Found 65 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100942
(US8524909, 129 | US8524909, 27)Show SMILES COc1cc(cc(C2CC2)c1C(=O)N[C@@H]1COCC[C@H]1N1CCCC1)C(F)(F)F |r| Show InChI InChI=1S/C21H27F3N2O3/c1-28-18-11-14(21(22,23)24)10-15(13-4-5-13)19(18)20(27)25-16-12-29-9-6-17(16)26-7-2-3-8-26/h10-11,13,16-17H,2-9,12H2,1H3,(H,25,27)/t16-,17-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 7.60 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100930
(US8524909, 119 | US8524909, 15 | US8524909, 48)Show SMILES FC(F)(F)c1cc(C2CC2)c(C(=O)N[C@@H]2COCC[C@H]2N2CCCC2)c(c1)C(F)(F)F |r| Show InChI InChI=1S/C21H24F6N2O2/c22-20(23,24)13-9-14(12-3-4-12)18(15(10-13)21(25,26)27)19(30)28-16-11-31-8-5-17(16)29-6-1-2-7-29/h9-10,12,16-17H,1-8,11H2,(H,28,30)/t16-,17-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 13.2 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100942
(US8524909, 129 | US8524909, 27)Show SMILES COc1cc(cc(C2CC2)c1C(=O)N[C@@H]1COCC[C@H]1N1CCCC1)C(F)(F)F |r| Show InChI InChI=1S/C21H27F3N2O3/c1-28-18-11-14(21(22,23)24)10-15(13-4-5-13)19(18)20(27)25-16-12-29-9-6-17(16)26-7-2-3-8-26/h10-11,13,16-17H,2-9,12H2,1H3,(H,25,27)/t16-,17-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 14.7 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100939
(US8524909, 127 | US8524909, 24)Show SMILES CCc1cc(cc(OC)c1C(=O)N[C@@H]1COCC[C@H]1N1CCCC1)C(F)(F)F |r| Show InChI InChI=1S/C20H27F3N2O3/c1-3-13-10-14(20(21,22)23)11-17(27-2)18(13)19(26)24-15-12-28-9-6-16(15)25-7-4-5-8-25/h10-11,15-16H,3-9,12H2,1-2H3,(H,24,26)/t15-,16-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 15.5 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100965
(US8524909, 47)Show SMILES FC(F)(F)c1cc(C2CC2)c(C(=O)N[C@H]2COCC[C@@H]2N2CCCC2)c(c1)C(F)(F)F |r| Show InChI InChI=1S/C21H24F6N2O2/c22-20(23,24)13-9-14(12-3-4-12)18(15(10-13)21(25,26)27)19(30)28-16-11-31-8-5-17(16)29-6-1-2-7-29/h9-10,12,16-17H,1-8,11H2,(H,28,30)/t16-,17-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100924
(US8524909, 113 | US8524909, 42 | US8524909, 9)Show SMILES CSc1cc(cc(c1C(=O)N[C@@H]1COCC[C@H]1N1CCCC1)C(F)(F)F)C(F)(F)F |r| Show InChI InChI=1S/C19H22F6N2O2S/c1-30-15-9-11(18(20,21)22)8-12(19(23,24)25)16(15)17(28)26-13-10-29-7-4-14(13)27-5-2-3-6-27/h8-9,13-14H,2-7,10H2,1H3,(H,26,28)/t13-,14-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 16.5 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100941
(US8524909, 26)Show SMILES CCc1cc(cc(C)c1C(=O)N[C@@H]1COCC[C@H]1N1CCCC1)C(F)(F)F |r| Show InChI InChI=1S/C20H27F3N2O2/c1-3-14-11-15(20(21,22)23)10-13(2)18(14)19(26)24-16-12-27-9-6-17(16)25-7-4-5-8-25/h10-11,16-17H,3-9,12H2,1-2H3,(H,24,26)/t16-,17-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 17.9 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100930
(US8524909, 119 | US8524909, 15 | US8524909, 48)Show SMILES FC(F)(F)c1cc(C2CC2)c(C(=O)N[C@@H]2COCC[C@H]2N2CCCC2)c(c1)C(F)(F)F |r| Show InChI InChI=1S/C21H24F6N2O2/c22-20(23,24)13-9-14(12-3-4-12)18(15(10-13)21(25,26)27)19(30)28-16-11-31-8-5-17(16)29-6-1-2-7-29/h9-10,12,16-17H,1-8,11H2,(H,28,30)/t16-,17-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100969
