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Patent code US8618158

Compile Data Set for Download or QSAR
Found 80 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111568
PNG
(US8618158, NCL-00016149)
Show SMILES OC(=O)CCC(=O)OCC1(COC2(N(Cc3ccc(cc3)[N+]([O-])=O)C(=O)c3cccc(Cl)c23)c2ccc(Cl)cc2)CC1 |w:12.11|
Show InChI InChI=1S/C30H26Cl2N2O8/c31-21-8-6-20(7-9-21)30(42-18-29(14-15-29)17-41-26(37)13-12-25(35)36)27-23(2-1-3-24(27)32)28(38)33(30)16-19-4-10-22(11-5-19)34(39)40/h1-11H,12-18H2,(H,35,36)
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n/an/a 19n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111547
PNG
(US8618158, NCL-00013774 | US8618158, NCL-00013775 ...)
Show SMILES OCC1(COC2(N(Cc3ccc(cc3)[N+]([O-])=O)C(=O)c3cccc(Cl)c23)c2ccc(Cl)cc2)CC1
Show InChI InChI=1S/C26H22Cl2N2O5/c27-19-8-6-18(7-9-19)26(35-16-25(15-31)12-13-25)23-21(2-1-3-22(23)28)24(32)29(26)14-17-4-10-20(11-5-17)30(33)34/h1-11,31H,12-16H2
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n/an/a 40n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111569
PNG
(US8618158, NCL-00016659)
Show SMILES OC(=O)CCC(=O)OCC1(COC2(N(Cc3ccc(cc3)C#N)C(=O)c3cccc(Cl)c23)c2ccc(Cl)cc2)CC1 |w:12.11|
Show InChI InChI=1S/C31H26Cl2N2O6/c32-23-10-8-22(9-11-23)31(41-19-30(14-15-30)18-40-27(38)13-12-26(36)37)28-24(2-1-3-25(28)33)29(39)35(31)17-21-6-4-20(16-34)5-7-21/h1-11H,12-15,17-19H2,(H,36,37)
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n/an/a 102n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111570
PNG
(US8618158, NCL-00016653)
Show SMILES OC(=O)CCC(=O)OCC1(COC2(N(Cc3ccc(Br)cc3)C(=O)c3cccc(Cl)c23)c2ccc(Cl)cc2)CC1 |w:12.11|
Show InChI InChI=1S/C30H26BrCl2NO6/c31-21-8-4-19(5-9-21)16-34-28(38)23-2-1-3-24(33)27(23)30(34,20-6-10-22(32)11-7-20)40-18-29(14-15-29)17-39-26(37)13-12-25(35)36/h1-11H,12-18H2,(H,35,36)
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n/an/a 102n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111547
PNG
(US8618158, NCL-00013774 | US8618158, NCL-00013775 ...)
Show SMILES OCC1(COC2(N(Cc3ccc(cc3)[N+]([O-])=O)C(=O)c3cccc(Cl)c23)c2ccc(Cl)cc2)CC1
Show InChI InChI=1S/C26H22Cl2N2O5/c27-19-8-6-18(7-9-19)26(35-16-25(15-31)12-13-25)23-21(2-1-3-22(23)28)24(32)29(26)14-17-4-10-20(11-5-17)30(33)34/h1-11,31H,12-16H2
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n/an/a 143n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111532
PNG
(US8618158, NU8399)
Show SMILES CC(C)(C)c1ccc2c(c1)C(=O)N(Cc1ccc(cc1)[N+]([O-])=O)C2(OCC1(CO)CC1)c1ccc(Cl)cc1
Show InChI InChI=1S/C30H31ClN2O5/c1-28(2,3)22-8-13-26-25(16-22)27(35)32(17-20-4-11-24(12-5-20)33(36)37)30(26,21-6-9-23(31)10-7-21)38-19-29(18-34)14-15-29/h4-13,16,34H,14-15,17-19H2,1-3H3
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n/an/a 152n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111540
PNG
(US8618158, NCL-00010493)
Show SMILES OCC1(COC2(N(Cc3ccc(Br)cc3)C(=O)c3cccc(Cl)c23)c2ccc(Cl)cc2)CC1
Show InChI InChI=1S/C26H22BrCl2NO3/c27-19-8-4-17(5-9-19)14-30-24(32)21-2-1-3-22(29)23(21)26(30,18-6-10-20(28)11-7-18)33-16-25(15-31)12-13-25/h1-11,31H,12-16H2
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n/an/a 169n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111539
PNG
(US8618158, NCL-00010492)
Show SMILES OCC1(COC2(N(Cc3ccc(cc3)C#N)C(=O)c3cccc(Cl)c23)c2ccc(Cl)cc2)CC1
Show InChI InChI=1S/C27H22Cl2N2O3/c28-21-10-8-20(9-11-21)27(34-17-26(16-32)12-13-26)24-22(2-1-3-23(24)29)25(33)31(27)15-19-6-4-18(14-30)5-7-19/h1-11,32H,12-13,15-17H2
