Found 29 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Carboxypeptidase B2
(Homo sapiens (Human)) | BDBM109264
(US8609710, 40)Show SMILES C[C@H]1CC[C@@H](CC1)n1cnc(C[C@H](CCCN)C(O)=O)c1 |r,wU:4.7,wD:1.0,12.12,(-6.38,5.14,;-5.98,3.65,;-7.07,2.56,;-6.67,1.07,;-5.18,.68,;-4.09,1.76,;-4.49,3.25,;-4.78,-.81,;-5.69,-2.06,;-4.78,-3.3,;-3.32,-2.83,;-1.98,-3.6,;-.65,-2.83,;-.65,-1.29,;.68,-.52,;.68,1.02,;2.02,1.79,;.68,-3.6,;2.02,-2.83,;.68,-5.14,;-3.32,-1.29,)| Show InChI InChI=1S/C16H27N3O2/c1-12-4-6-15(7-5-12)19-10-14(18-11-19)9-13(16(20)21)3-2-8-17/h10-13,15H,2-9,17H2,1H3,(H,20,21)/t12-,13-,15-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| Purchase
MCE
PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited
US Patent
| Assay Description
Enzyme inhibition assay using TAFIa. |
US Patent US8609710 (2013)
BindingDB Entry DOI: 10.7270/Q2KW5DPP |
More data for this
Ligand-Target Pair | |
Carboxypeptidase B2
(Homo sapiens (Human)) | BDBM109265
(US8609710, 35 (2S,4R form))Show SMILES C[C@@H](CN)C[C@@H](Cc1cn(cn1)[C@H]1CC[C@H](C)CC1)C(O)=O |r,wU:12.12,wD:5.5,15.16,1.0,(4.54,-1.29,;3.21,-.52,;3.21,1.02,;4.54,1.79,;1.87,-1.29,;1.87,-2.83,;.54,-3.6,;-.79,-2.83,;-.79,-1.29,;-2.26,-.81,;-3.16,-2.06,;-2.26,-3.3,;-2.66,.68,;-4.14,1.07,;-4.54,2.56,;-3.45,3.65,;-3.85,5.14,;-1.97,3.25,;-1.57,1.76,;3.21,-3.6,;3.21,-5.14,;4.54,-2.83,)| Show InChI InChI=1S/C17H29N3O2/c1-12-3-5-16(6-4-12)20-10-15(19-11-20)8-14(17(21)22)7-13(2)9-18/h10-14,16H,3-9,18H2,1-2H3,(H,21,22)/t12-,13-,14+,16-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 5.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited
US Patent
| Assay Description
Enzyme inhibition assay using TAFIa. |
US Patent US8609710 (2013)
BindingDB Entry DOI: 10.7270/Q2KW5DPP |
More data for this
Ligand-Target Pair | |
Carboxypeptidase B2
(Homo sapiens (Human)) | BDBM109258
(US8609710, 34 (2S,4S form))Show SMILES C[C@H](CN)C[C@@H](Cc1cn(cn1)[C@H]1CC[C@H](C)CC1)C(O)=O |r,wU:12.12,1.0,wD:5.5,15.16,(4.54,-1.29,;3.21,-.52,;3.21,1.02,;4.54,1.79,;1.87,-1.29,;1.87,-2.83,;.54,-3.6,;-.79,-2.83,;-.79,-1.29,;-2.26,-.81,;-3.16,-2.06,;-2.26,-3.3,;-2.66,.68,;-4.14,1.07,;-4.54,2.56,;-3.45,3.65,;-3.85,5.14,;-1.97,3.25,;-1.57,1.76,;3.21,-3.6,;3.21,-5.14,;4.54,-2.83,)| Show InChI InChI=1S/C17H29N3O2/c1-12-3-5-16(6-4-12)20-10-15(19-11-20)8-14(17(21)22)7-13(2)9-18/h10-14,16H,3-9,18H2,1-2H3,(H,21,22)/t12-,13-,14-,16-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 5.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited
US Patent
| Assay Description
Enzyme inhibition assay using TAFIa. |
US Patent US8609710 (2013)
BindingDB Entry DOI: 10.7270/Q2KW5DPP |
More data for this
Ligand-Target Pair | |
Carboxypeptidase B2
