Affinity Data by Patent

Patent code US8551963

Found 10 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM103623 (US8551963, 1a) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Corporation US Patent					Assay Description Competition binding assay used herein were developed validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.				US Patent US8551963 (2013) BindingDB Entry DOI: 10.7270/Q23F4N7J
Ambit Biosciences Corporation US Patent					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM103622 (US8551963, I-1) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Corporation US Patent					Assay Description Competition binding assay used herein were developed validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.				US Patent US8551963 (2013) BindingDB Entry DOI: 10.7270/Q23F4N7J
Ambit Biosciences Corporation US Patent					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM103622 (US8551963, I-1) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	0.770	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Corporation US Patent					Assay Description Competition binding assay used herein were developed validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.				US Patent US8551963 (2013) BindingDB Entry DOI: 10.7270/Q23F4N7J
Ambit Biosciences Corporation US Patent					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM103622 (US8551963, I-1) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Corporation US Patent					Assay Description Competition binding assay used herein were developed validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.				US Patent US8551963 (2013) BindingDB Entry DOI: 10.7270/Q23F4N7J
Ambit Biosciences Corporation US Patent					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM103622 (US8551963, I-1) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	0.680	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Corporation US Patent					Assay Description Competition binding assay used herein were developed validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.				US Patent US8551963 (2013) BindingDB Entry DOI: 10.7270/Q23F4N7J
Ambit Biosciences Corporation US Patent					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM103623 (US8551963, 1a) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Corporation US Patent					Assay Description Competition binding assay used herein were developed validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.				US Patent US8551963 (2013) BindingDB Entry DOI: 10.7270/Q23F4N7J
Ambit Biosciences Corporation US Patent					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM103623 (US8551963, 1a) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	7.10	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Corporation US Patent					Assay Description Competition binding assay used herein were developed validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.				US Patent US8551963 (2013) BindingDB Entry DOI: 10.7270/Q23F4N7J
Ambit Biosciences Corporation US Patent					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM103623 (US8551963, 1a) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Corporation US Patent					Assay Description Competition binding assay used herein were developed validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.				US Patent US8551963 (2013) BindingDB Entry DOI: 10.7270/Q23F4N7J
Ambit Biosciences Corporation US Patent					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM103623 (US8551963, 1a) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Corporation US Patent					Assay Description Competition binding assay used herein were developed validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.				US Patent US8551963 (2013) BindingDB Entry DOI: 10.7270/Q23F4N7J
Ambit Biosciences Corporation US Patent					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM103622 (US8551963, I-1) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	0.690	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Corporation US Patent					Assay Description Competition binding assay used herein were developed validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336.				US Patent US8551963 (2013) BindingDB Entry DOI: 10.7270/Q23F4N7J
Ambit Biosciences Corporation US Patent					More data for this Ligand-Target Pair

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* indicates data uncertainty>20%