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n/an/a 185n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111546
PNG
(US8618158, NU8405)
Show SMILES Cc1cccc2C(=O)N(Cc3ccc(cc3)[N+]([O-])=O)C(OCC3(CO)CC3)(c12)c1ccc(Cl)cc1
Show InChI InChI=1S/C27H25ClN2O5/c1-18-3-2-4-23-24(18)27(20-7-9-21(28)10-8-20,35-17-26(16-31)13-14-26)29(25(23)32)15-19-5-11-22(12-6-19)30(33)34/h2-12,31H,13-17H2,1H3
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n/an/a 274n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111542
PNG
(US8618158, NCL-00010495)
Show SMILES OCC1(COC2(N(Cc3ccc(cc3)[N+]([O-])=O)C(=O)c3ccc(F)cc23)c2ccc(Cl)cc2)CC1
Show InChI InChI=1S/C26H22ClFN2O5/c27-19-5-3-18(4-6-19)26(35-16-25(15-31)11-12-25)23-13-20(28)7-10-22(23)24(32)29(26)14-17-1-8-21(9-2-17)30(33)34/h1-10,13,31H,11-12,14-16H2
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n/an/a 295n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111513
PNG
(US8618158, NU8354)
Show SMILES OCC1(COC2(N(Cc3ccc(cc3)[N+]([O-])=O)C(=O)c3ccccc23)c2ccc(Cl)cc2)CC1 |w:5.4|
Show InChI InChI=1S/C26H23ClN2O5/c27-20-9-7-19(8-10-20)26(34-17-25(16-30)13-14-25)23-4-2-1-3-22(23)24(31)28(26)15-18-5-11-21(12-6-18)29(32)33/h1-12,30H,13-17H2
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n/an/a 298n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111518
PNG
(US8618158, NU8361)
Show SMILES O[C@H]1CC[C@H](OC2(N(Cc3ccc(cc3)[N+]([O-])=O)C(=O)c3ccccc23)c2ccc(Cl)cc2)C=C1 |r,w:6.5,c:37|
Show InChI InChI=1S/C27H23ClN2O5/c28-20-9-7-19(8-10-20)27(35-23-15-13-22(31)14-16-23)25-4-2-1-3-24(25)26(32)29(27)17-18-5-11-21(12-6-18)30(33)34/h1-13,15,22-23,31H,14,16-17H2/t22-,23-,27?/m1/s1
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n/an/a 306n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111524
PNG
(US8618158, NU8391)
Show SMILES OCC1(COC2(N(Cc3ccc(cc3)[N+]([O-])=O)C(=O)c3ccccc23)c2ccc(Br)cc2)CC1 |w:5.4|
Show InChI InChI=1S/C26H23BrN2O5/c27-20-9-7-19(8-10-20)26(34-17-25(16-30)13-14-25)23-4-2-1-3-22(23)24(31)28(26)15-18-5-11-21(12-6-18)29(32)33/h1-12,30H,13-17H2
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n/an/a 368n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111511
PNG
(US8618158, NU8352)
Show SMILES O[C@H]1CCC[C@H](CCC1)OC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2ccccc12)c1ccc(Cl)cc1 |r,w:10.10|
Show InChI InChI=1S/C29H29ClN2O5/c30-22-15-13-21(14-16-22)29(37-25-7-3-5-24(33)6-4-8-25)27-10-2-1-9-26(27)28(34)31(29)19-20-11-17-23(18-12-20)32(35)36/h1-2,9-18,24-25,33H,3-8,19H2/t24-,25+,29?
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n/an/a 375n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111517
PNG
(US8618158, NU8360)
Show SMILES OC1CC[C@@H](CC1)OC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2ccccc12)c1ccc(Cl)cc1 |r,w:8.8,1.0,wU:4.7,(-4.44,7.19,;-4.04,5.7,;-5.13,4.61,;-4.73,3.12,;-3.25,2.72,;-2.16,3.81,;-2.56,5.3,;-2.85,1.24,;-2.08,-.1,;-1.17,-1.34,;.37,-1.34,;1.46,-2.43,;1.06,-3.92,;2.15,-5.01,;3.63,-4.61,;4.03,-3.12,;2.94,-2.03,;4.72,-5.7,;4.32,-7.19,;6.21,-5.3,;-2.08,-2.59,;-1.31,-3.92,;-3.54,-2.11,;-4.88,-2.88,;-6.21,-2.11,;-6.21,-.57,;-4.88,.2,;-3.54,-.57,;-.99,.99,;.5,.59,;1.59,1.68,;1.19,3.17,;2.28,4.26,;-.3,3.57,;-1.39,2.48,)|
Show InChI InChI=1S/C27H25ClN2O5/c28-20-9-7-19(8-10-20)27(35-23-15-13-22(31)14-16-23)25-4-2-1-3-24(25)26(32)29(27)17-18-5-11-21(12-6-18)30(33)34/h1-12,22-23,31H,13-17H2/t22?,23-,27?
