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Compile Data Set for Download or QSAR

Found 115 hits Enz. Inhib. hit(s) with Target = 'Transcriptional activator protein luxR'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transcriptional activator protein luxR


(Vibrio fischeri)
BDBM50350709
PNG
(CHEMBL1812080)
Show SMILES CCCCCCCC(=O)N[C@H]1CCSC1=O |r|
Show InChI InChI=1S/C12H21NO2S/c1-2-3-4-5-6-7-11(14)13-10-8-9-16-12(10)15/h10H,2-9H2,1H3,(H,13,14)/t10-/m0/s1
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University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri ESI 114 (delta-LuxI) LuxR assessed as inhibition of OdDHL-induced quorum sensing activation after 8 hrs by bet...


Bioorg Med Chem 19: 4820-8 (2011)


Article DOI: 10.1016/j.bmc.2011.06.071
BindingDB Entry DOI: 10.7270/Q27D2W47
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri)
BDBM50350708
PNG
(CHEMBL1814832)
Show SMILES CCCCCCC(=O)N[C@H]1CCSC1=O |r|
Show InChI InChI=1S/C11H19NO2S/c1-2-3-4-5-6-10(13)12-9-7-8-15-11(9)14/h9H,2-8H2,1H3,(H,12,13)/t9-/m0/s1
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University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri ESI 114 (delta-LuxI) LuxR assessed as inhibition of OdDHL-induced quorum sensing activation after 8 hrs by bet...


Bioorg Med Chem 19: 4820-8 (2011)


Article DOI: 10.1016/j.bmc.2011.06.071
BindingDB Entry DOI: 10.7270/Q27D2W47
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri)
BDBM50350704
PNG
(CHEMBL1814829)
Show SMILES CCCCCC(=O)CC(=O)N[C@H]1CCSC1=O |r|
Show InChI InChI=1S/C12H19NO3S/c1-2-3-4-5-9(14)8-11(15)13-10-6-7-17-12(10)16/h10H,2-8H2,1H3,(H,13,15)/t10-/m0/s1
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n/an/a 350n/an/an/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri ESI 114 (delta-LuxI) LuxR assessed as inhibition of OdDHL-induced quorum sensing activation after 8 hrs by bet...


Bioorg Med Chem 19: 4820-8 (2011)


Article DOI: 10.1016/j.bmc.2011.06.071
BindingDB Entry DOI: 10.7270/Q27D2W47
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri)
BDBM50350711
PNG
(CHEMBL1812089)
Show SMILES O=C(Cc1ccc(cc1)-c1ccccc1)N[C@H]1CCSC1=O |r|
Show InChI InChI=1S/C18H17NO2S/c20-17(19-16-10-11-22-18(16)21)12-13-6-8-15(9-7-13)14-4-2-1-3-5-14/h1-9,16H,10-12H2,(H,19,20)/t16-/m0/s1
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n/an/a 350n/an/an/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri ESI 114 (delta-LuxI) LuxR assessed as inhibition of OdDHL-induced quorum sensing activation after 8 hrs by bet...


Bioorg Med Chem 19: 4820-8 (2011)


Article DOI: 10.1016/j.bmc.2011.06.071
BindingDB Entry DOI: 10.7270/Q27D2W47
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri (strain ATCC 700601 / ES114))
BDBM50265812
PNG
((S)-3-(3-iodophenyl)-N-(2-oxotetrahydrofuran-3-yl)...)
Show SMILES Ic1cccc(CCC(=O)N[C@H]2CCOC2=O)c1 |r|
Show InChI InChI=1S/C13H14INO3/c14-10-3-1-2-9(8-10)4-5-12(16)15-11-6-7-18-13(11)17/h1-3,8,11H,4-7H2,(H,15,16)/t11-/m0/s1
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University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay


Bioorg Med Chem Lett 18: 5978-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.089
BindingDB Entry DOI: 10.7270/Q2Q81CXX
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri)
BDBM50351509
PNG
(CHEMBL8799)
Show SMILES CCCCCCCCCC(=O)N[C@H]1CCOC1=O
Show InChI InChI=1S/C14H25NO3/c1-2-3-4-5-6-7-8-9-13(16)15-12-10-11-18-14(12)17/h12H,2-11H2,1H3,(H,15,16)/t12-/m0/s1
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The Scripps Research Institute

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri luxR receptor in presence of 5 uM 3-oxo-C6-HSL


J Med Chem 53: 7467-89 (2010)


Article DOI: 10.1021/jm901742e
BindingDB Entry DOI: 10.7270/Q2S75GPT
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri)
BDBM50350703
PNG
(CHEMBL1814828)
Show SMILES CCCCCCCCCC(=O)CC(=O)N[C@H]1CCSC1=O |r|
Show InChI InChI=1S/C16H27NO3S/c1-2-3-4-5-6-7-8-9-13(18)12-15(19)17-14-10-11-21-16(14)20/h14H,2-12H2,1H3,(H,17,19)/t14-/m0/s1
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University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri ESI 114 (delta-LuxI) LuxR assessed as inhibition of OdDHL-induced quorum sensing activation after 8 hrs by bet...


