Found 23 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
C-C chemokine receptor type 1
(Homo sapiens (Human)) | BDBM102335
(US8536198, 106)Show SMILES C[C@H](NC(=O)N[C@@H]1CCCC[C@@H]1C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1)C(C)(C)O |r| Show InChI InChI=1S/C26H40ClN3O4/c1-17(25(4,5)33)28-23(32)29-21-9-7-6-8-20(21)22(31)30-15-14-26(34,24(2,3)16-30)18-10-12-19(27)13-11-18/h10-13,17,20-21,33-34H,6-9,14-16H2,1-5H3,(H2,28,29,32)/t17-,20-,21+,26-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| Assay Description
CCR1 ligand binding using scintillation proximity assay (SPA). |
US Patent US8536198 (2013)
BindingDB Entry DOI: 10.7270/Q2HT2MZ9 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 1
(Homo sapiens (Human)) | BDBM102327
(US8536198, 80)Show SMILES CC1(C)CN(CC[C@]1(O)c1ccc(Cl)cc1)C(=O)[C@H]1CCC[C@H]1NC(=O)c1cccc(c1)S(N)(=O)=O |r| Show InChI InChI=1S/C26H32ClN3O5S/c1-25(2)16-30(14-13-26(25,33)18-9-11-19(27)12-10-18)24(32)21-7-4-8-22(21)29-23(31)17-5-3-6-20(15-17)36(28,34)35/h3,5-6,9-12,15,21-22,33H,4,7-8,13-14,16H2,1-2H3,(H,29,31)(H2,28,34,35)/t21-,22+,26-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| Assay Description
CCR1 ligand binding using scintillation proximity assay (SPA). |
US Patent US8536198 (2013)
BindingDB Entry DOI: 10.7270/Q2HT2MZ9 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 1
(Homo sapiens (Human)) | BDBM102331
(US8536198, 86)Show SMILES CC1(C)CN(CC[C@]1(O)c1ccc(Cl)cc1)C(=O)[C@H]1CCC[C@H]1NC(=O)C1CCCC1 |r| Show InChI InChI=1S/C25H35ClN2O3/c1-24(2)16-28(15-14-25(24,31)18-10-12-19(26)13-11-18)23(30)20-8-5-9-21(20)27-22(29)17-6-3-4-7-17/h10-13,17,20-21,31H,3-9,14-16H2,1-2H3,(H,27,29)/t20-,21+,25-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| Assay Description
CCR1 ligand binding using scintillation proximity assay (SPA). |
US Patent US8536198 (2013)
BindingDB Entry DOI: 10.7270/Q2HT2MZ9 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 1
(Homo sapiens (Human)) | BDBM102329
(US8536198, 84)Show SMILES CC1(C)CN(CC[C@]1(O)c1ccc(Cl)cc1)C(=O)[C@H]1CCC[C@H]1NC(=O)[C@H]1CC[C@@H](O)C1 |r| Show InChI InChI=1S/C25H35ClN2O4/c1-24(2)15-28(13-12-25(24,32)17-7-9-18(26)10-8-17)23(31)20-4-3-5-21(20)27-22(30)16-6-11-19(29)14-16/h7-10,16,19-21,29,32H,3-6,11-15H2,1-2H3,(H,27,30)/t16-,19+,20-,21+,25-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| Assay Description
CCR1 ligand binding using scintillation proximity assay (SPA). |
US Patent US8536198 (2013)
BindingDB Entry DOI: 10.7270/Q2HT2MZ9 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 1
(Homo sapiens (Human)) | BDBM102330
(US8536198, 85)Show SMILES CC1(C)CN(CC[C@]1(O)c1ccc(Cl)cc1)C(=O)[C@H]1CCC[C@H]1NC(=O)c1cccc(c1)C(O)=O |r| Show InChI InChI=1S/C27H31ClN2O5/c1-26(2)16-30(14-13-27(26,35)19-9-11-20(28)12-10-19)24(32)21-7-4-8-22(21)29-23(31)17-5-3-6-18(15-17)25(33)34/h3,5-6,9-12,15,21-22,35H,4,7-8,13-14,16H2,1-2H3,(H,29,31)(H,33,34)/t21-,22+,27-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| Assay Description
