Found 144 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM67818
(2-chloranyl-N-(3-quinoxalin-2-ylphenyl)ethanamide ...)Show InChI InChI=1S/C16H12ClN3O/c17-9-16(21)19-12-5-3-4-11(8-12)15-10-18-13-6-1-2-7-14(13)20-15/h1-8,10H,9H2,(H,19,21) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM107139
(US8592415, 24)Show InChI InChI=1S/C16H12BrN3O/c17-9-16(21)19-12-5-3-4-11(8-12)15-10-18-13-6-1-2-7-14(13)20-15/h1-8,10H,9H2,(H,19,21) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM107142
(US8592415, 27)Show SMILES CS(=O)(=O)OCC(=O)Nc1cccc(c1)-c1cnc2ccccc2n1 Show InChI InChI=1S/C17H15N3O4S/c1-25(22,23)24-11-17(21)19-13-6-4-5-12(9-13)16-10-18-14-7-2-3-8-15(14)20-16/h2-10H,11H2,1H3,(H,19,21) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM107137
(US8592415, 22)Show InChI InChI=1S/C17H13N3O/c1-2-17(21)19-13-7-5-6-12(10-13)16-11-18-14-8-3-4-9-15(14)20-16/h2-11H,1H2,(H,19,21) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM107124
(US8592415, 8)Show InChI InChI=1S/C17H12N4O/c18-9-8-17(22)20-13-5-3-4-12(10-13)16-11-19-14-6-1-2-7-15(14)21-16/h1-7,10-11H,8H2,(H,20,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 136 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM107125
(US8592415, 9)Show InChI InChI=1S/C21H22N4O/c26-21(15-25-11-4-1-5-12-25)23-17-8-6-7-16(13-17)20-14-22-18-9-2-3-10-19(18)24-20/h2-3,6-10,13-14H,1,4-5,11-12,15H2,(H,23,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 175 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM107131
(US8592415, 16)Show SMILES O=C(CN1CCN(CC1)c1ccccc1)Nc1cccc(c1)-c1cnc2ccccc2n1 Show InChI InChI=1S/C26H25N5O/c32-26(19-30-13-15-31(16-14-30)22-9-2-1-3-10-22)28-21-8-6-7-20(17-21)25-18-27-23-11-4-5-12-24(23)29-25/h1-12,17-18H,13-16,19H2,(H,28,32) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM107136
(US8592415, 21)Show InChI InChI=1S/C17H14ClN3O/c1-11(18)17(22)20-13-6-4-5-12(9-13)16-10-19-14-7-2-3-8-15(14)21-16/h2-11H,1H3,(H,20,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM107133
(US8592415, 18)Show InChI InChI=1S/C16H11Cl2N3O/c17-15(18)16(22)20-11-5-3-4-10(8-11)14-9-19-12-6-1-2-7-13(12)21-14/h1-9,15H,(H,20,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM107120
(US8592415, 4)Show SMILES Clc1ccc(cc1)N1CCN(CC(=O)Nc2cccc(c2)-c2cnc3ccccc3n2)CC1 Show InChI InChI=1S/C26H24ClN5O/c27-20-8-10-22(11-9-20)32-14-12-31(13-15-32)18-26(33)29-21-5-3-4-19(16-21)25-17-28-23-6-1-2-7-24(23)30-25/h1-11,16-17H,12-15,18H2,(H,29,33) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM107142
(US8592415, 27)Show SMILES CS(=O)(=O)OCC(=O)Nc1cccc(c1)-c1cnc2ccccc2n1 Show InChI InChI=1S/C17H15N3O4S/c1-25(22,23)24-11-17(21)19-13-6-4-5-12(9-13)16-10-18-14-7-2-3-8-15(14)20-16/h2-10H,11H2,1H3,(H,19,21) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM107151
(US8592415, 36)Show SMILES NS(=O)(=O)CCC(=O)Nc1cccc(c1)-c1cnc2ccccc2n1 Show InChI InChI=1S/C17H16N4O3S/c18-25(23,24)9-8-17(22)20-13-5-3-4-12(10-13)16-11-19-14-6-1-2-7-15(14)21-16/h1-7,10-11H,8-9H2,(H,20,22)(H2,18,23,24) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM107137
(US8592415, 22)Show InChI InChI=1S/C17H13N3O/c1-2-17(21)19-13-7-5-6-12(10-13)16-11-18-14-8-3-4-9-15(14)20-16/h2-11H,1H2,(H,19,21) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM107151
(US8592415, 36)Show SMILES NS(=O)(=O)CCC(=O)Nc1cccc(c1)-c1cnc2ccccc2n1 Show InChI InChI=1S/C17H16N4O3S/c18-25(23,24)9-8-17(22)20-13-5-3-4-12(10-13)16-11-19-14-6-1-2-7-15(14)21-16/h1-7,10-11H,8-9H2,(H,20,22)(H2,18,23,24) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human)) | BDBM107137
(US8592415, 22)Show InChI InChI=1S/C17H13N3O/c1-2-17(21)19-13-7-5-6-12(10-13)16-11-18-14-8-3-4-9-15(14)20-16/h2-11H,1H2,(H,19,21) | PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human)) | BDBM107149
(US8592415, 34)Show SMILES OC1CCN(CC(=O)Nc2cccc(c2)-c2cnc3ccccc3n2)CC1 Show InChI InChI=1S/C21H22N4O2/c26-17-8-10-25(11-9-17)14-21(27)23-16-5-3-4-15(12-16)20-13-22-18-6-1-2-7-19(18)24-20/h1-7,12-13,17,26H,8-11,14H2,(H,23,27) | PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM107141
(US8592415, 26)Show SMILES FC(F)(F)C(=O)CC(=O)Nc1cccc(c1)-c1cnc2ccccc2n1 Show InChI InChI=1S/C18H12F3N3O2/c19-18(20,21)16(25)9-17(26)23-12-5-3-4-11(8-12)15-10-22-13-6-1-2-7-14(13)24-15/h1-8,10H,9H2,(H,23,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM107133
(US8592415, 18)Show InChI InChI=1S/C16H11Cl2N3O/c17-15(18)16(22)20-11-5-3-4-10(8-11)14-9-19-12-6-1-2-7-13(12)21-14/h1-9,15H,(H,20,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM107143
(US8592415, 28)Show InChI InChI=1S/C18H15N3O3/c1-12(22)24-11-18(23)20-14-6-4-5-13(9-14)17-10-19-15-7-2-3-8-16(15)21-17/h2-10H,11H2,1H3,(H,20,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM107139
(US8592415, 24)Show InChI InChI=1S/C16H12BrN3O/c17-9-16(21)19-12-5-3-4-11(8-12)15-10-18-13-6-1-2-7-14(13)20-15/h1-8,10H,9H2,(H,19,21) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM107144
