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Compile Data Set for Download or QSAR

Found 575 hits Enz. Inhib. hit(s) with Target = 'Sigma-2'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sigma-2 receptor


(Rattus norvegicus (Rat))
BDBM330349
PNG
(US9724435, Compound CM-366)
Show SMILES Fc1ccc(cc1)-c1ccc2oc(=O)n(CCCCN3CCN(CC3)C3CCCCC3)c2c1
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0.00600n/an/an/an/an/an/an/an/a



THE UNIVERSITY OF MISSISSIPPI; THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY

US Patent




US Patent US9724435 (2017)


BindingDB Entry DOI: 10.7270/Q2BZ6856
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Mus musculus (Mouse))
BDBM312199
PNG
(US9604926, Compound CM-366)
Show SMILES Fc1ccc(cc1)-c1ccc2[nH]c(=O)n(CCCCN3CCN(CC3)C3CCCCC3)c2c1
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0.00600n/an/an/an/an/an/an/an/a



THE UNIVERSITY OF MISSISSIPPI

US Patent




US Patent US9604926 (2017)


BindingDB Entry DOI: 10.7270/Q27D2X6J
More data for this
Ligand-Target Pair
Sigma-2 receptor


(Rattus norvegicus (Rat))
BDBM312198
PNG
(US9604926, Compound CM-365 | US9724435, Compound C...)
Show SMILES Brc1ccc2oc(=O)n(CCCCN3CCN(CC3)C3CCCCC3)c2c1
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0.0550n/an/an/an/an/an/an/an/a



THE UNIVERSITY OF MISSISSIPPI; THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY

US Patent




US Patent US9724435 (2017)


BindingDB Entry DOI: 10.7270/Q2BZ6856
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Mus musculus (Mouse))
BDBM312198
PNG
(US9604926, Compound CM-365 | US9724435, Compound C...)
Show SMILES Brc1ccc2oc(=O)n(CCCCN3CCN(CC3)C3CCCCC3)c2c1
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0.0550n/an/an/an/an/an/an/an/a



THE UNIVERSITY OF MISSISSIPPI

US Patent




US Patent US9604926 (2017)


BindingDB Entry DOI: 10.7270/Q27D2X6J
More data for this
Ligand-Target Pair
Sigma-2 receptor


(Rattus norvegicus (Rat))
BDBM50353847
PNG
(CHEMBL1831157 | US9604926, Compound CM-360 | US972...)
Show SMILES COc1cc2CCN(CCCCn3ccc4ccccc34)Cc2cc1OC
Show InChI InChI=1S/C23H28N2O2/c1-26-22-15-19-9-13-24(17-20(19)16-23(22)27-2)11-5-6-12-25-14-10-18-7-3-4-8-21(18)25/h3-4,7-8,10,14-16H,5-6,9,11-13,17H2,1-2H3
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0.210n/an/an/an/an/an/an/an/a



THE UNIVERSITY OF MISSISSIPPI; THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY

US Patent




US Patent US9724435 (2017)


BindingDB Entry DOI: 10.7270/Q2BZ6856
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Mus musculus (Mouse))
BDBM50353847
PNG
(CHEMBL1831157 | US9604926, Compound CM-360 | US972...)
Show SMILES COc1cc2CCN(CCCCn3ccc4ccccc34)Cc2cc1OC
Show InChI InChI=1S/C23H28N2O2/c1-26-22-15-19-9-13-24(17-20(19)16-23(22)27-2)11-5-6-12-25-14-10-18-7-3-4-8-21(18)25/h3-4,7-8,10,14-16H,5-6,9,11-13,17H2,1-2H3
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0.210n/an/an/an/an/an/an/an/a



THE UNIVERSITY OF MISSISSIPPI

US Patent




US Patent US9604926 (2017)


BindingDB Entry DOI: 10.7270/Q27D2X6J
More data for this
Ligand-Target Pair
Sigma-2 receptor


(Rattus norvegicus (Rat))
BDBM312234
PNG
(US9604926, Compound AZ-68 | US9724435, Compound AZ...)
Show SMILES Fc1ccc2n(CCCCN3CCN(CC3)C3CCCCC3)c(=O)sc2c1
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0.220n/an/an/an/an/an/an/an/a



