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Patent code US8637558

Compile Data Set for Download or QSAR
Found 130 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50347953
PNG
(CHEMBL1800140 | US8637558, 15)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCC2CCCCC2)c(Br)c1 |w:7.8,t:1|
Show InChI InChI=1S/C18H20BrNO3S/c19-14-10-13(11-16-17(21)20-18(22)24-16)6-7-15(14)23-9-8-12-4-2-1-3-5-12/h6-7,10-12H,1-5,8-9H2,(H,20,21,22)
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US Patent
n/an/a 6.60n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50347952
PNG
(CHEMBL1800139 | US8637558, 11)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCC2CCCCC2)c(Cl)c1 |w:7.8,t:1|
Show InChI InChI=1S/C18H20ClNO3S/c19-14-10-13(11-16-17(21)20-18(22)24-16)6-7-15(14)23-9-8-12-4-2-1-3-5-12/h6-7,10-12H,1-5,8-9H2,(H,20,21,22)
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US Patent
n/an/a 7.20n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50347956
PNG
(CHEMBL1800143 | US8637558, 32)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCCC2CCCCC2)c(Cl)c1 |w:7.8,t:1|
Show InChI InChI=1S/C19H22ClNO3S/c20-15-11-14(12-17-18(22)21-19(23)25-17)8-9-16(15)24-10-4-7-13-5-2-1-3-6-13/h8-9,11-13H,1-7,10H2,(H,21,22,23)
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US Patent
n/an/a 10.3n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118019
PNG
(US8637558, 34)
Show SMILES OC1=NC(=O)C(S1)=Cc1cccc(OCCC2CCCCC2)c1Cl |w:7.8,t:1|
Show InChI InChI=1S/C18H20ClNO3S/c19-16-13(11-15-17(21)20-18(22)24-15)7-4-8-14(16)23-10-9-12-5-2-1-3-6-12/h4,7-8,11-12H,1-3,5-6,9-10H2,(H,20,21,22)
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US Patent
n/an/a 17.9n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50438430
PNG
(CHEMBL2414240 | US8637558, 18)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCC2CCCCC2)cc1Cl |w:7.8,t:1|
Show InChI InChI=1S/C18H20ClNO3S/c19-15-11-14(23-9-8-12-4-2-1-3-5-12)7-6-13(15)10-16-17(21)20-18(22)24-16/h6-7,10-12H,1-5,8-9H2,(H,20,21,22)
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n/an/a 19.6n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50438403
PNG
(CHEMBL2414160 | US8637558, 69)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCc2ccccc2)c(Cl)c1 |w:7.8,t:1|
Show InChI InChI=1S/C18H14ClNO3S/c19-14-10-13(11-16-17(21)20-18(22)24-16)6-7-15(14)23-9-8-12-4-2-1-3-5-12/h1-7,10-11H,8-9H2,(H,20,21,22)
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US Patent
n/an/a 19.8n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118042
PNG
(US8637558, 66)
Show SMILES OCC(=O)C1CCC(COc2ccc(C=C3SC(O)=NC3=O)cc2)CC1 |w:14.13,c:18,(-9.19,-2.44,;-7.85,-1.67,;-6.52,-2.44,;-6.52,-3.98,;-5.19,-1.67,;-3.85,-2.44,;-2.52,-1.67,;-2.52,-.13,;-1.18,.64,;.15,-.13,;1.48,.64,;2.82,-.13,;4.15,.64,;4.15,2.18,;5.48,2.95,;6.82,2.18,;6.82,.64,;8.28,.16,;9.05,-1.17,;9.19,1.41,;8.28,2.65,;9.05,3.98,;2.82,2.95,;1.48,2.18,;-3.85,.64,;-5.19,-.13,)|
Show InChI InChI=1S/C19H21NO5S/c21-10-16(22)14-5-1-13(2-6-14)11-25-15-7-3-12(4-8-15)9-17-18(23)20-19(24)26-17/h3-4,7-9,13-14,21H,1-2,5-6,10-11H2,(H,20,23,24)
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n/an/a 20.4n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118056
PNG
(US8637558, 84)
Show SMILES COc1cc(C=C2SC(O)=NC2=O)ccc1OCCCC1CCCCC1 |w:5.4,c:9|
Show InChI InChI=1S/C20H25NO4S/c1-24-17-12-15(13-18-19(22)21-20(23)26-18)9-10-16(17)25-11-5-8-14-6-3-2-4-7-14/h9-10,12-14H,2-8,11H2,1H3,(H,21,22,23)
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US Patent
n/an/a 22.1n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118012
PNG
(US8637558, 8)
Show SMILES OCc1cc(C=C2SC(O)=NC2=O)ccc1OCCC1CCCCC1 |w:5.4,c:9|
Show InChI InChI=1S/C19H23NO4S/c21-12-15-10-14(11-17-18(22)20-19(23)25-17)6-7-16(15)24-9-8-13-4-2-1-3-5-13/h6-7,10-11,13,21H,1-5,8-9,12H2,(H,20,22,23)