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n/an/a 388n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111512
PNG
(US8618158, NU8353)
Show SMILES CC(C)(CO)COC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2ccccc12)c1ccc(Cl)cc1 |w:7.6|
Show InChI InChI=1S/C26H25ClN2O5/c1-25(2,16-30)17-34-26(19-9-11-20(27)12-10-19)23-6-4-3-5-22(23)24(31)28(26)15-18-7-13-21(14-8-18)29(32)33/h3-14,30H,15-17H2,1-2H3
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n/an/a 395n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111509
PNG
(US8618158, NU8350)
Show SMILES OC\C=C/COC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2ccccc12)c1ccc(Cl)cc1 |w:6.5|
Show InChI InChI=1S/C25H21ClN2O5/c26-20-11-9-19(10-12-20)25(33-16-4-3-15-29)23-6-2-1-5-22(23)24(30)27(25)17-18-7-13-21(14-8-18)28(31)32/h1-14,29H,15-17H2/b4-3-
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n/an/a 402n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111510
PNG
(US8618158, NU8351)
Show SMILES OCC=CCOC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2ccccc12)c1ccc(Cl)cc1 |w:6.5,2.1|
Show InChI InChI=1S/C25H21ClN2O5/c26-20-11-9-19(10-12-20)25(33-16-4-3-15-29)23-6-2-1-5-22(23)24(30)27(25)17-18-7-13-21(14-8-18)28(31)32/h1-14,29H,15-17H2
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n/an/a 405n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111545
PNG
(US8618158, NU8401)
Show SMILES Cc1ccc2C(=O)N(Cc3ccc(cc3)[N+]([O-])=O)C(OCC3(CO)CC3)(c2c1)c1ccc(Cl)cc1
Show InChI InChI=1S/C27H25ClN2O5/c1-18-2-11-23-24(14-18)27(20-5-7-21(28)8-6-20,35-17-26(16-31)12-13-26)29(25(23)32)15-19-3-9-22(10-4-19)30(33)34/h2-11,14,31H,12-13,15-17H2,1H3
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n/an/a 492n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111531
PNG
(US8618158, NU8398)
Show SMILES OC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2cccc(Cl)c12)c1ccc(Cl)cc1
Show InChI InChI=1S/C21H14Cl2N2O4/c22-15-8-6-14(7-9-15)21(27)19-17(2-1-3-18(19)23)20(26)24(21)12-13-4-10-16(11-5-13)25(28)29/h1-11,27H,12H2
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n/an/a 510n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111554
PNG
(US8618158, NU8398)
Show SMILES OC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2cccc(Cl)c12)c1ccc(Cl)cc1 |w:1.0|
Show InChI InChI=1S/C21H14Cl2N2O4/c22-15-8-6-14(7-9-15)21(27)19-17(2-1-3-18(19)23)20(26)24(21)12-13-4-10-16(11-5-13)25(28)29/h1-11,27H,12H2
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n/an/a 510n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111516
PNG
(US8618158, NU8359)
Show SMILES OC[C@H]1CCCC[C@H]1COC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2ccccc12)c1ccc(Cl)cc1 |r,w:10.10|
Show InChI InChI=1S/C29H29ClN2O5/c30-24-13-11-23(12-14-24)29(37-19-22-6-2-1-5-21(22)18-33)27-8-4-3-7-26(27)28(34)31(29)17-20-9-15-25(16-10-20)32(35)36/h3-4,7-16,21-22,33H,1-2,5-6,17-19H2/t21-,22+,29?/m1/s1
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n/an/a 569n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111523
PNG
(US8618158, NU8390)
Show SMILES OCCCCOC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2ccccc12)c1ccc(Br)cc1 |w:6.5|
Show InChI InChI=1S/C25H23BrN2O5/c26-20-11-9-19(10-12-20)25(33-16-4-3-15-29)23-6-2-1-5-22(23)24(30)27(25)17-18-7-13-21(14-8-18)28(31)32/h1-2,5-14,29H,3-4,15-17H2
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n/an/a 570n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111515
PNG
(US8618158, NU8358)
Show SMILES OC[C@H]1CC[C@H](COC2(N(Cc3ccc(cc3)[N+]([O-])=O)C(=O)c3ccccc23)c2ccc(Cl)cc2)CC1 |r,w:8.7,wU:5.5,wD:2.1,(-5.52,8.06,;-4.18,7.29,;-4.18,5.75,;-5.52,4.98,;-5.52,3.44,;-4.18,2.67,;-4.18,1.13,;-2.85,.36,;-2.08,-.97,;-1.17,-2.22,;.37,-2.22,;1.46,-3.31,;1.06,-4.79,;2.15,-5.88,;3.63,-5.49,;4.03,-4,;2.94,-2.91,;4.72,-6.57,;4.32,-8.06,;6.21,-6.18,;-2.08,-3.46,;-1.31,-4.8,;-3.54,-2.99,;-4.88,-3.76,;-6.21,-2.99,;-6.21,-1.45,;-4.88,-.68,;-3.54,-1.45,;-.99,.12,;.5,-.28,;1.59,.81,;1.19,2.29,;2.28,3.38,;-.3,2.69,;-1.39,1.6,;-2.85,3.44,;-2.85,4.98,)|
Show InChI InChI=1S/C29H29ClN2O5/c30-24-13-11-23(12-14-24)29(37-19-22-7-5-21(18-33)6-8-22)27-4-2-1-3-26(27)28(34)31(29)17-20-9-15-25(16-10-20)32(35)36/h1-4,9-16,21-22,33H,5-8,17-19H2/t21-,22-,29?
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n/an/a 582n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111514
PNG
(US8618158, NU8357)
Show SMILES OCC#CCOC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2ccccc12)c1ccc(Cl)cc1 |w:6.5|
Show InChI InChI=1S/C25H19ClN2O5/c26-20-11-9-19(10-12-20)25(33-16-4-3-15-29)23-6-2-1-5-22(23)24(30)27(25)17-18-7-13-21(14-8-18)28(31)32/h1-2,5-14,29H,15-17H2
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n/an/a 656n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111573
PNG
(US8618158, NCL-00016895)
Show SMILES OCC(=C)COC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2ccccc12)c1ccc(Cl)cc1 |w:6.5|