THE UNIVERSITY OF MISSISSIPPI; THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY

US Patent




US Patent US9724435 (2017)


BindingDB Entry DOI: 10.7270/Q2BZ6856
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Mus musculus (Mouse))
BDBM312234
PNG
(US9604926, Compound AZ-68 | US9724435, Compound AZ...)
Show SMILES Fc1ccc2n(CCCCN3CCN(CC3)C3CCCCC3)c(=O)sc2c1
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0.220n/an/an/an/an/an/an/an/a



THE UNIVERSITY OF MISSISSIPPI

US Patent




US Patent US9604926 (2017)


BindingDB Entry DOI: 10.7270/Q27D2X6J
More data for this
Ligand-Target Pair
Sigma-2 receptor


(Rattus norvegicus (Rat))
BDBM50048866
PNG
(1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydro-na...)
Show SMILES COc1cccc2C(CCCN3CCN(CC3)C3CCCCC3)CCCc12
Show InChI InChI=1S/C24H38N2O/c1-27-24-14-6-12-22-20(8-5-13-23(22)24)9-7-15-25-16-18-26(19-17-25)21-10-3-2-4-11-21/h6,12,14,20-21H,2-5,7-11,13,15-19H2,1H3
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PubMed
0.340n/an/an/an/an/an/an/an/a



Institut f£r Pharmazeutische und Medizinische Chemie der Universit£t M£nster

Curated by ChEMBL




Bioorg Med Chem 25: 4778-4799 (2017)


Article DOI: 10.1016/j.bmc.2017.07.027
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Mus musculus (Mouse))
BDBM50353844
PNG
(CHEMBL270341 | US9604926, Compound CM-145 | US9724...)
Show SMILES O=c1sc2ccccc2n1CCCCN1CCN(CC1)C1CCCCC1
Show InChI InChI=1S/C21H31N3OS/c25-21-24(19-10-4-5-11-20(19)26-21)13-7-6-12-22-14-16-23(17-15-22)18-8-2-1-3-9-18/h4-5,10-11,18H,1-3,6-9,12-17H2
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0.390n/an/an/an/an/an/an/an/a



THE UNIVERSITY OF MISSISSIPPI

US Patent




US Patent US9604926 (2017)


BindingDB Entry DOI: 10.7270/Q27D2X6J
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Mus musculus (Mouse))
BDBM50353844
PNG
(CHEMBL270341 | US9604926, Compound CM-145 | US9724...)
Show SMILES O=c1sc2ccccc2n1CCCCN1CCN(CC1)C1CCCCC1
Show InChI InChI=1S/C21H31N3OS/c25-21-24(19-10-4-5-11-20(19)26-21)13-7-6-12-22-14-16-23(17-15-22)18-8-2-1-3-9-18/h4-5,10-11,18H,1-3,6-9,12-17H2
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0.390n/an/an/an/an/an/an/an/a



THE UNIVERSITY OF MISSISSIPPI

US Patent




US Patent US9604926 (2017)


BindingDB Entry DOI: 10.7270/Q27D2X6J
More data for this
Ligand-Target Pair
Sigma-2 receptor


(Rattus norvegicus (Rat))
BDBM50353844
PNG
(CHEMBL270341 | US9604926, Compound CM-145 | US9724...)
Show SMILES O=c1sc2ccccc2n1CCCCN1CCN(CC1)C1CCCCC1
Show InChI InChI=1S/C21H31N3OS/c25-21-24(19-10-4-5-11-20(19)26-21)13-7-6-12-22-14-16-23(17-15-22)18-8-2-1-3-9-18/h4-5,10-11,18H,1-3,6-9,12-17H2
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0.390n/an/an/an/an/an/an/an/a



THE UNIVERSITY OF MISSISSIPPI; THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY

US Patent




US Patent US9724435 (2017)


BindingDB Entry DOI: 10.7270/Q2BZ6856
More data for this
Ligand-Target Pair
Sigma-2 receptor