(US8524909, 51)Show SMILES Cc1cc(cc(C)c1C(=O)N[C@H]1COCC[C@@H]1N1CCCC1)C(F)(F)F |r| Show InChI InChI=1S/C19H25F3N2O2/c1-12-9-14(19(20,21)22)10-13(2)17(12)18(25)23-15-11-26-8-5-16(15)24-6-3-4-7-24/h9-10,15-16H,3-8,11H2,1-2H3,(H,23,25)/t15-,16-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 25.3 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100979
(US8524909, 133 | US8524909, 59)Show SMILES COc1cc(cc(SC)c1C(=O)N[C@@H]1COCC[C@H]1N1CCC2CC12)C(F)(F)F |r| Show InChI InChI=1S/C20H25F3N2O3S/c1-27-16-8-12(20(21,22)23)9-17(29-2)18(16)19(26)24-13-10-28-6-4-14(13)25-5-3-11-7-15(11)25/h8-9,11,13-15H,3-7,10H2,1-2H3,(H,24,26)/t11?,13-,14-,15?/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 26.4 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100950
(US8524909, 35)Show SMILES FC(F)(F)c1ccc(C(=O)N[C@@H]2COCC[C@H]2N2C[C@@H]3C[C@@H]3C2)c(c1)C1CC1 |r| Show InChI InChI=1S/C21H25F3N2O2/c22-21(23,24)15-3-4-16(17(8-15)12-1-2-12)20(27)25-18-11-28-6-5-19(18)26-9-13-7-14(13)10-26/h3-4,8,12-14,18-19H,1-2,5-7,9-11H2,(H,25,27)/t13-,14+,18-,19-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 26.5 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100924
(US8524909, 113 | US8524909, 42 | US8524909, 9)Show SMILES CSc1cc(cc(c1C(=O)N[C@@H]1COCC[C@H]1N1CCCC1)C(F)(F)F)C(F)(F)F |r| Show InChI InChI=1S/C19H22F6N2O2S/c1-30-15-9-11(18(20,21)22)8-12(19(23,24)25)16(15)17(28)26-13-10-29-7-4-14(13)27-5-2-3-6-27/h8-9,13-14H,2-7,10H2,1H3,(H,26,28)/t13-,14-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100986
(US8524909, 6)Show SMILES COc1cc(cc(SC)c1C(=O)N[C@@H]1COCC[C@H]1N1CCCC1)C(F)(F)F |r| Show InChI InChI=1S/C19H25F3N2O3S/c1-26-15-9-12(19(20,21)22)10-16(28-2)17(15)18(25)23-13-11-27-8-5-14(13)24-6-3-4-7-24/h9-10,13-14H,3-8,11H2,1-2H3,(H,23,25)/t13-,14-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 28.4 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100937
(US8524909, 125 | US8524909, 22)Show SMILES COc1cc(cc(C)c1C(=O)N[C@@H]1COCC[C@H]1N1CCCC1)C(F)(F)F |r| Show InChI InChI=1S/C19H25F3N2O3/c1-12-9-13(19(20,21)22)10-16(26-2)17(12)18(25)23-14-11-27-8-5-15(14)24-6-3-4-7-24/h9-10,14-15H,3-8,11H2,1-2H3,(H,23,25)/t14-,15-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 33.8 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100936
(US8524909, 123 | US8524909, 21)Show SMILES Cc1cc(cc(C)c1C(=O)N[C@@H]1COCC[C@H]1N1CCCC1)C(F)(F)F |r| Show InChI InChI=1S/C19H25F3N2O2/c1-12-9-14(19(20,21)22)10-13(2)17(12)18(25)23-15-11-26-8-5-16(15)24-6-3-4-7-24/h9-10,15-16H,3-8,11H2,1-2H3,(H,23,25)/t15-,16-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 34.1 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100923
(US8524909, 108 | US8524909, 37 | US8524909, 8)Show SMILES FC(F)(F)c1ccc(C(=O)N[C@@H]2COCC[C@H]2N2CCCC2)c(c1)C1CC1 |r| Show InChI InChI=1S/C20H25F3N2O2/c21-20(22,23)14-5-6-15(16(11-14)13-3-4-13)19(26)24-17-12-27-10-7-18(17)25-8-1-2-9-25/h5-6,11,13,17-18H,1-4,7-10,12H2,(H,24,26)/t17-,18-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 36.3 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100925
(US8524909, 10 | US8524909, 111 | US8524909, 40)Show SMILES Cc1cc(cc(c1C(=O)N[C@@H]1COCC[C@H]1N1CCCC1)C(F)(F)F)C(F)(F)F |r| Show InChI InChI=1S/C19H22F6N2O2/c1-11-8-12(18(20,21)22)9-13(19(23,24)25)16(11)17(28)26-14-10-29-7-4-15(14)27-5-2-3-6-27/h8-9,14-15H,2-7,10H2,1H3,(H,26,28)/t14-,15-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 41.2 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100957