(Homo sapiens (Human)) | BDBM109254
(US8609710, 25)Show SMILES C[C@H](CN)OC(Cc1cn(cn1)[C@H]1CC[C@H](C)CC1)C(O)=O |r,wU:12.12,1.0,wD:15.16,(4.54,-1.29,;3.21,-.52,;3.21,1.02,;4.54,1.79,;1.87,-1.29,;1.87,-2.83,;.54,-3.6,;-.79,-2.83,;-.79,-1.29,;-2.26,-.81,;-3.16,-2.06,;-2.26,-3.3,;-2.66,.68,;-4.14,1.07,;-4.54,2.56,;-3.45,3.65,;-3.85,5.14,;-1.97,3.25,;-1.57,1.76,;3.21,-3.6,;3.21,-5.14,;4.54,-2.83,)| Show InChI InChI=1S/C16H27N3O3/c1-11-3-5-14(6-4-11)19-9-13(18-10-19)7-15(16(20)21)22-12(2)8-17/h9-12,14-15H,3-8,17H2,1-2H3,(H,20,21)/t11-,12-,14-,15?/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited
US Patent
| Assay Description
Enzyme inhibition assay using TAFIa. |
US Patent US8609710 (2013)
BindingDB Entry DOI: 10.7270/Q2KW5DPP |
More data for this
Ligand-Target Pair | |
Carboxypeptidase B2
(Homo sapiens (Human)) | BDBM109256
(US8609710, 33)Show InChI InChI=1S/C17H29N3O2/c1-17(2)7-3-6-15(10-17)20-11-14(19-12-20)9-13(16(21)22)5-4-8-18/h11-13,15H,3-10,18H2,1-2H3,(H,21,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 7.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited
US Patent
| Assay Description
Enzyme inhibition assay using TAFIa. |
US Patent US8609710 (2013)
BindingDB Entry DOI: 10.7270/Q2KW5DPP |
More data for this
Ligand-Target Pair | |
Carboxypeptidase B2
(Homo sapiens (Human)) | BDBM109252
(US8609710, 15 (2S form))Show SMILES C[C@H]1CC[C@@H](CC1)n1cnc(C[C@H](CCCN)C(O)=O)c1 |r,wU:4.7,wD:1.0,12.12,(-3.85,5.14,;-3.45,3.65,;-4.54,2.56,;-4.14,1.07,;-2.66,.68,;-1.57,1.76,;-1.97,3.25,;-2.26,-.81,;-3.16,-2.06,;-2.26,-3.3,;-.79,-2.83,;.54,-3.6,;1.87,-2.83,;1.87,-1.29,;3.21,-.52,;3.21,1.02,;4.54,1.79,;3.21,-3.6,;3.21,-5.14,;4.54,-2.83,;-.79,-1.29,)| Show InChI InChI=1S/C16H27N3O2/c1-12-4-6-15(7-5-12)19-10-14(18-11-19)9-13(16(20)21)3-2-8-17/h10-13,15H,2-9,17H2,1H3,(H,20,21)/t12-,13-,15-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 7.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited
US Patent
| Assay Description
Enzyme inhibition assay using TAFIa. |
US Patent US8609710 (2013)
BindingDB Entry DOI: 10.7270/Q2KW5DPP |
More data for this
Ligand-Target Pair | |
Carboxypeptidase B2
(Homo sapiens (Human)) | BDBM109253
(US8609710, 24)Show SMILES C[C@H]1CC[C@@H](CC1)n1cnc(CC(OCCN)C(O)=O)c1 |r,wU:4.7,wD:1.0,(-3.85,5.14,;-3.45,3.65,;-4.54,2.56,;-4.14,1.07,;-2.66,.68,;-1.57,1.76,;-1.97,3.25,;-2.26,-.81,;-3.16,-2.06,;-2.26,-3.3,;-.79,-2.83,;.54,-3.6,;1.87,-2.83,;1.87,-1.29,;3.21,-.52,;3.21,1.02,;4.54,1.79,;3.21,-3.6,;3.21,-5.14,;4.54,-2.83,;-.79,-1.29,)| Show InChI InChI=1S/C15H25N3O3/c1-11-2-4-13(5-3-11)18-9-12(17-10-18)8-14(15(19)20)21-7-6-16/h9-11,13-14H,2-8,16H2,1H3,(H,19,20)/t11-,13-,14? | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 8.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited
US Patent
| Assay Description
Enzyme inhibition assay using TAFIa. |
US Patent US8609710 (2013)
BindingDB Entry DOI: 10.7270/Q2KW5DPP |
More data for this
Ligand-Target Pair | |
Carboxypeptidase B2
(Homo sapiens (Human)) | BDBM109238
(US8609710, 2)Show SMILES C[C@H]1CC[C@@H](CC1)n1cnc(CC(CCCN)C(O)=O)c1 |r,wU:4.7,wD:1.0,(-3.85,5.14,;-3.45,3.65,;-4.54,2.56,;-4.14,1.07,;-2.66,.68,;-1.57,1.76,;-1.97,3.25,;-2.26,-.81,;-3.16,-2.06,;-2.26,-3.3,;-.79,-2.83,;.54,-3.6,;1.87,-2.83,;1.87,-1.29,;3.21,-.52,;3.21,1.02,;4.54,1.79,;3.21,-3.6,;3.21,-5.14,;4.54,-2.83,;-.79,-1.29,)| Show InChI InChI=1S/C16H27N3O2/c1-12-4-6-15(7-5-12)19-10-14(18-11-19)9-13(16(20)21)3-2-8-17/h10-13,15H,2-9,17H2,1H3,(H,20,21)/t12-,13?,15- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 8.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited
US Patent
| Assay Description
Enzyme inhibition assay using TAFIa. |
US Patent US8609710 (2013)
BindingDB Entry DOI: 10.7270/Q2KW5DPP |
More data for this
Ligand-Target Pair | |
Carboxypeptidase B2
(Homo sapiens (Human)) | BDBM109239
(US8609710, 3)Show SMILES CC[C@H]1CC[C@@H](CC1)n1cnc(CC(CCCN)C(O)=O)c1 |r,wU:5.8,wD:2.1,(-4.94,5.34,;-3.45,4.94,;-3.05,3.45,;-4.14,2.36,;-3.74,.87,;-2.26,.48,;-1.17,1.57,;-1.57,3.05,;-1.86,-1.01,;-2.76,-2.26,;-1.86,-3.5,;-.39,-3.03,;.94,-3.8,;2.27,-3.03,;2.27,-1.49,;3.61,-.72,;3.61,.82,;4.94,1.59,;3.61,-3.8,;3.61,-5.34,;4.94,-3.03,;-.39,-1.49,)| Show InChI InChI=1S/C17H29N3O2/c1-2-13-5-7-16(8-6-13)20-11-15(19-12-20)10-14(17(21)22)4-3-9-18/h11-14,16H,2-10,18H2,1H3,(H,21,22)/t13-,14?,16- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 8.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited
US Patent
| Assay Description
Enzyme inhibition assay using TAFIa. |
US Patent US8609710 (2013)
BindingDB Entry DOI: 10.7270/Q2KW5DPP |
More data for this
Ligand-Target Pair | |
Carboxypeptidase B2
(Homo sapiens (Human)) | BDBM109263
(US8609710, 39)Show SMILES C[C@H]1CC[C@H](CC1)n1cnc(CC(CCCN)C(O)=O)c1 |r,wU:1.0,4.7,(-3.85,5.14,;-3.45,3.65,;-1.97,3.25,;-1.57,1.76,;-2.66,.68,;-4.14,1.07,;-4.54,2.56,;-2.26,-.81,;-3.16,-2.06,;-2.26,-3.3,;-.79,-2.83,;.54,-3.6,;1.87,-2.83,;1.87,-1.29,;3.21,-.52,;3.21,1.02,;4.54,1.79,;3.21,-3.6,;3.21,-5.14,;4.54,-2.83,;-.79,-1.29,)| Show InChI InChI=1S/C16H27N3O2/c1-12-4-6-15(7-5-12)19-10-14(18-11-19)9-13(16(20)21)3-2-8-17/h10-13,15H,2-9,17H2,1H3,(H,20,21)/t12-,13?,15+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 9.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited
US Patent
| Assay Description
Enzyme inhibition assay using TAFIa. |
US Patent US8609710 (2013)
BindingDB Entry DOI: 10.7270/Q2KW5DPP |
