Affinity Data by Patent

Patent code US8497270

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Gag-Pol polyprotein (Human immunodeficiency virus type 1 (HIV-1))	BDBM98672 (US8497270, 35) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Elanco Animal Health Ireland Limited US Patent					Assay Description Inhibition of HIV integrase.				US Patent US8497270 (2013) BindingDB Entry DOI: 10.7270/Q2CC0Z9F
Elanco Animal Health Ireland Limited US Patent					More data for this Ligand-Target Pair
Gag-Pol polyprotein (Human immunodeficiency virus type 1 (HIV-1))	BDBM98668 (US8497270, 29) Show SMILES CNS(=O)(=O)CCCCN=[N]#N Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Elanco Animal Health Ireland Limited US Patent					Assay Description Inhibition of HIV integrase.				US Patent US8497270 (2013) BindingDB Entry DOI: 10.7270/Q2CC0Z9F
Elanco Animal Health Ireland Limited US Patent					More data for this Ligand-Target Pair
Gag-Pol polyprotein (Human immunodeficiency virus type 1 (HIV-1))	BDBM98669 (US8497270, 30) Show SMILES CNS(=O)(=O)CCCCN Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Elanco Animal Health Ireland Limited US Patent					Assay Description Inhibition of HIV integrase.				US Patent US8497270 (2013) BindingDB Entry DOI: 10.7270/Q2CC0Z9F
Elanco Animal Health Ireland Limited US Patent					More data for this Ligand-Target Pair
Gag-Pol polyprotein (Human immunodeficiency virus type 1 (HIV-1))	BDBM98665 (US8497270, 24) Show SMILES COC(=O)c1nc(Br)c2cccnc2c1OCc1ccccc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	950	n/a	n/a	n/a	n/a	n/a	n/a
Elanco Animal Health Ireland Limited US Patent					Assay Description Inhibition of HIV integrase.				US Patent US8497270 (2013) BindingDB Entry DOI: 10.7270/Q2CC0Z9F
Elanco Animal Health Ireland Limited US Patent					More data for this Ligand-Target Pair
Gag-Pol polyprotein (Human immunodeficiency virus type 1 (HIV-1))	BDBM98667 (US8497270, 28) Show SMILES CNS(=O)(=O)CCCCCl Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Elanco Animal Health Ireland Limited US Patent					Assay Description Inhibition of HIV integrase.				US Patent US8497270 (2013) BindingDB Entry DOI: 10.7270/Q2CC0Z9F
Elanco Animal Health Ireland Limited US Patent					More data for this Ligand-Target Pair
Gag-Pol polyprotein (Human immunodeficiency virus type 1 (HIV-1))	BDBM98670 (US8497270, 31) Show SMILES CNS(=O)(=O)CCCCNC(=O)OC(C)(C)C Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Elanco Animal Health Ireland Limited US Patent					Assay Description Inhibition of HIV integrase.				US Patent US8497270 (2013) BindingDB Entry DOI: 10.7270/Q2CC0Z9F
Elanco Animal Health Ireland Limited US Patent					More data for this Ligand-Target Pair
Gag-Pol polyprotein (Human immunodeficiency virus type 1 (HIV-1))	BDBM98671 (US8497270, 32) Show SMILES CNS(=O)(=O)CCCCC#N Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Elanco Animal Health Ireland Limited US Patent					Assay Description Inhibition of HIV integrase.				US Patent US8497270 (2013) BindingDB Entry DOI: 10.7270/Q2CC0Z9F
Elanco Animal Health Ireland Limited US Patent					More data for this Ligand-Target Pair
Gag-Pol polyprotein (Human immunodeficiency virus type 1 (HIV-1))	BDBM98666 (US8497270, 25) Show SMILES CCOC(=O)c1cc(F)ccc1C#N Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	6.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Elanco Animal Health Ireland Limited US Patent					Assay Description Inhibition of HIV integrase.				US Patent US8497270 (2013) BindingDB Entry DOI: 10.7270/Q2CC0Z9F
Elanco Animal Health Ireland Limited US Patent					More data for this Ligand-Target Pair

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* indicates data uncertainty>20%