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Patent code US8614195

Compile Data Set for Download or QSAR
Found 22 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium/glucose cotransporter 2


(Homo sapiens (Human))		BDBM139462
PNG
(US8614195, 4)
Show SMILES CCc1ccc(cc1Cc1ccc2OCCOc2c1)[C@@H]1O[C@H](COP(=O)(O[Na])O[Na])[C@@H](O)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C23H29O10P.2Na/c1-2-14-4-5-15(11-16(14)9-13-3-6-17-18(10-13)31-8-7-30-17)23-22(26)21(25)20(24)19(33-23)12-32-34(27,28)29;;/h3-6,10-11,19-26H,2,7-9,12H2,1H3,(H2,27,28,29);;/q;2*+1/p-2/t19-,20-,21+,22-,23+;;/m1../s1
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n/an/a 2.40n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The ability of the substances to inhibit the SGLT-2 activity may be demonstrated in a test set-up in which a CHO-K1 cell line (ATCC No. CCL 6 1) or a...

US Patent US8614195 (2013)


BindingDB Entry DOI: 10.7270/Q2XS5T33
More data for this
Ligand-Target Pair
Sodium/glucose cotransporter 2


(Homo sapiens (Human))		BDBM139452
PNG
(US8614195, 2)
Show SMILES CCc1ccc(cc1Cc1ccc2OCCOc2c1)[C@@H]1O[C@H](COC(=O)[C@H](N)C(C)C)[C@@H](O)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C28H37NO8/c1-4-17-6-7-18(13-19(17)11-16-5-8-20-21(12-16)35-10-9-34-20)27-26(32)25(31)24(30)22(37-27)14-36-28(33)23(29)15(2)3/h5-8,12-13,15,22-27,30-32H,4,9-11,14,29H2,1-3H3/t22-,23-,24-,25+,26-,27+/m1/s1
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n/an/a 17.5n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The ability of the substances to inhibit the SGLT-2 activity may be demonstrated in a test set-up in which a CHO-K1 cell line (ATCC No. CCL 6 1) or a...

US Patent US8614195 (2013)


BindingDB Entry DOI: 10.7270/Q2XS5T33
More data for this
Ligand-Target Pair
Sodium/glucose cotransporter 2


(Homo sapiens (Human))		BDBM139463
PNG
(US8614195, 1)
Show SMILES CCc1ccc(cc1Cc1ccc2OCCOc2c1)[C@@H]1O[C@H](COC(=O)[C@H](N)C(C)C)[C@@H](O)[C@H](O)[C@H]1O
Show InChI InChI=1S/C28H37NO8/c1-4-17-6-7-18(13-19(17)11-16-5-8-20-21(12-16)35-10-9-34-20)27-26(32)25(31)24(30)22(37-27)14-36-28(33)23(29)15(2)3/h5-8,12-13,15,22-27,30-32H,4,9-11,14,29H2,1-3H3/t22-,23-,24-,25+,26-,27+/m1/s1
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n/an/a 22.5n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The ability of the substances to inhibit the SGLT-2 activity may be demonstrated in a test set-up in which a CHO-K1 cell line (ATCC No. CCL 6 1) or a...

US Patent US8614195 (2013)


BindingDB Entry DOI: 10.7270/Q2XS5T33
More data for this
Ligand-Target Pair
Sodium/glucose cotransporter 2


(Homo sapiens (Human))		BDBM139456
PNG
(US8614195, 2c)
Show SMILES CCOC(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(CC)c(Cc2ccc3OCCOc3c2)c1 |r|
Show InChI InChI=1S/C26H32O9/c1-3-16-6-7-17(13-18(16)11-15-5-8-19-20(12-15)33-10-9-32-19)25-24(29)23(28)22(27)21(35-25)14-34-26(30)31-4-2/h5-8,12-13,21-25,27-29H,3-4,9-11,14H2,1-2H3/t21-,22-,23+,24-,25+/m1/s1
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n/an/a 27n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The ability of the substances to inhibit the SGLT-2 activity may be demonstrated in a test set-up in which a CHO-K1 cell line (ATCC No. CCL 6 1) or a...

