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Patent code US8633208

Compile Data Set for Download or QSAR
Found 48 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM15581
PNG
(CHEMBL8706 | CLG | CLORGILINE | Clorgyline | N-[3-...)
Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C
Show InChI InChI=1S/C13H15Cl2NO/c1-3-7-16(2)8-4-9-17-13-6-5-11(14)10-12(13)15/h1,5-6,10H,4,7-9H2,2H3
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US Patent
n/an/a 27n/an/an/an/an/an/a



Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM113080
PNG
(US8633208, 23)
Show SMILES FC(F)(F)Oc1ccc(cc1)-c1ccc2cc(ccc2n1)-n1ccnc1
Show InChI InChI=1S/C19H12F3N3O/c20-19(21,22)26-16-5-1-13(2-6-16)17-7-3-14-11-15(4-8-18(14)24-17)25-10-9-23-12-25/h1-12H
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n/an/a 150n/an/an/an/an/an/a



Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM113058
PNG
(US8633208, 1)
Show SMILES c1cn(cn1)-c1ccc2nc(ncc2c1)-c1ccccc1
Show InChI InChI=1S/C17H12N4/c1-2-4-13(5-3-1)17-19-11-14-10-15(6-7-16(14)20-17)21-9-8-18-12-21/h1-12H
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n/an/a 220n/an/an/an/an/an/a



Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM113077
PNG
(US8633208, 20)
Show SMILES c1cn(cn1)-c1ccc2nc(ccc2c1)-c1ccoc1
Show InChI InChI=1S/C16H11N3O/c1-3-16(13-5-8-20-10-13)18-15-4-2-14(9-12(1)15)19-7-6-17-11-19/h1-11H
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n/an/a 250n/an/an/an/an/an/a



Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM113081
PNG
(US8633208, 24)
Show SMILES Cc1cc(OC(F)(F)F)ccc1-c1ccc2cc(ccc2n1)-n1ccnc1
Show InChI InChI=1S/C20H14F3N3O/c1-13-10-16(27-20(21,22)23)4-5-17(13)19-6-2-14-11-15(3-7-18(14)25-19)26-9-8-24-12-26/h2-12H,1H3
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Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM113071
PNG
(US8633208, 14)
Show SMILES c1cn(cn1)-c1ccc2nc(ncc2c1)-c1ccc2occc2c1
Show InChI InChI=1S/C19H12N4O/c1-4-18-13(5-8-24-18)9-14(1)19-21-11-15-10-16(2-3-17(15)22-19)23-7-6-20-12-23/h1-12H
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n/an/a 350n/an/an/an/an/an/a



Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM113082
PNG
(US8633208, 25)
Show SMILES CS(=O)(=O)c1ccc(cc1)-c1ccc2cc(ccc2n1)-n1ccnc1
Show InChI InChI=1S/C19H15N3O2S/c1-25(23,24)17-6-2-14(3-7-17)18-8-4-15-12-16(5-9-19(15)21-18)22-11-10-20-13-22/h2-13H,1H3
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n/an/a 450n/an/an/an/an/an/a



Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM15579
PNG
(CHEMBL972 | DEPRENYL | L-Deprenyl | N-methyl-N-[(2...)
Show SMILES C[C@H](Cc1ccccc1)N(C)CC#C |r|
Show InChI InChI=1S/C13H17N/c1-4-10-14(3)12(2)11-13-8-6-5-7-9-13/h1,5-9,12H,10-11H2,2-3H3/t12-/m1/s1
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n/an/a 480n/an/an/an/an/an/a



Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM113075
PNG
(US8633208, 18)
Show SMILES COc1ccc(cc1)-c1ccc2cc(ccc2n1)-n1ccnc1
Show InChI InChI=1S/C19H15N3O/c1-23-17-6-2-14(3-7-17)18-8-4-15-12-16(5-9-19(15)21-18)22-11-10-20-13-22/h2-13H,1H3
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n/an/a 670n/an/an/an/an/an/a



Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM50019848
PNG
(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1...)
Show SMILES C1CN=C(N1)C1COc2ccccc2O1 |c:2|
Show InChI InChI=1S/C11H12N2O2/c1-2-4-9-8(3-1)14-7-10(15-9)11-12-5-6-13-11/h1-4,10H,5-7H2,(H,12,13)
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Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM50019848
PNG
(2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1...)
Show SMILES C1CN=C(N1)C1COc2ccccc2O1 |c:2|
Show InChI InChI=1S/C11H12N2O2/c1-2-4-9-8(3-1)14-7-10(15-9)11-12-5-6-13-11/h1-4,10H,5-7H2,(H,12,13)
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Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM113074
PNG
(US8633208, 17)
Show SMILES c1cn(cn1)-c1ccc2nc(ccc2c1)-c1ccccc1
Show InChI InChI=1S/C18H13N3/c1-2-4-14(5-3-1)17-8-6-15-12-16(7-9-18(15)20-17)21-11-10-19-13-21/h1-13H
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n/an/a 1.13E+3n/an/an/an/an/an/a



Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM113079
PNG
(US8633208, 22)
Show SMILES CN(C)c1ccc(cc1)-c1ccc2cc(ccc2n1)-n1ccnc1
Show InChI InChI=1S/C20H18N4/c1-23(2)17-6-3-15(4-7-17)19-9-5-16-13-18(8-10-20(16)22-19)24-12-11-21-14-24/h3-14H,1-2H3
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n/an/a 1.49E+3n/an/an/an/an/an/a



Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM113061
PNG
(US8633208, 4)
Show SMILES Cc1cn(cn1)-c1ccc2nc(ncc2c1)-c1ccccc1
Show InChI InChI=1S/C18H14N4/c1-13-11-22(12-20-13)16-7-8-17-15(9-16)10-19-18(21-17)14-5-3-2-4-6-14/h2-12H,1H3
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n/an/a 2.06E+3n/an/an/an/an/an/a



Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM113079
PNG
(US8633208, 22)
Show SMILES CN(C)c1ccc(cc1)-c1ccc2cc(ccc2n1)-n1ccnc1
Show InChI InChI=1S/C20H18N4/c1-23(2)17-6-3-15(4-7-17)19-9-5-16-13-18(8-10-20(16)22-19)24-12-11-21-14-24/h3-14H,1-2H3
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n/an/a 2.09E+3n/an/an/an/an/an/a



Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM113078
PNG
(US8633208, 21)
Show SMILES Fc1ccc(cc1)-c1ccc2cc(ccc2n1)-n1ccnc1
Show InChI InChI=1S/C18H12FN3/c19-15-4-1-13(2-5-15)17-7-3-14-11-16(6-8-18(14)21-17)22-10-9-20-12-22/h1-12H
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Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM113081
PNG
(US8633208, 24)
Show SMILES Cc1cc(OC(F)(F)F)ccc1-c1ccc2cc(ccc2n1)-n1ccnc1
Show InChI InChI=1S/C20H14F3N3O/c1-13-10-16(27-20(21,22)23)4-5-17(13)19-6-2-14-11-15(3-7-18(14)25-19)26-9-8-24-12-26/h2-12H,1H3
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Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM113073
PNG
(US8633208, 16)
Show SMILES C1Oc2ccc(cc2O1)-c1ccc2cc(ccc2n1)-n1ccnc1
Show InChI InChI=1S/C19H13N3O2/c1-4-16(14-2-6-18-19(10-14)24-12-23-18)21-17-5-3-15(9-13(1)17)22-8-7-20-11-22/h1-11H,12H2
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Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM113062
PNG
(US8633208, 5)
Show SMILES Cc1cncn1-c1ccc2nc(ncc2c1)-c1ccccc1
Show InChI InChI=1S/C18H14N4/c1-13-10-19-12-22(13)16-7-8-17-15(9-16)11-20-18(21-17)14-5-3-2-4-6-14/h2-12H,1H3
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Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM113072
PNG
(US8633208, 15)
Show SMILES C1COc2cc(ccc2O1)-c1ncc2cc(ccc2n1)-n1ccnc1
Show InChI InChI=1S/C19H14N4O2/c1-4-17-18(25-8-7-24-17)10-13(1)19-21-11-14-9-15(2-3-16(14)22-19)23-6-5-20-12-23/h1-6,9-12H,7-8H2
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Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM113071
PNG
(US8633208, 14)
Show SMILES c1cn(cn1)-c1ccc2nc(ncc2c1)-c1ccc2occc2c1
Show InChI InChI=1S/C19H12N4O/c1-4-18-13(5-8-24-18)9-14(1)19-21-11-15-10-16(2-3-17(15)22-19)23-7-6-20-12-23/h1-12H
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Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM113059
PNG
(US8633208, 2)
Show SMILES Cc1nccn1-c1ccc2nc(ncc2c1)-c1ccccc1
Show InChI InChI=1S/C18H14N4/c1-13-19-9-10-22(13)16-7-8-17-15(11-16)12-20-18(21-17)14-5-3-2-4-6-14/h2-12H,1H3
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n/an/a 1.00E+4n/an/an/an/an/an/a



Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM113077
PNG
(US8633208, 20)
Show SMILES c1cn(cn1)-c1ccc2nc(ccc2c1)-c1ccoc1
Show InChI InChI=1S/C16H11N3O/c1-3-16(13-5-8-20-10-13)18-15-4-2-14(9-12(1)15)19-7-6-17-11-19/h1-11H
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n/an/a 1.00E+4n/an/an/an/an/an/a



Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM113070
PNG
(US8633208, 13)
Show SMILES C1Oc2ccc(cc2O1)-c1ncc2cc(ccc2n1)-n1ccnc1
Show InChI InChI=1S/C18H12N4O2/c1-4-16-17(24-11-23-16)8-12(1)18-20-9-13-7-14(2-3-15(13)21-18)22-6-5-19-10-22/h1-10H,11H2
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Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM113080
PNG
(US8633208, 23)
Show SMILES FC(F)(F)Oc1ccc(cc1)-c1ccc2cc(ccc2n1)-n1ccnc1
Show InChI InChI=1S/C19H12F3N3O/c20-19(21,22)26-16-5-1-13(2-6-16)17-7-3-14-11-15(4-8-18(14)24-17)25-10-9-23-12-25/h1-12H
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n/an/a 1.00E+4n/an/an/an/an/an/a



Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM113062
PNG
(US8633208, 5)
Show SMILES Cc1cncn1-c1ccc2nc(ncc2c1)-c1ccccc1
Show InChI InChI=1S/C18H14N4/c1-13-10-19-12-22(13)16-7-8-17-15(9-16)11-20-18(21-17)14-5-3-2-4-6-14/h2-12H,1H3
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Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM113076
PNG
(US8633208, 19)
Show SMILES COc1ccccc1-c1ccc2cc(ccc2n1)-n1ccnc1
Show InChI InChI=1S/C19H15N3O/c1-23-19-5-3-2-4-16(19)18-8-6-14-12-15(7-9-17(14)21-18)22-11-10-20-13-22/h2-13H,1H3
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Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM113066
PNG
(US8633208, 9)
Show SMILES Cc1cn(cn1)-c1ccc2nc(ncc2c1)-c1ccc2OCOc2c1
Show InChI InChI=1S/C19H14N4O2/c1-12-9-23(10-21-12)15-3-4-16-14(6-15)8-20-19(22-16)13-2-5-17-18(7-13)25-11-24-17/h2-10H,11H2,1H3
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Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM113058
PNG
(US8633208, 1)
Show SMILES c1cn(cn1)-c1ccc2nc(ncc2c1)-c1ccccc1
Show InChI InChI=1S/C17H12N4/c1-2-4-13(5-3-1)17-19-11-14-10-15(6-7-16(14)20-17)21-9-8-18-12-21/h1-12H
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Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM113075
PNG
(US8633208, 18)
Show SMILES COc1ccc(cc1)-c1ccc2cc(ccc2n1)-n1ccnc1
Show InChI InChI=1S/C19H15N3O/c1-23-17-6-2-14(3-7-17)18-8-4-15-12-16(5-9-19(15)21-18)22-11-10-20-13-22/h2-13H,1H3
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Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM113061
PNG
(US8633208, 4)
Show SMILES Cc1cn(cn1)-c1ccc2nc(ncc2c1)-c1ccccc1
Show InChI InChI=1S/C18H14N4/c1-13-11-22(12-20-13)16-7-8-17-15(9-16)10-19-18(21-17)14-5-3-2-4-6-14/h2-12H,1H3
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Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM113076
PNG
(US8633208, 19)
Show SMILES COc1ccccc1-c1ccc2cc(ccc2n1)-n1ccnc1
Show InChI InChI=1S/C19H15N3O/c1-23-19-5-3-2-4-16(19)18-8-6-14-12-15(7-9-17(14)21-18)22-11-10-20-13-22/h2-13H,1H3
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Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM113073
PNG
(US8633208, 16)
Show SMILES C1Oc2ccc(cc2O1)-c1ccc2cc(ccc2n1)-n1ccnc1
Show InChI InChI=1S/C19H13N3O2/c1-4-16(14-2-6-18-19(10-14)24-12-23-18)21-17-5-3-15(9-13(1)17)22-8-7-20-11-22/h1-11H,12H2
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n/an/a 1.00E+4n/an/an/an/an/an/a



Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM113064
PNG
(US8633208, 7)
Show SMILES COc1ccccc1-c1ncc2cc(ccc2n1)-n1cnc(C)c1
Show InChI InChI=1S/C19H16N4O/c1-13-11-23(12-21-13)15-7-8-17-14(9-15)10-20-19(22-17)16-5-3-4-6-18(16)24-2/h3-12H,1-2H3
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Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM113070
PNG
(US8633208, 13)
Show SMILES C1Oc2ccc(cc2O1)-c1ncc2cc(ccc2n1)-n1ccnc1
Show InChI InChI=1S/C18H12N4O2/c1-4-16-17(24-11-23-16)8-12(1)18-20-9-13-7-14(2-3-15(13)21-18)22-6-5-19-10-22/h1-10H,11H2
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n/an/a 1.00E+4n/an/an/an/an/an/a



Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM113074
PNG
(US8633208, 17)
Show SMILES c1cn(cn1)-c1ccc2nc(ccc2c1)-c1ccccc1
Show InChI InChI=1S/C18H13N3/c1-2-4-14(5-3-1)17-8-6-15-12-16(7-9-18(15)20-17)21-11-10-19-13-21/h1-13H
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n/an/a 1.00E+4n/an/an/an/an/an/a



Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM113078
PNG
(US8633208, 21)
Show SMILES Fc1ccc(cc1)-c1ccc2cc(ccc2n1)-n1ccnc1
Show InChI InChI=1S/C18H12FN3/c19-15-4-1-13(2-5-15)17-7-3-14-11-16(6-8-18(14)21-17)22-10-9-20-12-22/h1-12H
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n/an/a 1.00E+4n/an/an/an/an/an/a



Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM113082
PNG
(US8633208, 25)
Show SMILES CS(=O)(=O)c1ccc(cc1)-c1ccc2cc(ccc2n1)-n1ccnc1
Show InChI InChI=1S/C19H15N3O2S/c1-25(23,24)17-6-2-14(3-7-17)18-8-4-15-12-16(5-9-19(15)21-18)22-11-10-20-13-22/h2-13H,1H3
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Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM113063
PNG
(US8633208, 6)
Show SMILES COc1ccc(cc1)-c1ncc2cc(ccc2n1)-n1cnc(C)c1
Show InChI InChI=1S/C19H16N4O/c1-13-11-23(12-21-13)16-5-8-18-15(9-16)10-20-19(22-18)14-3-6-17(24-2)7-4-14/h3-12H,1-2H3
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Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM113064
PNG
(US8633208, 7)
Show SMILES COc1ccccc1-c1ncc2cc(ccc2n1)-n1cnc(C)c1
Show InChI InChI=1S/C19H16N4O/c1-13-11-23(12-21-13)15-7-8-17-14(9-15)10-20-19(22-17)16-5-3-4-6-18(16)24-2/h3-12H,1-2H3
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Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM113066
PNG
(US8633208, 9)
Show SMILES Cc1cn(cn1)-c1ccc2nc(ncc2c1)-c1ccc2OCOc2c1
Show InChI InChI=1S/C19H14N4O2/c1-12-9-23(10-21-12)15-3-4-16-14(6-15)8-20-19(22-16)13-2-5-17-18(7-13)25-11-24-17/h2-10H,11H2,1H3
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Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM113072
PNG
(US8633208, 15)
Show SMILES C1COc2cc(ccc2O1)-c1ncc2cc(ccc2n1)-n1ccnc1
Show InChI InChI=1S/C19H14N4O2/c1-4-17-18(25-8-7-24-17)10-13(1)19-21-11-14-9-15(2-3-16(14)22-19)23-6-5-20-12-23/h1-6,9-12H,7-8H2
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Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM113059
PNG
(US8633208, 2)
Show SMILES Cc1nccn1-c1ccc2nc(ncc2c1)-c1ccccc1
Show InChI InChI=1S/C18H14N4/c1-13-19-9-10-22(13)16-7-8-17-15(11-16)12-20-18(21-17)14-5-3-2-4-6-14/h2-12H,1H3
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Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM113063
PNG
(US8633208, 6)
Show SMILES COc1ccc(cc1)-c1ncc2cc(ccc2n1)-n1cnc(C)c1
Show InChI InChI=1S/C19H16N4O/c1-13-11-23(12-21-13)16-5-8-18-15(9-16)10-20-19(22-18)14-3-6-17(24-2)7-4-14/h3-12H,1-2H3
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Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM15581
PNG
(CHEMBL8706 | CLG | CLORGILINE | Clorgyline | N-[3-...)
Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C
Show InChI InChI=1S/C13H15Cl2NO/c1-3-7-16(2)8-4-9-17-13-6-5-11(14)10-12(13)15/h1,5-6,10H,4,7-9H2,2H3
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n/an/a 1.43E+4n/an/an/an/an/an/a



Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM15579
PNG
(CHEMBL972 | DEPRENYL | L-Deprenyl | N-methyl-N-[(2...)
Show SMILES C[C@H](Cc1ccccc1)N(C)CC#C |r|
Show InChI InChI=1S/C13H17N/c1-4-10-14(3)12(2)11-13-8-6-5-7-9-13/h1,5-9,12H,10-11H2,2-3H3/t12-/m1/s1
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n/an/a 1.91E+4n/an/an/an/an/an/a



Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] B


(Homo sapiens (Human))		BDBM85213
PNG
(Agmatine | CAS_306-60-5 | CHEMBL58343 | NSC_199 | ...)
Show SMILES [#7]-[#6]-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7]
Show InChI InChI=1S/C5H14N4/c6-3-1-2-4-9-5(7)8/h1-4,6H2,(H4,7,8,9)
PDB

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n/an/a 1.00E+5n/an/an/an/an/an/a



Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))		BDBM85213
PNG
(Agmatine | CAS_306-60-5 | CHEMBL58343 | NSC_199 | ...)
Show SMILES [#7]-[#6]-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7]
Show InChI InChI=1S/C5H14N4/c6-3-1-2-4-9-5(7)8/h1-4,6H2,(H4,7,8,9)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MMDB
PC cid
PC sid
UniChem

Patents

Similars
US Patent
n/an/a 1.00E+5n/an/an/an/an/an/a



Rottapharm S.p.A

US Patent


Assay Description
Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...

US Patent US8633208 (2014)


BindingDB Entry DOI: 10.7270/Q23J3BMD
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%