(US8592415, 29)Show InChI InChI=1S/C16H13N3O2/c20-10-16(21)18-12-5-3-4-11(8-12)15-9-17-13-6-1-2-7-14(13)19-15/h1-9,20H,10H2,(H,18,21) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM107147
(US8592415, 32)Show InChI InChI=1S/C19H17N3O3/c1-2-25-19(24)11-18(23)21-14-7-5-6-13(10-14)17-12-20-15-8-3-4-9-16(15)22-17/h3-10,12H,2,11H2,1H3,(H,21,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human)) | BDBM107133
(US8592415, 18)Show InChI InChI=1S/C16H11Cl2N3O/c17-15(18)16(22)20-11-5-3-4-10(8-11)14-9-19-12-6-1-2-7-13(12)21-14/h1-9,15H,(H,20,22) | PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human)) | BDBM107143
(US8592415, 28)Show InChI InChI=1S/C18H15N3O3/c1-12(22)24-11-18(23)20-14-6-4-5-13(9-14)17-10-19-15-7-2-3-8-16(15)21-17/h2-10H,11H2,1H3,(H,20,23) | PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM107145
(US8592415, 30)Show InChI InChI=1S/C18H15N3O2S/c1-12(22)24-11-18(23)20-14-6-4-5-13(9-14)17-10-19-15-7-2-3-8-16(15)21-17/h2-10H,11H2,1H3,(H,20,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM107146
(US8592415, 31)Show SMILES CC(Nc1cccc(c1)-c1cnc2ccccc2n1)=C1CCOC1=O |w:1.0| Show InChI InChI=1S/C20H17N3O2/c1-13(16-9-10-25-20(16)24)22-15-6-4-5-14(11-15)19-12-21-17-7-2-3-8-18(17)23-19/h2-8,11-12,22H,9-10H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM107138
(US8592415, 23)Show InChI InChI=1S/C18H15N3O/c1-2-6-18(22)20-14-8-5-7-13(11-14)17-12-19-15-9-3-4-10-16(15)21-17/h2-5,7-12H,1,6H2,(H,20,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM107140
(US8592415, 25)Show InChI InChI=1S/C17H15N3OS/c1-22-11-17(21)19-13-6-4-5-12(9-13)16-10-18-14-7-2-3-8-15(14)20-16/h2-10H,11H2,1H3,(H,19,21) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM107141
(US8592415, 26)Show SMILES FC(F)(F)C(=O)CC(=O)Nc1cccc(c1)-c1cnc2ccccc2n1 Show InChI InChI=1S/C18H12F3N3O2/c19-18(20,21)16(25)9-17(26)23-12-5-3-4-11(8-12)15-10-22-13-6-1-2-7-14(13)24-15/h1-8,10H,9H2,(H,23,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM107144
(US8592415, 29)Show InChI InChI=1S/C16H13N3O2/c20-10-16(21)18-12-5-3-4-11(8-12)15-9-17-13-6-1-2-7-14(13)19-15/h1-9,20H,10H2,(H,18,21) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM107147
(US8592415, 32)Show InChI InChI=1S/C19H17N3O3/c1-2-25-19(24)11-18(23)21-14-7-5-6-13(10-14)17-12-20-15-8-3-4-9-16(15)22-17/h3-10,12H,2,11H2,1H3,(H,21,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human)) | BDBM107140
(US8592415, 25)Show InChI InChI=1S/C17H15N3OS/c1-22-11-17(21)19-13-6-4-5-12(9-13)16-10-18-14-7-2-3-8-15(14)20-16/h2-10H,11H2,1H3,(H,19,21) | PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM107151
(US8592415, 36)Show SMILES NS(=O)(=O)CCC(=O)Nc1cccc(c1)-c1cnc2ccccc2n1 Show InChI InChI=1S/C17H16N4O3S/c18-25(23,24)9-8-17(22)20-13-5-3-4-12(10-13)16-11-19-14-6-1-2-7-15(14)21-16/h1-7,10-11H,8-9H2,(H,20,22)(H2,18,23,24) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM107145
(US8592415, 30)Show InChI InChI=1S/C18H15N3O2S/c1-12(22)24-11-18(23)20-14-6-4-5-13(9-14)17-10-19-15-7-2-3-8-16(15)21-17/h2-10H,11H2,1H3,(H,20,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM107146
(US8592415, 31)Show SMILES CC(Nc1cccc(c1)-c1cnc2ccccc2n1)=C1CCOC1=O |w:1.0| Show InChI InChI=1S/C20H17N3O2/c1-13(16-9-10-25-20(16)24)22-15-6-4-5-14(11-15)19-12-21-17-7-2-3-8-18(17)23-19/h2-8,11-12,22H,9-10H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM107149
(US8592415, 34)Show SMILES OC1CCN(CC(=O)Nc2cccc(c2)-c2cnc3ccccc3n2)CC1 Show InChI InChI=1S/C21H22N4O2/c26-17-8-10-25(11-9-17)14-21(27)23-16-5-3-4-15(12-16)20-13-22-18-6-1-2-7-19(18)24-20/h1-7,12-13,17,26H,8-11,14H2,(H,23,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM107138
(US8592415, 23)Show InChI InChI=1S/C18H15N3O/c1-2-6-18(22)20-14-8-5-7-13(11-14)17-12-19-15-9-3-4-10-16(15)21-17/h2-5,7-12H,1,6H2,(H,20,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM107142
(US8592415, 27)Show SMILES CS(=O)(=O)OCC(=O)Nc1cccc(c1)-c1cnc2ccccc2n1 Show InChI InChI=1S/C17H15N3O4S/c1-25(22,23)24-11-17(21)19-13-6-4-5-12(9-13)16-10-18-14-7-2-3-8-15(14)20-16/h2-10H,11H2,1H3,(H,19,21) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM107143
(US8592415, 28)Show InChI InChI=1S/C18H15N3O3/c1-12(22)24-11-18(23)20-14-6-4-5-13(9-14)17-10-19-15-7-2-3-8-16(15)21-17/h2-10H,11H2,1H3,(H,20,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM107149
(US8592415, 34)Show SMILES OC1CCN(CC(=O)Nc2cccc(c2)-c2cnc3ccccc3n2)CC1 Show InChI InChI=1S/C21H22N4O2/c26-17-8-10-25(11-9-17)14-21(27)23-16-5-3-4-15(12-16)20-13-22-18-6-1-2-7-19(18)24-20/h1-7,12-13,17,26H,8-11,14H2,(H,23,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human)) | BDBM107138
(US8592415, 23)Show InChI InChI=1S/C18H15N3O/c1-2-6-18(22)20-14-8-5-7-13(11-14)17-12-19-15-9-3-4-10-16(15)21-17/h2-5,7-12H,1,6H2,(H,20,22) | PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human)) | BDBM107142
(US8592415, 27)Show SMILES CS(=O)(=O)OCC(=O)Nc1cccc(c1)-c1cnc2ccccc2n1 Show InChI InChI=1S/C17H15N3O4S/c1-25(22,23)24-11-17(21)19-13-6-4-5-12(9-13)16-10-18-14-7-2-3-8-15(14)20-16/h2-10H,11H2,1H3,(H,19,21) | PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human)) | BDBM107144