US Patent US8614195 (2013)


BindingDB Entry DOI: 10.7270/Q2XS5T33
More data for this
Ligand-Target Pair
Sodium/glucose cotransporter 1


(Homo sapiens (Human))		BDBM139452
PNG
(US8614195, 2)
Show SMILES CCc1ccc(cc1Cc1ccc2OCCOc2c1)[C@@H]1O[C@H](COC(=O)[C@H](N)C(C)C)[C@@H](O)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C28H37NO8/c1-4-17-6-7-18(13-19(17)11-16-5-8-20-21(12-16)35-10-9-34-20)27-26(32)25(31)24(30)22(37-27)14-36-28(33)23(29)15(2)3/h5-8,12-13,15,22-27,30-32H,4,9-11,14,29H2,1-3H3/t22-,23-,24-,25+,26-,27+/m1/s1
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n/an/a 35n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The ability of the substances to inhibit the SGLT-2 activity may be demonstrated in a test set-up in which a CHO-K1 cell line (ATCC No. CCL 6 1) or a...

US Patent US8614195 (2013)


BindingDB Entry DOI: 10.7270/Q2XS5T33
More data for this
Ligand-Target Pair
Sodium/glucose cotransporter 2


(Homo sapiens (Human))		BDBM139457
PNG
(US8614195, 2e)
Show SMILES CCc1ccc(cc1Cc1ccc2OCCOc2c1)[C@@H]1O[C@H](COC(=O)OC(C)(C)C)[C@@H](O)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C28H36O9/c1-5-17-7-8-18(14-19(17)12-16-6-9-20-21(13-16)34-11-10-33-20)26-25(31)24(30)23(29)22(36-26)15-35-27(32)37-28(2,3)4/h6-9,13-14,22-26,29-31H,5,10-12,15H2,1-4H3/t22-,23-,24+,25-,26+/m1/s1
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n/an/a 89n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The ability of the substances to inhibit the SGLT-2 activity may be demonstrated in a test set-up in which a CHO-K1 cell line (ATCC No. CCL 6 1) or a...

US Patent US8614195 (2013)


BindingDB Entry DOI: 10.7270/Q2XS5T33
More data for this
Ligand-Target Pair
Sodium/glucose cotransporter 1


(Homo sapiens (Human))		BDBM139462
PNG
(US8614195, 4)
Show SMILES CCc1ccc(cc1Cc1ccc2OCCOc2c1)[C@@H]1O[C@H](COP(=O)(O[Na])O[Na])[C@@H](O)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C23H29O10P.2Na/c1-2-14-4-5-15(11-16(14)9-13-3-6-17-18(10-13)31-8-7-30-17)23-22(26)21(25)20(24)19(33-23)12-32-34(27,28)29;;/h3-6,10-11,19-26H,2,7-9,12H2,1H3,(H2,27,28,29);;/q;2*+1/p-2/t19-,20-,21+,22-,23+;;/m1../s1
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n/an/a 89.3n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The ability of the substances to inhibit the SGLT-2 activity may be demonstrated in a test set-up in which a CHO-K1 cell line (ATCC No. CCL 6 1) or a...

US Patent US8614195 (2013)


BindingDB Entry DOI: 10.7270/Q2XS5T33
More data for this
Ligand-Target Pair
Sodium/glucose cotransporter 2


(Homo sapiens (Human))		BDBM139454
PNG
(US8614195, 2a)
Show SMILES CCOC(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(C2CC2)c(Cc2ccc3OCCOc3c2)c1 |r|
Show InChI InChI=1S/C27H32O9/c1-2-32-27(31)35-14-22-23(28)24(29)25(30)26(36-22)17-6-7-19(16-4-5-16)18(13-17)11-15-3-8-20-21(12-15)34-10-9-33-20/h3,6-8,12-13,16,22-26,28-30H,2,4-5,9-11,14H2,1H3/t22-,23-,24+,25-,26+/m1/s1
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n/an/a 97n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The ability of the substances to inhibit the SGLT-2 activity may be demonstrated in a test set-up in which a CHO-K1 cell line (ATCC No. CCL 6 1) or a...

US Patent US8614195 (2013)


BindingDB Entry DOI: 10.7270/Q2XS5T33
More data for this
Ligand-Target Pair
Sodium/glucose cotransporter 2


(Homo sapiens (Human))		BDBM139458
PNG
(US8614195, 2f)
Show SMILES CCc1ccc(cc1Cc1ccc2OCCOc2c1)[C@@H]1O[C@H](COC(=O)OCC2CC3CCC2C3)[C@@H](O)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C32H40O9/c1-2-20-6-7-22(15-23(20)12-19-4-8-25-26(14-19)38-10-9-37-25)31-30(35)29(34)28(33)27(41-31)17-40-32(36)39-16-24-13-18-3-5-21(24)11-18/h4,6-8,14-15,18,21,24,27-31,33-35H,2-3,5,9-13,16-17H2,1H3/t18?,21?,24?,27-,28-,29+,30-,31+/m1/s1
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n/an/a 143n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The ability of the substances to inhibit the SGLT-2 activity may be demonstrated in a test set-up in which a CHO-K1 cell line (ATCC No. CCL 6 1) or a...

