Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Macrophage migration inhibitory factor (Mus musculus (Mouse)) | BDBM50186443 (CHEMBL210592 | US8618147, 16 | neopentyl 2-(3-(4-h...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | 7.2 | 25 |
The Feinstein Institute for Medical Research US Patent | Assay Description MIF tautomerase activity was measured by UV-Visible recording spectrophotometry (SHIMADZU, UV1600U). A fresh stock solution of L-dopachrome methyl es... | US Patent US8618147 (2013) BindingDB Entry DOI: 10.7270/Q23R0RHZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Mus musculus (Mouse)) | BDBM50186445 (CHEMBL209401 | US8618147, 14 | cyclohexyl 2-(3-(4-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | 7.2 | 25 |
The Feinstein Institute for Medical Research US Patent | Assay Description MIF tautomerase activity was measured by UV-Visible recording spectrophotometry (SHIMADZU, UV1600U). A fresh stock solution of L-dopachrome methyl es... | US Patent US8618147 (2013) BindingDB Entry DOI: 10.7270/Q23R0RHZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Mus musculus (Mouse)) | BDBM50186429 (CHEMBL210755 | US8618147, 13 | butyl 2-(3-(4-hydro...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | 7.2 | 25 |
The Feinstein Institute for Medical Research US Patent | Assay Description MIF tautomerase activity was measured by UV-Visible recording spectrophotometry (SHIMADZU, UV1600U). A fresh stock solution of L-dopachrome methyl es... | US Patent US8618147 (2013) BindingDB Entry DOI: 10.7270/Q23R0RHZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Mus musculus (Mouse)) | BDBM50186439 (CHEMBL208659 | US8618147, 11 | propyl 2-(3-(4-hydr...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | 7.2 | 25 |
The Feinstein Institute for Medical Research US Patent | Assay Description MIF tautomerase activity was measured by UV-Visible recording spectrophotometry (SHIMADZU, UV1600U). A fresh stock solution of L-dopachrome methyl es... | US Patent US8618147 (2013) BindingDB Entry DOI: 10.7270/Q23R0RHZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Mus musculus (Mouse)) | BDBM50186430 (CHEMBL377184 | US8618147, 15 | cyclohexylmethyl 2-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | 7.2 | 25 |
The Feinstein Institute for Medical Research US Patent | Assay Description MIF tautomerase activity was measured by UV-Visible recording spectrophotometry (SHIMADZU, UV1600U). A fresh stock solution of L-dopachrome methyl es... | US Patent US8618147 (2013) BindingDB Entry DOI: 10.7270/Q23R0RHZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Mus musculus (Mouse)) | BDBM50186425 (CHEMBL208716 | US8618147, 12 | isopropyl 2-(3-(4-h...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | 7.2 | 25 |
The Feinstein Institute for Medical Research US Patent | Assay Description MIF tautomerase activity was measured by UV-Visible recording spectrophotometry (SHIMADZU, UV1600U). A fresh stock solution of L-dopachrome methyl es... | US Patent US8618147 (2013) BindingDB Entry DOI: 10.7270/Q23R0RHZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Mus musculus (Mouse)) | BDBM50186431 (CHEMBL210529 | US8618147, 8 | tert-butyl 4-(2-(3-(...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 8.50E+3 | n/a | n/a | n/a | n/a | 7.2 | 25 |
The Feinstein Institute for Medical Research US Patent | Assay Description MIF tautomerase activity was measured by UV-Visible recording spectrophotometry (SHIMADZU, UV1600U). A fresh stock solution of L-dopachrome methyl es... | US Patent US8618147 (2013) BindingDB Entry DOI: 10.7270/Q23R0RHZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Mus musculus (Mouse)) | BDBM111576 (US8618147, 3) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 8.50E+3 | n/a | n/a | n/a | n/a | 7.2 | 25 |
The Feinstein Institute for Medical Research US Patent | Assay Description MIF tautomerase activity was measured by UV-Visible recording spectrophotometry (SHIMADZU, UV1600U). A fresh stock solution of L-dopachrome methyl es... | US Patent US8618147 (2013) BindingDB Entry DOI: 10.7270/Q23R0RHZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Mus musculus (Mouse)) | BDBM50186424 (CHEMBL377038 | US8618147, 2 | phenyl 2-(3-(4-hydro...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | 7.2 | 25 |
