Found 16 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Tyrosine-protein kinase ABL1
(Homo sapiens (Human)) | BDBM104260
(US8580815, ND-0020)Show InChI InChI=1S/C16H12BrN3O3/c1-23-16(22)13-7-9-6-10(8-18-14(9)20-13)19-15(21)11-4-2-3-5-12(11)17/h2-8H,1H3,(H,18,20)(H,19,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
Oribase Pharma
US Patent
| Assay Description
In vitro kinase assay. |
US Patent US8580815 (2013)
BindingDB Entry DOI: 10.7270/Q2GH9GKZ |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase ABL1
(Homo sapiens (Human)) | BDBM104260
(US8580815, ND-0020)Show InChI InChI=1S/C16H12BrN3O3/c1-23-16(22)13-7-9-6-10(8-18-14(9)20-13)19-15(21)11-4-2-3-5-12(11)17/h2-8H,1H3,(H,18,20)(H,19,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
Oribase Pharma
US Patent
| Assay Description
In vitro kinase assay. |
US Patent US8580815 (2013)
BindingDB Entry DOI: 10.7270/Q2GH9GKZ |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase ABL1
(Homo sapiens (Human)) | BDBM104261
(US8580815, ND-0047)Show SMILES COC(=O)c1cc2cc(NC(=O)c3c(F)cccc3OC)cnc2[nH]1 Show InChI InChI=1S/C17H14FN3O4/c1-24-13-5-3-4-11(18)14(13)16(22)20-10-6-9-7-12(17(23)25-2)21-15(9)19-8-10/h3-8H,1-2H3,(H,19,21)(H,20,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 18.3 | n/a | n/a | n/a | n/a | n/a | n/a |
Oribase Pharma
US Patent
| Assay Description
In vitro kinase assay. |
US Patent US8580815 (2013)
BindingDB Entry DOI: 10.7270/Q2GH9GKZ |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase ABL1
(Homo sapiens (Human)) | BDBM104261
(US8580815, ND-0047)Show SMILES COC(=O)c1cc2cc(NC(=O)c3c(F)cccc3OC)cnc2[nH]1 Show InChI InChI=1S/C17H14FN3O4/c1-24-13-5-3-4-11(18)14(13)16(22)20-10-6-9-7-12(17(23)25-2)21-15(9)19-8-10/h3-8H,1-2H3,(H,19,21)(H,20,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 18.4 | n/a | n/a | n/a | n/a | n/a | n/a |
Oribase Pharma
US Patent
| Assay Description
In vitro kinase assay. |
US Patent US8580815 (2013)
BindingDB Entry DOI: 10.7270/Q2GH9GKZ |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase ABL1
(Homo sapiens (Human)) | BDBM104263
(US8580815, ND-0009)Show SMILES CN(C)CCCNC(=O)c1cc2cc(NC(=O)c3ccccc3Br)cnc2[nH]1 Show InChI InChI=1S/C20H22BrN5O2/c1-26(2)9-5-8-22-20(28)17-11-13-10-14(12-23-18(13)25-17)24-19(27)15-6-3-4-7-16(15)21/h3-4,6-7,10-12H,5,8-9H2,1-2H3,(H,22,28)(H,23,25)(H,24,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 21.8 | n/a | n/a | n/a | n/a | n/a | n/a |
Oribase Pharma
US Patent
| Assay Description
In vitro kinase assay. |
US Patent US8580815 (2013)
BindingDB Entry DOI: 10.7270/Q2GH9GKZ |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase ABL1
(Homo sapiens (Human)) | BDBM104263
(US8580815, ND-0009)Show SMILES CN(C)CCCNC(=O)c1cc2cc(NC(=O)c3ccccc3Br)cnc2[nH]1 Show InChI InChI=1S/C20H22BrN5O2/c1-26(2)9-5-8-22-20(28)17-11-13-10-14(12-23-18(13)25-17)24-19(27)15-6-3-4-7-16(15)21/h3-4,6-7,10-12H,5,8-9H2,1-2H3,(H,22,28)(H,23,25)(H,24,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 28.0 | n/a | n/a | n/a | n/a | n/a | n/a |
Oribase Pharma
US Patent
| Assay Description
In vitro kinase assay. |
US Patent US8580815 (2013)
BindingDB Entry DOI: 10.7270/Q2GH9GKZ |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase ABL1
(Homo sapiens (Human)) | BDBM104260
(US8580815, ND-0020)Show InChI InChI=1S/C16H12BrN3O3/c1-23-16(22)13-7-9-6-10(8-18-14(9)20-13)19-15(21)11-4-2-3-5-12(11)17/h2-8H,1H3,(H,18,20)(H,19,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 44.6 | n/a | n/a | n/a | n/a | n/a | n/a |
Oribase Pharma
US Patent
| Assay Description
In vitro kinase assay. |
US Patent US8580815 (2013)
BindingDB Entry DOI: 10.7270/Q2GH9GKZ |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase ABL1
(Homo sapiens (Human)) | BDBM104262
(US8580815, ND-0037)Show SMILES Brc1ccccc1C(=O)Nc1cnc2[nH]c(Cc3ccc[nH]3)cc2c1 Show InChI InChI=1S/C19H15BrN4O/c20-17-6-2-1-5-16(17)19(25)24-15-9-12-8-14(23-18(12)22-11-15)10-13-4-3-7-21-13/h1-9,11,21H,10H2,(H,22,23)(H,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 68.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Oribase Pharma
US Patent
| Assay Description
In vitro kinase assay. |
US Patent US8580815 (2013)
BindingDB Entry DOI: 10.7270/Q2GH9GKZ |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase ABL1
(Homo sapiens (Human)) | BDBM104262