Show InChI InChI=1S/C25H21ClN2O5/c1-17(15-29)16-33-25(19-8-10-20(26)11-9-19)23-5-3-2-4-22(23)24(30)27(25)14-18-6-12-21(13-7-18)28(31)32/h2-13,29H,1,14-16H2
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n/an/a 680n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111521
PNG
(US8618158, NU8367)
Show SMILES OCc1cccc(COC2(N(Cc3ccc(cc3)[N+]([O-])=O)C(=O)c3ccccc23)c2ccc(Cl)cc2)c1 |w:9.8|
Show InChI InChI=1S/C29H23ClN2O5/c30-24-12-10-23(11-13-24)29(37-19-22-5-3-4-21(16-22)18-33)27-7-2-1-6-26(27)28(34)31(29)17-20-8-14-25(15-9-20)32(35)36/h1-16,33H,17-19H2
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n/an/a 732n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111544
PNG
(US8618158, NU8400)
Show SMILES CC(C)(C)c1ccc2C(=O)N(Cc3ccc(cc3)[N+]([O-])=O)C(OCC3(CO)CC3)(c2c1)c1ccc(Cl)cc1
Show InChI InChI=1S/C30H31ClN2O5/c1-28(2,3)22-8-13-25-26(16-22)30(21-6-9-23(31)10-7-21,38-19-29(18-34)14-15-29)32(27(25)35)17-20-4-11-24(12-5-20)33(36)37/h4-13,16,34H,14-15,17-19H2,1-3H3
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n/an/a 733n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111530
PNG
(US8618158, NU8397)
Show SMILES CC(C)(C)c1ccc2c(c1)C(=O)N(Cc1ccc(cc1)[N+]([O-])=O)C2(O)c1ccc(Cl)cc1
Show InChI InChI=1S/C25H23ClN2O4/c1-24(2,3)18-8-13-22-21(14-18)23(29)27(15-16-4-11-20(12-5-16)28(31)32)25(22,30)17-6-9-19(26)10-7-17/h4-14,30H,15H2,1-3H3
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n/an/a 837n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111538
PNG
(US8618158, NCL-00010490)
Show SMILES OC1(N(Cc2ccc(Br)cc2)C(=O)c2cccc(Cl)c12)c1ccc(Cl)cc1
Show InChI InChI=1S/C21H14BrCl2NO2/c22-15-8-4-13(5-9-15)12-25-20(26)17-2-1-3-18(24)19(17)21(25,27)14-6-10-16(23)11-7-14/h1-11,27H,12H2
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n/an/a 847n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111543
PNG
(US8618158, NCL-00010496)
Show SMILES OCC1(COC2(N(Cc3ccc(cc3)[N+]([O-])=O)C(=O)c3cc(F)ccc23)c2ccc(Cl)cc2)CC1
Show InChI InChI=1S/C26H22ClFN2O5/c27-19-5-3-18(4-6-19)26(35-16-25(15-31)11-12-25)23-10-7-20(28)13-22(23)24(32)29(26)14-17-1-8-21(9-2-17)30(33)34/h1-10,13,31H,11-12,14-16H2
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n/an/a 852n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111519
PNG
(US8618158, NU8365)
Show SMILES C[C@H](N1C(=O)c2ccccc2C1(OCCCCO)c1ccc(Cl)cc1)c1ccc(Cl)cc1 |r,w:11.13|
Show InChI InChI=1S/C26H25Cl2NO3/c1-18(19-8-12-21(27)13-9-19)29-25(31)23-6-2-3-7-24(23)26(29,32-17-5-4-16-30)20-10-14-22(28)15-11-20/h2-3,6-15,18,30H,4-5,16-17H2,1H3/t18-,26?/m0/s1
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n/an/a 869n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111552
PNG
(US8618158, NU8424)
Show SMILES OCC1(COC2(N(Cc3ccc(cc3)[N+]([O-])=O)C(=O)c3ccc(Br)cc23)c2ccc(Cl)cc2)CC1
Show InChI InChI=1S/C26H22BrClN2O5/c27-19-5-10-22-23(13-19)26(18-3-6-20(28)7-4-18,35-16-25(15-31)11-12-25)29(24(22)32)14-17-1-8-21(9-2-17)30(33)34/h1-10,13,31H,11-12,14-16H2
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n/an/a 902n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111520
PNG
(US8618158, NU8366)
Show SMILES OCc1ccc(COC2(N(Cc3ccc(cc3)[N+]([O-])=O)C(=O)c3ccccc23)c2ccc(Cl)cc2)cc1 |w:8.7|
Show InChI InChI=1S/C29H23ClN2O5/c30-24-13-11-23(12-14-24)29(37-19-22-7-5-21(18-33)6-8-22)27-4-2-1-3-26(27)28(34)31(29)17-20-9-15-25(16-10-20)32(35)36/h1-16,33H,17-19H2
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n/an/a 983n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111553
PNG
(US8618158, NU8425)
Show SMILES OCC1(COC2(N(Cc3ccc(cc3)[N+]([O-])=O)C(=O)c3cc(Br)ccc23)c2ccc(Cl)cc2)CC1
Show InChI InChI=1S/C26H22BrClN2O5/c27-19-5-10-23-22(13-19)24(32)29(14-17-1-8-21(9-2-17)30(33)34)26(23,18-3-6-20(28)7-4-18)35-16-25(15-31)11-12-25/h1-10,13,31H,11-12,14-16H2
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n/an/a 1.03E+3n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM50339375
PNG
((+/-)-2-(4-Bromobenzyl)-3-(4-chlorophenyl)-3-((1-(...)
Show SMILES OCC1(COC2(N(Cc3ccc(Br)cc3)C(=O)c3ccccc23)c2ccc(Cl)cc2)CC1
Show InChI InChI=1S/C26H23BrClNO3/c27-20-9-5-18(6-10-20)15-29-24(31)22-3-1-2-4-23(22)26(29,19-7-11-21(28)12-8-19)32-17-25(16-30)13-14-25/h1-12,30H,13-17H2
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n/an/a 1.20E+3n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111547
PNG
(US8618158, NCL-00013774 | US8618158, NCL-00013775 ...)
Show SMILES OCC1(COC2(N(Cc3ccc(cc3)[N+]([O-])=O)C(=O)c3cccc(Cl)c23)c2ccc(Cl)cc2)CC1
Show InChI InChI=1S/C26H22Cl2N2O5/c27-19-8-6-18(7-9-19)26(35-16-25(15-31)12-13-25)23-21(2-1-3-22(23)28)24(32)29(26)14-17-4-10-20(11-5-17)30(33)34/h1-11,31H,12-16H2
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n/an/a 1.26E+3n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM50339352
PNG
((+/-)-cis-3-(4-Chlorophenyl)-3-(4-hydroxycyclopent...)