US Patent US8614195 (2013)


BindingDB Entry DOI: 10.7270/Q2XS5T33
More data for this
Ligand-Target Pair
Sodium/glucose cotransporter 2


(Homo sapiens (Human))		BDBM139455
PNG
(US8614195, 2b)
Show SMILES CC(C)COC(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(C2CC2)c(Cc2ccc3OCCOc3c2)c1 |r|
Show InChI InChI=1S/C29H36O9/c1-16(2)14-36-29(33)37-15-24-25(30)26(31)27(32)28(38-24)19-6-7-21(18-4-5-18)20(13-19)11-17-3-8-22-23(12-17)35-10-9-34-22/h3,6-8,12-13,16,18,24-28,30-32H,4-5,9-11,14-15H2,1-2H3/t24-,25-,26+,27-,28+/m1/s1
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n/an/a 186n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The ability of the substances to inhibit the SGLT-2 activity may be demonstrated in a test set-up in which a CHO-K1 cell line (ATCC No. CCL 6 1) or a...

US Patent US8614195 (2013)


BindingDB Entry DOI: 10.7270/Q2XS5T33
More data for this
Ligand-Target Pair
Sodium/glucose cotransporter 1


(Homo sapiens (Human))		BDBM139457
PNG
(US8614195, 2e)
Show SMILES CCc1ccc(cc1Cc1ccc2OCCOc2c1)[C@@H]1O[C@H](COC(=O)OC(C)(C)C)[C@@H](O)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C28H36O9/c1-5-17-7-8-18(14-19(17)12-16-6-9-20-21(13-16)34-11-10-33-20)26-25(31)24(30)23(29)22(36-26)15-35-27(32)37-28(2,3)4/h6-9,13-14,22-26,29-31H,5,10-12,15H2,1-4H3/t22-,23-,24+,25-,26+/m1/s1
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n/an/a 188n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The ability of the substances to inhibit the SGLT-2 activity may be demonstrated in a test set-up in which a CHO-K1 cell line (ATCC No. CCL 6 1) or a...

US Patent US8614195 (2013)


BindingDB Entry DOI: 10.7270/Q2XS5T33
More data for this
Ligand-Target Pair
Sodium/glucose cotransporter 1


(Homo sapiens (Human))		BDBM139456
PNG
(US8614195, 2c)
Show SMILES CCOC(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(CC)c(Cc2ccc3OCCOc3c2)c1 |r|
Show InChI InChI=1S/C26H32O9/c1-3-16-6-7-17(13-18(16)11-15-5-8-19-20(12-15)33-10-9-32-19)25-24(29)23(28)22(27)21(35-25)14-34-26(30)31-4-2/h5-8,12-13,21-25,27-29H,3-4,9-11,14H2,1-2H3/t21-,22-,23+,24-,25+/m1/s1
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n/an/a 197n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The ability of the substances to inhibit the SGLT-2 activity may be demonstrated in a test set-up in which a CHO-K1 cell line (ATCC No. CCL 6 1) or a...

US Patent US8614195 (2013)


BindingDB Entry DOI: 10.7270/Q2XS5T33
More data for this
Ligand-Target Pair
Sodium/glucose cotransporter 1


(Homo sapiens (Human))		BDBM139454
PNG
(US8614195, 2a)
Show SMILES CCOC(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(C2CC2)c(Cc2ccc3OCCOc3c2)c1 |r|
Show InChI InChI=1S/C27H32O9/c1-2-32-27(31)35-14-22-23(28)24(29)25(30)26(36-22)17-6-7-19(16-4-5-16)18(13-17)11-15-3-8-20-21(12-15)34-10-9-33-20/h3,6-8,12-13,16,22-26,28-30H,2,4-5,9-11,14H2,1H3/t22-,23-,24+,25-,26+/m1/s1
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n/an/a 308n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The ability of the substances to inhibit the SGLT-2 activity may be demonstrated in a test set-up in which a CHO-K1 cell line (ATCC No. CCL 6 1) or a...

