Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serine/threonine-protein kinase ATR (Homo sapiens (Human)) | BDBM97372 (US20130089624, 1) | PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.503 | -53.1 | 200 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Vertex Pharmaceuticals US Patent | Assay Description Compounds were screened for their ability to inhibit ATR kinase using a radioactive-phosphate incorporation assay. | US Patent US20130089624 (2013) BindingDB Entry DOI: 10.7270/Q2PZ57DN | |||||||||||
More data for this Ligand-Target Pair |