Show SMILES O[C@H]1C[C@@H](OC2(N(Cc3ccc(cc3)[N+]([O-])=O)C(=O)c3ccccc23)c2ccc(Cl)cc2)C=C1 |r,c:36|
Show InChI InChI=1S/C26H21ClN2O5/c27-19-9-7-18(8-10-19)26(34-22-14-13-21(30)15-22)24-4-2-1-3-23(24)25(31)28(26)16-17-5-11-20(12-6-17)29(32)33/h1-14,21-22,30H,15-16H2/t21-,22+,26?/m1/s1
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n/an/a 1.40E+3n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM50339351
PNG
((+/-)-cis-3-(4-Chlorophenyl)-3-(4-hydroxycyclopent...)
Show SMILES Cc1ccc(CN2C(=O)c3ccccc3C2(O[C@@H]2C[C@H](O)C=C2)c2ccc(Cl)cc2)cc1 |r,c:23|
Show InChI InChI=1S/C27H24ClNO3/c1-18-6-8-19(9-7-18)17-29-26(31)24-4-2-3-5-25(24)27(29,20-10-12-21(28)13-11-20)32-23-15-14-22(30)16-23/h2-15,22-23,30H,16-17H2,1H3/t22-,23+,27?/m1/s1
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n/an/a 1.40E+3n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111525
PNG
(US8618158, NU8392)
Show SMILES OCCCOC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2ccccc12)c1ccc(Br)cc1 |w:5.4|
Show InChI InChI=1S/C24H21BrN2O5/c25-19-10-8-18(9-11-19)24(32-15-3-14-28)22-5-2-1-4-21(22)23(29)26(24)16-17-6-12-20(13-7-17)27(30)31/h1-2,4-13,28H,3,14-16H2
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n/an/a 1.40E+3n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111548
PNG
(US8618158, NU8412)
Show SMILES Cc1ccc2c(c1)C(=O)N(Cc1ccc(cc1)[N+]([O-])=O)C2(O)c1ccc(Cl)cc1
Show InChI InChI=1S/C22H17ClN2O4/c1-14-2-11-20-19(12-14)21(26)24(13-15-3-9-18(10-4-15)25(28)29)22(20,27)16-5-7-17(23)8-6-16/h2-12,27H,13H2,1H3
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n/an/a 1.46E+3n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111559
PNG
(US8618158, NCL-00014529)
Show SMILES OCC1(COC2(N(Cc3ccc(I)cc3)C(=O)c3ccccc23)c2ccc(Cl)cc2)CC1 |w:5.4|
Show InChI InChI=1S/C26H23ClINO3/c27-20-9-7-19(8-10-20)26(32-17-25(16-30)13-14-25)23-4-2-1-3-22(23)24(31)29(26)15-18-5-11-21(28)12-6-18/h1-12,30H,13-17H2
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n/an/a 1.50E+3n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM50339440
PNG
((+/-)-cis-3-(4-Chlorophenyl)-3-(4-hydroxycyclopent...)
Show SMILES O[C@H]1C[C@@H](OC2(N(Cc3ccc(Cl)cc3)C(=O)c3ccccc23)c2ccc(Cl)cc2)C=C1 |r,c:34|
Show InChI InChI=1S/C26H21Cl2NO3/c27-19-9-5-17(6-10-19)16-29-25(31)23-3-1-2-4-24(23)26(29,18-7-11-20(28)12-8-18)32-22-14-13-21(30)15-22/h1-14,21-22,30H,15-16H2/t21-,22+,26?/m1/s1
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n/an/a 1.50E+3n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111536
PNG
(US8618158, NCL-00010488)
Show SMILES OC1(N(Cc2ccc(cc2)C#N)C(=O)c2cccc(Cl)c12)c1ccc(Cl)cc1
Show InChI InChI=1S/C22H14Cl2N2O2/c23-17-10-8-16(9-11-17)22(28)20-18(2-1-3-19(20)24)21(27)26(22)13-15-6-4-14(12-25)5-7-15/h1-11,28H,13H2
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n/an/a 1.62E+3n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM50339372
PNG
((+/-)-4-((1-(4-Chlorophenyl)-1-((1-(hydroxymethyl)...)
Show SMILES OCC1(COC2(N(Cc3ccc(cc3)C#N)C(=O)c3ccccc23)c2ccc(Cl)cc2)CC1
Show InChI InChI=1S/C27H23ClN2O3/c28-22-11-9-21(10-12-22)27(33-18-26(17-31)13-14-26)24-4-2-1-3-23(24)25(32)30(27)16-20-7-5-19(15-29)6-8-20/h1-12,31H,13-14,16-18H2
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n/an/a 1.79E+3n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111526
PNG
(US8618158, NU8393)
Show SMILES Cc1cccc2C(=O)N(Cc3ccc(cc3)[N+]([O-])=O)C(O)(c12)c1ccc(Cl)cc1
Show InChI InChI=1S/C22H17ClN2O4/c1-14-3-2-4-19-20(14)22(27,16-7-9-17(23)10-8-16)24(21(19)26)13-15-5-11-18(12-6-15)25(28)29/h2-12,27H,13H2,1H3
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n/an/a 2.20E+3n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111571
PNG
(US8618158, NCL-00016865)
Show SMILES Cc1ccc(CN2C(=O)c3ccccc3C2(OCC2(CO)CC2)c2ccc(Cl)cc2)cc1 |w:15.17|
Show InChI InChI=1S/C27H26ClNO3/c1-19-6-8-20(9-7-19)16-29-25(31)23-4-2-3-5-24(23)27(29,21-10-12-22(28)13-11-21)32-18-26(17-30)14-15-26/h2-13,30H,14-18H2,1H3
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n/an/a 2.30E+3n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111504
PNG
(US8618158, NU8292)
Show SMILES O[C@H]1C[C@@H](OC2(N(Cc3ccc(cc3)C#N)C(=O)c3ccccc23)c2ccc(Cl)cc2)C=C1 |r,c:35|
Show InChI InChI=1S/C27H21ClN2O3/c28-21-11-9-20(10-12-21)27(33-23-14-13-22(31)15-23)25-4-2-1-3-24(25)26(32)30(27)17-19-7-5-18(16-29)6-8-19/h1-14,22-23,31H,15,17H2/t22-,23+,27?/m1/s1
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n/an/a 2.30E+3n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM50339439
PNG
((+/-)-cis-2-Benzyl-3-(4-chlorophenyl)-3-(4-hydroxy...)
