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Patent code US8609892

Compile Data Set for Download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Pro-glucagon


(Homo sapiens (Human))		BDBM108253
PNG
(US8609892, 77)
Show SMILES CCCC(Oc1ccc(nc1)-c1ccc(CC(C)C)cc1)c1ccc(cc1)C(=O)NCCC(O)=O
Show InChI InChI=1S/C29H34N2O4/c1-4-5-27(23-10-12-24(13-11-23)29(34)30-17-16-28(32)33)35-25-14-15-26(31-19-25)22-8-6-21(7-9-22)18-20(2)3/h6-15,19-20,27H,4-5,16-18H2,1-3H3,(H,30,34)(H,32,33)
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PC cid
PC sid
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US Patent
 254n/an/an/an/an/an/an/an/a



Eli Lilly and Company

US Patent


Assay Description
The binding assays are carried out using a Scintillation Proximity Assay (Amersham).

US Patent US8609892 (2013)


BindingDB Entry DOI: 10.7270/Q24T6H12
More data for this
Ligand-Target Pair
Pro-glucagon


(Homo sapiens (Human))		BDBM108252
PNG
(US8609892, 25)
Show SMILES CC(C)CC(Sc1ccc(cc1)-c1ccc(C)c(C)c1)c1ccc(cc1)C(=O)NCCC(O)=O
Show InChI InChI=1S/C29H33NO3S/c1-19(2)17-27(23-7-9-24(10-8-23)29(33)30-16-15-28(31)32)34-26-13-11-22(12-14-26)25-6-5-20(3)21(4)18-25/h5-14,18-19,27H,15-17H2,1-4H3,(H,30,33)(H,31,32)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
 265n/an/an/an/an/an/an/an/a



Eli Lilly and Company

US Patent


Assay Description
The binding assays are carried out using a Scintillation Proximity Assay (Amersham).

US Patent US8609892 (2013)


BindingDB Entry DOI: 10.7270/Q24T6H12
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%