(US8524909, 39)Show SMILES Cc1cc(cc(c1C(=O)N[C@H]1COCC[C@@H]1N1CCCC1)C(F)(F)F)C(F)(F)F |r| Show InChI InChI=1S/C19H22F6N2O2/c1-11-8-12(18(20,21)22)9-13(19(23,24)25)16(11)17(28)26-14-10-29-7-4-15(14)27-5-2-3-6-27/h8-9,14-15H,2-7,10H2,1H3,(H,26,28)/t14-,15-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 43.9 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100959
(US8524909, 41)Show SMILES CSc1cc(cc(c1C(=O)N[C@H]1COCC[C@@H]1N1CCCC1)C(F)(F)F)C(F)(F)F |r| Show InChI InChI=1S/C19H22F6N2O2S/c1-30-15-9-11(18(20,21)22)8-12(19(23,24)25)16(15)17(28)26-13-10-29-7-4-14(13)27-5-2-3-6-27/h8-9,13-14H,2-7,10H2,1H3,(H,26,28)/t13-,14-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 44.7 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100936
(US8524909, 123 | US8524909, 21)Show SMILES Cc1cc(cc(C)c1C(=O)N[C@@H]1COCC[C@H]1N1CCCC1)C(F)(F)F |r| Show InChI InChI=1S/C19H25F3N2O2/c1-12-9-14(19(20,21)22)10-13(2)17(12)18(25)23-15-11-26-8-5-16(15)24-6-3-4-7-24/h9-10,15-16H,3-8,11H2,1-2H3,(H,23,25)/t15-,16-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 45.2 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100973
(US8524909, 55)Show SMILES CCc1cc(cc(OC)c1C(=O)N[C@H]1COCC[C@@H]1N1CCCC1)C(F)(F)F |r| Show InChI InChI=1S/C20H27F3N2O3/c1-3-13-10-14(20(21,22)23)11-17(27-2)18(13)19(26)24-15-12-28-9-6-16(15)25-7-4-5-8-25/h10-11,15-16H,3-9,12H2,1-2H3,(H,24,26)/t15-,16-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 48.3 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100968
(US8524909, 50)Show SMILES FC(F)(F)c1ccc(C(=O)N[C@H]2COCC[C@@H]2NC2CCCCC2)c(c1)C1CC1 |r| Show InChI InChI=1S/C22H29F3N2O2/c23-22(24,25)15-8-9-17(18(12-15)14-6-7-14)21(28)27-20-13-29-11-10-19(20)26-16-4-2-1-3-5-16/h8-9,12,14,16,19-20,26H,1-7,10-11,13H2,(H,27,28)/t19-,20-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 57 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100938
(US8524909, 23)Show SMILES CCc1cc(cc(CC)c1C(=O)N[C@@H]1COCC[C@H]1N1CCCC1)C(F)(F)F |r| Show InChI InChI=1S/C21H29F3N2O2/c1-3-14-11-16(21(22,23)24)12-15(4-2)19(14)20(27)25-17-13-28-10-7-18(17)26-8-5-6-9-26/h11-12,17-18H,3-10,13H2,1-2H3,(H,25,27)/t17-,18-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 58.4 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100975
(US8524909, 57)Show SMILES COc1cc(cc(C2CC2)c1C(=O)N[C@H]1COCC[C@@H]1N1CCCC1)C(F)(F)F |r| Show InChI InChI=1S/C21H27F3N2O3/c1-28-18-11-14(21(22,23)24)10-15(13-4-5-13)19(18)20(27)25-16-12-29-9-6-17(16)26-7-2-3-8-26/h10-11,13,16-17H,2-9,12H2,1H3,(H,25,27)/t16-,17-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 62.5 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100939
(US8524909, 127 | US8524909, 24)Show SMILES CCc1cc(cc(OC)c1C(=O)N[C@@H]1COCC[C@H]1N1CCCC1)C(F)(F)F |r| Show InChI InChI=1S/C20H27F3N2O3/c1-3-13-10-14(20(21,22)23)11-17(27-2)18(13)19(26)24-15-12-28-9-6-16(15)25-7-4-5-8-25/h10-11,15-16H,3-9,12H2,1-2H3,(H,24,26)/t15-,16-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 64.1 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100921
