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Compile Data Set for Download or QSAR

Found 130 hits Enz. Inhib. hit(s) with Target = 'Protein arginine N-methyltransferase 3'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM178103
PNG
(MS023 (Compound 3) | N1-((4-(4-isopropoxyphenyl)-1...)
Show SMILES CC(C)Oc1ccc(cc1)-c1c[nH]cc1CN(C)CCN
Show InChI InChI=1S/C17H25N3O/c1-13(2)21-16-6-4-14(5-7-16)17-11-19-10-15(17)12-20(3)9-8-18/h4-7,10-11,13,19H,8-9,12,18H2,1-3H3
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55n/a 119n/an/an/an/an/an/a



University of Toronto



Assay Description
In brief, the tritiated S-adenosyl-L-methionine (3HSAM, PerkinElmer Life Sciences) was used as the donor of methyl group. The (3H) methylated biotin ...


ACS Chem Biol 11: 772-81 (2016)


Article DOI: 10.1021/acschembio.5b00839
BindingDB Entry DOI: 10.7270/Q2765D4H
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM178102
PNG
(N1-Methyl-N1-((4-(3-(trifluoromethyl)phenyl)-1H-py...)
Show SMILES CN(CCN)Cc1c[nH]cc1-c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C15H18F3N3/c1-21(6-5-19)10-12-8-20-9-14(12)11-3-2-4-13(7-11)15(16,17)18/h2-4,7-9,20H,5-6,10,19H2,1H3
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550n/a 1.10E+3n/an/an/an/an/an/a



University of Toronto



Assay Description
In brief, the tritiated S-adenosyl-L-methionine (3HSAM, PerkinElmer Life Sciences) was used as the donor of methyl group. The (3H) methylated biotin ...


ACS Chem Biol 11: 772-81 (2016)


Article DOI: 10.1021/acschembio.5b00839
BindingDB Entry DOI: 10.7270/Q2765D4H
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50431676
PNG
(CHEMBL2349526)
Show SMILES N[C@@H](CCSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cc(Br)c2c(N)ncnc12)C(O)=O |r|
Show InChI InChI=1S/C15H20BrN5O5S/c16-6-3-21(13-9(6)12(18)19-5-20-13)14-11(23)10(22)8(26-14)4-27-2-1-7(17)15(24)25/h3,5,7-8,10-11,14,22-23H,1-2,4,17H2,(H,24,25)(H2,18,19,20)/t7-,8+,10+,11+,14+/m0/s1
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1.15E+3n/an/an/an/an/an/an/an/a



EntreMed Inc.

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using [3H]SAM assessed as inhibition of biotinylated-H4 (1 to 24 amino acid residues) methylation after 1 hr by ...


Bioorg Med Chem 21: 1787-94 (2013)


Article DOI: 10.1016/j.bmc.2013.01.049
BindingDB Entry DOI: 10.7270/Q24F1S41
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM178101
PNG
(N1-Methyl-N1-((5-(3-(trifluoromethyl)phenyl)-2H-1,...)
Show SMILES CN(CCN)Cc1n[nH]nc1-c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C13H16F3N5/c1-21(6-5-17)8-11-12(19-20-18-11)9-3-2-4-10(7-9)13(14,15)16/h2-4,7H,5-6,8,17H2,1H3,(H,18,19,20)
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>5.00E+4n/a>1.00E+5n/an/an/an/an/an/a



University of Toronto



Assay Description
In brief, the tritiated S-adenosyl-L-methionine (3HSAM, PerkinElmer Life Sciences) was used as the donor of methyl group. The (3H) methylated biotin ...


