Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Testosterone 17-beta-dehydrogenase 3 (Rattus norvegicus) | BDBM50350421![]() (CHEMBL1813731) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
CHU de Qu£bec-Research Center (CHUL) Curated by ChEMBL | Assay Description Inhibition of 17beta-HSD3 in rat testes microsomes using [14C]-4-androstene-3,17-dione as substrate after 2 hrs | Bioorg Med Chem 23: 5433-51 (2015) BindingDB Entry DOI: 10.7270/Q20C4XHT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Testosterone 17-beta-dehydrogenase 3 (Rattus norvegicus) | BDBM50443289![]() (CHEMBL3088217) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Laval University Curated by ChEMBL | Assay Description Inhibition of 17beta-HSD3 in rat testes microsomal fraction using [14C]-4-androstene-3,17-dione as substrate assessed as testosterone formation after... | Bioorg Med Chem Lett 23: 6360-2 (2013) Article DOI: 10.1016/j.bmcl.2013.09.072 BindingDB Entry DOI: 10.7270/Q2KP83M4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Testosterone 17-beta-dehydrogenase 3 (Rattus norvegicus) | BDBM50443291![]() (CHEMBL3088087) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Laval University Curated by ChEMBL | Assay Description Inhibition of 17beta-HSD3 in rat testes microsomal fraction using [14C]-4-androstene-3,17-dione as substrate assessed as testosterone formation after... | Bioorg Med Chem Lett 23: 6360-2 (2013) Article DOI: 10.1016/j.bmcl.2013.09.072 BindingDB Entry DOI: 10.7270/Q2KP83M4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Testosterone 17-beta-dehydrogenase 3 (Rattus norvegicus) | BDBM50111763![]() (CHEMBL3605211) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
CHU de Qu£bec-Research Center (CHUL) Curated by ChEMBL | Assay Description Inhibition of 17beta-HSD3 in rat testes microsomes using [14C]-4-androstene-3,17-dione as substrate after 2 hrs | Bioorg Med Chem 23: 5433-51 (2015) BindingDB Entry DOI: 10.7270/Q20C4XHT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Testosterone 17-beta-dehydrogenase 3 (Mus musculus) | BDBM50360767![]() (CHEMBL1934493) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Chemical Co., Ltd Curated by ChEMBL | Assay Description Inhibition of 17beta-HSD3 in mouse testes homogenate | Bioorg Med Chem Lett 22: 504-7 (2011) Article DOI: 10.1016/j.bmcl.2011.10.095 BindingDB Entry DOI: 10.7270/Q2BG2PFD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Testosterone 17-beta-dehydrogenase 3 (Rattus norvegicus) | BDBM50443290![]() (CHEMBL3088089) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 58 | n/a | n/a | n/a | n/a | n/a | n/a |
Laval University Curated by ChEMBL | Assay Description Inhibition of 17beta-HSD3 in rat testes microsomal fraction using [14C]-4-androstene-3,17-dione as substrate assessed as testosterone formation after... | Bioorg Med Chem Lett 23: 6360-2 (2013) Article DOI: 10.1016/j.bmcl.2013.09.072 BindingDB Entry DOI: 10.7270/Q2KP83M4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Testosterone 17-beta-dehydrogenase 3 (Rattus norvegicus) | BDBM50315879![]() (1,5-bis(4-ethoxyphenyl)penta-1,4-dien-3-one | CHEM...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
School of Pharmacy Curated by ChEMBL | Assay Description Inhibition of 17beta-HSD3 in Sprague-Dawley rat laydig cells | Bioorg Med Chem Lett 20: 2549-51 (2010) Article DOI: 10.1016/j.bmcl.2010.02.089 BindingDB Entry DOI: 10.7270/Q2R211J3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Testosterone 17-beta-dehydrogenase 3 (Rattus norvegicus) | BDBM50111764![]() (CHEMBL3605212) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 88 | n/a | n/a | n/a | n/a | n/a | n/a |
CHU de Qu£bec-Research Center (CHUL) Curated by ChEMBL | Assay Description Inhibition of 17beta-HSD3 in rat testes microsomes using [14C]-4-androstene-3,17-dione as substrate after 2 hrs | Bioorg Med Chem 23: 5433-51 (2015) BindingDB Entry DOI: 10.7270/Q20C4XHT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Testosterone 17-beta-dehydrogenase 3 (Rattus norvegicus) | BDBM17639![]() ((1S,2S,5R,7S,10R,11S,15S)-5-hydroxy-2,15-dimethylt...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem | PubMed | n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
CHU de Qu£bec-Research Center (CHUL) Curated by ChEMBL | Assay Description Inhibition of 17beta-HSD3 in rat testes microsomes using [14C]-4-androstene-3,17-dione as substrate after 2 hrs | Bioorg Med Chem 23: 5433-51 (2015) BindingDB Entry DOI: 10.7270/Q20C4XHT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Testosterone 17-beta-dehydrogenase 3 (Rattus norvegicus) | BDBM50266759![]() ((1E,4E)-1,5-bis(4-fluorophenyl)penta-1,4-dien-3-on...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