CCR1 ligand binding using scintillation proximity assay (SPA). |
US Patent US8536198 (2013)
BindingDB Entry DOI: 10.7270/Q2HT2MZ9 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 1
(Homo sapiens (Human)) | BDBM102332
(US8536198, 89)Show SMILES CC1(C)CN(CC[C@]1(O)c1ccc(Cl)cc1)C(=O)[C@H]1CCC[C@H]1NC(=O)c1cccc(c1)C(N)=O |r| Show InChI InChI=1S/C27H32ClN3O4/c1-26(2)16-31(14-13-27(26,35)19-9-11-20(28)12-10-19)25(34)21-7-4-8-22(21)30-24(33)18-6-3-5-17(15-18)23(29)32/h3,5-6,9-12,15,21-22,35H,4,7-8,13-14,16H2,1-2H3,(H2,29,32)(H,30,33)/t21-,22+,27-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| Assay Description
CCR1 ligand binding using scintillation proximity assay (SPA). |
US Patent US8536198 (2013)
BindingDB Entry DOI: 10.7270/Q2HT2MZ9 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 1
(Homo sapiens (Human)) | BDBM102313
(US8536198, 2)Show SMILES CC1(C)CN(CC[C@]1(O)c1ccc(Cl)cc1)C(=O)[C@H]1CCCC[C@H]1NC(=O)c1ccccc1 |r| Show InChI InChI=1S/C27H33ClN2O3/c1-26(2)18-30(17-16-27(26,33)20-12-14-21(28)15-13-20)25(32)22-10-6-7-11-23(22)29-24(31)19-8-4-3-5-9-19/h3-5,8-9,12-15,22-23,33H,6-7,10-11,16-18H2,1-2H3,(H,29,31)/t22-,23+,27-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| Assay Description
CCR1 ligand binding using scintillation proximity assay (SPA). |
US Patent US8536198 (2013)
BindingDB Entry DOI: 10.7270/Q2HT2MZ9 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 1
(Homo sapiens (Human)) | BDBM102333
(US8536198, 100)Show SMILES CC1(C)CN(CC[C@]1(O)c1ccc(cc1)[N+]#[C-])C(=O)[C@H]1CCCC[C@H]1NC(=O)c1cccc(c1)C(O)=O |r| Show InChI InChI=1S/C29H33N3O5/c1-28(2)18-32(16-15-29(28,37)21-11-13-22(30-3)14-12-21)26(34)23-9-4-5-10-24(23)31-25(33)19-7-6-8-20(17-19)27(35)36/h6-8,11-14,17,23-24,37H,4-5,9-10,15-16,18H2,1-2H3,(H,31,33)(H,35,36)/t23-,24+,29-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 11.3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| Assay Description
CCR1 ligand binding using scintillation proximity assay (SPA). |
US Patent US8536198 (2013)
BindingDB Entry DOI: 10.7270/Q2HT2MZ9 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 1
(Homo sapiens (Human)) | BDBM102315
(US8536198, 9)Show SMILES CC1(C)CN(CC[C@]1(O)c1ccc(Cl)cc1)C(=O)[C@H]1CCC[C@H]1NC(=O)Nc1ccccc1 |r| Show InChI InChI=1S/C26H32ClN3O3/c1-25(2)17-30(16-15-26(25,33)18-11-13-19(27)14-12-18)23(31)21-9-6-10-22(21)29-24(32)28-20-7-4-3-5-8-20/h3-5,7-8,11-14,21-22,33H,6,9-10,15-17H2,1-2H3,(H2,28,29,32)/t21-,22+,26-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 11.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| Assay Description
CCR1 ligand binding using scintillation proximity assay (SPA). |
US Patent US8536198 (2013)
BindingDB Entry DOI: 10.7270/Q2HT2MZ9 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 1
(Homo sapiens (Human)) | BDBM102314