(US8592415, 29)Show InChI InChI=1S/C16H13N3O2/c20-10-16(21)18-12-5-3-4-11(8-12)15-9-17-13-6-1-2-7-14(13)19-15/h1-9,20H,10H2,(H,18,21) | PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human)) | BDBM107147
(US8592415, 32)Show InChI InChI=1S/C19H17N3O3/c1-2-25-19(24)11-18(23)21-14-7-5-6-13(10-14)17-12-20-15-8-3-4-9-16(15)22-17/h3-10,12H,2,11H2,1H3,(H,21,23) | PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM107144
(US8592415, 29)Show InChI InChI=1S/C16H13N3O2/c20-10-16(21)18-12-5-3-4-11(8-12)15-9-17-13-6-1-2-7-14(13)19-15/h1-9,20H,10H2,(H,18,21) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM107147
(US8592415, 32)Show InChI InChI=1S/C19H17N3O3/c1-2-25-19(24)11-18(23)21-14-7-5-6-13(10-14)17-12-20-15-8-3-4-9-16(15)22-17/h3-10,12H,2,11H2,1H3,(H,21,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM107137
(US8592415, 22)Show InChI InChI=1S/C17H13N3O/c1-2-17(21)19-13-7-5-6-12(10-13)16-11-18-14-8-3-4-9-15(14)20-16/h2-11H,1H2,(H,19,21) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM107139
(US8592415, 24)Show InChI InChI=1S/C16H12BrN3O/c17-9-16(21)19-12-5-3-4-11(8-12)15-10-18-13-6-1-2-7-14(13)20-15/h1-8,10H,9H2,(H,19,21) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human)) | BDBM107148
(US8592415, 33)Show SMILES O=C(CN1CCN(CC1)c1ccncc1)Nc1cccc(c1)-c1cnc2ccccc2n1 Show InChI InChI=1S/C25H24N6O/c32-25(18-30-12-14-31(15-13-30)21-8-10-26-11-9-21)28-20-5-3-4-19(16-20)24-17-27-22-6-1-2-7-23(22)29-24/h1-11,16-17H,12-15,18H2,(H,28,32) | PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM107138
(US8592415, 23)Show InChI InChI=1S/C18H15N3O/c1-2-6-18(22)20-14-8-5-7-13(11-14)17-12-19-15-9-3-4-10-16(15)21-17/h2-5,7-12H,1,6H2,(H,20,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM107149
(US8592415, 34)Show SMILES OC1CCN(CC(=O)Nc2cccc(c2)-c2cnc3ccccc3n2)CC1 Show InChI InChI=1S/C21H22N4O2/c26-17-8-10-25(11-9-17)14-21(27)23-16-5-3-4-15(12-16)20-13-22-18-6-1-2-7-19(18)24-20/h1-7,12-13,17,26H,8-11,14H2,(H,23,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM107148
(US8592415, 33)Show SMILES O=C(CN1CCN(CC1)c1ccncc1)Nc1cccc(c1)-c1cnc2ccccc2n1 Show InChI InChI=1S/C25H24N6O/c32-25(18-30-12-14-31(15-13-30)21-8-10-26-11-9-21)28-20-5-3-4-19(16-20)24-17-27-22-6-1-2-7-23(22)29-24/h1-11,16-17H,12-15,18H2,(H,28,32) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM107141
(US8592415, 26)Show SMILES FC(F)(F)C(=O)CC(=O)Nc1cccc(c1)-c1cnc2ccccc2n1 Show InChI InChI=1S/C18H12F3N3O2/c19-18(20,21)16(25)9-17(26)23-12-5-3-4-11(8-12)15-10-22-13-6-1-2-7-14(13)24-15/h1-8,10H,9H2,(H,23,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM107145
(US8592415, 30)Show InChI InChI=1S/C18H15N3O2S/c1-12(22)24-11-18(23)20-14-6-4-5-13(9-14)17-10-19-15-7-2-3-8-16(15)21-17/h2-10H,11H2,1H3,(H,20,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM107148
(US8592415, 33)Show SMILES O=C(CN1CCN(CC1)c1ccncc1)Nc1cccc(c1)-c1cnc2ccccc2n1 Show InChI InChI=1S/C25H24N6O/c32-25(18-30-12-14-31(15-13-30)21-8-10-26-11-9-21)28-20-5-3-4-19(16-20)24-17-27-22-6-1-2-7-23(22)29-24/h1-11,16-17H,12-15,18H2,(H,28,32) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM107133
(US8592415, 18)Show InChI InChI=1S/C16H11Cl2N3O/c17-15(18)16(22)20-11-5-3-4-10(8-11)14-9-19-12-6-1-2-7-13(12)21-14/h1-9,15H,(H,20,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM107146
(US8592415, 31)Show SMILES CC(Nc1cccc(c1)-c1cnc2ccccc2n1)=C1CCOC1=O |w:1.0| Show InChI InChI=1S/C20H17N3O2/c1-13(16-9-10-25-20(16)24)22-15-6-4-5-14(11-15)19-12-21-17-7-2-3-8-18(17)23-19/h2-8,11-12,22H,9-10H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human)) | BDBM107139
(US8592415, 24)Show InChI InChI=1S/C16H12BrN3O/c17-9-16(21)19-12-5-3-4-11(8-12)15-10-18-13-6-1-2-7-14(13)20-15/h1-8,10H,9H2,(H,19,21) | PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human)) | BDBM107141
(US8592415, 26)Show SMILES FC(F)(F)C(=O)CC(=O)Nc1cccc(c1)-c1cnc2ccccc2n1 Show InChI InChI=1S/C18H12F3N3O2/c19-18(20,21)16(25)9-17(26)23-12-5-3-4-11(8-12)15-10-22-13-6-1-2-7-14(13)24-15/h1-8,10H,9H2,(H,23,26) | PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human)) | BDBM107146
(US8592415, 31)Show SMILES CC(Nc1cccc(c1)-c1cnc2ccccc2n1)=C1CCOC1=O |w:1.0| Show InChI InChI=1S/C20H17N3O2/c1-13(16-9-10-25-20(16)24)22-15-6-4-5-14(11-15)19-12-21-17-7-2-3-8-18(17)23-19/h2-8,11-12,22H,9-10H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM107140
(US8592415, 25)Show InChI InChI=1S/C17H15N3OS/c1-22-11-17(21)19-13-6-4-5-12(9-13)16-10-18-14-7-2-3-8-15(14)20-16/h2-10H,11H2,1H3,(H,19,21) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM107148
(US8592415, 33)Show SMILES O=C(CN1CCN(CC1)c1ccncc1)Nc1cccc(c1)-c1cnc2ccccc2n1 Show InChI InChI=1S/C25H24N6O/c32-25(18-30-12-14-31(15-13-30)21-8-10-26-11-9-21)28-20-5-3-4-19(16-20)24-17-27-22-6-1-2-7-23(22)29-24/h1-11,16-17H,12-15,18H2,(H,28,32) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM107140
(US8592415, 25)Show InChI InChI=1S/C17H15N3OS/c1-22-11-17(21)19-13-6-4-5-12(9-13)16-10-18-14-7-2-3-8-15(14)20-16/h2-10H,11H2,1H3,(H,19,21) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human)) | BDBM107151