(US8524909, 2 | US8524909, 5)Show SMILES COc1cc(cc(SC)c1C(=O)N[C@H]1COCC[C@@H]1N1CCCC1)C(F)(F)F |r| Show InChI InChI=1S/C19H25F3N2O3S/c1-26-15-9-12(19(20,21)22)10-16(28-2)17(15)18(25)23-13-11-27-8-5-14(13)24-6-3-4-7-24/h9-10,13-14H,3-8,11H2,1-2H3,(H,23,25)/t13-,14-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 66.2 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100927
(US8524909, 115 | US8524909, 12 | US8524909, 44)Show SMILES FC(F)(F)c1ccc(C(=O)N[C@@H]2COCC[C@H]2NC2CCCC2)c(c1)C1CC1 |r| Show InChI InChI=1S/C21H27F3N2O2/c22-21(23,24)14-7-8-16(17(11-14)13-5-6-13)20(27)26-19-12-28-10-9-18(19)25-15-3-1-2-4-15/h7-8,11,13,15,18-19,25H,1-6,9-10,12H2,(H,26,27)/t18-,19-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 75 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100971
(US8524909, 53)Show SMILES COc1cc(cc(C)c1C(=O)N[C@H]1COCC[C@@H]1N1CCCC1)C(F)(F)F |r| Show InChI InChI=1S/C19H25F3N2O3/c1-12-9-13(19(20,21)22)10-16(26-2)17(12)18(25)23-14-11-27-8-5-15(14)24-6-3-4-7-24/h9-10,14-15H,3-8,11H2,1-2H3,(H,23,25)/t14-,15-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 78.2 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100961
(US8524909, 43)Show SMILES FC(F)(F)c1ccc(C(=O)N[C@H]2COCC[C@@H]2NC2CCCC2)c(c1)C1CC1 |r| Show InChI InChI=1S/C21H27F3N2O2/c22-21(23,24)14-7-8-16(17(11-14)13-5-6-13)20(27)26-19-12-28-10-9-18(19)25-15-3-1-2-4-15/h7-8,11,13,15,18-19,25H,1-6,9-10,12H2,(H,26,27)/t18-,19-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 78.8 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100934
(US8524909, 19)Show SMILES FC(F)(F)c1ccc(C(=O)N[C@@H]2COCC[C@H]2N2CCCCC2)c(c1)C1CC1 |r| Show InChI InChI=1S/C21H27F3N2O2/c22-21(23,24)15-6-7-16(17(12-15)14-4-5-14)20(27)25-18-13-28-11-8-19(18)26-9-2-1-3-10-26/h6-7,12,14,18-19H,1-5,8-11,13H2,(H,25,27)/t18-,19-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 81.5 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100923
(US8524909, 108 | US8524909, 37 | US8524909, 8)Show SMILES FC(F)(F)c1ccc(C(=O)N[C@@H]2COCC[C@H]2N2CCCC2)c(c1)C1CC1 |r| Show InChI InChI=1S/C20H25F3N2O2/c21-20(22,23)14-5-6-15(16(11-14)13-3-4-13)19(26)24-17-12-27-10-7-18(17)25-8-1-2-9-25/h5-6,11,13,17-18H,1-4,7-10,12H2,(H,24,26)/t17-,18-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 83.4 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100956
(US8524909, 38)Show SMILES FC(F)(F)c1ccc(C(=O)N[C@H]2COCC[C@@H]2N2CCCC2)c(c1)C1CC1 |r| Show InChI InChI=1S/C20H25F3N2O2/c21-20(22,23)14-5-6-15(16(11-14)13-3-4-13)19(26)24-17-12-27-10-7-18(17)25-8-1-2-9-25/h5-6,11,13,17-18H,1-4,7-10,12H2,(H,24,26)/t17-,18-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 83.4 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100945
(US8524909, 30)Show SMILES CC(N[C@@H]1CCOC[C@H]1NC(=O)c1ccc(cc1C1CC1)C(F)(F)F)C1CC1 |r| Show InChI InChI=1S/C21H27F3N2O2/c1-12(13-2-3-13)25-18-8-9-28-11-19(18)26-20(27)16-7-6-15(21(22,23)24)10-17(16)14-4-5-14/h6-7,10,12-14,18-19,25H,2-5,8-9,11H2,1H3,(H,26,27)/t12?,18-,19-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 83.8 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100925