(US8536198, 7)Show SMILES CC(C)(C)OC(=O)N[C@@H]1CCC[C@@H]1C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 |r| Show InChI InChI=1S/C24H35ClN2O4/c1-22(2,3)31-21(29)26-19-8-6-7-18(19)20(28)27-14-13-24(30,23(4,5)15-27)16-9-11-17(25)12-10-16/h9-12,18-19,30H,6-8,13-15H2,1-5H3,(H,26,29)/t18-,19+,24-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 12.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| Assay Description
CCR1 ligand binding using scintillation proximity assay (SPA). |
US Patent US8536198 (2013)
BindingDB Entry DOI: 10.7270/Q2HT2MZ9 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 1
(Homo sapiens (Human)) | BDBM102328
(US8536198, 83)Show SMILES CC1(C)CN(CC[C@]1(O)c1ccc(Cl)cc1)C(=O)[C@H]1CCC[C@H]1NC(=O)[C@@H]1CC[C@H](O)C1 |r| Show InChI InChI=1S/C25H35ClN2O4/c1-24(2)15-28(13-12-25(24,32)17-7-9-18(26)10-8-17)23(31)20-4-3-5-21(20)27-22(30)16-6-11-19(29)14-16/h7-10,16,19-21,29,32H,3-6,11-15H2,1-2H3,(H,27,30)/t16-,19+,20+,21-,25+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| Assay Description
CCR1 ligand binding using scintillation proximity assay (SPA). |
US Patent US8536198 (2013)
BindingDB Entry DOI: 10.7270/Q2HT2MZ9 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 1
(Homo sapiens (Human)) | BDBM102326
(US8536198, 76)Show SMILES C[C@@H](O)CNC(=O)N[C@@H]1CCCC[C@@H]1C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 |r| Show InChI InChI=1S/C24H36ClN3O4/c1-16(29)14-26-22(31)27-20-7-5-4-6-19(20)21(30)28-13-12-24(32,23(2,3)15-28)17-8-10-18(25)11-9-17/h8-11,16,19-20,29,32H,4-7,12-15H2,1-3H3,(H2,26,27,31)/t16-,19+,20-,24+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 14.6 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| Assay Description
CCR1 ligand binding using scintillation proximity assay (SPA). |
US Patent US8536198 (2013)
BindingDB Entry DOI: 10.7270/Q2HT2MZ9 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 1
(Homo sapiens (Human)) | BDBM102322
(US8536198, 60)Show SMILES CC1(C)CN(CC[C@]1(O)c1ccc(Cl)cc1)C(=O)[C@H]1CCCC[C@H]1NC(=O)CCc1ccccc1 |r| Show InChI InChI=1S/C29H37ClN2O3/c1-28(2)20-32(19-18-29(28,35)22-13-15-23(30)16-14-22)27(34)24-10-6-7-11-25(24)31-26(33)17-12-21-8-4-3-5-9-21/h3-5,8-9,13-16,24-25,35H,6-7,10-12,17-20H2,1-2H3,(H,31,33)/t24-,25+,29-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 15.7 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| Assay Description
CCR1 ligand binding using scintillation proximity assay (SPA). |
US Patent US8536198 (2013)
BindingDB Entry DOI: 10.7270/Q2HT2MZ9 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 1
(Homo sapiens (Human)) | BDBM102317
(US8536198, 11)Show SMILES CC1(C)CN(CC[C@]1(O)c1ccc(Cl)cc1)C(=O)[C@H]1CC(=O)CC[C@H]1NC(=O)c1ccccc1 |r| Show InChI InChI=1S/C27H31ClN2O4/c1-26(2)17-30(15-14-27(26,34)19-8-10-20(28)11-9-19)25(33)22-16-21(31)12-13-23(22)29-24(32)18-6-4-3-5-7-18/h3-11,22-23,34H,12-17H2,1-2H3,(H,29,32)/t22-,23+,27-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 17.2 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| Assay Description
CCR1 ligand binding using scintillation proximity assay (SPA). |
US Patent US8536198 (2013)
BindingDB Entry DOI: 10.7270/Q2HT2MZ9 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 1