Show SMILES O[C@H]1C[C@@H](OC2(N(Cc3ccccc3)C(=O)c3ccccc23)c2ccc(Cl)cc2)C=C1 |r,c:33|
Show InChI InChI=1S/C26H22ClNO3/c27-20-12-10-19(11-13-20)26(31-22-15-14-21(29)16-22)24-9-5-4-8-23(24)25(30)28(26)17-18-6-2-1-3-7-18/h1-15,21-22,29H,16-17H2/t21-,22+,26?/m1/s1
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n/an/a 2.30E+3n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM50339374
PNG
((+/-)-2-(4-Chlorobenzyl)-3-(4-chlorophenyl)-3-((1-...)
Show SMILES OCC1(COC2(N(Cc3ccc(Cl)cc3)C(=O)c3ccccc23)c2ccc(Cl)cc2)CC1
Show InChI InChI=1S/C26H23Cl2NO3/c27-20-9-5-18(6-10-20)15-29-24(31)22-3-1-2-4-23(22)26(29,19-7-11-21(28)12-8-19)32-17-25(16-30)13-14-25/h1-12,30H,13-17H2
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n/an/a 2.31E+3n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111522
PNG
(US8618158, NU8380)
Show SMILES NCCCOC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2ccccc12)c1ccc(Cl)cc1 |w:5.4|
Show InChI InChI=1S/C24H22ClN3O4/c25-19-10-8-18(9-11-19)24(32-15-3-14-26)22-5-2-1-4-21(22)23(29)27(24)16-17-6-12-20(13-7-17)28(30)31/h1-2,4-13H,3,14-16,26H2
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n/an/a 2.46E+3n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111507
PNG
(US8618158, NU8368)
Show SMILES C[C@@H](N1C(=O)c2ccccc2C1(OCCCCO)c1ccc(Cl)cc1)c1ccc(Cl)cc1 |r,w:11.13|
Show InChI InChI=1S/C26H25Cl2NO3/c1-18(19-8-12-21(27)13-9-19)29-25(31)23-6-2-3-7-24(23)26(29,32-17-5-4-16-30)20-10-14-22(28)15-11-20/h2-3,6-15,18,30H,4-5,16-17H2,1H3/t18-,26?/m1/s1
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n/an/a 2.50E+3n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111574
PNG
(US8618158, NCL-00016896)
Show SMILES OCC1(COC2(N(Cc3ccc(cc3)[N+]([O-])=O)C(=O)c3ccccc23)c2ccc(F)cc2)CC1 |w:5.4|
Show InChI InChI=1S/C26H23FN2O5/c27-20-9-7-19(8-10-20)26(34-17-25(16-30)13-14-25)23-4-2-1-3-22(23)24(31)28(26)15-18-5-11-21(12-6-18)29(32)33/h1-12,30H,13-17H2
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n/an/a 2.70E+3n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111572
PNG
(US8618158, NCL-00016866)
Show SMILES COc1ccc(CN2C(=O)c3ccccc3C2(OCC2(CO)CC2)c2ccc(Cl)cc2)cc1 |w:16.18|
Show InChI InChI=1S/C27H26ClNO4/c1-32-22-12-6-19(7-13-22)16-29-25(31)23-4-2-3-5-24(23)27(29,20-8-10-21(28)11-9-20)33-18-26(17-30)14-15-26/h2-13,30H,14-18H2,1H3
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n/an/a 2.80E+3n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111541
PNG
(US8618158, NCL-00010494)
Show SMILES OC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)C2=C1CCCC2)c1ccc(Cl)cc1 |c:16|
Show InChI InChI=1S/C21H19ClN2O4/c22-16-9-7-15(8-10-16)21(26)19-4-2-1-3-18(19)20(25)23(21)13-14-5-11-17(12-6-14)24(27)28/h5-12,26H,1-4,13H2
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n/an/a 2.81E+3n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111506
PNG
(US8618158, NU8362)
Show SMILES OCCCCOC1(N(CCc2ccc(cc2)[N+]([O-])=O)C(=O)c2ccccc12)c1ccc(Cl)cc1 |w:6.5|
Show InChI InChI=1S/C26H25ClN2O5/c27-21-11-9-20(10-12-21)26(34-18-4-3-17-30)24-6-2-1-5-23(24)25(31)28(26)16-15-19-7-13-22(14-8-19)29(32)33/h1-2,5-14,30H,3-4,15-18H2
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n/an/a 3.20E+3n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111508
PNG
(US8618158, NU8370)
Show SMILES OCCCCOC1(N(Cc2ccc(cc2)C#N)C(=O)c2ccccc12)c1ccc(Cl)cc1 |w:6.5|
Show InChI InChI=1S/C26H23ClN2O3/c27-22-13-11-21(12-14-22)26(32-16-4-3-15-30)24-6-2-1-5-23(24)25(31)29(26)18-20-9-7-19(17-28)8-10-20/h1-2,5-14,30H,3-4,15-16,18H2
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n/an/a 3.50E+3n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111535
PNG
(US8618158, NCL-00010487)
Show SMILES OCC1(COC2(N(Cc3ccc(cc3)[N+]([O-])=O)C(=O)c3cc(Cl)c(Cl)cc23)c2ccc(Cl)cc2)CC1
Show InChI InChI=1S/C26H21Cl3N2O5/c27-18-5-3-17(4-6-18)26(36-15-25(14-32)9-10-25)21-12-23(29)22(28)11-20(21)24(33)30(26)13-16-1-7-19(8-2-16)31(34)35/h1-8,11-12,32H,9-10,13-15H2
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n/an/a 3.67E+3n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111533
PNG
(US8618158, NCL-00010485)
Show SMILES OC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2ccc(F)cc12)c1ccc(Cl)cc1
Show InChI InChI=1S/C21H14ClFN2O4/c22-15-5-3-14(4-6-15)21(27)19-11-16(23)7-10-18(19)20(26)24(21)12-13-1-8-17(9-2-13)25(28)29/h1-11,27H,12H2
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n/an/a 3.76E+3n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111557