(US8592415, 36)Show SMILES NS(=O)(=O)CCC(=O)Nc1cccc(c1)-c1cnc2ccccc2n1 Show InChI InChI=1S/C17H16N4O3S/c18-25(23,24)9-8-17(22)20-13-5-3-4-12(10-13)16-11-19-14-6-1-2-7-15(14)21-16/h1-7,10-11H,8-9H2,(H,20,22)(H2,18,23,24) | PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human)) | BDBM107145
(US8592415, 30)Show InChI InChI=1S/C18H15N3O2S/c1-12(22)24-11-18(23)20-14-6-4-5-13(9-14)17-10-19-15-7-2-3-8-16(15)21-17/h2-10H,11H2,1H3,(H,20,23) | PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM107150
(US8592415, 35)Show InChI InChI=1S/C20H21N5O/c26-20(14-25-10-8-21-9-11-25)23-16-5-3-4-15(12-16)19-13-22-17-6-1-2-7-18(17)24-19/h1-7,12-13,21H,8-11,14H2,(H,23,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM107131
(US8592415, 16)Show SMILES O=C(CN1CCN(CC1)c1ccccc1)Nc1cccc(c1)-c1cnc2ccccc2n1 Show InChI InChI=1S/C26H25N5O/c32-26(19-30-13-15-31(16-14-30)22-9-2-1-3-10-22)28-21-8-6-7-20(17-21)25-18-27-23-11-4-5-12-24(23)29-25/h1-12,17-18H,13-16,19H2,(H,28,32) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM107124
(US8592415, 8)Show InChI InChI=1S/C17H12N4O/c18-9-8-17(22)20-13-5-3-4-12(10-13)16-11-19-14-6-1-2-7-15(14)21-16/h1-7,10-11H,8H2,(H,20,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.81E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM107130
(US8592415, 15)Show InChI InChI=1S/C15H13N3O2S/c1-21(19,20)18-12-6-4-5-11(9-12)15-10-16-13-7-2-3-8-14(13)17-15/h2-10,18H,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 1.85E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM107119
(US8592415, 3)Show InChI InChI=1S/C20H20N4O/c25-20(14-24-10-3-4-11-24)22-16-7-5-6-15(12-16)19-13-21-17-8-1-2-9-18(17)23-19/h1-2,5-9,12-13H,3-4,10-11,14H2,(H,22,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM107124
(US8592415, 8)Show InChI InChI=1S/C17H12N4O/c18-9-8-17(22)20-13-5-3-4-12(10-13)16-11-19-14-6-1-2-7-15(14)21-16/h1-7,10-11H,8H2,(H,20,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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DrugBank
antibodypedia
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| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human)) | BDBM107119
(US8592415, 3)Show InChI InChI=1S/C20H20N4O/c25-20(14-24-10-3-4-11-24)22-16-7-5-6-15(12-16)19-13-21-17-8-1-2-9-18(17)23-19/h1-2,5-9,12-13H,3-4,10-11,14H2,(H,22,25) | PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human)) | BDBM107125
(US8592415, 9)Show InChI InChI=1S/C21H22N4O/c26-21(15-25-11-4-1-5-12-25)23-17-8-6-7-16(13-17)20-14-22-18-9-2-3-10-19(18)24-20/h2-3,6-10,13-14H,1,4-5,11-12,15H2,(H,23,26) | PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM107125
(US8592415, 9)Show InChI InChI=1S/C21H22N4O/c26-21(15-25-11-4-1-5-12-25)23-17-8-6-7-16(13-17)20-14-22-18-9-2-3-10-19(18)24-20/h2-3,6-10,13-14H,1,4-5,11-12,15H2,(H,23,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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DrugBank
antibodypedia
GoogleScholar
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| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human)) | BDBM67818
(2-chloranyl-N-(3-quinoxalin-2-ylphenyl)ethanamide ...)Show InChI InChI=1S/C16H12ClN3O/c17-9-16(21)19-12-5-3-4-11(8-12)15-10-18-13-6-1-2-7-14(13)20-15/h1-8,10H,9H2,(H,19,21) | PDB
KEGG
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| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human)) | BDBM107120
(US8592415, 4)Show SMILES Clc1ccc(cc1)N1CCN(CC(=O)Nc2cccc(c2)-c2cnc3ccccc3n2)CC1 Show InChI InChI=1S/C26H24ClN5O/c27-20-8-10-22(11-9-20)32-14-12-31(13-15-32)18-26(33)29-21-5-3-4-19(16-21)25-17-28-23-6-1-2-7-24(23)30-25/h1-11,16-17H,12-15,18H2,(H,29,33) | PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
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DrugBank
antibodypedia
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| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM107150
(US8592415, 35)Show InChI InChI=1S/C20H21N5O/c26-20(14-25-10-8-21-9-11-25)23-16-5-3-4-15(12-16)19-13-22-17-6-1-2-7-18(17)24-19/h1-7,12-13,21H,8-11,14H2,(H,23,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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DrugBank
antibodypedia
GoogleScholar
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| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM107150
(US8592415, 35)Show InChI InChI=1S/C20H21N5O/c26-20(14-25-10-8-21-9-11-25)23-16-5-3-4-15(12-16)19-13-22-17-6-1-2-7-18(17)24-19/h1-7,12-13,21H,8-11,14H2,(H,23,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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DrugBank
antibodypedia
GoogleScholar
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| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM67818
(2-chloranyl-N-(3-quinoxalin-2-ylphenyl)ethanamide ...)Show InChI InChI=1S/C16H12ClN3O/c17-9-16(21)19-12-5-3-4-11(8-12)15-10-18-13-6-1-2-7-14(13)20-15/h1-8,10H,9H2,(H,19,21) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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DrugBank