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US Patent
n/an/a 23n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50347957
PNG
(CHEMBL1800144 | US8637558, 33)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCCCC2CCCCC2)c(Cl)c1 |w:7.8,t:1|
Show InChI InChI=1S/C20H24ClNO3S/c21-16-12-15(13-18-19(23)22-20(24)26-18)9-10-17(16)25-11-5-4-8-14-6-2-1-3-7-14/h9-10,12-14H,1-8,11H2,(H,22,23,24)
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US Patent
n/an/a 26.3n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50347955
PNG
(CHEMBL1800142 | US8637558, 31)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCC2CCCCC2)c(Cl)c1 |w:7.8,t:1|
Show InChI InChI=1S/C17H18ClNO3S/c18-13-8-12(9-15-16(20)19-17(21)23-15)6-7-14(13)22-10-11-4-2-1-3-5-11/h6-9,11H,1-5,10H2,(H,19,20,21)
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US Patent
n/an/a 26.9n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118057
PNG
(US8637558, 89)
Show SMILES CC(CC1CCC(C)=CC1)Oc1ccc(C=C2SC(O)=NC2=O)cc1 |w:15.15,c:7,20|
Show InChI InChI=1S/C20H23NO3S/c1-13-3-5-15(6-4-13)11-14(2)24-17-9-7-16(8-10-17)12-18-19(22)21-20(23)25-18/h3,7-10,12,14-15H,4-6,11H2,1-2H3,(H,21,22,23)
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US Patent
n/an/a 28.4n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118041
PNG
(US8637558, 65)
Show SMILES CC1CCC(COc2ccc(C=C3SC(O)=NC3=O)cc2C(F)(F)F)CC1 |w:11.10,c:15,(-7.85,-3.21,;-6.52,-2.44,;-6.52,-.9,;-5.19,-.13,;-3.85,-.9,;-2.52,-.13,;-1.18,-.9,;.15,-.13,;1.48,-.9,;2.82,-.13,;2.82,1.41,;4.15,2.18,;5.48,1.41,;5.48,-.13,;6.95,-.61,;7.72,-1.94,;7.85,.64,;6.95,1.88,;7.72,3.21,;1.48,2.18,;.15,1.41,;-1.18,2.18,;-2.52,1.41,;-1.58,3.66,;-2.67,2.57,;-3.85,-2.44,;-5.19,-3.21,)|
Show InChI InChI=1S/C19H20F3NO3S/c1-11-2-4-12(5-3-11)10-26-15-7-6-13(8-14(15)19(20,21)22)9-16-17(24)23-18(25)27-16/h6-9,11-12H,2-5,10H2,1H3,(H,23,24,25)
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US Patent
n/an/a 31.4n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50438402
PNG
(CHEMBL2414161 | US8637558, 70)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCCc2ccccc2)c(Cl)c1 |w:7.8,t:1|
Show InChI InChI=1S/C19H16ClNO3S/c20-15-11-14(12-17-18(22)21-19(23)25-17)8-9-16(15)24-10-4-7-13-5-2-1-3-6-13/h1-3,5-6,8-9,11-12H,4,7,10H2,(H,21,22,23)
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US Patent
n/an/a 38.1n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50378637
PNG
(CHEMBL84603 | US8637558, 35)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCC2CCCC2)cc1 |w:7.8,t:1|
Show InChI InChI=1S/C16H17NO3S/c18-15-14(21-16(19)17-15)9-11-5-7-13(8-6-11)20-10-12-3-1-2-4-12/h5-9,12H,1-4,10H2,(H,17,18,19)
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n/an/a 42.5n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118047
PNG
(US8637558, 75)
Show SMILES OC1=NC(=O)C(S1)=Cc1cccc(OCCCc2ccccc2)c1Cl |w:7.8,t:1|
Show InChI InChI=1S/C19H16ClNO3S/c20-17-14(12-16-18(22)21-19(23)25-16)9-4-10-15(17)24-11-5-8-13-6-2-1-3-7-13/h1-4,6-7,9-10,12H,5,8,11H2,(H,21,22,23)
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n/an/a 44.9n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50438404
PNG
(CHEMBL2414159 | US8637558, 68)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCc2ccccc2)c(Cl)c1 |w:7.8,t:1|
Show InChI InChI=1S/C17H12ClNO3S/c18-13-8-12(9-15-16(20)19-17(21)23-15)6-7-14(13)22-10-11-4-2-1-3-5-11/h1-9H,10H2,(H,19,20,21)
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n/an/a 47.5n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50438401
PNG
(CHEMBL2414162 | US8637558, 71)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCCCc2ccccc2)c(Cl)c1 |w:7.8,t:1|
Show InChI InChI=1S/C20H18ClNO3S/c21-16-12-15(13-18-19(23)22-20(24)26-18)9-10-17(16)25-11-5-4-8-14-6-2-1-3-7-14/h1-3,6-7,9-10,12-13H,4-5,8,11H2,(H,22,23,24)
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US Patent