US Patent US8614195 (2013)


BindingDB Entry DOI: 10.7270/Q2XS5T33
More data for this
Ligand-Target Pair
Sodium/glucose cotransporter 1


(Homo sapiens (Human))		BDBM139455
PNG
(US8614195, 2b)
Show SMILES CC(C)COC(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(C2CC2)c(Cc2ccc3OCCOc3c2)c1 |r|
Show InChI InChI=1S/C29H36O9/c1-16(2)14-36-29(33)37-15-24-25(30)26(31)27(32)28(38-24)19-6-7-21(18-4-5-18)20(13-19)11-17-3-8-22-23(12-17)35-10-9-34-22/h3,6-8,12-13,16,18,24-28,30-32H,4-5,9-11,14-15H2,1-2H3/t24-,25-,26+,27-,28+/m1/s1
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n/an/a 338n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The ability of the substances to inhibit the SGLT-2 activity may be demonstrated in a test set-up in which a CHO-K1 cell line (ATCC No. CCL 6 1) or a...

US Patent US8614195 (2013)


BindingDB Entry DOI: 10.7270/Q2XS5T33
More data for this
Ligand-Target Pair
Sodium/glucose cotransporter 1


(Homo sapiens (Human))		BDBM139463
PNG
(US8614195, 1)
Show SMILES CCc1ccc(cc1Cc1ccc2OCCOc2c1)[C@@H]1O[C@H](COC(=O)[C@H](N)C(C)C)[C@@H](O)[C@H](O)[C@H]1O
Show InChI InChI=1S/C28H37NO8/c1-4-17-6-7-18(13-19(17)11-16-5-8-20-21(12-16)35-10-9-34-20)27-26(32)25(31)24(30)22(37-27)14-36-28(33)23(29)15(2)3/h5-8,12-13,15,22-27,30-32H,4,9-11,14,29H2,1-3H3/t22-,23-,24-,25+,26-,27+/m1/s1
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n/an/a 409n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The ability of the substances to inhibit the SGLT-2 activity may be demonstrated in a test set-up in which a CHO-K1 cell line (ATCC No. CCL 6 1) or a...

US Patent US8614195 (2013)


BindingDB Entry DOI: 10.7270/Q2XS5T33
More data for this
Ligand-Target Pair
Sodium/glucose cotransporter 2


(Homo sapiens (Human))		BDBM139459
PNG
(US8614195, 2g)
Show SMILES CCc1ccc(cc1Cc1ccc2OCCOc2c1)[C@@H]1O[C@H](COC(=O)OC(C)c2ccccc2)[C@@H](O)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C32H36O9/c1-3-21-10-11-23(17-24(21)15-20-9-12-25-26(16-20)38-14-13-37-25)31-30(35)29(34)28(33)27(41-31)18-39-32(36)40-19(2)22-7-5-4-6-8-22/h4-12,16-17,19,27-31,33-35H,3,13-15,18H2,1-2H3/t19?,27-,28-,29+,30-,31+/m1/s1
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n/an/a 567n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The ability of the substances to inhibit the SGLT-2 activity may be demonstrated in a test set-up in which a CHO-K1 cell line (ATCC No. CCL 6 1) or a...

US Patent US8614195 (2013)


BindingDB Entry DOI: 10.7270/Q2XS5T33
More data for this
Ligand-Target Pair
Sodium/glucose cotransporter 1


(Homo sapiens (Human))		BDBM139460
PNG
(US8614195, 3)
Show SMILES CCOP(=O)(OCC)OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(CC)c(Cc2ccc3OCCOc3c2)c1 |r|
Show InChI InChI=1S/C27H37O10P/c1-4-18-8-9-19(15-20(18)13-17-7-10-21-22(14-17)33-12-11-32-21)27-26(30)25(29)24(28)23(37-27)16-36-38(31,34-5-2)35-6-3/h7-10,14-15,23-30H,4-6,11-13,16H2,1-3H3/t23-,24-,25+,26-,27+/m1/s1
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n/an/a 814n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The ability of the substances to inhibit the SGLT-2 activity may be demonstrated in a test set-up in which a CHO-K1 cell line (ATCC No. CCL 6 1) or a...

US Patent US8614195 (2013)


BindingDB Entry DOI: 10.7270/Q2XS5T33
More data for this
Ligand-Target Pair
Sodium/glucose cotransporter 2


(Homo sapiens (Human))		BDBM139460
PNG
(US8614195, 3)
Show SMILES CCOP(=O)(OCC)OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(CC)c(Cc2ccc3OCCOc3c2)c1 |r|
Show InChI InChI=1S/C27H37O10P/c1-4-18-8-9-19(15-20(18)13-17-7-10-21-22(14-17)33-12-11-32-21)27-26(30)25(29)24(28)23(37-27)16-36-38(31,34-5-2)35-6-3/h7-10,14-15,23-30H,4-6,11-13,16H2,1-3H3/t23-,24-,25+,26-,27+/m1/s1
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n/an/a>1.00E+3n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The ability of the substances to inhibit the SGLT-2 activity may be demonstrated in a test set-up in which a CHO-K1 cell line (ATCC No. CCL 6 1) or a...