More data for this
Ligand-Target Pair | |
Carboxypeptidase B2
(Homo sapiens (Human)) | BDBM109262
(US8609710, 38)Show SMILES NCCCC(Cc1cn(cn1)[C@H]1CC[C@@H](CC1)Oc1ccncc1)C(O)=O |r,wU:11.11,wD:14.18,(5.63,1.13,;4.3,.36,;4.3,-1.18,;2.96,-1.95,;2.96,-3.49,;1.63,-4.26,;.29,-3.49,;.29,-1.95,;-1.17,-1.48,;-2.08,-2.72,;-1.17,-3.97,;-1.57,.01,;-3.06,.41,;-3.46,1.89,;-2.37,2.98,;-.88,2.58,;-.48,1.1,;-2.76,4.47,;-4.3,4.47,;-5.07,5.8,;-6.61,5.8,;-7.38,4.47,;-6.61,3.14,;-5.07,3.14,;4.3,-4.26,;4.3,-5.8,;5.63,-3.49,)| Show InChI InChI=1S/C20H28N4O3/c21-9-1-2-15(20(25)26)12-16-13-24(14-23-16)17-3-5-18(6-4-17)27-19-7-10-22-11-8-19/h7-8,10-11,13-15,17-18H,1-6,9,12,21H2,(H,25,26)/t15?,17-,18- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 9.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited
US Patent
| Assay Description
Enzyme inhibition assay using TAFIa. |
US Patent US8609710 (2013)
BindingDB Entry DOI: 10.7270/Q2KW5DPP |
More data for this
Ligand-Target Pair | |
Carboxypeptidase B2
(Homo sapiens (Human)) | BDBM109260
(US8609710, 36)Show SMILES CCC(CN)CC(Cc1cn(cn1)[C@H]1CC[C@H](C)CC1)C(O)=O |r,wU:13.13,wD:16.17,(4.8,-.52,;3.47,-1.29,;2.14,-.52,;2.14,1.02,;3.47,1.79,;.8,-1.29,;.8,-2.83,;-.53,-3.6,;-1.86,-2.83,;-1.86,-1.29,;-3.33,-.81,;-4.23,-2.06,;-3.33,-3.3,;-3.73,.68,;-5.22,1.07,;-5.61,2.56,;-4.53,3.65,;-4.92,5.14,;-3.04,3.25,;-2.64,1.76,;2.14,-3.6,;2.14,-5.14,;3.47,-2.83,)| Show InChI InChI=1S/C18H31N3O2/c1-3-14(10-19)8-15(18(22)23)9-16-11-21(12-20-16)17-6-4-13(2)5-7-17/h11-15,17H,3-10,19H2,1-2H3,(H,22,23)/t13-,14?,15?,17- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited
US Patent
| Assay Description
Enzyme inhibition assay using TAFIa. |
US Patent US8609710 (2013)
BindingDB Entry DOI: 10.7270/Q2KW5DPP |
More data for this
Ligand-Target Pair | |
Carboxypeptidase B2
(Homo sapiens (Human)) | BDBM109249
(US8609710, 13)Show SMILES NCCCC(Cc1cn(cn1)C1C2CC3CC(C2)CC1C3)C(O)=O |TLB:8:11:13:15.16.17,THB:15:14:11:18.16.17,15:16:11:13.14.20,18:19:13:15.16.17,18:16:13:11.20.19,(5.01,2.01,;3.68,1.24,;3.68,-.3,;2.34,-1.07,;2.34,-2.61,;1.01,-3.38,;-.32,-2.61,;-.32,-1.07,;-1.79,-.6,;-2.69,-1.84,;-1.79,-3.09,;-2.56,.74,;-4.05,.92,;-5.01,2.01,;-4.19,3.43,;-4.58,4.92,;-3.47,3.62,;-4.24,2.29,;-1.93,3.62,;-1.93,2.08,;-2.86,3.27,;3.68,-3.38,;3.68,-4.92,;5.01,-2.61,)| Show InChI InChI=1S/C19H29N3O2/c20-3-1-2-14(19(23)24)9-17-10-22(11-21-17)18-15-5-12-4-13(7-15)8-16(18)6-12/h10-16,18H,1-9,20H2,(H,23,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited
US Patent
| Assay Description
Enzyme inhibition assay using TAFIa. |
US Patent US8609710 (2013)
BindingDB Entry DOI: 10.7270/Q2KW5DPP |
More data for this
Ligand-Target Pair | |
Carboxypeptidase B2
(Homo sapiens (Human)) | BDBM109250