(US8524909, 10 | US8524909, 111 | US8524909, 40)Show SMILES Cc1cc(cc(c1C(=O)N[C@@H]1COCC[C@H]1N1CCCC1)C(F)(F)F)C(F)(F)F |r| Show InChI InChI=1S/C19H22F6N2O2/c1-11-8-12(18(20,21)22)9-13(19(23,24)25)16(11)17(28)26-14-10-29-7-4-15(14)27-5-2-3-6-27/h8-9,14-15H,2-7,10H2,1H3,(H,26,28)/t14-,15-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 95.5 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100937
(US8524909, 125 | US8524909, 22)Show SMILES COc1cc(cc(C)c1C(=O)N[C@@H]1COCC[C@H]1N1CCCC1)C(F)(F)F |r| Show InChI InChI=1S/C19H25F3N2O3/c1-12-9-13(19(20,21)22)10-16(26-2)17(12)18(25)23-14-11-27-8-5-15(14)24-6-3-4-7-24/h9-10,14-15H,3-8,11H2,1-2H3,(H,23,25)/t14-,15-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 105 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100949
(US8524909, 34)Show SMILES COc1cc(cc(SC)c1C(=O)N[C@@H]1COCC[C@H]1N1C[C@@H]2C[C@@H]2C1)C(F)(F)F |r| Show InChI InChI=1S/C20H25F3N2O3S/c1-27-16-6-13(20(21,22)23)7-17(29-2)18(16)19(26)24-14-10-28-4-3-15(14)25-8-11-5-12(11)9-25/h6-7,11-12,14-15H,3-5,8-10H2,1-2H3,(H,24,26)/t11-,12+,14-,15-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100963
(US8524909, 45)Show SMILES COc1cc(cc(SC)c1C(=O)N[C@H]1COCC[C@@H]1NC1CCCC1)C(F)(F)F |r| Show InChI InChI=1S/C20H27F3N2O3S/c1-27-16-9-12(20(21,22)23)10-17(29-2)18(16)19(26)25-15-11-28-8-7-14(15)24-13-5-3-4-6-13/h9-10,13-15,24H,3-8,11H2,1-2H3,(H,25,26)/t14-,15-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 111 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100979
(US8524909, 133 | US8524909, 59)Show SMILES COc1cc(cc(SC)c1C(=O)N[C@@H]1COCC[C@H]1N1CCC2CC12)C(F)(F)F |r| Show InChI InChI=1S/C20H25F3N2O3S/c1-27-16-8-12(20(21,22)23)9-17(29-2)18(16)19(26)24-13-10-28-6-4-14(13)25-5-3-11-7-15(11)25/h8-9,11,13-15H,3-7,10H2,1-2H3,(H,24,26)/t11?,13-,14-,15?/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 114 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100921
(US8524909, 2 | US8524909, 5)Show SMILES COc1cc(cc(SC)c1C(=O)N[C@H]1COCC[C@@H]1N1CCCC1)C(F)(F)F |r| Show InChI InChI=1S/C19H25F3N2O3S/c1-26-15-9-12(19(20,21)22)10-16(28-2)17(15)18(25)23-13-11-27-8-5-14(13)24-6-3-4-7-24/h9-10,13-14H,3-8,11H2,1-2H3,(H,23,25)/t13-,14-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 118 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100978
(US8524909, 136 | US8524909, 63 | US8524909, 65)Show SMILES COc1cc(cc(SC)c1C(=O)N[C@@H]1CCOC[C@@H]1N1CCCC1)C(F)(F)F |r| Show InChI InChI=1S/C19H25F3N2O3S/c1-26-15-9-12(19(20,21)22)10-16(28-2)17(15)18(25)23-13-5-8-27-11-14(13)24-6-3-4-7-24/h9-10,13-14H,3-8,11H2,1-2H3,(H,23,25)/t13-,14+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 119 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100947
(US8524909, 32)Show SMILES FC(F)(F)c1ccc(C(=O)N[C@@H]2COCC[C@H]2NC2CCC2)c(c1)C1CC1 Show InChI InChI=1S/C20H25F3N2O2/c21-20(22,23)13-6-7-15(16(10-13)12-4-5-12)19(26)25-18-11-27-9-8-17(18)24-14-2-1-3-14/h6-7,10,12,14,17-18,24H,1-5,8-9,11H2,(H,25,26)/t17-,18-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 119 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100929
(US8524909, 120 | US8524909, 14 | US8524909, 49)Show SMILES FC(F)(F)c1ccc(C(=O)N[C@@H]2COCC[C@H]2NC2CCCCC2)c(c1)C1CC1 |r| Show InChI InChI=1S/C22H29F3N2O2/c23-22(24,25)15-8-9-17(18(12-15)14-6-7-14)21(28)27-20-13-29-11-10-19(20)26-16-4-2-1-3-5-16/h8-9,12,14,16,19-20,26H,1-7,10-11,13H2,(H,27,28)/t19-,20-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 125 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100933