(US8580815, ND-0037)Show SMILES Brc1ccccc1C(=O)Nc1cnc2[nH]c(Cc3ccc[nH]3)cc2c1 Show InChI InChI=1S/C19H15BrN4O/c20-17-6-2-1-5-16(17)19(25)24-15-9-12-8-14(23-18(12)22-11-15)10-13-4-3-7-21-13/h1-9,11,21H,10H2,(H,22,23)(H,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 85.0 | n/a | n/a | n/a | n/a | n/a | n/a |
Oribase Pharma
US Patent
| Assay Description
In vitro kinase assay. |
US Patent US8580815 (2013)
BindingDB Entry DOI: 10.7270/Q2GH9GKZ |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase ABL1
(Homo sapiens (Human)) | BDBM104261
(US8580815, ND-0047)Show SMILES COC(=O)c1cc2cc(NC(=O)c3c(F)cccc3OC)cnc2[nH]1 Show InChI InChI=1S/C17H14FN3O4/c1-24-13-5-3-4-11(18)14(13)16(22)20-10-6-9-7-12(17(23)25-2)21-15(9)19-8-10/h3-8H,1-2H3,(H,19,21)(H,20,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 382 | n/a | n/a | n/a | n/a | n/a | n/a |
Oribase Pharma
US Patent
| Assay Description
In vitro kinase assay. |
US Patent US8580815 (2013)
BindingDB Entry DOI: 10.7270/Q2GH9GKZ |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase ABL1
(Homo sapiens (Human)) | BDBM104262
(US8580815, ND-0037)Show SMILES Brc1ccccc1C(=O)Nc1cnc2[nH]c(Cc3ccc[nH]3)cc2c1 Show InChI InChI=1S/C19H15BrN4O/c20-17-6-2-1-5-16(17)19(25)24-15-9-12-8-14(23-18(12)22-11-15)10-13-4-3-7-21-13/h1-9,11,21H,10H2,(H,22,23)(H,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 655 | n/a | n/a | n/a | n/a | n/a | n/a |
Oribase Pharma
US Patent
| Assay Description
In vitro kinase assay. |
US Patent US8580815 (2013)
BindingDB Entry DOI: 10.7270/Q2GH9GKZ |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase ABL1
(Homo sapiens (Human)) | BDBM104263
(US8580815, ND-0009)Show SMILES CN(C)CCCNC(=O)c1cc2cc(NC(=O)c3ccccc3Br)cnc2[nH]1 Show InChI InChI=1S/C20H22BrN5O2/c1-26(2)9-5-8-22-20(28)17-11-13-10-14(12-23-18(13)25-17)24-19(27)15-6-3-4-7-16(15)21/h3-4,6-7,10-12H,5,8-9H2,1-2H3,(H,22,28)(H,23,25)(H,24,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 709 | n/a | n/a | n/a | n/a | n/a | n/a |
Oribase Pharma
US Patent
| Assay Description
In vitro kinase assay. |
US Patent US8580815 (2013)
BindingDB Entry DOI: 10.7270/Q2GH9GKZ |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase ABL1
(Homo sapiens (Human)) | BDBM104262
(US8580815, ND-0037)Show SMILES Brc1ccccc1C(=O)Nc1cnc2[nH]c(Cc3ccc[nH]3)cc2c1 Show InChI InChI=1S/C19H15BrN4O/c20-17-6-2-1-5-16(17)19(25)24-15-9-12-8-14(23-18(12)22-11-15)10-13-4-3-7-21-13/h1-9,11,21H,10H2,(H,22,23)(H,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 6.33E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Oribase Pharma
US Patent
| Assay Description
In vitro kinase assay. |
US Patent US8580815 (2013)
BindingDB Entry DOI: 10.7270/Q2GH9GKZ |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase ABL1
(Homo sapiens (Human)) | BDBM104263
(US8580815, ND-0009)Show SMILES CN(C)CCCNC(=O)c1cc2cc(NC(=O)c3ccccc3Br)cnc2[nH]1 Show InChI InChI=1S/C20H22BrN5O2/c1-26(2)9-5-8-22-20(28)17-11-13-10-14(12-23-18(13)25-17)24-19(27)15-6-3-4-7-16(15)21/h3-4,6-7,10-12H,5,8-9H2,1-2H3,(H,22,28)(H,23,25)(H,24,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Oribase Pharma
US Patent
| Assay Description
In vitro kinase assay. |
US Patent US8580815 (2013)
BindingDB Entry DOI: 10.7270/Q2GH9GKZ |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase ABL1
(Homo sapiens (Human)) | BDBM104261
(US8580815, ND-0047)Show SMILES COC(=O)c1cc2cc(NC(=O)c3c(F)cccc3OC)cnc2[nH]1 Show InChI InChI=1S/C17H14FN3O4/c1-24-13-5-3-4-11(18)14(13)16(22)20-10-6-9-7-12(17(23)25-2)21-15(9)19-8-10/h3-8H,1-2H3,(H,19,21)(H,20,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Oribase Pharma
US Patent
| Assay Description
In vitro kinase assay. |
US Patent US8580815 (2013)
BindingDB Entry DOI: 10.7270/Q2GH9GKZ |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase ABL1
(Homo sapiens (Human)) | BDBM104260
(US8580815, ND-0020)Show InChI InChI=1S/C16H12BrN3O3/c1-23-16(22)13-7-9-6-10(8-18-14(9)20-13)19-15(21)11-4-2-3-5-12(11)17/h2-8H,1H3,(H,18,20)(H,19,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Oribase Pharma
US Patent
| Assay Description
In vitro kinase assay. |
US Patent US8580815 (2013)
BindingDB Entry DOI: 10.7270/Q2GH9GKZ |
More data for this
Ligand-Target Pair | |
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