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| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM107119
(US8592415, 3)Show InChI InChI=1S/C20H20N4O/c25-20(14-24-10-3-4-11-24)22-16-7-5-6-15(12-16)19-13-21-17-8-1-2-9-18(17)23-19/h1-2,5-9,12-13H,3-4,10-11,14H2,(H,22,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
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antibodypedia
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| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human)) | BDBM107124
(US8592415, 8)Show InChI InChI=1S/C17H12N4O/c18-9-8-17(22)20-13-5-3-4-12(10-13)16-11-19-14-6-1-2-7-15(14)21-16/h1-7,10-11H,8H2,(H,20,22) | PDB
KEGG
UniProtKB/SwissProt
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| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM107125
(US8592415, 9)Show InChI InChI=1S/C21H22N4O/c26-21(15-25-11-4-1-5-12-25)23-17-8-6-7-16(13-17)20-14-22-18-9-2-3-10-19(18)24-20/h2-3,6-10,13-14H,1,4-5,11-12,15H2,(H,23,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM67818
(2-chloranyl-N-(3-quinoxalin-2-ylphenyl)ethanamide ...)Show InChI InChI=1S/C16H12ClN3O/c17-9-16(21)19-12-5-3-4-11(8-12)15-10-18-13-6-1-2-7-14(13)20-15/h1-8,10H,9H2,(H,19,21) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
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| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM107119
(US8592415, 3)Show InChI InChI=1S/C20H20N4O/c25-20(14-24-10-3-4-11-24)22-16-7-5-6-15(12-16)19-13-21-17-8-1-2-9-18(17)23-19/h1-2,5-9,12-13H,3-4,10-11,14H2,(H,22,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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DrugBank
antibodypedia
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| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM107120
(US8592415, 4)Show SMILES Clc1ccc(cc1)N1CCN(CC(=O)Nc2cccc(c2)-c2cnc3ccccc3n2)CC1 Show InChI InChI=1S/C26H24ClN5O/c27-20-8-10-22(11-9-20)32-14-12-31(13-15-32)18-26(33)29-21-5-3-4-19(16-21)25-17-28-23-6-1-2-7-24(23)30-25/h1-11,16-17H,12-15,18H2,(H,29,33) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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antibodypedia
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| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human)) | BDBM107150
(US8592415, 35)Show InChI InChI=1S/C20H21N5O/c26-20(14-25-10-8-21-9-11-25)23-16-5-3-4-15(12-16)19-13-22-17-6-1-2-7-18(17)24-19/h1-7,12-13,21H,8-11,14H2,(H,23,26) | PDB
KEGG
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| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM107120
(US8592415, 4)Show SMILES Clc1ccc(cc1)N1CCN(CC(=O)Nc2cccc(c2)-c2cnc3ccccc3n2)CC1 Show InChI InChI=1S/C26H24ClN5O/c27-20-8-10-22(11-9-20)32-14-12-31(13-15-32)18-26(33)29-21-5-3-4-19(16-21)25-17-28-23-6-1-2-7-24(23)30-25/h1-11,16-17H,12-15,18H2,(H,29,33) | PDB
Reactome pathway
KEGG
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antibodypedia
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| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM107131
(US8592415, 16)Show SMILES O=C(CN1CCN(CC1)c1ccccc1)Nc1cccc(c1)-c1cnc2ccccc2n1 Show InChI InChI=1S/C26H25N5O/c32-26(19-30-13-15-31(16-14-30)22-9-2-1-3-10-22)28-21-8-6-7-20(17-21)25-18-27-23-11-4-5-12-24(23)29-25/h1-12,17-18H,13-16,19H2,(H,28,32) | PDB
Reactome pathway
KEGG
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| Purchase
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PC sid
UniChem
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| US Patent
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human)) | BDBM107131
(US8592415, 16)Show SMILES O=C(CN1CCN(CC1)c1ccccc1)Nc1cccc(c1)-c1cnc2ccccc2n1 Show InChI InChI=1S/C26H25N5O/c32-26(19-30-13-15-31(16-14-30)22-9-2-1-3-10-22)28-21-8-6-7-20(17-21)25-18-27-23-11-4-5-12-24(23)29-25/h1-12,17-18H,13-16,19H2,(H,28,32) | PDB
KEGG
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| Purchase
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PC sid
UniChem
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| US Patent
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM107127
(US8592415, 12)Show InChI InChI=1S/C19H13N3O2/c23-19(18-9-4-10-24-18)21-14-6-3-5-13(11-14)17-12-20-15-7-1-2-8-16(15)22-17/h1-12H,(H,21,23) | PDB
Reactome pathway
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| Purchase
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UniChem
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| US Patent
| n/a | n/a | 2.46E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM107129
(US8592415, 14)Show InChI InChI=1S/C18H15N3O/c22-18(12-8-9-12)20-14-5-3-4-13(10-14)17-11-19-15-6-1-2-7-16(15)21-17/h1-7,10-12H,8-9H2,(H,20,22) | PDB
Reactome pathway
KEGG
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B.MOAD
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| Purchase
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PC sid