Bioorg Med Chem 19: 4820-8 (2011)


Article DOI: 10.1016/j.bmc.2011.06.071
BindingDB Entry DOI: 10.7270/Q27D2W47
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri (strain ATCC 700601 / ES114))
BDBM50265861
PNG
((S)-N-(2-oxotetrahydrofuran-3-yl)-3-(3-(trifluorom...)
Show SMILES FC(F)(F)c1cccc(CCC(=O)N[C@H]2CCOC2=O)c1 |r|
Show InChI InChI=1S/C14H14F3NO3/c15-14(16,17)10-3-1-2-9(8-10)4-5-12(19)18-11-6-7-21-13(11)20/h1-3,8,11H,4-7H2,(H,18,19)/t11-/m0/s1
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University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay


Bioorg Med Chem Lett 18: 5978-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.089
BindingDB Entry DOI: 10.7270/Q2Q81CXX
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri (strain ATCC 700601 / ES114))
BDBM50265810
PNG
((S)-3-(3-bromophenyl)-N-(2-oxotetrahydrofuran-3-yl...)
Show SMILES Brc1cccc(CCC(=O)N[C@H]2CCOC2=O)c1 |r|
Show InChI InChI=1S/C13H14BrNO3/c14-10-3-1-2-9(8-10)4-5-12(16)15-11-6-7-18-13(11)17/h1-3,8,11H,4-7H2,(H,15,16)/t11-/m0/s1
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University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay


Bioorg Med Chem Lett 18: 5978-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.089
BindingDB Entry DOI: 10.7270/Q2Q81CXX
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri)
BDBM50266165
PNG
((S)-N-(2-oxotetrahydrofuran-3-yl)-2-(4-(trifluorom...)
Show SMILES FC(F)(F)c1ccc(CC(=O)N[C@H]2CCOC2=O)cc1 |r|
Show InChI InChI=1S/C13H12F3NO3/c14-13(15,16)9-3-1-8(2-4-9)7-11(18)17-10-5-6-20-12(10)19/h1-4,10H,5-7H2,(H,17,18)/t10-/m0/s1
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n/an/a 610n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri luxR receptor in presence of 5 uM 3-oxo-C6-HSL


J Med Chem 53: 7467-89 (2010)


Article DOI: 10.1021/jm901742e
BindingDB Entry DOI: 10.7270/Q2S75GPT
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri (strain ATCC 700601 / ES114))
BDBM50266165
PNG
((S)-N-(2-oxotetrahydrofuran-3-yl)-2-(4-(trifluorom...)
Show SMILES FC(F)(F)c1ccc(CC(=O)N[C@H]2CCOC2=O)cc1 |r|
Show InChI InChI=1S/C13H12F3NO3/c14-13(15,16)9-3-1-8(2-4-9)7-11(18)17-10-5-6-20-12(10)19/h1-4,10H,5-7H2,(H,17,18)/t10-/m0/s1
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n/an/a 610n/an/an/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay


Bioorg Med Chem Lett 18: 5978-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.089
BindingDB Entry DOI: 10.7270/Q2Q81CXX
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri (strain ATCC 700601 / ES114))
BDBM50265811
PNG
((S)-3-(4-iodophenyl)-N-(2-oxotetrahydrofuran-3-yl)...)
Show SMILES Ic1ccc(CCC(=O)N[C@H]2CCOC2=O)cc1 |r|
Show InChI InChI=1S/C13H14INO3/c14-10-4-1-9(2-5-10)3-6-12(16)15-11-7-8-18-13(11)17/h1-2,4-5,11H,3,6-8H2,(H,15,16)/t11-/m0/s1
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University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay


Bioorg Med Chem Lett 18: 5978-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.089
BindingDB Entry DOI: 10.7270/Q2Q81CXX
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri)
BDBM50350710
PNG
(CHEMBL1812087)
Show SMILES Brc1ccc(CC(=O)N[C@H]2CCSC2=O)cc1 |r|
Show InChI InChI=1S/C12H12BrNO2S/c13-9-3-1-8(2-4-9)7-11(15)14-10-5-6-17-12(10)16/h1-4,10H,5-7H2,(H,14,15)/t10-/m0/s1
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n/an/a 770n/an/an/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri ESI 114 (delta-LuxI) LuxR assessed as inhibition of OdDHL-induced quorum sensing activation after 8 hrs by bet...