(US8524909, 18)Show SMILES FC(F)(F)c1ccc(C(=O)N[C@@H]2COCC[C@H]2NCC2CC2)c(c1)C1CC1 |r| Show InChI InChI=1S/C20H25F3N2O2/c21-20(22,23)14-5-6-15(16(9-14)13-3-4-13)19(26)25-18-11-27-8-7-17(18)24-10-12-1-2-12/h5-6,9,12-13,17-18,24H,1-4,7-8,10-11H2,(H,25,26)/t17-,18-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 126 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100926
(US8524909, 11 | US8524909, 117 | US8524909, 46)Show SMILES COc1cc(cc(SC)c1C(=O)N[C@@H]1COCC[C@H]1NC1CCCC1)C(F)(F)F |r| Show InChI InChI=1S/C20H27F3N2O3S/c1-27-16-9-12(20(21,22)23)10-17(29-2)18(16)19(26)25-15-11-28-8-7-14(15)24-13-5-3-4-6-13/h9-10,13-15,24H,3-8,11H2,1-2H3,(H,25,26)/t14-,15-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 127 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100943
(US8524909, 28)Show SMILES COc1cc(cc(SC)c1C(=O)N[C@@H]1COCC[C@H]1NC1(C)CCCC1)C(F)(F)F |r| Show InChI InChI=1S/C21H29F3N2O3S/c1-20(7-4-5-8-20)26-14-6-9-29-12-15(14)25-19(27)18-16(28-2)10-13(21(22,23)24)11-17(18)30-3/h10-11,14-15,26H,4-9,12H2,1-3H3,(H,25,27)/t14-,15-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 144 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100922
(US8524909, 7)Show SMILES COc1cc(cc(SC)c1C(=O)N[C@H]1COCC[C@@H]1N1CCC(O)C1)C(F)(F)F |r| Show InChI InChI=1S/C19H25F3N2O4S/c1-27-15-7-11(19(20,21)22)8-16(29-2)17(15)18(26)23-13-10-28-6-4-14(13)24-5-3-12(25)9-24/h7-8,12-14,25H,3-6,9-10H2,1-2H3,(H,23,26)/t12?,13-,14-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 155 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100926
(US8524909, 11 | US8524909, 117 | US8524909, 46)Show SMILES COc1cc(cc(SC)c1C(=O)N[C@@H]1COCC[C@H]1NC1CCCC1)C(F)(F)F |r| Show InChI InChI=1S/C20H27F3N2O3S/c1-27-16-9-12(20(21,22)23)10-17(29-2)18(16)19(26)25-15-11-28-8-7-14(15)24-13-5-3-4-6-13/h9-10,13-15,24H,3-8,11H2,1-2H3,(H,25,26)/t14-,15-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 158 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100978
(US8524909, 136 | US8524909, 63 | US8524909, 65)Show SMILES COc1cc(cc(SC)c1C(=O)N[C@@H]1CCOC[C@@H]1N1CCCC1)C(F)(F)F |r| Show InChI InChI=1S/C19H25F3N2O3S/c1-26-15-9-12(19(20,21)22)10-16(28-2)17(15)18(25)23-13-5-8-27-11-14(13)24-6-3-4-7-24/h9-10,13-14H,3-8,11H2,1-2H3,(H,23,25)/t13-,14+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 189 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100977
(US8524909, 64)Show SMILES COc1cc(cc(SC)c1C(=O)N[C@H]1CCOC[C@H]1N1CCCC1)C(F)(F)F |r| Show InChI InChI=1S/C19H25F3N2O3S/c1-26-15-9-12(19(20,21)22)10-16(28-2)17(15)18(25)23-13-5-8-27-11-14(13)24-6-3-4-7-24/h9-10,13-14H,3-8,11H2,1-2H3,(H,23,25)/t13-,14+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 189 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100935
(US8524909, 20)Show SMILES FC(F)(F)c1ccc(C(=O)N[C@@H]2COCC[C@H]2NC2CC2)c(c1)C1CC1 |r| Show InChI InChI=1S/C19H23F3N2O2/c20-19(21,22)12-3-6-14(15(9-12)11-1-2-11)18(25)24-17-10-26-8-7-16(17)23-13-4-5-13/h3,6,9,11,13,16-17,23H,1-2,4-5,7-8,10H2,(H,24,25)/t16-,17-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 194 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100944