UniChem
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| US Patent
| n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM67663
(1-methyl-3-(3-quinoxalin-2-ylphenyl)thiourea | 1-m...)Show InChI InChI=1S/C16H14N4S/c1-17-16(21)19-12-6-4-5-11(9-12)15-10-18-13-7-2-3-8-14(13)20-15/h2-10H,1H3,(H2,17,19,21) | PDB
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UniChem
| US Patent
| n/a | n/a | 2.55E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM107135
(US8592415, 20)Show InChI InChI=1S/C20H20N4O2/c25-20(14-24-8-10-26-11-9-24)22-16-5-3-4-15(12-16)19-13-21-17-6-1-2-7-18(17)23-19/h1-7,12-13H,8-11,14H2,(H,22,25) | PDB
Reactome pathway
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| US Patent
| n/a | n/a | 3.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM107121
(US8592415, 5)Show InChI InChI=1S/C18H16ClN3O/c19-10-4-9-18(23)21-14-6-3-5-13(11-14)17-12-20-15-7-1-2-8-16(15)22-17/h1-3,5-8,11-12H,4,9-10H2,(H,21,23) | PDB
Reactome pathway
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| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM107122
(US8592415, 6)Show InChI InChI=1S/C17H15N3O/c1-2-17(21)19-13-7-5-6-12(10-13)16-11-18-14-8-3-4-9-15(14)20-16/h3-11H,2H2,1H3,(H,19,21) | PDB
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| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM107127
(US8592415, 12)Show InChI InChI=1S/C19H13N3O2/c23-19(18-9-4-10-24-18)21-14-6-3-5-13(11-14)17-12-20-15-7-1-2-8-16(15)22-17/h1-12H,(H,21,23) | PDB
Reactome pathway
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| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM107135
(US8592415, 20)Show InChI InChI=1S/C20H20N4O2/c25-20(14-24-8-10-26-11-9-24)22-16-5-3-4-15(12-16)19-13-21-17-6-1-2-7-18(17)23-19/h1-7,12-13H,8-11,14H2,(H,22,25) | PDB
Reactome pathway
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| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human)) | BDBM107121
(US8592415, 5)Show InChI InChI=1S/C18H16ClN3O/c19-10-4-9-18(23)21-14-6-3-5-13(11-14)17-12-20-15-7-1-2-8-16(15)22-17/h1-3,5-8,11-12H,4,9-10H2,(H,21,23) | PDB
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| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human)) | BDBM107122
(US8592415, 6)Show InChI InChI=1S/C17H15N3O/c1-2-17(21)19-13-7-5-6-12(10-13)16-11-18-14-8-3-4-9-15(14)20-16/h3-11H,2H2,1H3,(H,19,21) | PDB
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| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM107127
(US8592415, 12)Show InChI InChI=1S/C19H13N3O2/c23-19(18-9-4-10-24-18)21-14-6-3-5-13(11-14)17-12-20-15-7-1-2-8-16(15)22-17/h1-12H,(H,21,23) | PDB
Reactome pathway
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| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM107130
(US8592415, 15)Show InChI InChI=1S/C15H13N3O2S/c1-21(19,20)18-12-6-4-5-11(9-12)15-10-16-13-7-2-3-8-14(13)17-15/h2-10,18H,1H3 | PDB
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| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM107132
(US8592415, 17)Show SMILES CN1CCN(CC(=O)Nc2cccc(c2)-c2cnc3ccccc3n2)CC1 Show InChI InChI=1S/C21H23N5O/c1-25-9-11-26(12-10-25)15-21(27)23-17-6-4-5-16(13-17)20-14-22-18-7-2-3-8-19(18)24-20/h2-8,13-14H,9-12,15H2,1H3,(H,23,27) | PDB
Reactome pathway
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UniChem
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| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM107136
(US8592415, 21)Show InChI InChI=1S/C17H14ClN3O/c1-11(18)17(22)20-13-6-4-5-12(9-13)16-10-19-14-7-2-3-8-15(14)21-16/h2-11H,1H3,(H,20,22) | PDB
Reactome pathway
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UniChem
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| US Patent
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human)) | BDBM107127
(US8592415, 12)Show InChI InChI=1S/C19H13N3O2/c23-19(18-9-4-10-24-18)21-14-6-3-5-13(11-14)17-12-20-15-7-1-2-8-16(15)22-17/h1-12H,(H,21,23) | PDB
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| US Patent
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM107122
(US8592415, 6)Show InChI InChI=1S/C17H15N3O/c1-2-17(21)19-13-7-5-6-12(10-13)16-11-18-14-8-3-4-9-15(14)20-16/h3-11H,2H2,1H3,(H,19,21) | PDB
Reactome pathway
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UniChem
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| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM107118
(US8592415, 2)Show InChI InChI=1S/C18H18N4O/c1-22(2)12-18(23)20-14-7-5-6-13(10-14)17-11-19-15-8-3-4-9-16(15)21-17/h3-11H,12H2,1-2H3,(H,20,23) | PDB
Reactome pathway
KEGG
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UniChem
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| US Patent
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM107121
(US8592415, 5)Show InChI InChI=1S/C18H16ClN3O/c19-10-4-9-18(23)21-14-6-3-5-13(11-14)17-12-20-15-7-1-2-8-16(15)22-17/h1-3,5-8,11-12H,4,9-10H2,(H,21,23) | PDB
Reactome pathway
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UniChem