n/an/a 47.5n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50347954
PNG
(CHEMBL1800141 | US8637558, 30)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OC2CCCCC2)c(Cl)c1 |w:7.8,t:1|
Show InChI InChI=1S/C16H16ClNO3S/c17-12-8-10(9-14-15(19)18-16(20)22-14)6-7-13(12)21-11-4-2-1-3-5-11/h6-9,11H,1-5H2,(H,18,19,20)
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n/an/a 48.9n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118029
PNG
(US8637558, 51)
Show SMILES Cc1cc(C=C2SC(O)=NC2=O)ccc1OCC1CCCCC1 |w:4.3,c:8|
Show InChI InChI=1S/C18H21NO3S/c1-12-9-14(10-16-17(20)19-18(21)23-16)7-8-15(12)22-11-13-5-3-2-4-6-13/h7-10,13H,2-6,11H2,1H3,(H,19,20,21)
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n/an/a 49.8n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118050
PNG
(US8637558, 78)
Show SMILES COc1cc(C=C2SC(O)=NC2=O)cc(Cl)c1OCCC1CCCCC1 |w:5.4,c:9|
Show InChI InChI=1S/C19H22ClNO4S/c1-24-15-10-13(11-16-18(22)21-19(23)26-16)9-14(20)17(15)25-8-7-12-5-3-2-4-6-12/h9-12H,2-8H2,1H3,(H,21,22,23)
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n/an/a 50.6n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118018
PNG
(US8637558, 20)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCC2CCCCC2)c(F)c1 |w:7.8,t:1|
Show InChI InChI=1S/C18H20FNO3S/c19-14-10-13(11-16-17(21)20-18(22)24-16)6-7-15(14)23-9-8-12-4-2-1-3-5-12/h6-7,10-12H,1-5,8-9H2,(H,20,21,22)
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n/an/a 50.8n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50347949
PNG
(CHEMBL599406 | US8637558, 46)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCC2CCCCC2)cc1 |w:7.8,t:1|
Show InChI InChI=1S/C18H21NO3S/c20-17-16(23-18(21)19-17)12-14-6-8-15(9-7-14)22-11-10-13-4-2-1-3-5-13/h6-9,12-13H,1-5,10-11H2,(H,19,20,21)
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n/an/a 50.9n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50438398
PNG
(CHEMBL2414165 | US8637558, 87)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCCc2ccccc2)cc1Cl |w:7.8,t:1|
Show InChI InChI=1S/C19H16ClNO3S/c20-16-12-15(24-10-4-7-13-5-2-1-3-6-13)9-8-14(16)11-17-18(22)21-19(23)25-17/h1-3,5-6,8-9,11-12H,4,7,10H2,(H,21,22,23)
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n/an/a 52n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118046
PNG
(US8637558, 74)
Show SMILES OC1=NC(=O)C(S1)=Cc1cccc(OCCCCc2ccccc2)c1Cl |w:7.8,t:1|
Show InChI InChI=1S/C20H18ClNO3S/c21-18-15(13-17-19(23)22-20(24)26-17)10-6-11-16(18)25-12-5-4-9-14-7-2-1-3-8-14/h1-3,6-8,10-11,13H,4-5,9,12H2,(H,22,23,24)
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n/an/a 54.3n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118013
PNG
(US8637558, 9)
Show SMILES Cc1cc(C=C2SC(O)=NC2=O)ccc1OCCC1CCCCC1 |w:4.3,c:8|
Show InChI InChI=1S/C19H23NO3S/c1-13-11-15(12-17-18(21)20-19(22)24-17)7-8-16(13)23-10-9-14-5-3-2-4-6-14/h7-8,11-12,14H,2-6,9-10H2,1H3,(H,20,21,22)
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n/an/a 55n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118039
PNG
(US8637558, 63)
Show SMILES OC1=NC(=O)C(S1)=Cc1cccc(OCC2CCCCC2)c1Cl |w:7.8,t:1|
Show InChI InChI=1S/C17H18ClNO3S/c18-15-12(9-14-16(20)19-17(21)23-14)7-4-8-13(15)22-10-11-5-2-1-3-6-11/h4,7-9,11H,1-3,5-6,10H2,(H,19,20,21)
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n/an/a 57.6n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118040
PNG
(US8637558, 64)
Show SMILES OC1=NC(=O)C(S1)=Cc1cccc(OCCCC2CCCCC2)c1Cl |w:7.8,t:1|
Show InChI InChI=1S/C19H22ClNO3S/c20-17-14(12-16-18(22)21-19(23)25-16)9-4-10-15(17)24-11-5-8-13-6-2-1-3-7-13/h4,9-10,12-13H,1-3,5-8,11H2,(H,21,22,23)
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n/an/a 59n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118027
PNG
(US8637558, 49)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCC2CCCCC2)c(c1)[N+]([O-])=O |w:7.8,t:1|