(Homo sapiens (Human)) | BDBM102318
(US8536198, 35)Show SMILES CC1(C)CN(CC[C@]1(O)c1ccc(Cl)cc1)C(=O)[C@H]1CCCC[C@H]1NC(=O)Nc1ccccc1 |r| Show InChI InChI=1S/C27H34ClN3O3/c1-26(2)18-31(17-16-27(26,34)19-12-14-20(28)15-13-19)24(32)22-10-6-7-11-23(22)30-25(33)29-21-8-4-3-5-9-21/h3-5,8-9,12-15,22-23,34H,6-7,10-11,16-18H2,1-2H3,(H2,29,30,33)/t22-,23+,27-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 18.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| Assay Description
CCR1 ligand binding using scintillation proximity assay (SPA). |
US Patent US8536198 (2013)
BindingDB Entry DOI: 10.7270/Q2HT2MZ9 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 1
(Homo sapiens (Human)) | BDBM102320
(US8536198, 57)Show SMILES CC1(C)CN(CC[C@]1(O)c1ccc(Cl)cc1)C(=O)[C@H]1CCCC[C@H]1NC(=O)c1cncnc1 |r| Show InChI InChI=1S/C25H31ClN4O3/c1-24(2)15-30(12-11-25(24,33)18-7-9-19(26)10-8-18)23(32)20-5-3-4-6-21(20)29-22(31)17-13-27-16-28-14-17/h7-10,13-14,16,20-21,33H,3-6,11-12,15H2,1-2H3,(H,29,31)/t20-,21+,25-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 18.7 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| Assay Description
CCR1 ligand binding using scintillation proximity assay (SPA). |
US Patent US8536198 (2013)
BindingDB Entry DOI: 10.7270/Q2HT2MZ9 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 1
(Homo sapiens (Human)) | BDBM102325
(US8536198, 68)Show SMILES CC1(C)CN(CC[C@]1(O)c1ccc(Cl)cc1)C(=O)[C@H]1CCCC[C@H]1NC(=O)[C@@H](O)c1ccccc1 |r| Show InChI InChI=1S/C28H35ClN2O4/c1-27(2)18-31(17-16-28(27,35)20-12-14-21(29)15-13-20)26(34)22-10-6-7-11-23(22)30-25(33)24(32)19-8-4-3-5-9-19/h3-5,8-9,12-15,22-24,32,35H,6-7,10-11,16-18H2,1-2H3,(H,30,33)/t22-,23+,24-,28-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 581 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| Assay Description
CCR1 ligand binding using scintillation proximity assay (SPA). |
US Patent US8536198 (2013)
BindingDB Entry DOI: 10.7270/Q2HT2MZ9 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 1
(Homo sapiens (Human)) | BDBM102323
(US8536198, 61)Show SMILES CC1(C)CN(CC[C@]1(O)c1ccc(Cl)cc1)C(=O)[C@H]1CCCC[C@H]1NC(=O)CO |r| Show InChI InChI=1S/C22H31ClN2O4/c1-21(2)14-25(12-11-22(21,29)15-7-9-16(23)10-8-15)20(28)17-5-3-4-6-18(17)24-19(27)13-26/h7-10,17-18,26,29H,3-6,11-14H2,1-2H3,(H,24,27)/t17-,18+,22-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 768 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| Assay Description
CCR1 ligand binding using scintillation proximity assay (SPA). |
US Patent US8536198 (2013)
BindingDB Entry DOI: 10.7270/Q2HT2MZ9 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 1
(Homo sapiens (Human)) | BDBM102334
(US8536198, 104)Show SMILES CC1(C)CN(CC[C@]1(O)c1ccc(Cl)cc1)C(=O)[C@H]1CCCC[C@@]1(C)NC(=O)c1ccccc1 |r| Show InChI InChI=1S/C28H35ClN2O3/c1-26(2)19-31(18-17-28(26,34)21-12-14-22(29)15-13-21)25(33)23-11-7-8-16-27(23,3)30-24(32)20-9-5-4-6-10-20/h4-6,9-10,12-15,23,34H,7-8,11,16-19H2,1-3H3,(H,30,32)/t23-,27-,28+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 818 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| Assay Description