(US8524909, 29)Show SMILES CC1(CCCC1)N[C@@H]1CCOC[C@H]1NC(=O)c1ccc(cc1C1CC1)C(F)(F)F |r| Show InChI InChI=1S/C22H29F3N2O2/c1-21(9-2-3-10-21)27-18-8-11-29-13-19(18)26-20(28)16-7-6-15(22(23,24)25)12-17(16)14-4-5-14/h6-7,12,14,18-19,27H,2-5,8-11,13H2,1H3,(H,26,28)/t18-,19-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 235 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100928
(US8524909, 13)Show SMILES CSc1cc(cc(c1C(=O)N[C@@H]1COCC[C@H]1NC1CCCC1)C(F)(F)F)C(F)(F)F |r| Show InChI InChI=1S/C20H24F6N2O2S/c1-31-16-9-11(19(21,22)23)8-13(20(24,25)26)17(16)18(29)28-15-10-30-7-6-14(15)27-12-4-2-3-5-12/h8-9,12,14-15,27H,2-7,10H2,1H3,(H,28,29)/t14-,15-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100919
(US8524909, 1)Show SMILES COc1cc(cc(SC)c1C(=O)N[C@H]1COCC[C@H]1N1CCCC1)C(F)(F)F |r| Show InChI InChI=1S/C19H25F3N2O3S/c1-26-15-9-12(19(20,21)22)10-16(28-2)17(15)18(25)23-13-11-27-8-5-14(13)24-6-3-4-7-24/h9-10,13-14H,3-8,11H2,1-2H3,(H,23,25)/t13-,14+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 261 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100951
(US8524909, 36)Show SMILES OC1CCN(CC1)[C@@H]1CCOC[C@H]1NC(=O)c1ccc(cc1C1CC1)C(F)(F)F |r| Show InChI InChI=1S/C21H27F3N2O3/c22-21(23,24)14-3-4-16(17(11-14)13-1-2-13)20(28)25-18-12-29-10-7-19(18)26-8-5-15(27)6-9-26/h3-4,11,13,15,18-19,27H,1-2,5-10,12H2,(H,25,28)/t18-,19-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 274 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100946
(US8524909, 31)Show SMILES COc1cc(cc(SC)c1C(=O)N[C@@H]1COCC[C@H]1NC(C)C1CC1)C(F)(F)F |r| Show InChI InChI=1S/C20H27F3N2O3S/c1-11(12-4-5-12)24-14-6-7-28-10-15(14)25-19(26)18-16(27-2)8-13(20(21,22)23)9-17(18)29-3/h8-9,11-12,14-15,24H,4-7,10H2,1-3H3,(H,25,26)/t11?,14-,15-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 276 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100940
(US8524909, 25)Show SMILES COc1cc(cc(SC)c1C(=O)N[C@@H]1COCC[C@H]1NC1(C)CCCCC1)C(F)(F)F |r| Show InChI InChI=1S/C22H31F3N2O3S/c1-21(8-5-4-6-9-21)27-15-7-10-30-13-16(15)26-20(28)19-17(29-2)11-14(22(23,24)25)12-18(19)31-3/h11-12,15-16,27H,4-10,13H2,1-3H3,(H,26,28)/t15-,16-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 278 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100981
(US8524909, 135 | US8524909, 61)Show SMILES OC1CCN(C1)[C@@H]1CCOC[C@H]1NC(=O)c1ccc(cc1C1CC1)C(F)(F)F |r| Show InChI InChI=1S/C20H25F3N2O3/c21-20(22,23)13-3-4-15(16(9-13)12-1-2-12)19(27)24-17-11-28-8-6-18(17)25-7-5-14(26)10-25/h3-4,9,12,14,17-18,26H,1-2,5-8,10-11H2,(H,24,27)/t14?,17-,18-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 282 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100931
(US8524909, 16)Show SMILES CC(C)N[C@@H]1CCOC[C@H]1NC(=O)c1ccc(cc1C1CC1)C(F)(F)F |r| Show InChI InChI=1S/C19H25F3N2O2/c1-11(2)23-16-7-8-26-10-17(16)24-18(25)14-6-5-13(19(20,21)22)9-15(14)12-3-4-12/h5-6,9,11-12,16-17,23H,3-4,7-8,10H2,1-2H3,(H,24,25)/t16-,17-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 296 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100927