Show InChI InChI=1S/C18H20N2O5S/c21-17-16(26-18(22)19-17)11-13-6-7-15(14(10-13)20(23)24)25-9-8-12-4-2-1-3-5-12/h6-7,10-12H,1-5,8-9H2,(H,19,21,22)
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n/an/a 59.5n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118025
PNG
(US8637558, 47)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCCC2CCCCC2)cc1 |w:7.8,t:1|
Show InChI InChI=1S/C19H23NO3S/c21-18-17(24-19(22)20-18)13-15-8-10-16(11-9-15)23-12-4-7-14-5-2-1-3-6-14/h8-11,13-14H,1-7,12H2,(H,20,21,22)
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n/an/a 62.2n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50378639
PNG
(CHEMBL599018 | US8637558, 37)
Show SMILES CC1CCC(COc2ccc(C=C3SC(O)=NC3=O)cc2)CC1 |w:11.10,c:15,(4.23,-1.81,;3.51,-1.4,;3.51,-.57,;2.8,-.16,;2.08,-.57,;1.37,-.16,;.65,-.57,;-.06,-.16,;-.06,.67,;-.78,1.08,;-1.49,.67,;-2.2,1.08,;-2.92,.67,;-3.01,-.15,;-3.81,-.33,;-4.15,-1.08,;-4.23,.39,;-3.67,1,;-3.84,1.81,;-1.49,-.16,;-.78,-.57,;2.08,-1.4,;2.8,-1.81,)|
Show InChI InChI=1S/C18H21NO3S/c1-12-2-4-14(5-3-12)11-22-15-8-6-13(7-9-15)10-16-17(20)19-18(21)23-16/h6-10,12,14H,2-5,11H2,1H3,(H,19,20,21)
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n/an/a 66.4n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118017
PNG
(US8637558, 16)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCC2CCCCC2)c(c1)C(F)(F)F |w:7.8,t:1|
Show InChI InChI=1S/C19H20F3NO3S/c20-19(21,22)14-10-13(11-16-17(24)23-18(25)27-16)6-7-15(14)26-9-8-12-4-2-1-3-5-12/h6-7,10-12H,1-5,8-9H2,(H,23,24,25)
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n/an/a 71.9n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50438397
PNG
(CHEMBL2414166 | US8637558, 88)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCCCc2ccccc2)cc1Cl |w:7.8,t:1|
Show InChI InChI=1S/C20H18ClNO3S/c21-17-13-16(25-11-5-4-8-14-6-2-1-3-7-14)10-9-15(17)12-18-19(23)22-20(24)26-18/h1-3,6-7,9-10,12-13H,4-5,8,11H2,(H,22,23,24)
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n/an/a 81n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50438423
PNG
(CHEMBL2414140 | US8637558, 101)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCc2cccs2)c(Cl)c1 |w:7.8,t:1|
Show InChI InChI=1S/C16H12ClNO3S2/c17-12-8-10(9-14-15(19)18-16(20)23-14)3-4-13(12)21-6-5-11-2-1-7-22-11/h1-4,7-9H,5-6H2,(H,18,19,20)
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n/an/a 84.1n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118067
PNG
(US8637558, 100)
Show SMILES OC1=NC(=O)C(S1)=Cc1cccc(OCCCCC2CCCCC2)c1Cl |w:7.8,t:1|
Show InChI InChI=1S/C20H24ClNO3S/c21-18-15(13-17-19(23)22-20(24)26-17)10-6-11-16(18)25-12-5-4-9-14-7-2-1-3-8-14/h6,10-11,13-14H,1-5,7-9,12H2,(H,22,23,24)
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n/an/a 94.5n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118014
PNG
(US8637558, 10)
Show SMILES COc1cc(C=C2SC(O)=NC2=O)cc(CO)c1OCCC1CCCCC1 |w:5.4,c:9|
Show InChI InChI=1S/C20H25NO5S/c1-25-16-10-14(11-17-19(23)21-20(24)27-17)9-15(12-22)18(16)26-8-7-13-5-3-2-4-6-13/h9-11,13,22H,2-8,12H2,1H3,(H,21,23,24)
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n/an/a 94.5n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50378619
PNG
(CHEMBL590265 | US8637558, 3)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCc2cccs2)cc1 |w:7.8,t:1|
Show InChI InChI=1S/C16H13NO3S2/c18-15-14(22-16(19)17-15)10-11-3-5-12(6-4-11)20-8-7-13-2-1-9-21-13/h1-6,9-10H,7-8H2,(H,17,18,19)
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n/an/a 95.9n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118073
PNG
(CHEMBL2414145 | US8637558, 108)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCC2CCCC2)c(Cl)c1 |w:7.8,t:1|
Show InChI InChI=1S/C17H18ClNO3S/c18-13-9-12(10-15-16(20)19-17(21)23-15)5-6-14(13)22-8-7-11-3-1-2-4-11/h5-6,9-11H,1-4,7-8H2,(H,19,20,21)