Bioorg Med Chem 19: 4820-8 (2011)


Article DOI: 10.1016/j.bmc.2011.06.071
BindingDB Entry DOI: 10.7270/Q27D2W47
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri)
BDBM50351508
PNG
(CHEMBL259352)
Show SMILES CCCCCCCC(=O)N[C@H]1CCOC1=O |r|
Show InChI InChI=1S/C12H21NO3/c1-2-3-4-5-6-7-11(14)13-10-8-9-16-12(10)15/h10H,2-9H2,1H3,(H,13,14)/t10-/m0/s1
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The Scripps Research Institute

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri luxR receptor in presence of 5 uM 3-oxo-C6-HSL


J Med Chem 53: 7467-89 (2010)


Article DOI: 10.1021/jm901742e
BindingDB Entry DOI: 10.7270/Q2S75GPT
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri)
BDBM50350707
PNG
(CHEMBL1814831)
Show SMILES CCCCCC(=O)N[C@H]1CCSC1=O |r|
Show InChI InChI=1S/C10H17NO2S/c1-2-3-4-5-9(12)11-8-6-7-14-10(8)13/h8H,2-7H2,1H3,(H,11,12)/t8-/m0/s1
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University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri ESI 114 (delta-LuxI) LuxR assessed as inhibition of OdDHL-induced quorum sensing activation after 8 hrs by bet...


Bioorg Med Chem 19: 4820-8 (2011)


Article DOI: 10.1016/j.bmc.2011.06.071
BindingDB Entry DOI: 10.7270/Q27D2W47
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri)
BDBM50266163
PNG
((S)-2-(4-iodophenyl)-N-(2-oxotetrahydrofuran-3-yl)...)
Show SMILES Ic1ccc(CC(=O)N[C@H]2CCOC2=O)cc1 |r|
Show InChI InChI=1S/C12H12INO3/c13-9-3-1-8(2-4-9)7-11(15)14-10-5-6-17-12(10)16/h1-4,10H,5-7H2,(H,14,15)/t10-/m0/s1
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The Scripps Research Institute

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri luxR receptor in presence of 5 uM 3-oxo-C6-HSL


J Med Chem 53: 7467-89 (2010)


Article DOI: 10.1021/jm901742e
BindingDB Entry DOI: 10.7270/Q2S75GPT
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri (strain ATCC 700601 / ES114))
BDBM50266163
PNG
((S)-2-(4-iodophenyl)-N-(2-oxotetrahydrofuran-3-yl)...)
Show SMILES Ic1ccc(CC(=O)N[C@H]2CCOC2=O)cc1 |r|
Show InChI InChI=1S/C12H12INO3/c13-9-3-1-8(2-4-9)7-11(15)14-10-5-6-17-12(10)16/h1-4,10H,5-7H2,(H,14,15)/t10-/m0/s1
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University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay


Bioorg Med Chem Lett 18: 5978-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.089
BindingDB Entry DOI: 10.7270/Q2Q81CXX
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri (strain ATCC 700601 / ES114))
BDBM50265901
PNG
((S)-3-(3-nitrophenyl)-N-(2-oxotetrahydrofuran-3-yl...)
Show SMILES [O-][N+](=O)c1cccc(CCC(=O)N[C@H]2CCOC2=O)c1 |r|
Show InChI InChI=1S/C13H14N2O5/c16-12(14-11-6-7-20-13(11)17)5-4-9-2-1-3-10(8-9)15(18)19/h1-3,8,11H,4-7H2,(H,14,16)/t11-/m0/s1
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University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay


Bioorg Med Chem Lett 18: 5978-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.089
BindingDB Entry DOI: 10.7270/Q2Q81CXX
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri (strain ATCC 700601 / ES114))
BDBM50266238
PNG
((S)-2-(naphthalen-2-yl)-N-(2-oxotetrahydrofuran-3-...)
Show SMILES O=C(Cc1ccc2ccccc2c1)N[C@H]1CCOC1=O |r|
Show InChI InChI=1S/C16H15NO3/c18-15(17-14-7-8-20-16(14)19)10-11-5-6-12-3-1-2-4-13(12)9-11/h1-6,9,14H,7-8,10H2,(H,17,18)/t14-/m0/s1
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University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay


Bioorg Med Chem Lett 18: 5978-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.089
BindingDB Entry DOI: 10.7270/Q2Q81CXX
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri (strain ATCC 700601 / ES114))
BDBM50266164
PNG
((S)-2-(4-nitrophenyl)-N-(2-oxotetrahydrofuran-3-yl...)
Show SMILES [O-][N+](=O)c1ccc(CC(=O)N[C@H]2CCOC2=O)cc1 |r|
Show InChI InChI=1S/C12H12N2O5/c15-11(13-10-5-6-19-12(10)16)7-8-1-3-9(4-2-8)14(17)18/h1-4,10H,5-7H2,(H,13,15)/t10-/m0/s1
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University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay


Bioorg Med Chem Lett 18: 5978-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.089
BindingDB Entry DOI: 10.7270/Q2Q81CXX
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri (strain ATCC 700601 / ES114))
BDBM50265809
PNG
((S)-3-(4-chlorophenyl)-N-(2-oxotetrahydrofuran-3-y...)
Show SMILES Clc1ccc(CCC(=O)N[C@H]2CCOC2=O)cc1 |r|
Show InChI InChI=1S/C13H14ClNO3/c14-10-4-1-9(2-5-10)3-6-12(16)15-11-7-8-18-13(11)17/h1-2,4-5,11H,3,6-8H2,(H,15,16)/t11-/m0/s1
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University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay


Bioorg Med Chem Lett 18: 5978-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.089
BindingDB Entry DOI: 10.7270/Q2Q81CXX
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri (strain ATCC 700601 / ES114))
BDBM50265900
PNG
((S)-3-(4-nitrophenyl)-N-(2-oxotetrahydrofuran-3-yl...)
Show SMILES [O-][N+](=O)c1ccc(CCC(=O)N[C@H]2CCOC2=O)cc1 |r|
Show InChI InChI=1S/C13H14N2O5/c16-12(14-11-7-8-20-13(11)17)6-3-9-1-4-10(5-2-9)15(18)19/h1-2,4-5,11H,3,6-8H2,(H,14,16)/t11-/m0/s1
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n/an/a 990n/an/an/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay


Bioorg Med Chem Lett 18: 5978-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.089
BindingDB Entry DOI: 10.7270/Q2Q81CXX
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri (strain ATCC 700601 / ES114))
BDBM50266236
PNG
((S)-2-(4-fluoro-3-(trifluoromethyl)phenyl)-N-(2-ox...)
Show SMILES Fc1ccc(CC(=O)N[C@H]2CCOC2=O)cc1C(F)(F)F |r|
Show InChI InChI=1S/C13H11F4NO3/c14-9-2-1-7(5-8(9)13(15,16)17)6-11(19)18-10-3-4-21-12(10)20/h1-2,5,10H,3-4,6H2,(H,18,19)/t10-/m0/s1
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n/an/a 1.00E+3n/an/an/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay


Bioorg Med Chem Lett 18: 5978-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.089
BindingDB Entry DOI: 10.7270/Q2Q81CXX
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri (strain ATCC 700601 / ES114))
BDBM50266266
PNG
((S)-2-(naphthalen-1-yl)-N-(2-oxotetrahydrofuran-3-...)
Show SMILES O=C(Cc1cccc2ccccc12)N[C@H]1CCOC1=O |r|
Show InChI InChI=1S/C16H15NO3/c18-15(17-14-8-9-20-16(14)19)10-12-6-3-5-11-4-1-2-7-13(11)12/h1-7,14H,8-10H2,(H,17,18)/t14-/m0/s1
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n/an/a 1.30E+3n/an/an/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay


Bioorg Med Chem Lett 18: 5978-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.089
BindingDB Entry DOI: 10.7270/Q2Q81CXX
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri (strain ATCC 700601 / ES114))
BDBM50266234
PNG
((S)-N-(2-oxotetrahydrofuran-3-yl)-2-(4-(trifluorom...)
Show SMILES FC(F)(F)Sc1ccc(CC(=O)N[C@H]2CCOC2=O)cc1 |r|
Show InChI InChI=1S/C13H12F3NO3S/c14-13(15,16)21-9-3-1-8(2-4-9)7-11(18)17-10-5-6-20-12(10)19/h1-4,10H,5-7H2,(H,17,18)/t10-/m0/s1
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University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay


Bioorg Med Chem Lett 18: 5978-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.089
BindingDB Entry DOI: 10.7270/Q2Q81CXX
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri (strain ATCC 700601 / ES114))
BDBM50241433
PNG
((S)-3-(4-bromophenyl)-N-(2-oxo-tetrahydrofuran-3-y...)
Show SMILES Brc1ccc(CCC(=O)N[C@H]2CCOC2=O)cc1 |r|
Show InChI InChI=1S/C13H14BrNO3/c14-10-4-1-9(2-5-10)3-6-12(16)15-11-7-8-18-13(11)17/h1-2,4-5,11H,3,6-8H2,(H,15,16)/t11-/m0/s1
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n/an/a 1.35E+3n/an/an/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay


Bioorg Med Chem Lett 18: 5978-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.089
BindingDB Entry DOI: 10.7270/Q2Q81CXX
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri)
BDBM50241433
PNG
((S)-3-(4-bromophenyl)-N-(2-oxo-tetrahydrofuran-3-y...)
Show SMILES Brc1ccc(CCC(=O)N[C@H]2CCOC2=O)cc1 |r|
Show InChI InChI=1S/C13H14BrNO3/c14-10-4-1-9(2-5-10)3-6-12(16)15-11-7-8-18-13(11)17/h1-2,4-5,11H,3,6-8H2,(H,15,16)/t11-/m0/s1
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The Scripps Research Institute

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri luxR receptor in presence of 5 uM 3-oxo-C6-HSL


J Med Chem 53: 7467-89 (2010)


Article DOI: 10.1021/jm901742e
BindingDB Entry DOI: 10.7270/Q2S75GPT
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri)
BDBM50300132
PNG
(CHEMBL584972 | N-heptanoyl-L-homoserine lactone)
Show SMILES CCCCCCC(=O)N[C@H]1CCOC1=O |r|
Show InChI InChI=1S/C11H19NO3/c1-2-3-4-5-6-10(13)12-9-7-8-15-11(9)14/h9H,2-8H2,1H3,(H,12,13)/t9-/m0/s1
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n/an/a 1.36E+3n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri luxR receptor in presence of 5 uM 3-oxo-C6-HSL


J Med Chem 53: 7467-89 (2010)


Article DOI: 10.1021/jm901742e
BindingDB Entry DOI: 10.7270/Q2S75GPT
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri (strain ATCC 700601 / ES114))
BDBM50266201
PNG
((S)-N-(2-oxotetrahydrofuran-3-yl)-2-(3-(trifluorom...)
Show SMILES FC(F)(F)c1cccc(CC(=O)N[C@H]2CCOC2=O)c1 |r|
Show InChI InChI=1S/C13H12F3NO3/c14-13(15,16)9-3-1-2-8(6-9)7-11(18)17-10-4-5-20-12(10)19/h1-3,6,10H,4-5,7H2,(H,17,18)/t10-/m0/s1
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University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay


Bioorg Med Chem Lett 18: 5978-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.089
BindingDB Entry DOI: 10.7270/Q2Q81CXX
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri)
BDBM50350660
PNG
(CHEMBL1813552)
Show SMILES CCCCCCCCCCCCn1cc[n+](c1)C1c2ccccc2-c2ccccc12
Show InChI InChI=1S/C28H37N2/c1-2-3-4-5-6-7-8-9-10-15-20-29-21-22-30(23-29)28-26-18-13-11-16-24(26)25-17-12-14-19-27(25)28/h11-14,16-19,21-23,28H,2-10,15,20H2,1H3/q+1
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n/an/a 1.40E+3n/an/an/an/an/an/a



INSA Lyon

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri LuxR assessed as inhibition of 3-oxo-C6-HSL-induced quorum sensing activation mediated bioluminescence


Bioorg Med Chem 19: 4868-75 (2011)


Article DOI: 10.1016/j.bmc.2011.06.075
BindingDB Entry DOI: 10.7270/Q2CC112H
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri (strain ATCC 700601 / ES114))
BDBM50266233
PNG
((S)-2-(3-(methylthio)phenyl)-N-(2-oxotetrahydrofur...)
Show SMILES CSc1cccc(CC(=O)N[C@H]2CCOC2=O)c1 |r|
Show InChI InChI=1S/C13H15NO3S/c1-18-10-4-2-3-9(7-10)8-12(15)14-11-5-6-17-13(11)16/h2-4,7,11H,5-6,8H2,1H3,(H,14,15)/t11-/m0/s1
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n/an/a 1.50E+3n/an/an/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay


Bioorg Med Chem Lett 18: 5978-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.089
BindingDB Entry DOI: 10.7270/Q2Q81CXX
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri (strain ATCC 700601 / ES114))
BDBM50265813
PNG
((S)-3-(4-(methylthio)phenyl)-N-(2-oxotetrahydrofur...)
Show SMILES CSc1ccc(CCC(=O)N[C@H]2CCOC2=O)cc1 |r|
Show InChI InChI=1S/C14H17NO3S/c1-19-11-5-2-10(3-6-11)4-7-13(16)15-12-8-9-18-14(12)17/h2-3,5-6,12H,4,7-9H2,1H3,(H,15,16)/t12-/m0/s1
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University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay


Bioorg Med Chem Lett 18: 5978-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.089
BindingDB Entry DOI: 10.7270/Q2Q81CXX
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri (strain ATCC 700601 / ES114))
BDBM50266308
PNG
((S)-2-(4-iodophenoxy)-N-(2-oxotetrahydrofuran-3-yl...)
Show SMILES Ic1ccc(OCC(=O)N[C@H]2CCOC2=O)cc1 |r|
Show InChI InChI=1S/C12H12INO4/c13-8-1-3-9(4-2-8)18-7-11(15)14-10-5-6-17-12(10)16/h1-4,10H,5-7H2,(H,14,15)/t10-/m0/s1
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University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay


Bioorg Med Chem Lett 18: 5978-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.089
BindingDB Entry DOI: 10.7270/Q2Q81CXX
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri)
BDBM50373056
PNG
(CHEMBL261163)
Show SMILES CCCCCNS(=O)(=O)NC1CCOC1=O
Show InChI InChI=1S/C9H18N2O4S/c1-2-3-4-6-10-16(13,14)11-8-5-7-15-9(8)12/h8,10-11H,2-7H2,1H3
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n/an/a 2.00E+3n/an/an/an/an/an/a



INSA Lyon

Curated by ChEMBL


Assay Description
Antagonist activity at LuxR in Vibrio fischeri assessed as inhibition of N-3-oxos-hexanoyl-L-homoserine lactone induced luminescence


Bioorg Med Chem 16: 3550-6 (2008)


Article DOI: 10.1016/j.bmc.2008.02.023
BindingDB Entry DOI: 10.7270/Q2X63NTT
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri (strain ATCC 700601 / ES114))
BDBM50266199
PNG
((S)-N-(2-oxotetrahydrofuran-3-yl)-2-m-tolylacetami...)
Show SMILES Cc1cccc(CC(=O)N[C@H]2CCOC2=O)c1 |r|
Show InChI InChI=1S/C13H15NO3/c1-9-3-2-4-10(7-9)8-12(15)14-11-5-6-17-13(11)16/h2-4,7,11H,5-6,8H2,1H3,(H,14,15)/t11-/m0/s1
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n/an/a 2.00E+3n/an/an/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay


Bioorg Med Chem Lett 18: 5978-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.089
BindingDB Entry DOI: 10.7270/Q2Q81CXX
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri (strain ATCC 700601 / ES114))
BDBM50266313
PNG
((S)-N-(2-oxotetrahydrofuran-3-yl)-3-m-tolylpropana...)
Show SMILES Cc1cccc(CCC(=O)N[C@H]2CCOC2=O)c1 |r|
Show InChI InChI=1S/C14H17NO3/c1-10-3-2-4-11(9-10)5-6-13(16)15-12-7-8-18-14(12)17/h2-4,9,12H,5-8H2,1H3,(H,15,16)/t12-/m0/s1
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n/an/a 2.10E+3n/an/an/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay


Bioorg Med Chem Lett 18: 5978-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.089
BindingDB Entry DOI: 10.7270/Q2Q81CXX
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri (strain ATCC 700601 / ES114))
BDBM50266203
PNG
((S)-2-(4-(methylthio)phenyl)-N-(2-oxotetrahydrofur...)
Show SMILES CSc1ccc(CC(=O)N[C@H]2CCOC2=O)cc1 |r|
Show InChI InChI=1S/C13H15NO3S/c1-18-10-4-2-9(3-5-10)8-12(15)14-11-6-7-17-13(11)16/h2-5,11H,6-8H2,1H3,(H,14,15)/t11-/m0/s1
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n/an/a 2.10E+3n/an/an/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay


Bioorg Med Chem Lett 18: 5978-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.089
BindingDB Entry DOI: 10.7270/Q2Q81CXX
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri (strain ATCC 700601 / ES114))
BDBM50266312
PNG
((S)-N-(2-oxotetrahydrofuran-3-yl)-3-p-tolylpropana...)
Show SMILES Cc1ccc(CCC(=O)N[C@H]2CCOC2=O)cc1 |r|
Show InChI InChI=1S/C14H17NO3/c1-10-2-4-11(5-3-10)6-7-13(16)15-12-8-9-18-14(12)17/h2-5,12H,6-9H2,1H3,(H,15,16)/t12-/m0/s1
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n/an/a 2.20E+3n/an/an/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay


Bioorg Med Chem Lett 18: 5978-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.089
BindingDB Entry DOI: 10.7270/Q2Q81CXX
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri (strain ATCC 700601 / ES114))
BDBM50265814
PNG
((S)-N-(2-oxotetrahydrofuran-3-yl)-3-(4-(trifluorom...)
Show SMILES FC(F)(F)c1ccc(CCC(=O)N[C@H]2CCOC2=O)cc1 |r|
Show InChI InChI=1S/C14H14F3NO3/c15-14(16,17)10-4-1-9(2-5-10)3-6-12(19)18-11-7-8-21-13(11)20/h1-2,4-5,11H,3,6-8H2,(H,18,19)/t11-/m0/s1
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University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay


Bioorg Med Chem Lett 18: 5978-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.089
BindingDB Entry DOI: 10.7270/Q2Q81CXX
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri (strain ATCC 700601 / ES114))
BDBM50266311
PNG
((S)-2-(3-nitrophenoxy)-N-(2-oxotetrahydrofuran-3-y...)
Show SMILES [O-][N+](=O)c1cccc(OCC(=O)N[C@H]2CCOC2=O)c1 |r|
Show InChI InChI=1S/C12H12N2O6/c15-11(13-10-4-5-19-12(10)16)7-20-9-3-1-2-8(6-9)14(17)18/h1-3,6,10H,4-5,7H2,(H,13,15)/t10-/m0/s1
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University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay


Bioorg Med Chem Lett 18: 5978-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.089
BindingDB Entry DOI: 10.7270/Q2Q81CXX
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri (strain ATCC 700601 / ES114))
BDBM50266200
PNG
((S)-2-(3-methoxyphenyl)-N-(2-oxotetrahydrofuran-3-...)
Show SMILES COc1cccc(CC(=O)N[C@H]2CCOC2=O)c1 |r|
Show InChI InChI=1S/C13H15NO4/c1-17-10-4-2-3-9(7-10)8-12(15)14-11-5-6-18-13(11)16/h2-4,7,11H,5-6,8H2,1H3,(H,14,15)/t11-/m0/s1
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n/an/a 2.50E+3n/an/an/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay


Bioorg Med Chem Lett 18: 5978-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.089
BindingDB Entry DOI: 10.7270/Q2Q81CXX
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri (strain ATCC 700601 / ES114))
BDBM50265808
PNG
((S)-3-(4-fluorophenyl)-N-(2-oxotetrahydrofuran-3-y...)
Show SMILES Fc1ccc(CCC(=O)N[C@H]2CCOC2=O)cc1 |r|
Show InChI InChI=1S/C13H14FNO3/c14-10-4-1-9(2-5-10)3-6-12(16)15-11-7-8-18-13(11)17/h1-2,4-5,11H,3,6-8H2,(H,15,16)/t11-/m0/s1
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University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay


Bioorg Med Chem Lett 18: 5978-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.089
BindingDB Entry DOI: 10.7270/Q2Q81CXX
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri)
BDBM50350661
PNG
(CHEMBL1813553)
Show SMILES CCCCCCCCCCCCCCn1cc[n+](c1)C1c2ccccc2-c2ccccc12
Show InChI InChI=1S/C30H41N2/c1-2-3-4-5-6-7-8-9-10-11-12-17-22-31-23-24-32(25-31)30-28-20-15-13-18-26(28)27-19-14-16-21-29(27)30/h13-16,18-21,23-25,30H,2-12,17,22H2,1H3/q+1
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n/an/a 2.70E+3n/an/an/an/an/an/a



INSA Lyon

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri LuxR assessed as inhibition of 3-oxo-C6-HSL-induced quorum sensing activation mediated bioluminescence


Bioorg Med Chem 19: 4868-75 (2011)


Article DOI: 10.1016/j.bmc.2011.06.075
BindingDB Entry DOI: 10.7270/Q2CC112H
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri)
BDBM50373048
PNG
(CHEMBL184106)
Show SMILES CCCCCS(=O)(=O)NC1CCOC1=O
Show InChI InChI=1S/C9H17NO4S/c1-2-3-4-7-15(12,13)10-8-5-6-14-9(8)11/h8,10H,2-7H2,1H3
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n/an/a 3.00E+3n/an/an/an/an/an/a



INSA Lyon

Curated by ChEMBL


Assay Description
Antagonist activity at LuxR in Vibrio fischeri assessed as inhibition of N-3-oxos-hexanoyl-L-homoserine lactone induced luminescence


Bioorg Med Chem 16: 3550-6 (2008)


Article DOI: 10.1016/j.bmc.2008.02.023
BindingDB Entry DOI: 10.7270/Q2X63NTT
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri (strain ATCC 700601 / ES114))
BDBM50266272
PNG
((S)-2-(4-bromophenoxy)-N-(2-oxotetrahydrofuran-3-y...)
Show SMILES Brc1ccc(OCC(=O)N[C@H]2CCOC2=O)cc1 |r|
Show InChI InChI=1S/C12H12BrNO4/c13-8-1-3-9(4-2-8)18-7-11(15)14-10-5-6-17-12(10)16/h1-4,10H,5-7H2,(H,14,15)/t10-/m0/s1
KEGG