(US8609710, 14)Show SMILES NCCCC(Cc1cn(cn1)[C@H]1CC[C@@H](CC1)Oc1ccccc1)C(O)=O |r,wU:11.11,wD:14.18,(6.03,-.04,;4.7,-.81,;4.7,-2.35,;3.36,-3.12,;3.36,-4.66,;2.03,-5.43,;.69,-4.66,;.69,-3.12,;-.77,-2.64,;-1.67,-3.89,;-.77,-5.14,;-1.17,-1.16,;-2.66,-.76,;-3.05,.73,;-1.97,1.82,;-.48,1.42,;-.08,-.07,;-2.36,3.31,;-3.45,4.39,;-3.05,5.88,;-4.14,6.97,;-5.63,6.57,;-6.03,5.08,;-4.94,4,;4.7,-5.43,;4.7,-6.97,;6.03,-4.66,)| Show InChI InChI=1S/C21H29N3O3/c22-12-4-5-16(21(25)26)13-17-14-24(15-23-17)18-8-10-20(11-9-18)27-19-6-2-1-3-7-19/h1-3,6-7,14-16,18,20H,4-5,8-13,22H2,(H,25,26)/t16?,18-,20- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited
US Patent
| Assay Description
Enzyme inhibition assay using TAFIa. |
US Patent US8609710 (2013)
BindingDB Entry DOI: 10.7270/Q2KW5DPP |
More data for this
Ligand-Target Pair | |
Carboxypeptidase B2
(Homo sapiens (Human)) | BDBM109240
(US8609710, 4)Show SMILES CCC1CC(C1)n1cnc(CC(CCCN)C(O)=O)c1 |(-4.82,4.9,;-3.34,4.5,;-2.94,3.02,;-1.6,2.25,;-2.37,.91,;-3.71,1.68,;-1.98,-.58,;-2.88,-1.82,;-1.98,-3.07,;-.51,-2.59,;.82,-3.36,;2.16,-2.59,;2.16,-1.05,;3.49,-.28,;3.49,1.26,;4.82,2.03,;3.49,-3.36,;3.49,-4.9,;4.82,-2.59,;-.51,-1.05,)| Show InChI InChI=1S/C15H25N3O2/c1-2-11-6-14(7-11)18-9-13(17-10-18)8-12(15(19)20)4-3-5-16/h9-12,14H,2-8,16H2,1H3,(H,19,20) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited
US Patent
| Assay Description
Enzyme inhibition assay using TAFIa. |
US Patent US8609710 (2013)
BindingDB Entry DOI: 10.7270/Q2KW5DPP |
More data for this
Ligand-Target Pair | |
Carboxypeptidase B2
(Homo sapiens (Human)) | BDBM109247
(US8609710, 11)Show SMILES NCCCC(Cc1cn(cn1)[C@@H]1CC2CCC1C2)C(O)=O |r,TLB:8:11:15.14:17| Show InChI InChI=1S/C16H25N3O2/c17-5-1-2-13(16(20)21)8-14-9-19(10-18-14)15-7-11-3-4-12(15)6-11/h9-13,15H,1-8,17H2,(H,20,21)/t11?,12?,13?,15-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited
US Patent
| Assay Description
Enzyme inhibition assay using TAFIa. |
US Patent US8609710 (2013)
BindingDB Entry DOI: 10.7270/Q2KW5DPP |
More data for this
Ligand-Target Pair | |
Carboxypeptidase B2
(Homo sapiens (Human)) | BDBM109245
(US8609710, 9)Show InChI InChI=1S/C16H27N3O2/c1-12-4-2-6-15(8-12)19-10-14(18-11-19)9-13(16(20)21)5-3-7-17/h10-13,15H,2-9,17H2,1H3,(H,20,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited
US Patent
| Assay Description
Enzyme inhibition assay using TAFIa. |
US Patent US8609710 (2013)
BindingDB Entry DOI: 10.7270/Q2KW5DPP |
More data for this
Ligand-Target Pair | |
Carboxypeptidase B2
(Homo sapiens (Human)) | BDBM109261