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n/an/a 99.3n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118030
PNG
(US8637558, 52)
Show SMILES Cc1cc(C=C2SC(O)=NC2=O)ccc1OCCCC1CCCCC1 |w:4.3,c:8|
Show InChI InChI=1S/C20H25NO3S/c1-14-12-16(13-18-19(22)21-20(23)25-18)9-10-17(14)24-11-5-8-15-6-3-2-4-7-15/h9-10,12-13,15H,2-8,11H2,1H3,(H,21,22,23)
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n/an/a 104n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118052
PNG
(US8637558, 80)
Show SMILES COc1ccc(C=C2SC(O)=NC2=O)c(Cl)c1OCCC1CCCCC1 |w:6.5,c:10|
Show InChI InChI=1S/C19H22ClNO4S/c1-24-14-8-7-13(11-15-18(22)21-19(23)26-15)16(20)17(14)25-10-9-12-5-3-2-4-6-12/h7-8,11-12H,2-6,9-10H2,1H3,(H,21,22,23)
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n/an/a 110n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50378631
PNG
(CHEMBL598397 | US8637558, 24)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCC2CCCC2)cc1 |w:7.8,t:1|
Show InChI InChI=1S/C17H19NO3S/c19-16-15(22-17(20)18-16)11-13-5-7-14(8-6-13)21-10-9-12-3-1-2-4-12/h5-8,11-12H,1-4,9-10H2,(H,18,19,20)
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n/an/a 115n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118033
PNG
(US8637558, 55)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCc2ccccc2)cc1 |w:7.8,t:1|
Show InChI InChI=1S/C18H15NO3S/c20-17-16(23-18(21)19-17)12-14-6-8-15(9-7-14)22-11-10-13-4-2-1-3-5-13/h1-9,12H,10-11H2,(H,19,20,21)
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n/an/a 117n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118045
PNG
(US8637558, 73)
Show SMILES OC1=NC(=O)C(S1)=Cc1cccc(OCCc2ccccc2)c1Cl |w:7.8,t:1|
Show InChI InChI=1S/C18H14ClNO3S/c19-16-13(11-15-17(21)20-18(22)24-15)7-4-8-14(16)23-10-9-12-5-2-1-3-6-12/h1-8,11H,9-10H2,(H,20,21,22)
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n/an/a 122n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50378638
PNG
(CHEMBL591466 | US8637558, 36)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCc2ccc(CCl)cc2)cc1 |w:7.8,t:1|
Show InChI InChI=1S/C18H14ClNO3S/c19-10-13-1-3-14(4-2-13)11-23-15-7-5-12(6-8-15)9-16-17(21)20-18(22)24-16/h1-9H,10-11H2,(H,20,21,22)
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n/an/a 125n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118080
PNG
(US8637558, 117 | US8637558, 125)
Show SMILES Oc1[nH]c(=O)sc1Cc1ccc(OCC2CCCCC2)c(Cl)c1
Show InChI InChI=1S/C17H20ClNO3S/c18-13-8-12(9-15-16(20)19-17(21)23-15)6-7-14(13)22-10-11-4-2-1-3-5-11/h6-8,11,20H,1-5,9-10H2,(H,19,21)
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n/an/a 125n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118059
PNG
(US8637558, 91)
Show SMILES CC1CCC(COc2cccc(C=C3SC(O)=NC3=O)c2Cl)CC1 |w:12.11,c:16,(-7.85,3.21,;-6.52,2.44,;-5.19,3.21,;-3.85,2.44,;-3.85,.9,;-2.52,.13,;-1.18,.9,;.15,.13,;.15,-1.41,;1.48,-2.18,;2.82,-1.41,;2.82,.13,;4.15,.9,;5.48,.13,;5.48,-1.41,;6.95,-1.88,;7.72,-3.21,;7.85,-.64,;6.95,.61,;7.72,1.94,;1.48,.9,;1.48,2.44,;-5.19,.13,;-6.52,.9,)|
Show InChI InChI=1S/C18H20ClNO3S/c1-11-5-7-12(8-6-11)10-23-14-4-2-3-13(16(14)19)9-15-17(21)20-18(22)24-15/h2-4,9,11-12H,5-8,10H2,1H3,(H,20,21,22)
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n/an/a 135n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118053
PNG
(US8637558, 81)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCC2CCCCC2)cc1C(F)(F)F |w:7.8,t:1|
Show InChI InChI=1S/C19H20F3NO3S/c20-19(21,22)15-11-14(26-9-8-12-4-2-1-3-5-12)7-6-13(15)10-16-17(24)23-18(25)27-16/h6-7,10-12H,1-5,8-9H2,(H,23,24,25)
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n/an/a 137n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118085
PNG
(US8637558, 122)
Show SMILES Oc1[nH]c(=O)sc1Cc1ccc(OCCCC2CCCCC2)c(Cl)c1
Show InChI InChI=1S/C19H24ClNO3S/c20-15-11-14(12-17-18(22)21-19(23)25-17)8-9-16(15)24-10-4-7-13-5-2-1-3-6-13/h8-9,11,13,22H,1-7,10,12H2,(H,21,23)