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n/an/a 3.00E+3n/an/an/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay


Bioorg Med Chem Lett 18: 5978-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.089
BindingDB Entry DOI: 10.7270/Q2Q81CXX
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri)
BDBM50350666
PNG
(CHEMBL1813558)
Show SMILES CCCCCCCCCCCCCCn1cc[n+](c1)C1CCCC1
Show InChI InChI=1S/C22H41N2/c1-2-3-4-5-6-7-8-9-10-11-12-15-18-23-19-20-24(21-23)22-16-13-14-17-22/h19-22H,2-18H2,1H3/q+1
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n/an/a 3.40E+3n/an/an/an/an/an/a



INSA Lyon

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri LuxR assessed as inhibition of 3-oxo-C6-HSL-induced quorum sensing activation mediated bioluminescence


Bioorg Med Chem 19: 4868-75 (2011)


Article DOI: 10.1016/j.bmc.2011.06.075
BindingDB Entry DOI: 10.7270/Q2CC112H
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri)
BDBM50373057
PNG
(CHEMBL261162)
Show SMILES CCCCNS(=O)(=O)NC1CCOC1=O
Show InChI InChI=1S/C8H16N2O4S/c1-2-3-5-9-15(12,13)10-7-4-6-14-8(7)11/h7,9-10H,2-6H2,1H3
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n/an/a 3.60E+3n/an/an/an/an/an/a



INSA Lyon

Curated by ChEMBL


Assay Description
Antagonist activity at LuxR in Vibrio fischeri assessed as inhibition of N-3-oxos-hexanoyl-L-homoserine lactone induced luminescence


Bioorg Med Chem 16: 3550-6 (2008)


Article DOI: 10.1016/j.bmc.2008.02.023
BindingDB Entry DOI: 10.7270/Q2X63NTT
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri)
BDBM50350659
PNG
(CHEMBL1813551)
Show SMILES CCCCCCCCCCn1cc[n+](c1)C1c2ccccc2-c2ccccc12
Show InChI InChI=1S/C26H33N2/c1-2-3-4-5-6-7-8-13-18-27-19-20-28(21-27)26-24-16-11-9-14-22(24)23-15-10-12-17-25(23)26/h9-12,14-17,19-21,26H,2-8,13,18H2,1H3/q+1
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n/an/a 4.00E+3n/an/an/an/an/an/a



INSA Lyon

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri LuxR assessed as inhibition of 3-oxo-C6-HSL-induced quorum sensing activation mediated bioluminescence


Bioorg Med Chem 19: 4868-75 (2011)


Article DOI: 10.1016/j.bmc.2011.06.075
BindingDB Entry DOI: 10.7270/Q2CC112H
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri)
BDBM50350669
PNG
(CHEMBL1813546)
Show SMILES CCCCCCCCCCn1cc[n+](c1)C(c1ccc(Cl)cc1Cl)c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C26H31Cl4N2/c1-2-3-4-5-6-7-8-9-14-31-15-16-32(19-31)26(22-12-10-20(27)17-24(22)29)23-13-11-21(28)18-25(23)30/h10-13,15-19,26H,2-9,14H2,1H3/q+1
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n/an/a 4.90E+3n/an/an/an/an/an/a



INSA Lyon

Curated by ChEMBL


Assay Description
Antagonist activity at Vibrio fischeri LuxR assessed as inhibition of 3-oxo-C6-HSL-induced quorum sensing activation mediated bioluminescence


Bioorg Med Chem 19: 4868-75 (2011)


Article DOI: 10.1016/j.bmc.2011.06.075
BindingDB Entry DOI: 10.7270/Q2CC112H
More data for this
Ligand-Target Pair
Transcriptional activator protein luxR


(Vibrio fischeri)
BDBM50373055
PNG
(CHEMBL408369)
Show SMILES CCCCCCNS(=O)(=O)NC1CCOC1=O |w:11.10|
Show InChI InChI=1S/C10H20N2O4S/c1-2-3-4-5-7-11-17(14,15)12-9-6-8-16-10(9)13/h9,11-12H,2-8H2,1H3
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n/an/a 5.00E+3n/an/an/an/an/an/a



INSA Lyon

Curated by ChEMBL


Assay Description
Antagonist activity at LuxR in Vibrio fischeri assessed as inhibition of N-3-oxos-hexanoyl-L-homoserine lactone induced luminescence


Bioorg Med Chem 16: 3550-6 (2008)


Article DOI: 10.1016/j.bmc.2008.02.023
BindingDB Entry DOI: 10.7270/Q2X63NTT
More data for this
Ligand-Target Pair
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