ACS Chem Biol 11: 772-81 (2016)


Article DOI: 10.1021/acschembio.5b00839
BindingDB Entry DOI: 10.7270/Q2765D4H
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 3


(Homo sapiens (Human))
BDBM178103
PNG
(MS023 (Compound 3) | N1-((4-(4-isopropoxyphenyl)-1...)
Show SMILES CC(C)Oc1ccc(cc1)-c1c[nH]cc1CN(C)CCN
Show InChI InChI=1S/C17H25N3O/c1-13(2)21-16-6-4-14(5-7-16)17-11-19-10-15(17)12-20(3)9-8-18/h4-7,10-11,13,19H,8-9,12,18H2,1-3H3
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n/an/a 4n/an/an/an/an/an/a



Icahn School of Medicine at Mount Sinai

Curated by ChEMBL


Assay Description
Inhibition of human PRMT3 assessed as inhibition of methylation activity using biotin-labeled peptide as substrate and [3H]-SAM by scintillation prox...


J Med Chem 59: 9124-9139 (2016)


Article DOI: 10.1021/acs.jmedchem.6b01033
BindingDB Entry DOI: 10.7270/Q2028TGJ
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 3


(Homo sapiens)
BDBM50247381
PNG
(CHEMBL4079503)
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n/an/a 10n/an/an/an/an/an/a



Icahn School of Medicine at Mount Sinai

Curated by ChEMBL




J Med Chem 61: 1204-1217 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01674
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 3


(Homo sapiens)
BDBM50247397
PNG
(CHEMBL4076640)
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n/an/a 17n/an/an/an/an/an/a



Icahn School of Medicine at Mount Sinai

Curated by ChEMBL




J Med Chem 61: 1204-1217 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01674
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 3


(Homo sapiens)
BDBM50247361
PNG
(CHEMBL4077534)
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n/an/a 19n/an/an/an/an/an/a



Icahn School of Medicine at Mount Sinai

Curated by ChEMBL




J Med Chem 61: 1204-1217 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01674
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 3


(Homo sapiens)
BDBM50247349
PNG
(CHEMBL4072005)
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n/an/a 19n/an/an/an/an/an/a



Icahn School of Medicine at Mount Sinai

Curated by ChEMBL




J Med Chem 61: 1204-1217 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01674
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 3


(Homo sapiens)
BDBM50247380
PNG
(CHEMBL4061429)
UniProtKB/SwissProt

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n/an/a 19n/an/an/an/an/an/a



Icahn School of Medicine at Mount Sinai

Curated by ChEMBL




J Med Chem 61: 1204-1217 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01674
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 3


(Homo sapiens)
BDBM50247358
PNG
(CHEMBL4071410)
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n/an/a 22n/an/an/an/an/an/a



Icahn School of Medicine at Mount Sinai

Curated by ChEMBL




J Med Chem 61: 1204-1217 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01674
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 3


(Homo sapiens)
BDBM50243294
PNG
(CHEMBL4094513)
UniProtKB/SwissProt

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n/an/a 22n/an/an/an/an/an/a



Zhejiang Sci-Tech University

Curated by ChEMBL




J Med Chem 60: 8888-8905 (2017)


Article DOI: 10.1021/acs.jmedchem.7b01134
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 3


(Homo sapiens)
BDBM50247362
PNG
(CHEMBL4061085)
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n/an/a 22n/an/an/an/an/an/a



Icahn School of Medicine at Mount Sinai

Curated by ChEMBL




J Med Chem 61: 1204-1217 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01674
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 3


(Homo sapiens)
BDBM50247359
PNG
(CHEMBL4062783)
UniProtKB/SwissProt

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n/an/a 24n/an/an/an/an/an/a



Icahn School of Medicine at Mount Sinai

Curated by ChEMBL




J Med Chem 61: 1204-1217 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01674
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 3


(Homo sapiens)
BDBM50247348
PNG
(CHEMBL4086964)
UniProtKB/SwissProt

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n/an/a 35n/an/an/an/an/an/a



Icahn School of Medicine at Mount Sinai

Curated by ChEMBL




J Med Chem 61: 1204-1217 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01674
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 3


(Homo sapiens)
BDBM50247360
PNG
(CHEMBL4095787)
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n/an/a 36n/an/an/an/an/an/a



Icahn School of Medicine at Mount Sinai

Curated by ChEMBL




J Med Chem 61: 1204-1217 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01674
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 3