PNG
(US8618158, NCL-00016654)
Show SMILES OC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2c1cccc2Cl)c1ccc(Cl)cc1 |w:1.0|
Show InChI InChI=1S/C21H14Cl2N2O4/c22-15-8-6-14(7-9-15)21(27)17-2-1-3-18(23)19(17)20(26)24(21)12-13-4-10-16(11-5-13)25(28)29/h1-11,27H,12H2
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n/an/a 4.54E+3n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111528
PNG
(US8618158, NU8395)
Show SMILES Cc1ccc2C(=O)N(Cc3ccc(cc3)[N+]([O-])=O)C(O)(c2c1)c1ccc(Cl)cc1
Show InChI InChI=1S/C22H17ClN2O4/c1-14-2-11-19-20(12-14)22(27,16-5-7-17(23)8-6-16)24(21(19)26)13-15-3-9-18(10-4-15)25(28)29/h2-12,27H,13H2,1H3
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n/an/a 5.08E+3n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111534
PNG
(US8618158, NCL-00010486)
Show SMILES OC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2cc(F)ccc12)c1ccc(Cl)cc1
Show InChI InChI=1S/C21H14ClFN2O4/c22-15-5-3-14(4-6-15)21(27)19-10-7-16(23)11-18(19)20(26)24(21)12-13-1-8-17(9-2-13)25(28)29/h1-11,27H,12H2
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n/an/a 5.19E+3n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111549
PNG
(US8618158, NU8413)
Show SMILES OC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2cc(Br)ccc12)c1ccc(Cl)cc1
Show InChI InChI=1S/C21H14BrClN2O4/c22-15-5-10-19-18(11-15)20(26)24(12-13-1-8-17(9-2-13)25(28)29)21(19,27)14-3-6-16(23)7-4-14/h1-11,27H,12H2
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n/an/a 5.37E+3n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111550
PNG
(US8618158, NU8414)
Show SMILES OC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2ccc(Br)cc12)c1ccc(Cl)cc1
Show InChI InChI=1S/C21H14BrClN2O4/c22-15-5-10-18-19(11-15)21(27,14-3-6-16(23)7-4-14)24(20(18)26)12-13-1-8-17(9-2-13)25(28)29/h1-11,27H,12H2
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n/an/a 5.68E+3n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111527
PNG
(US8618158, NU8394)
Show SMILES Cc1cccc2c1C(=O)N(Cc1ccc(cc1)[N+]([O-])=O)C2(O)c1ccc(Cl)cc1
Show InChI InChI=1S/C22H17ClN2O4/c1-14-3-2-4-19-20(14)21(26)24(13-15-5-11-18(12-6-15)25(28)29)22(19,27)16-7-9-17(23)10-8-16/h2-12,27H,13H2,1H3
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n/an/a 6.90E+3n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111566
PNG
(US8618158, NCL-00016656)
Show SMILES OCC1(COC2(N(Cc3ccc(cc3)[N+]([O-])=O)C(=O)c3ccccc23)c2ccccc2)CC1 |w:5.4|
Show InChI InChI=1S/C26H24N2O5/c29-17-25(14-15-25)18-33-26(20-6-2-1-3-7-20)23-9-5-4-8-22(23)24(30)27(26)16-19-10-12-21(13-11-19)28(31)32/h1-13,29H,14-18H2
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n/an/a 8.30E+3n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111551
PNG
(US8618158, NU8418)
Show SMILES CC(N1C(=O)c2ccccc2C1(OCC1(CO)CC1)c1ccc(Cl)cc1)c1ccc(Cl)cc1
Show InChI InChI=1S/C27H25Cl2NO3/c1-18(19-6-10-21(28)11-7-19)30-25(32)23-4-2-3-5-24(23)27(30,20-8-12-22(29)13-9-20)33-17-26(16-31)14-15-26/h2-13,18,31H,14-17H2,1H3
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n/an/a 8.80E+3n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM50339380
PNG
((+/-)-3-(4-Chlorophenyl)-2-((S)-1-(4-chlorophenyl)...)
Show SMILES C[C@H](N1C(=O)c2ccccc2C1(OCC1(CO)CC1)c1ccc(Cl)cc1)c1ccc(Cl)cc1 |r|
Show InChI InChI=1S/C27H25Cl2NO3/c1-18(19-6-10-21(28)11-7-19)30-25(32)23-4-2-3-5-24(23)27(30,20-8-12-22(29)13-9-20)33-17-26(16-31)14-15-26/h2-13,18,31H,14-17H2,1H3/t18-,27?/m0/s1
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n/an/a 8.90E+3n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111537
PNG
(US8618158, NCL-00010489)
Show SMILES OC1(N(Cc2ccc(cc2)C#N)C(=O)c2c1cccc2Cl)c1ccc(Cl)cc1
Show InChI InChI=1S/C22H14Cl2N2O2/c23-17-10-8-16(9-11-17)22(28)18-2-1-3-19(24)20(18)21(27)26(22)13-15-6-4-14(12-25)5-7-15/h1-11,28H,13H2
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n/an/a 8.95E+3n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111567
PNG
(US8618158, NCL-00016657)
Show SMILES OC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2ccccc12)c1ccc(F)cc1 |w:1.0|
Show InChI InChI=1S/C21H15FN2O4/c22-16-9-7-15(8-10-16)21(26)19-4-2-1-3-18(19)20(25)23(21)13-14-5-11-17(12-6-14)24(27)28/h1-12,26H,13H2
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n/an/a 9.46E+3n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM50339392
PNG
((+/-)-3-(4-chlorophenyl)-3-((1-(hydroxymethyl)cycl...)