(Rattus norvegicus (Rat))
BDBM50353844
PNG
(CHEMBL270341 | US9604926, Compound CM-145 | US9724...)
Show SMILES O=c1sc2ccccc2n1CCCCN1CCN(CC1)C1CCCCC1
Show InChI InChI=1S/C21H31N3OS/c25-21-24(19-10-4-5-11-20(19)26-21)13-7-6-12-22-14-16-23(17-15-22)18-8-2-1-3-9-18/h4-5,10-11,18H,1-3,6-9,12-17H2
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0.390n/an/an/an/an/an/an/an/a



THE UNIVERSITY OF MISSISSIPPI; THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY

US Patent




US Patent US9724435 (2017)


BindingDB Entry DOI: 10.7270/Q2BZ6856
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM349368
PNG
(US10207991, Ex. Cpd. No. 11)
Show SMILES COc1cc2CN(Cc2cc1OC)[C@H](C)CCc1ccc(Cl)c(Cl)c1 |r|
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0.440n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent




US Patent US10207991 (2019)


BindingDB Entry DOI: 10.7270/Q2BV7JRG
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM349368
PNG
(US10207991, Ex. Cpd. No. 11)
Show SMILES COc1cc2CN(Cc2cc1OC)[C@H](C)CCc1ccc(Cl)c(Cl)c1 |r|
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0.440n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent




US Patent US9796672 (2017)


BindingDB Entry DOI: 10.7270/Q2X92DFN
More data for this
Ligand-Target Pair
Sigma-2 receptor


(Rattus norvegicus (Rat))
BDBM312202
PNG
(US9604926, Compound CM-397 | US9724435, Compound C...)
Show SMILES Cn1c2ccccc2n(CCCCN2CCN(CC2)c2ccc(F)cc2)c1=O
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0.460n/an/an/an/an/an/an/an/a



THE UNIVERSITY OF MISSISSIPPI; THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY

US Patent




US Patent US9724435 (2017)


BindingDB Entry DOI: 10.7270/Q2BZ6856
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Mus musculus (Mouse))
BDBM312202
PNG
(US9604926, Compound CM-397 | US9724435, Compound C...)
Show SMILES Cn1c2ccccc2n(CCCCN2CCN(CC2)c2ccc(F)cc2)c1=O
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0.460n/an/an/an/an/an/an/an/a



THE UNIVERSITY OF MISSISSIPPI

US Patent




US Patent US9604926 (2017)


BindingDB Entry DOI: 10.7270/Q27D2X6J
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Mus musculus (Mouse))
BDBM312235
PNG
(US9604926, Compound AZ-78 | US9724435, Compound AZ...)
Show SMILES Fc1ccc2n(CCCCN3CCN(CC3)C3CCCCC3)c(=S)sc2c1
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0.5n/an/an/an/an/an/an/an/a



THE UNIVERSITY OF MISSISSIPPI

US Patent




US Patent US9604926 (2017)


BindingDB Entry DOI: 10.7270/Q27D2X6J
More data for this
Ligand-Target Pair
Sigma-2 receptor


(Rattus norvegicus (Rat))
BDBM312235
PNG
(US9604926, Compound AZ-78 | US9724435, Compound AZ...)
Show SMILES Fc1ccc2n(CCCCN3CCN(CC3)C3CCCCC3)c(=S)sc2c1
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0.5n/an/an/an/an/an/an/an/a



THE UNIVERSITY OF MISSISSIPPI; THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY

US Patent




US Patent US9724435 (2017)


BindingDB Entry DOI: 10.7270/Q2BZ6856
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM349518
PNG
(US10207991, Ex. Cpd. No. 34)
Show SMILES COc1cc2CN(Cc2cc1OC)C(C)(C)CCc1ccc(F)cc1
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0.530n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent




US Patent US9796672 (2017)


BindingDB Entry DOI: 10.7270/Q2X92DFN
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM349518
PNG
(US10207991, Ex. Cpd. No. 34)
Show SMILES COc1cc2CN(Cc2cc1OC)C(C)(C)CCc1ccc(F)cc1
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0.530n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent




US Patent US10207991 (2019)