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| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM107136
(US8592415, 21)Show InChI InChI=1S/C17H14ClN3O/c1-11(18)17(22)20-13-6-4-5-12(9-13)16-10-19-14-7-2-3-8-15(14)21-16/h2-11H,1H3,(H,20,22) | PDB
Reactome pathway
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| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM107129
(US8592415, 14)Show InChI InChI=1S/C18H15N3O/c22-18(12-8-9-12)20-14-5-3-4-13(10-14)17-11-19-15-6-1-2-7-16(15)21-17/h1-7,10-12H,8-9H2,(H,20,22) | PDB
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| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM107130
(US8592415, 15)Show InChI InChI=1S/C15H13N3O2S/c1-21(19,20)18-12-6-4-5-11(9-12)15-10-16-13-7-2-3-8-14(13)17-15/h2-10,18H,1H3 | PDB
Reactome pathway
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| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM107126
(US8592415, 10)Show SMILES COc1ccc(NC(=O)Nc2cccc(c2)-c2cnc3ccccc3n2)cc1 Show InChI InChI=1S/C22H18N4O2/c1-28-18-11-9-16(10-12-18)24-22(27)25-17-6-4-5-15(13-17)21-14-23-19-7-2-3-8-20(19)26-21/h2-14H,1H3,(H2,24,25,27) | PDB
Reactome pathway
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| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM107132
(US8592415, 17)Show SMILES CN1CCN(CC(=O)Nc2cccc(c2)-c2cnc3ccccc3n2)CC1 Show InChI InChI=1S/C21H23N5O/c1-25-9-11-26(12-10-25)15-21(27)23-17-6-4-5-16(13-17)20-14-22-18-7-2-3-8-19(18)24-20/h2-8,13-14H,9-12,15H2,1H3,(H,23,27) | PDB
Reactome pathway
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UniChem
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| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human)) | BDBM107123
(US8592415, 7)Show InChI InChI=1S/C18H14N6O/c25-18(10-24-12-19-11-21-24)22-14-5-3-4-13(8-14)17-9-20-15-6-1-2-7-16(15)23-17/h1-9,11-12H,10H2,(H,22,25) | PDB
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| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human)) | BDBM107128
(US8592415, 13)Show InChI InChI=1S/C18H13N3O2S2/c22-25(23,18-9-4-10-24-18)21-14-6-3-5-13(11-14)17-12-19-15-7-1-2-8-16(15)20-17/h1-12,21H | PDB
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| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human)) | BDBM107135
(US8592415, 20)Show InChI InChI=1S/C20H20N4O2/c25-20(14-24-8-10-26-11-9-24)22-16-5-3-4-15(12-16)19-13-21-17-6-1-2-7-18(17)23-19/h1-7,12-13H,8-11,14H2,(H,22,25) | PDB
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| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM107123
(US8592415, 7)Show InChI InChI=1S/C18H14N6O/c25-18(10-24-12-19-11-21-24)22-14-5-3-4-13(8-14)17-9-20-15-6-1-2-7-16(15)23-17/h1-9,11-12H,10H2,(H,22,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM107134
(US8592415, 19)Show InChI InChI=1S/C17H14ClN3O/c18-9-8-17(22)20-13-5-3-4-12(10-13)16-11-19-14-6-1-2-7-15(14)21-16/h1-7,10-11H,8-9H2,(H,20,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM107123
(US8592415, 7)Show InChI InChI=1S/C18H14N6O/c25-18(10-24-12-19-11-21-24)22-14-5-3-4-13(8-14)17-9-20-15-6-1-2-7-16(15)23-17/h1-9,11-12H,10H2,(H,22,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM67663
(1-methyl-3-(3-quinoxalin-2-ylphenyl)thiourea | 1-m...)Show InChI InChI=1S/C16H14N4S/c1-17-16(21)19-12-6-4-5-11(9-12)15-10-18-13-7-2-3-8-14(13)20-15/h2-10H,1H3,(H2,17,19,21) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human)) | BDBM107136
(US8592415, 21)Show InChI InChI=1S/C17H14ClN3O/c1-11(18)17(22)20-13-6-4-5-12(9-13)16-10-19-14-7-2-3-8-15(14)21-16/h2-11H,1H3,(H,20,22) | PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM107118
(US8592415, 2)Show InChI InChI=1S/C18H18N4O/c1-22(2)12-18(23)20-14-7-5-6-13(10-14)17-11-19-15-8-3-4-9-16(15)21-17/h3-11H,12H2,1-2H3,(H,20,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM107126
(US8592415, 10)Show SMILES COc1ccc(NC(=O)Nc2cccc(c2)-c2cnc3ccccc3n2)cc1 Show InChI InChI=1S/C22H18N4O2/c1-28-18-11-9-16(10-12-18)24-22(27)25-17-6-4-5-15(13-17)21-14-23-19-7-2-3-8-20(19)26-21/h2-14H,1H3,(H2,24,25,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM107128
(US8592415, 13)Show InChI InChI=1S/C18H13N3O2S2/c22-25(23,18-9-4-10-24-18)21-14-6-3-5-13(11-14)17-12-19-15-7-1-2-8-16(15)20-17/h1-12,21H | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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| Purchase
PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM107126
(US8592415, 10)Show SMILES COc1ccc(NC(=O)Nc2cccc(c2)-c2cnc3ccccc3n2)cc1 Show InChI InChI=1S/C22H18N4O2/c1-28-18-11-9-16(10-12-18)24-22(27)25-17-6-4-5-15(13-17)21-14-23-19-7-2-3-8-20(19)26-21/h2-14H,1H3,(H2,24,25,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM107121
(US8592415, 5)Show InChI InChI=1S/C18H16ClN3O/c19-10-4-9-18(23)21-14-6-3-5-13(11-14)17-12-20-15-7-1-2-8-16(15)22-17/h1-3,5-8,11-12H,4,9-10H2,(H,21,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM107128