Show SMILES OCC1(COC2(N(Cc3ccccn3)C(=O)c3ccccc23)c2ccc(Cl)cc2)CC1
Show InChI InChI=1S/C25H23ClN2O3/c26-19-10-8-18(9-11-19)25(31-17-24(16-29)12-13-24)22-7-2-1-6-21(22)23(30)28(25)15-20-5-3-4-14-27-20/h1-11,14,29H,12-13,15-17H2
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n/an/a 1.06E+4n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111529
PNG
(US8618158, NU8396)
Show SMILES CC(C)(C)c1ccc2C(=O)N(Cc3ccc(cc3)[N+]([O-])=O)C(O)(c2c1)c1ccc(Cl)cc1
Show InChI InChI=1S/C25H23ClN2O4/c1-24(2,3)18-8-13-21-22(14-18)25(30,17-6-9-19(26)10-7-17)27(23(21)29)15-16-4-11-20(12-5-16)28(31)32/h4-14,30H,15H2,1-3H3
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n/an/a 1.27E+4n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111505
PNG
(US8618158, NU8294)
Show SMILES CCCN1C(=O)c2ccccc2C1(O[C@@H]1C[C@H](O)C=C1)c1ccc(Cl)cc1 |r,c:20|
Show InChI InChI=1S/C22H22ClNO3/c1-2-13-24-21(26)19-5-3-4-6-20(19)22(24,15-7-9-16(23)10-8-15)27-18-12-11-17(25)14-18/h3-12,17-18,25H,2,13-14H2,1H3/t17-,18+,22?/m1/s1
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n/an/a 1.51E+4n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111560
PNG
(CHEMBL1688293 | US8618158, NCL-00014531)
Show SMILES CC(=O)c1ccc(CN2C(=O)c3ccccc3C2(OCC2(CO)CC2)c2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C28H26ClNO4/c1-19(32)21-8-6-20(7-9-21)16-30-26(33)24-4-2-3-5-25(24)28(30,22-10-12-23(29)13-11-22)34-18-27(17-31)14-15-27/h2-13,31H,14-18H2,1H3
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n/an/a 1.70E+4n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111575
PNG
(US8618158, NCL-00016897)
Show SMILES OC1(N(Cc2ccc(cc2)N=O)C(=O)c2ccc(F)c(Cl)c12)c1ccc(Cl)cc1 |w:1.0|
Show InChI InChI=1S/C21H13Cl2FN2O3/c22-14-5-3-13(4-6-14)21(28)18-16(9-10-17(24)19(18)23)20(27)26(21)11-12-1-7-15(25-29)8-2-12/h1-10,28H,11H2
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n/an/a 3.40E+4n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111564
PNG
(US8618158, NCL-00016107)
Show SMILES OCC1(COC2(N(Cc3cccc(Br)c3)C(=O)c3ccccc23)c2ccc(Cl)cc2)CC1 |w:5.4|
Show InChI InChI=1S/C26H23BrClNO3/c27-20-5-3-4-18(14-20)15-29-24(31)22-6-1-2-7-23(22)26(29,19-8-10-21(28)11-9-19)32-17-25(16-30)12-13-25/h1-11,14,30H,12-13,15-17H2
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n/an/a 4.70E+4n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111563
PNG
(US8618158, NCL-00016106)
Show SMILES OCC1(COC2(N(Cc3cccc4ccccc34)C(=O)c3ccccc23)c2ccc(Cl)cc2)CC1 |w:5.4|
Show InChI InChI=1S/C30H26ClNO3/c31-24-14-12-23(13-15-24)30(35-20-29(19-33)16-17-29)27-11-4-3-10-26(27)28(34)32(30)18-22-8-5-7-21-6-1-2-9-25(21)22/h1-15,33H,16-20H2
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n/an/a 4.90E+4n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111565
PNG
(US8618158, NCL-00016655)
Show SMILES OC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2ccccc12)c1ccccc1 |w:1.0|
Show InChI InChI=1S/C21H16N2O4/c24-20-18-8-4-5-9-19(18)21(25,16-6-2-1-3-7-16)22(20)14-15-10-12-17(13-11-15)23(26)27/h1-13,25H,14H2
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n/an/a 8.70E+4n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111558
PNG
(CHEMBL1688161 | US8618158, NCL-00016045)
Show SMILES CC(=O)c1ccc(CN2C(=O)c3ccccc3C2(O)c2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C23H18ClNO3/c1-15(26)17-8-6-16(7-9-17)14-25-22(27)20-4-2-3-5-21(20)23(25,28)18-10-12-19(24)13-11-18/h2-13,28H,14H2,1H3
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n/an/a 8.90E+4n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))		BDBM111561
PNG
(US8618158, NCL-00016046)
Show SMILES OC1(N(Cc2cccc3ccccc23)C(=O)c2ccccc12)c1ccc(Cl)cc1 |w:1.0|
Show InChI InChI=1S/C25H18ClNO2/c26-20-14-12-19(13-15-20)25(29)23-11-4-3-10-22(23)24(28)27(25)16-18-8-5-7-17-6-1-2-9-21(17)18/h1-15,29H,16H2
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n/an/a 9.60E+4n/an/an/an/an/a25



Cancer Research Technology Limited

US Patent


Assay Description
Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...

US Patent US8618158 (2013)


BindingDB Entry DOI: 10.7270/Q27D2STZ
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%