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n/an/a 143n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50378621
PNG
(CHEMBL610221 | US8637558, 4)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCc2ccsc2)cc1 |w:7.8,t:1|
Show InChI InChI=1S/C16H13NO3S2/c18-15-14(22-16(19)17-15)9-11-1-3-13(4-2-11)20-7-5-12-6-8-21-10-12/h1-4,6,8-10H,5,7H2,(H,17,18,19)
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n/an/a 149n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118072
PNG
(US8637558, 107)
Show SMILES OC1=NC(=O)C(S1)=Cc1cccc(OCCC2CCCC2)c1Cl |w:7.8,t:1|
Show InChI InChI=1S/C17H18ClNO3S/c18-15-12(10-14-16(20)19-17(21)23-14)6-3-7-13(15)22-9-8-11-4-1-2-5-11/h3,6-7,10-11H,1-2,4-5,8-9H2,(H,19,20,21)
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n/an/a 154n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118089
PNG
(US8637558, 127)
Show SMILES Oc1[nH]c(=O)sc1Cc1ccc(OCCC2CCCCC2)cc1Cl
Show InChI InChI=1S/C18H22ClNO3S/c19-15-11-14(23-9-8-12-4-2-1-3-5-12)7-6-13(15)10-16-17(21)20-18(22)24-16/h6-7,11-12,21H,1-5,8-10H2,(H,20,22)
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n/an/a 158n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118038
PNG
(CHEMBL598880 | US8637558, 62)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCC2COc3ccccc3O2)cc1 |w:7.8,t:1|
Show InChI InChI=1S/C19H15NO5S/c21-18-17(26-19(22)20-18)9-12-5-7-13(8-6-12)23-10-14-11-24-15-3-1-2-4-16(15)25-14/h1-9,14H,10-11H2,(H,20,21,22)
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n/an/a 172n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118060
PNG
(US8637558, 92)
Show SMILES CC(C)OCCOc1cccc(C=C2SC(O)=NC2=O)c1Cl |w:12.11,c:16|
Show InChI InChI=1S/C15H16ClNO4S/c1-9(2)20-6-7-21-11-5-3-4-10(13(11)16)8-12-14(18)17-15(19)22-12/h3-5,8-9H,6-7H2,1-2H3,(H,17,18,19)
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n/an/a 173n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118083
PNG
(US8637558, 120)
Show SMILES Oc1[nH]c(=O)sc1Cc1ccc(OCCC2CCCCC2)c(Cl)c1
Show InChI InChI=1S/C18H22ClNO3S/c19-14-10-13(11-16-17(21)20-18(22)24-16)6-7-15(14)23-9-8-12-4-2-1-3-5-12/h6-7,10,12,21H,1-5,8-9,11H2,(H,20,22)
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n/an/a 173n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118049
PNG
(US8637558, 77)
Show SMILES OC1=NC(=O)C(S1)=Cc1cc(F)c(OCCC2CCCCC2)c(Cl)c1 |w:7.8,t:1|
Show InChI InChI=1S/C18H19ClFNO3S/c19-13-8-12(10-15-17(22)21-18(23)25-15)9-14(20)16(13)24-7-6-11-4-2-1-3-5-11/h8-11H,1-7H2,(H,21,22,23)
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n/an/a 177n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50438399
PNG
(CHEMBL2414164 | US8637558, 86)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCc2ccccc2)cc1Cl |w:7.8,t:1|
Show InChI InChI=1S/C18H14ClNO3S/c19-15-11-14(23-9-8-12-4-2-1-3-5-12)7-6-13(15)10-16-17(21)20-18(22)24-16/h1-7,10-11H,8-9H2,(H,20,21,22)
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n/an/a 178n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118034
PNG
(US8637558, 56)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCCc2ccccc2)cc1 |w:7.8,t:1|
Show InChI InChI=1S/C19H17NO3S/c21-18-17(24-19(22)20-18)13-15-8-10-16(11-9-15)23-12-4-7-14-5-2-1-3-6-14/h1-3,5-6,8-11,13H,4,7,12H2,(H,20,21,22)
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n/an/a 186n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118079
PNG
(US8637558, 115 | US8637558, 123)
Show SMILES Oc1[nH]c(=O)sc1Cc1ccc(OCC2CCCC2)cc1
Show InChI InChI=1S/C16H19NO3S/c18-15-14(21-16(19)17-15)9-11-5-7-13(8-6-11)20-10-12-3-1-2-4-12/h5-8,12,18H,1-4,9-10H2,(H,17,19)
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n/an/a 205n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118066
PNG
(US8637558, 99)
Show SMILES OC1=NC(=O)C(S1)=Cc1cccc(OC2CCCCC2)c1Cl |w:7.8,t:1|