(Homo sapiens)
BDBM50247363
PNG
(CHEMBL4082966)
UniProtKB/SwissProt

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n/an/a 46n/an/an/an/an/an/a



Icahn School of Medicine at Mount Sinai

Curated by ChEMBL




J Med Chem 61: 1204-1217 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01674
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 3


(Homo sapiens)
BDBM50247373
PNG
(CHEMBL4105488)
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n/an/a 55n/an/an/an/an/an/a



Icahn School of Medicine at Mount Sinai

Curated by ChEMBL




J Med Chem 61: 1204-1217 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01674
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 3


(Homo sapiens)
BDBM50247350
PNG
(CHEMBL4097428)
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n/an/a 61n/an/an/an/an/an/a



Icahn School of Medicine at Mount Sinai

Curated by ChEMBL




J Med Chem 61: 1204-1217 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01674
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 3


(Homo sapiens)
BDBM50247357
PNG
(CHEMBL4087094)
UniProtKB/SwissProt

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n/an/a 84n/an/an/an/an/an/a



Icahn School of Medicine at Mount Sinai

Curated by ChEMBL




J Med Chem 61: 1204-1217 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01674
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 3


(Homo sapiens)
BDBM50247403
PNG
(CHEMBL4082359)
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n/an/a 87n/an/an/an/an/an/a



Icahn School of Medicine at Mount Sinai

Curated by ChEMBL




J Med Chem 61: 1204-1217 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01674
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 3


(Homo sapiens)
BDBM50247349
PNG
(CHEMBL4072005)
UniProtKB/SwissProt

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n/an/a 91n/an/an/an/an/an/a



Icahn School of Medicine at Mount Sinai

Curated by ChEMBL




J Med Chem 61: 1204-1217 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01674
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 3


(Homo sapiens)
BDBM50247378
PNG
(CHEMBL4065941)
UniProtKB/SwissProt

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n/an/a 114n/an/an/an/an/an/a



Icahn School of Medicine at Mount Sinai

Curated by ChEMBL




J Med Chem 61: 1204-1217 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01674
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 3


(Homo sapiens)
BDBM50247361
PNG
(CHEMBL4077534)
UniProtKB/SwissProt

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n/an/a 134n/an/an/an/an/an/a



Icahn School of Medicine at Mount Sinai

Curated by ChEMBL




J Med Chem 61: 1204-1217 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01674
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 3


(Homo sapiens)
BDBM50427787
PNG
(CHEMBL2325198)
Show SMILES O=C(NCC(=O)N1CCCCC1)Nc1ccc2nnsc2c1
Show InChI InChI=1S/C14H17N5O2S/c20-13(19-6-2-1-3-7-19)9-15-14(21)16-10-4-5-11-12(8-10)22-18-17-11/h4-5,8H,1-3,6-7,9H2,(H2,15,16,21)
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n/an/a 134n/an/an/an/an/an/a



Icahn School of Medicine at Mount Sinai

Curated by ChEMBL




J Med Chem 61: 1204-1217 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01674
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 3


(Homo sapiens)
BDBM50247358
PNG
(CHEMBL4071410)
UniProtKB/SwissProt

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n/an/a 134n/an/an/an/an/an/a



Icahn School of Medicine at Mount Sinai

Curated by ChEMBL




J Med Chem 61: 1204-1217 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01674
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 3


(Homo sapiens)
BDBM50247384
PNG
(CHEMBL4090733)
UniProtKB/SwissProt

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n/an/a 150n/an/an/an/an/an/a



Icahn School of Medicine at Mount Sinai

Curated by ChEMBL




J Med Chem 61: 1204-1217 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01674
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 3


(Homo sapiens)
BDBM50247375
PNG
(CHEMBL4074611)
UniProtKB/SwissProt

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n/an/a 158n/an/an/an/an/an/a



Icahn School of Medicine at Mount Sinai

Curated by ChEMBL




J Med Chem 61: 1204-1217 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01674
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 3


(Homo sapiens)
BDBM50247383
PNG
(CHEMBL4097411)
UniProtKB/SwissProt

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n/an/a 166n/an/an/an/an/an/a



