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Patent code US8552033

Compile Data Set for Download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-X-C chemokine receptor type 2


(Homo sapiens (Human))		BDBM103368
PNG
(US8552033, 10)
Show SMILES CCC(NC(=O)c1ccc2ccccc2c1OCc1ccc(cc1)C(F)(F)F)(C(O)=O)c1ccccc1
Show InChI InChI=1S/C29H24F3NO4/c1-2-28(27(35)36,21-9-4-3-5-10-21)33-26(34)24-17-14-20-8-6-7-11-23(20)25(24)37-18-19-12-15-22(16-13-19)29(30,31)32/h3-17H,2,18H2,1H3,(H,33,34)(H,35,36)
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UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem
US Patent
n/an/a 2.20E+3n/an/an/an/an/an/a



SANOFI

US Patent


Assay Description
The assay is based on the detection of intracellular calcium changes detected by the selective, calcium-chelating dye, Fluo-4 (Molecular Probes).

US Patent US8552033 (2013)


BindingDB Entry DOI: 10.7270/Q2NC5ZTJ
More data for this
Ligand-Target Pair
C-X-C chemokine receptor type 2


(Homo sapiens (Human))		BDBM103369
PNG
(US8552033, 12)
Show SMILES OC(=O)C1(CCOCC1)NC(=O)c1cc(F)c2ccccc2c1OCc1ccc(SC(F)(F)F)cc1
Show InChI InChI=1S/C25H21F4NO5S/c26-20-13-19(22(31)30-24(23(32)33)9-11-34-12-10-24)21(18-4-2-1-3-17(18)20)35-14-15-5-7-16(8-6-15)36-25(27,28)29/h1-8,13H,9-12,14H2,(H,30,31)(H,32,33)
PDB

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UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 6.00E+3n/an/an/an/an/an/a



SANOFI

US Patent


Assay Description
The assay is based on the detection of intracellular calcium changes detected by the selective, calcium-chelating dye, Fluo-4 (Molecular Probes).

US Patent US8552033 (2013)


BindingDB Entry DOI: 10.7270/Q2NC5ZTJ
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%