US Patent US8614195 (2013)


BindingDB Entry DOI: 10.7270/Q2XS5T33
More data for this
Ligand-Target Pair
Sodium/glucose cotransporter 1


(Homo sapiens (Human))		BDBM139459
PNG
(US8614195, 2g)
Show SMILES CCc1ccc(cc1Cc1ccc2OCCOc2c1)[C@@H]1O[C@H](COC(=O)OC(C)c2ccccc2)[C@@H](O)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C32H36O9/c1-3-21-10-11-23(17-24(21)15-20-9-12-25-26(16-20)38-14-13-37-25)31-30(35)29(34)28(33)27(41-31)18-39-32(36)40-19(2)22-7-5-4-6-8-22/h4-12,16-17,19,27-31,33-35H,3,13-15,18H2,1-2H3/t19?,27-,28-,29+,30-,31+/m1/s1
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n/an/a 1.00E+3n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The ability of the substances to inhibit the SGLT-2 activity may be demonstrated in a test set-up in which a CHO-K1 cell line (ATCC No. CCL 6 1) or a...

US Patent US8614195 (2013)


BindingDB Entry DOI: 10.7270/Q2XS5T33
More data for this
Ligand-Target Pair
Sodium/glucose cotransporter 2


(Homo sapiens (Human))		BDBM139461
PNG
(US8614195, 3a)
Show SMILES CCOP(=O)(OCC)OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(C2CC2)c(Cc2ccc3OCCOc3c2)c1 |r|
Show InChI InChI=1S/C28H37O10P/c1-3-35-39(32,36-4-2)37-16-24-25(29)26(30)27(31)28(38-24)19-8-9-21(18-6-7-18)20(15-19)13-17-5-10-22-23(14-17)34-12-11-33-22/h5,8-10,14-15,18,24-31H,3-4,6-7,11-13,16H2,1-2H3/t24-,25-,26+,27-,28+/m1/s1
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n/an/a>1.00E+3n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The ability of the substances to inhibit the SGLT-2 activity may be demonstrated in a test set-up in which a CHO-K1 cell line (ATCC No. CCL 6 1) or a...

US Patent US8614195 (2013)


BindingDB Entry DOI: 10.7270/Q2XS5T33
More data for this
Ligand-Target Pair
Sodium/glucose cotransporter 1


(Homo sapiens (Human))		BDBM139458
PNG
(US8614195, 2f)
Show SMILES CCc1ccc(cc1Cc1ccc2OCCOc2c1)[C@@H]1O[C@H](COC(=O)OCC2CC3CCC2C3)[C@@H](O)[C@H](O)[C@H]1O |r|
Show InChI InChI=1S/C32H40O9/c1-2-20-6-7-22(15-23(20)12-19-4-8-25-26(14-19)38-10-9-37-25)31-30(35)29(34)28(33)27(41-31)17-40-32(36)39-16-24-13-18-3-5-21(24)11-18/h4,6-8,14-15,18,21,24,27-31,33-35H,2-3,5,9-13,16-17H2,1H3/t18?,21?,24?,27-,28-,29+,30-,31+/m1/s1
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n/an/a 3.44E+3n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The ability of the substances to inhibit the SGLT-2 activity may be demonstrated in a test set-up in which a CHO-K1 cell line (ATCC No. CCL 6 1) or a...

US Patent US8614195 (2013)


BindingDB Entry DOI: 10.7270/Q2XS5T33
More data for this
Ligand-Target Pair
Sodium/glucose cotransporter 1


(Homo sapiens (Human))		BDBM139461
PNG
(US8614195, 3a)
Show SMILES CCOP(=O)(OCC)OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(C2CC2)c(Cc2ccc3OCCOc3c2)c1 |r|
Show InChI InChI=1S/C28H37O10P/c1-3-35-39(32,36-4-2)37-16-24-25(29)26(30)27(31)28(38-24)19-8-9-21(18-6-7-18)20(15-19)13-17-5-10-22-23(14-17)34-12-11-33-22/h5,8-10,14-15,18,24-31H,3-4,6-7,11-13,16H2,1-2H3/t24-,25-,26+,27-,28+/m1/s1
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n/an/a 5.65E+3n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
The ability of the substances to inhibit the SGLT-2 activity may be demonstrated in a test set-up in which a CHO-K1 cell line (ATCC No. CCL 6 1) or a...

US Patent US8614195 (2013)


BindingDB Entry DOI: 10.7270/Q2XS5T33
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%