School of Pharmacy Curated by ChEMBL | Assay Description Inhibition of 17beta-HSD3 in Sprague-Dawley rat laydig cells | Bioorg Med Chem Lett 20: 2549-51 (2010) Article DOI: 10.1016/j.bmcl.2010.02.089 BindingDB Entry DOI: 10.7270/Q2R211J3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Testosterone 17-beta-dehydrogenase 3 (Rattus norvegicus) | BDBM91713![]() (Androst-4-en-3,17-dione, 2 | Androst-4-ene-3,17-di...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents | PubMed | n/a | n/a | 169 | n/a | n/a | n/a | n/a | n/a | n/a |
CHU de Qu£bec-Research Center (CHUL) Curated by ChEMBL | Assay Description Inhibition of 17beta-HSD3 in rat testes microsomes using [14C]-4-androstene-3,17-dione as substrate after 2 hrs | Bioorg Med Chem 23: 5433-51 (2015) BindingDB Entry DOI: 10.7270/Q20C4XHT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Testosterone 17-beta-dehydrogenase 3 (Rattus norvegicus) | BDBM50315878![]() (2,5-bis(3-bromobenzylidene)cyclopentanone | CHEMBL...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
School of Pharmacy Curated by ChEMBL | Assay Description Inhibition of 17beta-HSD3 in Sprague-Dawley rat testis microsomes | Bioorg Med Chem Lett 20: 2549-51 (2010) Article DOI: 10.1016/j.bmcl.2010.02.089 BindingDB Entry DOI: 10.7270/Q2R211J3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Testosterone 17-beta-dehydrogenase 3 (Rattus norvegicus) | BDBM50315880![]() (1,5-bis(4-(tetrahydro-2H-pyran-3-yloxy)phenyl)pent...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
School of Pharmacy Curated by ChEMBL | Assay Description Inhibition of 17beta-HSD3 in Sprague-Dawley rat laydig cells | Bioorg Med Chem Lett 20: 2549-51 (2010) Article DOI: 10.1016/j.bmcl.2010.02.089 BindingDB Entry DOI: 10.7270/Q2R211J3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Testosterone 17-beta-dehydrogenase 3 (Rattus norvegicus) | BDBM50241208![]() ((2E,6E)-2,6-bis(3,4,5-trimethoxybenzylidene)cycloh...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
School of Pharmacy Curated by ChEMBL | Assay Description Inhibition of 17beta-HSD3 in Sprague-Dawley rat testis microsomes | Bioorg Med Chem Lett 20: 2549-51 (2010) Article DOI: 10.1016/j.bmcl.2010.02.089 BindingDB Entry DOI: 10.7270/Q2R211J3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Testosterone 17-beta-dehydrogenase 3 (Rattus norvegicus) | BDBM50067040![]() (((E,E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-hept...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
School of Pharmacy Curated by ChEMBL | Assay Description Inhibition of 17beta-HSD3 in Sprague-Dawley rat testis microsomes | Bioorg Med Chem Lett 20: 2549-51 (2010) Article DOI: 10.1016/j.bmcl.2010.02.089 BindingDB Entry DOI: 10.7270/Q2R211J3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Testosterone 17-beta-dehydrogenase 3 (Rattus norvegicus) | BDBM50266759![]() ((1E,4E)-1,5-bis(4-fluorophenyl)penta-1,4-dien-3-on...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
School of Pharmacy Curated by ChEMBL | Assay Description Inhibition of 17beta-HSD3 in Sprague-Dawley rat testis microsomes | Bioorg Med Chem Lett 20: 2549-51 (2010) Article DOI: 10.1016/j.bmcl.2010.02.089 BindingDB Entry DOI: 10.7270/Q2R211J3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Testosterone 17-beta-dehydrogenase 3 (Rattus norvegicus) | BDBM50315881![]() (1,5-bis(3-bromophenyl)penta-1,4-dien-3-one | CHEMB...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
School of Pharmacy Curated by ChEMBL | Assay Description Inhibition of 17beta-HSD3 in Sprague-Dawley rat testis microsomes | Bioorg Med Chem Lett 20: 2549-51 (2010) Article DOI: 10.1016/j.bmcl.2010.02.089 BindingDB Entry DOI: 10.7270/Q2R211J3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Testosterone 17-beta-dehydrogenase 3 (Rattus norvegicus) | BDBM50067040![]() (((E,E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-hept...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 9.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
School of Pharmacy Curated by ChEMBL | Assay Description Inhibition of 17beta-HSD3 in Sprague-Dawley rat laydig cells | Bioorg Med Chem Lett 20: 2549-51 (2010) Article DOI: 10.1016/j.bmcl.2010.02.089 BindingDB Entry DOI: 10.7270/Q2R211J3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Testosterone 17-beta-dehydrogenase 3 (Rattus norvegicus) | BDBM50241208![]() ((2E,6E)-2,6-bis(3,4,5-trimethoxybenzylidene)cycloh...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
School of Pharmacy Curated by ChEMBL | Assay Description Inhibition of 17beta-HSD3 in Sprague-Dawley rat laydig cells | Bioorg Med Chem Lett 20: 2549-51 (2010) Article DOI: 10.1016/j.bmcl.2010.02.089 BindingDB Entry DOI: 10.7270/Q2R211J3 | |||||||||||
More data for this Ligand-Target Pair |