BindingDB Entry DOI: 10.7270/Q2BV7JRG
More data for this
Ligand-Target Pair
Sigma-2 receptor


(Rattus norvegicus (Rat))
BDBM50374598
PNG
(CHEMBL272603 | US9604926, Compound CM-156 | US9724...)
Show SMILES S=c1sc2ccccc2n1CCCCN1CCN(CC1)C1CCCCC1
Show InChI InChI=1S/C21H31N3S2/c25-21-24(19-10-4-5-11-20(19)26-21)13-7-6-12-22-14-16-23(17-15-22)18-8-2-1-3-9-18/h4-5,10-11,18H,1-3,6-9,12-17H2
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0.550n/an/an/an/an/an/an/an/a



THE UNIVERSITY OF MISSISSIPPI; THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY

US Patent




US Patent US9724435 (2017)


BindingDB Entry DOI: 10.7270/Q2BZ6856
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Mus musculus (Mouse))
BDBM50374598
PNG
(CHEMBL272603 | US9604926, Compound CM-156 | US9724...)
Show SMILES S=c1sc2ccccc2n1CCCCN1CCN(CC1)C1CCCCC1
Show InChI InChI=1S/C21H31N3S2/c25-21-24(19-10-4-5-11-20(19)26-21)13-7-6-12-22-14-16-23(17-15-22)18-8-2-1-3-9-18/h4-5,10-11,18H,1-3,6-9,12-17H2
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0.550n/an/an/an/an/an/an/an/a



THE UNIVERSITY OF MISSISSIPPI

US Patent




US Patent US9604926 (2017)


BindingDB Entry DOI: 10.7270/Q27D2X6J
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Mus musculus (Mouse))
BDBM312185
PNG
(US9604926, Compound CM-308 | US9724435, Compound C...)
Show SMILES COc1cc2CCN(CCCCn3c4ccccc4sc3=S)Cc2cc1OC
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0.560n/an/an/an/an/an/an/an/a



THE UNIVERSITY OF MISSISSIPPI

US Patent




US Patent US9604926 (2017)


BindingDB Entry DOI: 10.7270/Q27D2X6J
More data for this
Ligand-Target Pair
Sigma-2 receptor


(Rattus norvegicus (Rat))
BDBM312185
PNG
(US9604926, Compound CM-308 | US9724435, Compound C...)
Show SMILES COc1cc2CCN(CCCCn3c4ccccc4sc3=S)Cc2cc1OC
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0.560n/an/an/an/an/an/an/an/a



THE UNIVERSITY OF MISSISSIPPI; THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY

US Patent




US Patent US9724435 (2017)


BindingDB Entry DOI: 10.7270/Q2BZ6856
More data for this
Ligand-Target Pair
Sigma-2 receptor


(Rattus norvegicus (Rat))
BDBM312203
PNG
(US9604926, Compound CM-401 | US9724435, Compound C...)
Show SMILES CC(=O)c1ccc2n(CCCCN3CCC(=CC3)c3ccc(F)cc3)c(=O)oc2c1 |c:15|
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0.660n/an/an/an/an/an/an/an/a



THE UNIVERSITY OF MISSISSIPPI; THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY

US Patent




US Patent US9724435 (2017)


BindingDB Entry DOI: 10.7270/Q2BZ6856
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Mus musculus (Mouse))
BDBM312203
PNG
(US9604926, Compound CM-401 | US9724435, Compound C...)
Show SMILES CC(=O)c1ccc2n(CCCCN3CCC(=CC3)c3ccc(F)cc3)c(=O)oc2c1 |c:15|
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0.660n/an/an/an/an/an/an/an/a



THE UNIVERSITY OF MISSISSIPPI

US Patent




US Patent US9604926 (2017)


BindingDB Entry DOI: 10.7270/Q27D2X6J
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM349505
PNG
(US10207991, Ex. Cpd. No. 20)
Show SMILES COc1cc2CN(Cc2cc1OC)[C@@H](C)CCc1ccc(Cl)c(Cl)c1 |r|
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0.670n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent




US Patent US9796672 (2017)