(US8592415, 13)Show InChI InChI=1S/C18H13N3O2S2/c22-25(23,18-9-4-10-24-18)21-14-6-3-5-13(11-14)17-12-19-15-7-1-2-8-16(15)20-17/h1-12,21H | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human)) | BDBM107129
(US8592415, 14)Show InChI InChI=1S/C18H15N3O/c22-18(12-8-9-12)20-14-5-3-4-13(10-14)17-11-19-15-6-1-2-7-16(15)21-17/h1-7,10-12H,8-9H2,(H,20,22) | PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM107118
(US8592415, 2)Show InChI InChI=1S/C18H18N4O/c1-22(2)12-18(23)20-14-7-5-6-13(10-14)17-11-19-15-8-3-4-9-16(15)21-17/h3-11H,12H2,1-2H3,(H,20,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM107122
(US8592415, 6)Show InChI InChI=1S/C17H15N3O/c1-2-17(21)19-13-7-5-6-12(10-13)16-11-18-14-8-3-4-9-15(14)20-16/h3-11H,2H2,1H3,(H,19,21) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human)) | BDBM107126
(US8592415, 10)Show SMILES COc1ccc(NC(=O)Nc2cccc(c2)-c2cnc3ccccc3n2)cc1 Show InChI InChI=1S/C22H18N4O2/c1-28-18-11-9-16(10-12-18)24-22(27)25-17-6-4-5-15(13-17)21-14-23-19-7-2-3-8-20(19)26-21/h2-14H,1H3,(H2,24,25,27) | PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human)) | BDBM107132
(US8592415, 17)Show SMILES CN1CCN(CC(=O)Nc2cccc(c2)-c2cnc3ccccc3n2)CC1 Show InChI InChI=1S/C21H23N5O/c1-25-9-11-26(12-10-25)15-21(27)23-17-6-4-5-16(13-17)20-14-22-18-7-2-3-8-19(18)24-20/h2-8,13-14H,9-12,15H2,1H3,(H,23,27) | PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM67663
(1-methyl-3-(3-quinoxalin-2-ylphenyl)thiourea | 1-m...)Show InChI InChI=1S/C16H14N4S/c1-17-16(21)19-12-6-4-5-11(9-12)15-10-18-13-7-2-3-8-14(13)20-15/h2-10H,1H3,(H2,17,19,21) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM107129
(US8592415, 14)Show InChI InChI=1S/C18H15N3O/c22-18(12-8-9-12)20-14-5-3-4-13(10-14)17-11-19-15-6-1-2-7-16(15)21-17/h1-7,10-12H,8-9H2,(H,20,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM107132
(US8592415, 17)Show SMILES CN1CCN(CC(=O)Nc2cccc(c2)-c2cnc3ccccc3n2)CC1 Show InChI InChI=1S/C21H23N5O/c1-25-9-11-26(12-10-25)15-21(27)23-17-6-4-5-16(13-17)20-14-22-18-7-2-3-8-19(18)24-20/h2-8,13-14H,9-12,15H2,1H3,(H,23,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM107123
(US8592415, 7)Show InChI InChI=1S/C18H14N6O/c25-18(10-24-12-19-11-21-24)22-14-5-3-4-13(8-14)17-9-20-15-6-1-2-7-16(15)23-17/h1-9,11-12H,10H2,(H,22,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM107134
(US8592415, 19)Show InChI InChI=1S/C17H14ClN3O/c18-9-8-17(22)20-13-5-3-4-12(10-13)16-11-19-14-6-1-2-7-15(14)21-16/h1-7,10-11H,8-9H2,(H,20,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM107135
(US8592415, 20)Show InChI InChI=1S/C20H20N4O2/c25-20(14-24-8-10-26-11-9-24)22-16-5-3-4-15(12-16)19-13-21-17-6-1-2-7-18(17)23-19/h1-7,12-13H,8-11,14H2,(H,22,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM107134
(US8592415, 19)Show InChI InChI=1S/C17H14ClN3O/c18-9-8-17(22)20-13-5-3-4-12(10-13)16-11-19-14-6-1-2-7-15(14)21-16/h1-7,10-11H,8-9H2,(H,20,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human)) | BDBM107118
(US8592415, 2)Show InChI InChI=1S/C18H18N4O/c1-22(2)12-18(23)20-14-7-5-6-13(10-14)17-11-19-15-8-3-4-9-16(15)21-17/h3-11H,12H2,1-2H3,(H,20,23) | PDB
KEGG
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PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human)) | BDBM67663
(1-methyl-3-(3-quinoxalin-2-ylphenyl)thiourea | 1-m...)Show InChI InChI=1S/C16H14N4S/c1-17-16(21)19-12-6-4-5-11(9-12)15-10-18-13-7-2-3-8-14(13)20-15/h2-10H,1H3,(H2,17,19,21) | PDB
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UniChem
| US Patent
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human)) | BDBM107130
(US8592415, 15)Show InChI InChI=1S/C15H13N3O2S/c1-21(19,20)18-12-6-4-5-11(9-12)15-10-16-13-7-2-3-8-14(13)17-15/h2-10,18H,1H3 | PDB
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UniChem
| US Patent
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human)) | BDBM107134
(US8592415, 19)Show InChI InChI=1S/C17H14ClN3O/c18-9-8-17(22)20-13-5-3-4-12(10-13)16-11-19-14-6-1-2-7-15(14)21-16/h1-7,10-11H,8-9H2,(H,20,22) | PDB
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PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM107128
(US8592415, 13)Show InChI InChI=1S/C18H13N3O2S2/c22-25(23,18-9-4-10-24-18)21-14-6-3-5-13(11-14)17-12-19-15-7-1-2-8-16(15)20-17/h1-12,21H | PDB
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| US Patent
| n/a | n/a | 5.55E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM107143
(US8592415, 28)Show InChI InChI=1S/C18H15N3O3/c1-12(22)24-11-18(23)20-14-6-4-5-13(9-14)17-10-19-15-7-2-3-8-16(15)21-17/h2-10H,11H2,1H3,(H,20,23) | PDB
Reactome pathway
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| PC cid
PC sid
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| US Patent
| n/a | n/a | 1.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Reaction Biology Corp.; Synerga Limited
US Patent
| Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2. |
US Patent US8592415 (2013)
BindingDB Entry DOI: 10.7270/Q218354P |
More data for this
Ligand-Target Pair | |
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