Icahn School of Medicine at Mount Sinai

Curated by ChEMBL




J Med Chem 61: 1204-1217 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01674
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 3


(Homo sapiens)
BDBM50247382
PNG
(CHEMBL4059940)
UniProtKB/SwissProt

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n/an/a 194n/an/an/an/an/an/a



Icahn School of Medicine at Mount Sinai

Curated by ChEMBL




J Med Chem 61: 1204-1217 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01674
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 3


(Homo sapiens)
BDBM50247349
PNG
(CHEMBL4072005)
UniProtKB/SwissProt

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n/an/a 225n/an/an/an/an/an/a



Icahn School of Medicine at Mount Sinai

Curated by ChEMBL




J Med Chem 61: 1204-1217 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01674
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427787
PNG
(CHEMBL2325198)
Show SMILES O=C(NCC(=O)N1CCCCC1)Nc1ccc2nnsc2c1
Show InChI InChI=1S/C14H17N5O2S/c20-13(19-6-2-1-3-7-19)9-15-14(21)16-10-4-5-11-12(8-10)22-18-17-11/h4-5,8H,1-3,6-7,9H2,(H2,15,16,21)
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n/an/a 230n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 3


(Homo sapiens)
BDBM50247359
PNG
(CHEMBL4062783)
UniProtKB/SwissProt

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n/an/a 240n/an/an/an/an/an/a



Icahn School of Medicine at Mount Sinai

Curated by ChEMBL




J Med Chem 61: 1204-1217 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01674
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 3


(Homo sapiens)
BDBM50247398
PNG
(CHEMBL4101037)
UniProtKB/SwissProt

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n/an/a 291n/an/an/an/an/an/a



Icahn School of Medicine at Mount Sinai

Curated by ChEMBL




J Med Chem 61: 1204-1217 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01674
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 3


(Homo sapiens)
BDBM50247402
PNG
(CHEMBL4063230)
UniProtKB/SwissProt

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n/an/a 292n/an/an/an/an/an/a



Icahn School of Medicine at Mount Sinai

Curated by ChEMBL




J Med Chem 61: 1204-1217 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01674
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 3


(Homo sapiens)
BDBM50247353
PNG
(CHEMBL4081032)
UniProtKB/SwissProt

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n/an/a 295n/an/an/an/an/an/a



Icahn School of Medicine at Mount Sinai

Curated by ChEMBL




J Med Chem 61: 1204-1217 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01674
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427778
PNG
(CHEMBL2325177)
Show SMILES [O-][N+](=O)c1ccc(CNC(=O)Nc2ccc3nnsc3c2)cc1
Show InChI InChI=1S/C14H11N5O3S/c20-14(15-8-9-1-4-11(5-2-9)19(21)22)16-10-3-6-12-13(7-10)23-18-17-12/h1-7H,8H2,(H2,15,16,20)
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n/an/a 300n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427788
PNG
(CHEMBL2325197)
Show SMILES Fc1ccc(cc1)C(=O)CNC(=O)Nc1ccc2nnsc2c1
Show InChI InChI=1S/C15H11FN4O2S/c16-10-3-1-9(2-4-10)13(21)8-17-15(22)18-11-5-6-12-14(7-11)23-20-19-12/h1-7H,8H2,(H2,17,18,22)
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n/an/a 360n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 3


(Homo sapiens)
BDBM50247354
PNG
(CHEMBL4104833)
UniProtKB/SwissProt

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Article
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n/an/a 421n/an/an/an/an/an/a



Icahn School of Medicine at Mount Sinai

Curated by ChEMBL




J Med Chem 61: 1204-1217 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01674
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 3


(Homo sapiens)
BDBM50247377
PNG
(CHEMBL4100373)
UniProtKB/SwissProt

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n/an/a 476n/an/an/an/an/an/a



Icahn School of Medicine at Mount Sinai

Curated by ChEMBL




J Med Chem 61: 1204-1217 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01674
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 3


(Homo sapiens)
BDBM50247374
PNG
(CHEMBL4084879)
UniProtKB/SwissProt

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UniChem
Article
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n/an/a 477n/an/an/an/an/an/a