BindingDB Entry DOI: 10.7270/Q2X92DFN
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM349505
PNG
(US10207991, Ex. Cpd. No. 20)
Show SMILES COc1cc2CN(Cc2cc1OC)[C@@H](C)CCc1ccc(Cl)c(Cl)c1 |r|
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0.670n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent




US Patent US10207991 (2019)


BindingDB Entry DOI: 10.7270/Q2BV7JRG
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Mus musculus (Mouse))
BDBM312166
PNG
(US9604926, Compound CM-170 | US9724435, Compound C...)
Show SMILES Fc1ccc(cc1)N1CCN(CCCCn2c3ccccc3oc2=O)CC1
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0.700n/an/an/an/an/an/an/an/a



THE UNIVERSITY OF MISSISSIPPI

US Patent




US Patent US9604926 (2017)


BindingDB Entry DOI: 10.7270/Q27D2X6J
More data for this
Ligand-Target Pair
Sigma-2 receptor


(Rattus norvegicus (Rat))
BDBM312166
PNG
(US9604926, Compound CM-170 | US9724435, Compound C...)
Show SMILES Fc1ccc(cc1)N1CCN(CCCCn2c3ccccc3oc2=O)CC1
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0.700n/an/an/an/an/an/an/an/a



THE UNIVERSITY OF MISSISSIPPI; THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY

US Patent




US Patent US9724435 (2017)


BindingDB Entry DOI: 10.7270/Q2BZ6856
More data for this
Ligand-Target Pair
Sigma-2 receptor


(Rattus norvegicus (Rat))
BDBM50374595
PNG
(CHEMBL272854 | US9604926, Compound CM-372 | US9724...)
Show SMILES S=c1oc2ccccc2n1CCCCN1CCN(CC1)C1CCCCC1
Show InChI InChI=1S/C21H31N3OS/c26-21-24(19-10-4-5-11-20(19)25-21)13-7-6-12-22-14-16-23(17-15-22)18-8-2-1-3-9-18/h4-5,10-11,18H,1-3,6-9,12-17H2
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0.770n/an/an/an/an/an/an/an/a



THE UNIVERSITY OF MISSISSIPPI; THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY

US Patent




US Patent US9724435 (2017)


BindingDB Entry DOI: 10.7270/Q2BZ6856
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Mus musculus (Mouse))
BDBM50374595
PNG
(CHEMBL272854 | US9604926, Compound CM-372 | US9724...)
Show SMILES S=c1oc2ccccc2n1CCCCN1CCN(CC1)C1CCCCC1
Show InChI InChI=1S/C21H31N3OS/c26-21-24(19-10-4-5-11-20(19)25-21)13-7-6-12-22-14-16-23(17-15-22)18-8-2-1-3-9-18/h4-5,10-11,18H,1-3,6-9,12-17H2
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0.770n/an/an/an/an/an/an/an/a



THE UNIVERSITY OF MISSISSIPPI

US Patent




US Patent US9604926 (2017)


BindingDB Entry DOI: 10.7270/Q27D2X6J
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Mus musculus (Mouse))
BDBM312231
PNG
(US9604926, Compound AZ-59 | US9724435, Compound AZ...)
Show SMILES CC(CCCn1c2ccccc2sc1=S)N1CCN(CC1)C1CCCCC1
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0.990n/an/an/an/an/an/an/an/a



THE UNIVERSITY OF MISSISSIPPI

US Patent




US Patent US9604926 (2017)


BindingDB Entry DOI: 10.7270/Q27D2X6J
More data for this
Ligand-Target Pair
Sigma-2 receptor


(Rattus norvegicus (Rat))
BDBM312231
PNG
(US9604926, Compound AZ-59 | US9724435, Compound AZ...)
Show SMILES CC(CCCn1c2ccccc2sc1=S)N1CCN(CC1)C1CCCCC1
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0.990n/an/an/an/an/an/an/an/a



THE UNIVERSITY OF MISSISSIPPI; THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY

US Patent




US Patent US9724435 (2017)