(US8609710, 37)Show SMILES NCCCC(Cc1cn(cn1)[C@@H]1CC[C@H](O)CC1)C(O)=O |r,wU:14.15,11.11,(4.54,1.79,;3.21,1.02,;3.21,-.52,;1.87,-1.29,;1.87,-2.83,;.54,-3.6,;-.79,-2.83,;-.79,-1.29,;-2.26,-.81,;-3.16,-2.06,;-2.26,-3.3,;-2.66,.68,;-1.57,1.76,;-1.97,3.25,;-3.45,3.65,;-3.85,5.14,;-4.54,2.56,;-4.14,1.07,;3.21,-3.6,;3.21,-5.14,;4.54,-2.83,)| Show InChI InChI=1S/C15H25N3O3/c16-7-1-2-11(15(20)21)8-12-9-18(10-17-12)13-3-5-14(19)6-4-13/h9-11,13-14,19H,1-8,16H2,(H,20,21)/t11?,13-,14+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited
US Patent
| Assay Description
Enzyme inhibition assay using TAFIa. |
US Patent US8609710 (2013)
BindingDB Entry DOI: 10.7270/Q2KW5DPP |
More data for this
Ligand-Target Pair | |
Carboxypeptidase B2
(Homo sapiens (Human)) | BDBM109244
(US8609710, 8)Show SMILES CC1(O)CCC(CC1)n1cnc(CC(CCCN)C(O)=O)c1 |(-4.54,4.74,;-3.45,3.65,;-3.05,5.14,;-1.97,3.25,;-1.57,1.76,;-2.66,.68,;-4.14,1.07,;-4.54,2.56,;-2.26,-.81,;-3.16,-2.06,;-2.26,-3.3,;-.79,-2.83,;.54,-3.6,;1.87,-2.83,;1.87,-1.29,;3.21,-.52,;3.21,1.02,;4.54,1.79,;3.21,-3.6,;3.21,-5.14,;4.54,-2.83,;-.79,-1.29,)| Show InChI InChI=1S/C16H27N3O3/c1-16(22)6-4-14(5-7-16)19-10-13(18-11-19)9-12(15(20)21)3-2-8-17/h10-12,14,22H,2-9,17H2,1H3,(H,20,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited
US Patent
| Assay Description
Enzyme inhibition assay using TAFIa. |
US Patent US8609710 (2013)
BindingDB Entry DOI: 10.7270/Q2KW5DPP |
More data for this
Ligand-Target Pair | |
Carboxypeptidase B2
(Homo sapiens (Human)) | BDBM109246
(US8609710, 10)Show InChI InChI=1S/C16H27N3O2/c17-9-5-6-13(16(20)21)10-14-11-19(12-18-14)15-7-3-1-2-4-8-15/h11-13,15H,1-10,17H2,(H,20,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited
US Patent
| Assay Description
Enzyme inhibition assay using TAFIa. |
US Patent US8609710 (2013)
BindingDB Entry DOI: 10.7270/Q2KW5DPP |
More data for this
Ligand-Target Pair | |
Carboxypeptidase B2
(Homo sapiens (Human)) | BDBM109237
(US8609710, 1)Show InChI InChI=1S/C15H25N3O2/c16-8-4-5-12(15(19)20)9-13-10-18(11-17-13)14-6-2-1-3-7-14/h10-12,14H,1-9,16H2,(H,19,20) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited
US Patent
| Assay Description
Enzyme inhibition assay using TAFIa. |
US Patent US8609710 (2013)
BindingDB Entry DOI: 10.7270/Q2KW5DPP |
More data for this
Ligand-Target Pair | |
Carboxypeptidase B2
(Homo sapiens (Human)) | BDBM109255
(US8609710, 26)Show SMILES C[C@H]1CC[C@@H](CC1)n1cnc(CC(N2CC[C@H](N)C2)C(O)=O)c1 |r,wU:4.7,wD:1.0,16.17,(-3.85,5.14,;-3.45,3.65,;-4.54,2.56,;-4.14,1.07,;-2.66,.68,;-1.57,1.76,;-1.97,3.25,;-2.26,-.81,;-3.16,-2.06,;-2.26,-3.3,;-.79,-2.83,;.54,-3.6,;1.87,-2.83,;1.87,-1.29,;.63,-.38,;1.1,1.08,;2.64,1.08,;3.41,2.42,;3.12,-.38,;3.21,-3.6,;4.54,-2.83,;3.21,-5.14,;-.79,-1.29,)| Show InChI InChI=1S/C17H28N4O2/c1-12-2-4-15(5-3-12)21-10-14(19-11-21)8-16(17(22)23)20-7-6-13(18)9-20/h10-13,15-16H,2-9,18H2,1H3,(H,22,23)/t12-,13-,15-,16?/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited
US Patent
| Assay Description
Enzyme inhibition assay using TAFIa. |
US Patent US8609710 (2013)
BindingDB Entry DOI: 10.7270/Q2KW5DPP |
More data for this
Ligand-Target Pair | |
Carboxypeptidase B2
(Homo sapiens (Human)) | BDBM109242
(US8609710, 6)Show SMILES NCCCC(Cc1cn(cn1)[C@H]1C[C@@H]2C[C@@H]2C1)C(O)=O |r| Show InChI InChI=1S/C15H23N3O2/c16-3-1-2-10(15(19)20)5-13-8-18(9-17-13)14-6-11-4-12(11)7-14/h8-12,14H,1-7,16H2,(H,19,20)/t10?,11-,12+,14- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited
US Patent
| Assay Description
Enzyme inhibition assay using TAFIa. |
US Patent US8609710 (2013)
BindingDB Entry DOI: 10.7270/Q2KW5DPP |
More data for this
Ligand-Target Pair | |
Carboxypeptidase B2
(Homo sapiens (Human)) | BDBM109248
(US8609710, 12)Show SMILES NCCCC(Cc1cn(cn1)[C@H]1CC2CCC1C2)C(O)=O |r,TLB:8:11:15.14:17| Show InChI InChI=1S/C16H25N3O2/c17-5-1-2-13(16(20)21)8-14-9-19(10-18-14)15-7-11-3-4-12(15)6-11/h9-13,15H,1-8,17H2,(H,20,21)/t11?,12?,13?,15-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited
US Patent
| Assay Description
Enzyme inhibition assay using TAFIa. |
US Patent US8609710 (2013)
BindingDB Entry DOI: 10.7270/Q2KW5DPP |
More data for this
Ligand-Target Pair | |
Carboxypeptidase B2
(Homo sapiens (Human)) | BDBM109243
(US8609710, 7)Show SMILES NCCCC(Cc1cn(cn1)[C@H]1CC[C@H](O)CC1)C(O)=O |r,wU:11.11,wD:14.15,(4.54,1.79,;3.21,1.02,;3.21,-.52,;1.87,-1.29,;1.87,-2.83,;.54,-3.6,;-.79,-2.83,;-.79,-1.29,;-2.26,-.81,;-3.16,-2.06,;-2.26,-3.3,;-2.66,.68,;-4.14,1.07,;-4.54,2.56,;-3.45,3.65,;-3.85,5.14,;-1.97,3.25,;-1.57,1.76,;3.21,-3.6,;3.21,-5.14,;4.54,-2.83,)| Show InChI InChI=1S/C15H25N3O3/c16-7-1-2-11(15(20)21)8-12-9-18(10-17-12)13-3-5-14(19)6-4-13/h9-11,13-14,19H,1-8,16H2,(H,20,21)/t11?,13-,14- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited
US Patent
| Assay Description
Enzyme inhibition assay using TAFIa. |
US Patent US8609710 (2013)
BindingDB Entry DOI: 10.7270/Q2KW5DPP |
More data for this
Ligand-Target Pair | |
Carboxypeptidase B2
(Homo sapiens (Human)) | BDBM109257
(US8609710, 34 (2R,4S form))Show SMILES C[C@H](CN)C[C@H](Cc1cn(cn1)[C@H]1CC[C@H](C)CC1)C(O)=O |r,wU:5.5,12.12,1.0,wD:15.16,(4.54,-1.29,;3.21,-.52,;3.21,1.02,;4.54,1.79,;1.87,-1.29,;1.87,-2.83,;.54,-3.6,;-.79,-2.83,;-.79,-1.29,;-2.26,-.81,;-3.16,-2.06,;-2.26,-3.3,;-2.66,.68,;-4.14,1.07,;-4.54,2.56,;-3.45,3.65,;-3.85,5.14,;-1.97,3.25,;-1.57,1.76,;3.21,-3.6,;3.21,-5.14,;4.54,-2.83,)| Show InChI InChI=1S/C17H29N3O2/c1-12-3-5-16(6-4-12)20-10-15(19-11-20)8-14(17(21)22)7-13(2)9-18/h10-14,16H,3-9,18H2,1-2H3,(H,21,22)/t12-,13-,14+,16-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited
US Patent
| Assay Description
Enzyme inhibition assay using TAFIa. |
US Patent US8609710 (2013)
BindingDB Entry DOI: 10.7270/Q2KW5DPP |
More data for this
Ligand-Target Pair | |
Carboxypeptidase B2
(Homo sapiens (Human)) | BDBM109241
(US8609710, 5)Show SMILES CC1CC(C1)n1cnc(CC(CCCN)C(O)=O)c1 |(-3.89,4.7,;-3.5,3.21,;-2.16,2.44,;-2.93,1.11,;-4.27,1.88,;-2.53,-.38,;-3.44,-1.62,;-2.53,-2.87,;-1.07,-2.39,;.26,-3.16,;1.6,-2.39,;1.6,-.85,;2.93,-.08,;2.93,1.46,;4.27,2.23,;2.93,-3.16,;2.93,-4.7,;4.27,-2.39,;-1.07,-.85,)| Show InChI InChI=1S/C14H23N3O2/c1-10-5-13(6-10)17-8-12(16-9-17)7-11(14(18)19)3-2-4-15/h8-11,13H,2-7,15H2,1H3,(H,18,19) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited
US Patent
| Assay Description
Enzyme inhibition assay using TAFIa. |
US Patent US8609710 (2013)
BindingDB Entry DOI: 10.7270/Q2KW5DPP |
More data for this
Ligand-Target Pair | |
Carboxypeptidase B2
(Homo sapiens (Human)) | BDBM109251
(US8609710, 15 (2R form))Show SMILES C[C@H]1CC[C@@H](CC1)n1cnc(C[C@@H](CCCN)C(O)=O)c1 |r,wU:4.7,12.12,wD:1.0,(-3.85,5.14,;-3.45,3.65,;-4.54,2.56,;-4.14,1.07,;-2.66,.68,;-1.57,1.76,;-1.97,3.25,;-2.26,-.81,;-3.16,-2.06,;-2.26,-3.3,;-.79,-2.83,;.54,-3.6,;1.87,-2.83,;1.87,-1.29,;3.21,-.52,;3.21,1.02,;4.54,1.79,;3.21,-3.6,;3.21,-5.14,;4.54,-2.83,;-.79,-1.29,)| Show InChI InChI=1S/C16H27N3O2/c1-12-4-6-15(7-5-12)19-10-14(18-11-19)9-13(16(20)21)3-2-8-17/h10-13,15H,2-9,17H2,1H3,(H,20,21)/t12-,13-,15-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >100 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited
US Patent
| Assay Description
Enzyme inhibition assay using TAFIa. |
US Patent US8609710 (2013)
BindingDB Entry DOI: 10.7270/Q2KW5DPP |
More data for this
Ligand-Target Pair | |
Carboxypeptidase B2
(Homo sapiens (Human)) | BDBM109259
(US8609710, 35 (2R,4R form))Show SMILES C[C@@H](CN)C[C@H](Cc1cn(cn1)[C@H]1CC[C@H](C)CC1)C(O)=O |r,wU:5.5,12.12,wD:15.16,1.0,(4.54,-1.29,;3.21,-.52,;3.21,1.02,;4.54,1.79,;1.87,-1.29,;1.87,-2.83,;.54,-3.6,;-.79,-2.83,;-.79,-1.29,;-2.26,-.81,;-3.16,-2.06,;-2.26,-3.3,;-2.66,.68,;-4.14,1.07,;-4.54,2.56,;-3.45,3.65,;-3.85,5.14,;-1.97,3.25,;-1.57,1.76,;3.21,-3.6,;3.21,-5.14,;4.54,-2.83,)| Show InChI InChI=1S/C17H29N3O2/c1-12-3-5-16(6-4-12)20-10-15(19-11-20)8-14(17(21)22)7-13(2)9-18/h10-14,16H,3-9,18H2,1-2H3,(H,21,22)/t12-,13-,14-,16-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >100 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited
US Patent
| Assay Description
Enzyme inhibition assay using TAFIa. |
US Patent US8609710 (2013)
BindingDB Entry DOI: 10.7270/Q2KW5DPP |
More data for this
Ligand-Target Pair | |
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