Show InChI InChI=1S/C16H16ClNO3S/c17-14-10(9-13-15(19)18-16(20)22-13)5-4-8-12(14)21-11-6-2-1-3-7-11/h4-5,8-9,11H,1-3,6-7H2,(H,18,19,20)
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n/an/a 212n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118022
PNG
(US8637558, 42)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCC2CCCCC2)cc1 |w:7.8,t:1|
Show InChI InChI=1S/C17H19NO3S/c19-16-15(22-17(20)18-16)10-12-6-8-14(9-7-12)21-11-13-4-2-1-3-5-13/h6-10,13H,1-5,11H2,(H,18,19,20)
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n/an/a 217n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50378640
PNG
(CHEMBL599019 | US8637558, 61)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCOC2CCCCC2)cc1 |w:7.8,t:1|
Show InChI InChI=1S/C18H21NO4S/c20-17-16(24-18(21)19-17)12-13-6-8-15(9-7-13)23-11-10-22-14-4-2-1-3-5-14/h6-9,12,14H,1-5,10-11H2,(H,19,20,21)
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n/an/a 219n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118035
PNG
(US8637558, 57)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCCCc2ccccc2)cc1 |w:7.8,t:1|
Show InChI InChI=1S/C20H19NO3S/c22-19-18(25-20(23)21-19)14-16-9-11-17(12-10-16)24-13-5-4-8-15-6-2-1-3-7-15/h1-3,6-7,9-12,14H,4-5,8,13H2,(H,21,22,23)
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n/an/a 225n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118075
PNG
(US8637558, 110)
Show SMILES OC1=NC(=O)C(S1)=Cc1cccc(OCCOC2CCCCC2)c1Cl |w:7.8,t:1|
Show InChI InChI=1S/C18H20ClNO4S/c19-16-12(11-15-17(21)20-18(22)25-15)5-4-8-14(16)24-10-9-23-13-6-2-1-3-7-13/h4-5,8,11,13H,1-3,6-7,9-10H2,(H,20,21,22)
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n/an/a 233n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118062
PNG
(US8637558, 95)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OC2CCCCC2)cc1Cl |w:7.8,t:1|
Show InChI InChI=1S/C16H16ClNO3S/c17-13-9-12(21-11-4-2-1-3-5-11)7-6-10(13)8-14-15(19)18-16(20)22-14/h6-9,11H,1-5H2,(H,18,19,20)
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n/an/a 233n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50378629
PNG
(CHEMBL598182 | US8637558, 22)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCc2cccs2)cc1 |w:7.8,t:1|
Show InChI InChI=1S/C15H11NO3S2/c17-14-13(21-15(18)16-14)8-10-3-5-11(6-4-10)19-9-12-2-1-7-20-12/h1-8H,9H2,(H,16,17,18)
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n/an/a 251n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50378635
PNG
(CHEMBL597576 | US8637558, 27 | US8637558, 28)
Show SMILES Cc1ccc(COc2ccc(C=C3SC(O)=NC3=O)cc2)cc1 |w:11.10,c:15|
Show InChI InChI=1S/C18H15NO3S/c1-12-2-4-14(5-3-12)11-22-15-8-6-13(7-9-15)10-16-17(20)19-18(21)23-16/h2-10H,11H2,1H3,(H,19,20,21)
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n/an/a 255n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118044
PNG
(US8637558, 72)
Show SMILES OC1=NC(=O)C(S1)=Cc1cccc(OCc2ccccc2)c1Cl |w:7.8,t:1|
Show InChI InChI=1S/C17H12ClNO3S/c18-15-12(9-14-16(20)19-17(21)23-14)7-4-8-13(15)22-10-11-5-2-1-3-6-11/h1-9H,10H2,(H,19,20,21)
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n/an/a 257n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118036
PNG
(US8637558, 59)
Show SMILES CCOc1cc(C=C2SC(O)=NC2=O)ccc1OCCC1CCCCC1 |w:6.5,c:10|
Show InChI InChI=1S/C20H25NO4S/c1-2-24-17-12-15(13-18-19(22)21-20(23)26-18)8-9-16(17)25-11-10-14-6-4-3-5-7-14/h8-9,12-14H,2-7,10-11H2,1H3,(H,21,22,23)
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n/an/a 259n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118064
PNG
(US8637558, 97)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCCC2CCCCC2)cc1Cl |w:7.8,t:1|
Show InChI InChI=1S/C19H22ClNO3S/c20-16-12-15(24-10-4-7-13-5-2-1-3-6-13)9-8-14(16)11-17-18(22)21-19(23)25-17/h8-9,11-13H,1-7,10H2,(H,21,22,23)