BindingDB Entry DOI: 10.7270/Q2BZ6856
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Mus musculus (Mouse))
BDBM50353846
PNG
(CHEMBL1831156 | US9604926, Compound CM-338 | US972...)
Show SMILES Fc1ccc(cc1)N1CCN(CCCCn2ccc3ccccc23)CC1
Show InChI InChI=1S/C22H26FN3/c23-20-7-9-21(10-8-20)25-17-15-24(16-18-25)12-3-4-13-26-14-11-19-5-1-2-6-22(19)26/h1-2,5-11,14H,3-4,12-13,15-18H2
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1.09n/an/an/an/an/an/an/an/a



THE UNIVERSITY OF MISSISSIPPI

US Patent




US Patent US9604926 (2017)


BindingDB Entry DOI: 10.7270/Q27D2X6J
More data for this
Ligand-Target Pair
Sigma-2 receptor


(Rattus norvegicus (Rat))
BDBM50353846
PNG
(CHEMBL1831156 | US9604926, Compound CM-338 | US972...)
Show SMILES Fc1ccc(cc1)N1CCN(CCCCn2ccc3ccccc23)CC1
Show InChI InChI=1S/C22H26FN3/c23-20-7-9-21(10-8-20)25-17-15-24(16-18-25)12-3-4-13-26-14-11-19-5-1-2-6-22(19)26/h1-2,5-11,14H,3-4,12-13,15-18H2
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1.09n/an/an/an/an/an/an/an/a



THE UNIVERSITY OF MISSISSIPPI; THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY

US Patent




US Patent US9724435 (2017)


BindingDB Entry DOI: 10.7270/Q2BZ6856
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM349569
PNG
(US10207991, Ex. Cpd. No. 87)
Show SMILES CC(C)COc1cc(CCC(C)(C)N2Cc3ccc(cc3C2)S(C)(=O)=O)ccc1O
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1.10n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent




US Patent US10207991 (2019)


BindingDB Entry DOI: 10.7270/Q2BV7JRG
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM349569
PNG
(US10207991, Ex. Cpd. No. 87)
Show SMILES CC(C)COc1cc(CCC(C)(C)N2Cc3ccc(cc3C2)S(C)(=O)=O)ccc1O
UniProtKB/SwissProt

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1.10n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent




US Patent US9796672 (2017)


BindingDB Entry DOI: 10.7270/Q2X92DFN
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Mus musculus (Mouse))
BDBM312194
PNG
(US9604926, Compound CM-356)
Show SMILES CC(=O)c1ccc2[nH]c(=O)n(CCCCN3CCN(CC3)c3ccc(F)cc3)c2c1
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1.21n/an/an/an/an/an/an/an/a



THE UNIVERSITY OF MISSISSIPPI

US Patent




US Patent US9604926 (2017)


BindingDB Entry DOI: 10.7270/Q27D2X6J
More data for this
Ligand-Target Pair
Sigma-2 receptor


(Rattus norvegicus (Rat))
BDBM330344
PNG
(US9724435, Compound CM-356)
Show SMILES CC(=O)c1ccc2oc(=O)n(CCCCN3CCN(CC3)c3ccc(F)cc3)c2c1
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1.21n/an/an/an/an/an/an/an/a



THE UNIVERSITY OF MISSISSIPPI; THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY

US Patent




US Patent US9724435 (2017)


BindingDB Entry DOI: 10.7270/Q2BZ6856
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM349570
PNG
(US10207991, Ex. Cpd. No. 88)
Show SMILES CC(C)COc1cc(CCC(C)(C)N2Cc3cccc(F)c3C2)ccc1O
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1.30n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent




US Patent US10207991 (2019)


BindingDB Entry DOI: 10.7270/Q2BV7JRG
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM349570
PNG
(US10207991, Ex. Cpd. No. 88)
Show SMILES CC(C)COc1cc(CCC(C)(C)N2Cc3cccc(F)c3C2)ccc1O
UniProtKB/SwissProt

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1.30n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent




US Patent US9796672 (2017)


BindingDB Entry DOI: 10.7270/Q2X92DFN
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM349578
PNG
(US10207991, Ex. Cpd. No. 103)
Show SMILES COc1cccc(CCC(C)(C)N2Cc3ccc(cc3C2)S(C)(=O)=O)c1
UniProtKB/SwissProt