CCR1 ligand binding using scintillation proximity assay (SPA). |
US Patent US8536198 (2013)
BindingDB Entry DOI: 10.7270/Q2HT2MZ9 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 1
(Homo sapiens (Human)) | BDBM102324
(US8536198, 67)Show SMILES CC1(C)CN(CC[C@]1(O)c1ccc(Cl)cc1)C(=O)[C@H]1CCCC[C@H]1NC(=O)[C@H](O)c1ccccc1 |r| Show InChI InChI=1S/C28H35ClN2O4/c1-27(2)18-31(17-16-28(27,35)20-12-14-21(29)15-13-20)26(34)22-10-6-7-11-23(22)30-25(33)24(32)19-8-4-3-5-9-19/h3-5,8-9,12-15,22-24,32,35H,6-7,10-11,16-18H2,1-2H3,(H,30,33)/t22-,23+,24+,28-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 858 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| Assay Description
CCR1 ligand binding using scintillation proximity assay (SPA). |
US Patent US8536198 (2013)
BindingDB Entry DOI: 10.7270/Q2HT2MZ9 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 1
(Homo sapiens (Human)) | BDBM102321
(US8536198, 58)Show SMILES CC1(C)CN(CC[C@]1(O)c1ccc(Cl)cc1)C(=O)[C@H]1CCCC[C@H]1NC(=O)CCN1CCCCC1 |r| Show InChI InChI=1S/C28H42ClN3O3/c1-27(2)20-32(19-15-28(27,35)21-10-12-22(29)13-11-21)26(34)23-8-4-5-9-24(23)30-25(33)14-18-31-16-6-3-7-17-31/h10-13,23-24,35H,3-9,14-20H2,1-2H3,(H,30,33)/t23-,24+,28-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 932 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| Assay Description
CCR1 ligand binding using scintillation proximity assay (SPA). |
US Patent US8536198 (2013)
BindingDB Entry DOI: 10.7270/Q2HT2MZ9 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 1
(Homo sapiens (Human)) | BDBM102319
(US8536198, 41)Show SMILES COC(=O)N[C@@H]1CCCC[C@@H]1C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 |r| Show InChI InChI=1S/C22H31ClN2O4/c1-21(2)14-25(13-12-22(21,28)15-8-10-16(23)11-9-15)19(26)17-6-4-5-7-18(17)24-20(27)29-3/h8-11,17-18,28H,4-7,12-14H2,1-3H3,(H,24,27)/t17-,18+,22-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 997 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| Assay Description
CCR1 ligand binding using scintillation proximity assay (SPA). |
US Patent US8536198 (2013)
BindingDB Entry DOI: 10.7270/Q2HT2MZ9 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 1
(Homo sapiens (Human)) | BDBM102316
(US8536198, 10)Show SMILES CC1(C)CN(CC[C@]1(O)c1ccc(Cl)cc1)C(=O)[C@H]1CC2(CC[C@H]1NC(=O)c1ccccc1)OCCO2 |r| Show InChI InChI=1S/C29H35ClN2O5/c1-27(2)19-32(15-14-29(27,35)21-8-10-22(30)11-9-21)26(34)23-18-28(36-16-17-37-28)13-12-24(23)31-25(33)20-6-4-3-5-7-20/h3-11,23-24,35H,12-19H2,1-2H3,(H,31,33)/t23-,24+,29-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 1.07E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| Assay Description
CCR1 ligand binding using scintillation proximity assay (SPA). |
US Patent US8536198 (2013)
BindingDB Entry DOI: 10.7270/Q2HT2MZ9 |
More data for this
Ligand-Target Pair | |
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