(US8524909, 115 | US8524909, 12 | US8524909, 44)Show SMILES FC(F)(F)c1ccc(C(=O)N[C@@H]2COCC[C@H]2NC2CCCC2)c(c1)C1CC1 |r| Show InChI InChI=1S/C21H27F3N2O2/c22-21(23,24)14-7-8-16(17(11-14)13-5-6-13)20(27)26-19-12-28-10-9-18(19)25-15-3-1-2-4-15/h7-8,11,13,15,18-19,25H,1-6,9-10,12H2,(H,26,27)/t18-,19-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 299 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100985
(US8524909, 4)Show SMILES COc1cc(cc(SC)c1C(=O)N[C@H]1COCC[C@@H]1NC1CCC1)C(F)(F)F |r| Show InChI InChI=1S/C19H25F3N2O3S/c1-26-15-8-11(19(20,21)22)9-16(28-2)17(15)18(25)24-14-10-27-7-6-13(14)23-12-4-3-5-12/h8-9,12-14,23H,3-7,10H2,1-2H3,(H,24,25)/t13-,14-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 338 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100929
(US8524909, 120 | US8524909, 14 | US8524909, 49)Show SMILES FC(F)(F)c1ccc(C(=O)N[C@@H]2COCC[C@H]2NC2CCCCC2)c(c1)C1CC1 |r| Show InChI InChI=1S/C22H29F3N2O2/c23-22(24,25)15-8-9-17(18(12-15)14-6-7-14)21(28)27-20-13-29-11-10-19(20)26-16-4-2-1-3-5-16/h8-9,12,14,16,19-20,26H,1-7,10-11,13H2,(H,27,28)/t19-,20-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100981
(US8524909, 135 | US8524909, 61)Show SMILES OC1CCN(C1)[C@@H]1CCOC[C@H]1NC(=O)c1ccc(cc1C1CC1)C(F)(F)F |r| Show InChI InChI=1S/C20H25F3N2O3/c21-20(22,23)13-3-4-15(16(9-13)12-1-2-12)19(27)24-17-11-28-8-6-18(17)25-7-5-14(26)10-25/h3-4,9,12,14,17-18,26H,1-2,5-8,10-11H2,(H,24,27)/t14?,17-,18-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 348 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100920
(US8524909, 3)Show SMILES COc1cc(cc(SC)c1C(=O)N[C@H]1COCC[C@H]1NC1CCC1)C(F)(F)F |r| Show InChI InChI=1S/C19H25F3N2O3S/c1-26-15-8-11(19(20,21)22)9-16(28-2)17(15)18(25)24-14-10-27-7-6-13(14)23-12-4-3-5-12/h8-9,12-14,23H,3-7,10H2,1-2H3,(H,24,25)/t13-,14+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 506 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100948
(US8524909, 33)Show SMILES COc1cc(cc(SC)c1C(=O)N[C@@H]1COCC[C@H]1NC1CCC(O)CC1)C(F)(F)F |r,wU:18.20,wD:13.13,(1.33,3.08,;1.33,1.54,;2.67,.77,;4,1.54,;5.33,.77,;5.33,-.77,;4,-1.54,;4,-3.08,;5.33,-3.85,;2.67,-.77,;1.33,-1.54,;1.33,-3.08,;,-.77,;-1.33,-1.54,;-1.33,-3.08,;-2.67,-3.85,;-4,-3.08,;-4,-1.54,;-2.67,-.77,;-2.67,.77,;-4,1.54,;-4,3.08,;-5.33,3.85,;-6.67,3.08,;-8,3.85,;-6.67,1.54,;-5.33,.77,;6.67,1.54,;8,2.31,;6.67,3.08,;8,.77,)| Show InChI InChI=1S/C21H29F3N2O4S/c1-29-17-9-12(21(22,23)24)10-18(31-2)19(17)20(28)26-16-11-30-8-7-15(16)25-13-3-5-14(27)6-4-13/h9-10,13-16,25,27H,3-8,11H2,1-2H3,(H,26,28)/t13?,14?,15-,16-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 751 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Sodium- and chloride-dependent glycine transporter 1
(Bos taurus (Bovine)) | BDBM100932
(US8524909, 17)Show SMILES FC(F)(F)c1ccc(C(=O)N[C@@H]2COCC[C@H]2NC2CCOCC2)c(c1)C1CC1 |r| Show InChI InChI=1S/C21H27F3N2O3/c22-21(23,24)14-3-4-16(17(11-14)13-1-2-13)20(27)26-19-12-29-10-7-18(19)25-15-5-8-28-9-6-15/h3-4,11,13,15,18-19,25H,1-2,5-10,12H2,(H,26,27)/t18-,19-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 904 | n/a | n/a | n/a | n/a | n/a | 0 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
Glycine uptake inhibition assay. |
US Patent US8524909 (2013)
BindingDB Entry DOI: 10.7270/Q2QJ7FXS |
More data for this
Ligand-Target Pair | |
Search and Browse