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1.40n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent




US Patent US9796672 (2017)


BindingDB Entry DOI: 10.7270/Q2X92DFN
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM349578
PNG
(US10207991, Ex. Cpd. No. 103)
Show SMILES COc1cccc(CCC(C)(C)N2Cc3ccc(cc3C2)S(C)(=O)=O)c1
UniProtKB/SwissProt

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1.40n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent




US Patent US10207991 (2019)


BindingDB Entry DOI: 10.7270/Q2BV7JRG
More data for this
Ligand-Target Pair
Sigma-2 receptor


(Rattus norvegicus (Rat))
BDBM50374602
PNG
(CHEMBL272608 | US9604926, Compound SN-102 | US9724...)
Show SMILES O=c1sc2ccccc2n1CCCCCCN1CCN(CC1)C1CCCCC1
Show InChI InChI=1S/C23H35N3OS/c27-23-26(21-12-6-7-13-22(21)28-23)15-9-2-1-8-14-24-16-18-25(19-17-24)20-10-4-3-5-11-20/h6-7,12-13,20H,1-5,8-11,14-19H2
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1.49n/an/an/an/an/an/an/an/a



THE UNIVERSITY OF MISSISSIPPI; THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY

US Patent




US Patent US9724435 (2017)


BindingDB Entry DOI: 10.7270/Q2BZ6856
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Mus musculus (Mouse))
BDBM50374602
PNG
(CHEMBL272608 | US9604926, Compound SN-102 | US9724...)
Show SMILES O=c1sc2ccccc2n1CCCCCCN1CCN(CC1)C1CCCCC1
Show InChI InChI=1S/C23H35N3OS/c27-23-26(21-12-6-7-13-22(21)28-23)15-9-2-1-8-14-24-16-18-25(19-17-24)20-10-4-3-5-11-20/h6-7,12-13,20H,1-5,8-11,14-19H2
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1.49n/an/an/an/an/an/an/an/a



THE UNIVERSITY OF MISSISSIPPI

US Patent




US Patent US9604926 (2017)


BindingDB Entry DOI: 10.7270/Q27D2X6J
More data for this
Ligand-Target Pair
Sigma-2 receptor


(Rattus norvegicus (Rat))
BDBM50374602
PNG
(CHEMBL272608 | US9604926, Compound SN-102 | US9724...)
Show SMILES O=c1sc2ccccc2n1CCCCCCN1CCN(CC1)C1CCCCC1
Show InChI InChI=1S/C23H35N3OS/c27-23-26(21-12-6-7-13-22(21)28-23)15-9-2-1-8-14-24-16-18-25(19-17-24)20-10-4-3-5-11-20/h6-7,12-13,20H,1-5,8-11,14-19H2
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1.49n/an/an/an/an/an/an/an/a



THE UNIVERSITY OF MISSISSIPPI; THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY

US Patent




US Patent US9724435 (2017)


BindingDB Entry DOI: 10.7270/Q2BZ6856
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Mus musculus (Mouse))
BDBM50374602
PNG
(CHEMBL272608 | US9604926, Compound SN-102 | US9724...)
Show SMILES O=c1sc2ccccc2n1CCCCCCN1CCN(CC1)C1CCCCC1
Show InChI InChI=1S/C23H35N3OS/c27-23-26(21-12-6-7-13-22(21)28-23)15-9-2-1-8-14-24-16-18-25(19-17-24)20-10-4-3-5-11-20/h6-7,12-13,20H,1-5,8-11,14-19H2
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1.49n/an/an/an/an/an/an/an/a



THE UNIVERSITY OF MISSISSIPPI

US Patent




US Patent US9604926 (2017)


BindingDB Entry DOI: 10.7270/Q27D2X6J
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM349387
PNG
(US10207991, Ex. Cpd. No. 18)
Show SMILES C[C@H](CCc1ccc(Cl)c(Cl)c1)N1Cc2cc3ccccc3cc2C1 |r|
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1.5n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent




US Patent US10207991 (2019)


BindingDB Entry DOI: 10.7270/Q2BV7JRG
More data for this
Ligand-Target Pair
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