Icahn School of Medicine at Mount Sinai

Curated by ChEMBL




J Med Chem 61: 1204-1217 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01674
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427772
PNG
(CHEMBL2325183)
Show SMILES O=C(NCC(=O)c1ccccc1)Nc1ccc2nnsc2c1
Show InChI InChI=1S/C15H12N4O2S/c20-13(10-4-2-1-3-5-10)9-16-15(21)17-11-6-7-12-14(8-11)22-19-18-12/h1-8H,9H2,(H2,16,17,21)
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n/an/a 480n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427790
PNG
(CHEMBL2325195)
Show SMILES OC(CNC(=O)Nc1ccc2nnsc2c1)C1CCCCC1
Show InChI InChI=1S/C15H20N4O2S/c20-13(10-4-2-1-3-5-10)9-16-15(21)17-11-6-7-12-14(8-11)22-19-18-12/h6-8,10,13,20H,1-5,9H2,(H2,16,17,21)
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n/an/a 490n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 3


(Homo sapiens)
BDBM50247399
PNG
(CHEMBL4099065)
UniProtKB/SwissProt

antibodypedia
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UniChem
Article
PubMed
n/an/a 540n/an/an/an/an/an/a



Icahn School of Medicine at Mount Sinai

Curated by ChEMBL




J Med Chem 61: 1204-1217 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01674
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 3


(Homo sapiens)
BDBM50247400
PNG
(CHEMBL4090682)
UniProtKB/SwissProt

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n/an/a 757n/an/an/an/an/an/a



Icahn School of Medicine at Mount Sinai

Curated by ChEMBL




J Med Chem 61: 1204-1217 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01674
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 3


(Homo sapiens)
BDBM50247351
PNG
(CHEMBL4067331)
UniProtKB/SwissProt

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UniChem
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n/an/a 833n/an/an/an/an/an/a



Icahn School of Medicine at Mount Sinai

Curated by ChEMBL




J Med Chem 61: 1204-1217 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01674
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427789
PNG
(CHEMBL2325196)
Show SMILES O=C(NCC(=O)C1CCCCC1)Nc1ccc2nnsc2c1
Show InChI InChI=1S/C15H18N4O2S/c20-13(10-4-2-1-3-5-10)9-16-15(21)17-11-6-7-12-14(8-11)22-19-18-12/h6-8,10H,1-5,9H2,(H2,16,17,21)
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n/an/a 840n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427777
PNG
(CHEMBL2325178)
Show SMILES CS(=O)(=O)c1ccc(CNC(=O)Nc2ccc3nnsc3c2)cc1
Show InChI InChI=1S/C15H14N4O3S2/c1-24(21,22)12-5-2-10(3-6-12)9-16-15(20)17-11-4-7-13-14(8-11)23-19-18-13/h2-8H,9H2,1H3,(H2,16,17,20)
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n/an/a 850n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
Protein arginine N-methyltransferase 3


(Homo sapiens)
BDBM50247356
PNG
(CHEMBL4068520)
UniProtKB/SwissProt

antibodypedia
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n/an/a 967n/an/an/an/an/an/a



Icahn School of Medicine at Mount Sinai

Curated by ChEMBL




J Med Chem 61: 1204-1217 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01674
More data for this
Ligand-Target Pair
Protein arginine methyltransferase 3 (PRMT3)


(Homo sapiens (Human))
BDBM50427767
PNG
(CHEMBL2325442)
Show SMILES O=C(NCCC1CCCCC1)Nc1ccc2nnsc2c1
Show InChI InChI=1S/C15H20N4OS/c20-15(16-9-8-11-4-2-1-3-5-11)17-12-6-7-13-14(10-12)21-19-18-13/h6-7,10-11H,1-5,8-9H2,(H2,16,17,20)
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n/an/a 1.00E+3n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...


J Med Chem 56: 2110-24 (2013)


Article DOI: 10.1021/jm3018332
BindingDB Entry DOI: 10.7270/Q2W95BHJ
More data for this
Ligand-Target Pair
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