Med Chem 61: 1204-1217 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01674 |
More data for this Ligand-Target Pair | |
Protein arginine methyltransferase 3 (PRMT3)
(Homo sapiens (Human)) | BDBM50427789
 (CHEMBL2325196)Show InChI InChI=1S/C15H18N4O2S/c20-13(10-4-2-1-3-5-10)9-16-15(21)17-11-6-7-12-14(8-11)22-19-18-12/h6-8,10H,1-5,9H2,(H2,16,17,21) | PDB
B.MOAD GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 840 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill
Curated by ChEMBL
| Assay Description Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos... |
J Med Chem 56: 2110-24 (2013)
Article DOI: 10.1021/jm3018332 BindingDB Entry DOI: 10.7270/Q2W95BHJ |
More data for this Ligand-Target Pair | |
Protein arginine methyltransferase 3 (PRMT3)
(Homo sapiens (Human)) | BDBM50427777
 (CHEMBL2325178)Show InChI InChI=1S/C15H14N4O3S2/c1-24(21,22)12-5-2-10(3-6-12)9-16-15(20)17-11-4-7-13-14(8-11)23-19-18-13/h2-8H,9H2,1H3,(H2,16,17,20) | PDB
B.MOAD GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 850 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill
Curated by ChEMBL
| Assay Description Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos... |
J Med Chem 56: 2110-24 (2013)
Article DOI: 10.1021/jm3018332 BindingDB Entry DOI: 10.7270/Q2W95BHJ |
More data for this Ligand-Target Pair | |
Protein arginine N-methyltransferase 3
(Homo sapiens) | BDBM50247356
 (CHEMBL4068520) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet 
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 967 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
| |
J Med Chem 61: 1204-1217 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01674 |
More data for this Ligand-Target Pair | |
Protein arginine methyltransferase 3 (PRMT3)
(Homo sapiens (Human)) | BDBM50427767
 (CHEMBL2325442)Show InChI InChI=1S/C15H20N4OS/c20-15(16-9-8-11-4-2-1-3-5-11)17-12-6-7-13-14(10-12)21-19-18-13/h6-7,10-11H,1-5,8-9H2,(H2,16,17,20) | PDB
B.MOAD GoogleScholar AffyNet 
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill
Curated by ChEMBL
| Assay Description Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos... |
J Med Chem 56: 2110-24 (2013)
Article DOI: 10.1021/jm3018332 BindingDB Entry DOI: 10.7270/Q2W95BHJ |
More data for this Ligand-Target Pair | |