The Feinstein Institute for Medical Research US Patent | Assay Description MIF tautomerase activity was measured by UV-Visible recording spectrophotometry (SHIMADZU, UV1600U). A fresh stock solution of L-dopachrome methyl es... | US Patent US8618147 (2013) BindingDB Entry DOI: 10.7270/Q23R0RHZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Mus musculus (Mouse)) | BDBM50186432 (4-tert-butylphenyl 2-(3-(4-hydroxyphenyl)-4,5-dihy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | 7.2 | 25 |
The Feinstein Institute for Medical Research US Patent | Assay Description MIF tautomerase activity was measured by UV-Visible recording spectrophotometry (SHIMADZU, UV1600U). A fresh stock solution of L-dopachrome methyl es... | US Patent US8618147 (2013) BindingDB Entry DOI: 10.7270/Q23R0RHZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Mus musculus (Mouse)) | BDBM50186426 (CHEMBL210858 | US10336721, ISO-1 | US10968198, ISO...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PDB US Patent | n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | 7.2 | 25 |
The Feinstein Institute for Medical Research US Patent | Assay Description MIF tautomerase activity was measured by UV-Visible recording spectrophotometry (SHIMADZU, UV1600U). A fresh stock solution of L-dopachrome methyl es... | US Patent US8618147 (2013) BindingDB Entry DOI: 10.7270/Q23R0RHZ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Macrophage migration inhibitory factor (Mus musculus (Mouse)) | BDBM50186442 (CHEMBL208658 | US8618147, 10 | ethyl 2-(3-(4-hydro...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | 7.2 | 25 |
The Feinstein Institute for Medical Research US Patent | Assay Description MIF tautomerase activity was measured by UV-Visible recording spectrophotometry (SHIMADZU, UV1600U). A fresh stock solution of L-dopachrome methyl es... | US Patent US8618147 (2013) BindingDB Entry DOI: 10.7270/Q23R0RHZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Mus musculus (Mouse)) | BDBM50186435 (CHEMBL378265 | US8618147, 5 | mesityl 2-(3-(4-hydr...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | 7.2 | 25 |
The Feinstein Institute for Medical Research US Patent | Assay Description MIF tautomerase activity was measured by UV-Visible recording spectrophotometry (SHIMADZU, UV1600U). A fresh stock solution of L-dopachrome methyl es... | US Patent US8618147 (2013) BindingDB Entry DOI: 10.7270/Q23R0RHZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Mus musculus (Mouse)) | BDBM50186441 (CHEMBL210426 | N-cyclohexyl-2-(3-(4-hydroxyphenyl)...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 2.40E+4 | n/a | n/a | n/a | n/a | 7.2 | 25 |
The Feinstein Institute for Medical Research US Patent | Assay Description MIF tautomerase activity was measured by UV-Visible recording spectrophotometry (SHIMADZU, UV1600U). A fresh stock solution of L-dopachrome methyl es... | US Patent US8618147 (2013) BindingDB Entry DOI: 10.7270/Q23R0RHZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Mus musculus (Mouse)) | BDBM50186428 (2-(3-(4-hydroxyphenyl)-4,5-dihydroisoxazol-5-yl)-N...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.60E+4 | n/a | n/a | n/a | n/a | 7.2 | 25 |
The Feinstein Institute for Medical Research US Patent | Assay Description MIF tautomerase activity was measured by UV-Visible recording spectrophotometry (SHIMADZU, UV1600U). A fresh stock solution of L-dopachrome methyl es... | US Patent US8618147 (2013) BindingDB Entry DOI: 10.7270/Q23R0RHZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Mus musculus (Mouse)) | BDBM50186437 (CHEMBL377311 | N-(4-aminobutyl)-2-(3-(4-hydroxyphe...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | 7.2 | 25 |
The Feinstein Institute for Medical Research US Patent | Assay Description MIF tautomerase activity was measured by UV-Visible recording spectrophotometry (SHIMADZU, UV1600U). A fresh stock solution of L-dopachrome methyl es... | US Patent US8618147 (2013) BindingDB Entry DOI: 10.7270/Q23R0RHZ | |||||||||||
More data for this Ligand-Target Pair |