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n/an/a 284n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118028
PNG
(US8637558, 50)
Show SMILES Nc1cc(C=C2SC(O)=NC2=O)ccc1OCCC1CCCCC1 |w:4.3,c:8|
Show InChI InChI=1S/C18H22N2O3S/c19-14-10-13(11-16-17(21)20-18(22)24-16)6-7-15(14)23-9-8-12-4-2-1-3-5-12/h6-7,10-12H,1-5,8-9,19H2,(H,20,21,22)
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n/an/a 286n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50438424
PNG
(CHEMBL2414139 | US8637558, 17)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCN2CCS(=O)(=O)CC2)c(Cl)c1 |w:7.8,t:1|
Show InChI InChI=1S/C16H17ClN2O5S2/c17-12-9-11(10-14-15(20)18-16(21)25-14)1-2-13(12)24-6-3-19-4-7-26(22,23)8-5-19/h1-2,9-10H,3-8H2,(H,18,20,21)
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n/an/a 308n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50378636
PNG
(CHEMBL607870 | US8637558, 29)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCc2ccc3OCOc3c2)cc1 |w:7.8,t:1|
Show InChI InChI=1S/C18H13NO5S/c20-17-16(25-18(21)19-17)8-11-1-4-13(5-2-11)22-9-12-3-6-14-15(7-12)24-10-23-14/h1-8H,9-10H2,(H,19,20,21)
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n/an/a 310n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118015
PNG
(US8637558, 12)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCCC2CCCCC2)c(c1)[N+]([O-])=O |w:7.8,t:1|
Show InChI InChI=1S/C19H22N2O5S/c22-18-17(27-19(23)20-18)12-14-8-9-16(15(11-14)21(24)25)26-10-4-7-13-5-2-1-3-6-13/h8-9,11-13H,1-7,10H2,(H,20,22,23)
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n/an/a 327n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50378630
PNG
(CHEMBL598183 | US8637558, 23)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCc2ccsc2)cc1 |w:7.8,t:1|
Show InChI InChI=1S/C15H11NO3S2/c17-14-13(21-15(18)16-14)7-10-1-3-12(4-2-10)19-8-11-5-6-20-9-11/h1-7,9H,8H2,(H,16,17,18)
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n/an/a 392n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118084
PNG
(US8637558, 121)
Show SMILES Cc1cc(Cc2sc(=O)[nH]c2O)ccc1OCCC1CCCCC1
Show InChI InChI=1S/C19H25NO3S/c1-13-11-15(12-17-18(21)20-19(22)24-17)7-8-16(13)23-10-9-14-5-3-2-4-6-14/h7-8,11,14,21H,2-6,9-10,12H2,1H3,(H,20,22)
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n/an/a 397n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118031
PNG
(US8637558, 53)
Show SMILES Cc1cc(C=C2SC(O)=NC2=O)ccc1OCCCCC1CCCCC1 |w:4.3,c:8|
Show InChI InChI=1S/C21H27NO3S/c1-15-13-17(14-19-20(23)22-21(24)26-19)10-11-18(15)25-12-6-5-9-16-7-3-2-4-8-16/h10-11,13-14,16H,2-9,12H2,1H3,(H,22,23,24)
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n/an/a 399n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50438400
PNG
(CHEMBL2414163 | US8637558, 85)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCc2ccccc2)cc1Cl |w:7.8,t:1|
Show InChI InChI=1S/C17H12ClNO3S/c18-14-9-13(22-10-11-4-2-1-3-5-11)7-6-12(14)8-15-16(20)19-17(21)23-15/h1-9H,10H2,(H,19,20,21)
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n/an/a 487n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50378620
PNG
(CHEMBL599002 | US8637558, 2)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCN2CCOCC2)cc1 |w:7.8,t:1|
Show InChI InChI=1S/C16H18N2O4S/c19-15-14(23-16(20)17-15)11-12-1-3-13(4-2-12)22-10-7-18-5-8-21-9-6-18/h1-4,11H,5-10H2,(H,17,19,20)
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n/an/a 515n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50378646
PNG
(CHEMBL598787 | US8637558, 58)
Show SMILES OCCN1C(=O)S\C(=C/c2ccc(OCCC3CCCCC3)cc2)C1=O
Show InChI InChI=1S/C20H25NO4S/c22-12-11-21-19(23)18(26-20(21)24)14-16-6-8-17(9-7-16)25-13-10-15-4-2-1-3-5-15/h6-9,14-15,22H,1-5,10-13H2/b18-14-
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n/an/a 526n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118080
PNG
(US8637558, 117 | US8637558, 125)
Show SMILES Oc1[nH]c(=O)sc1Cc1ccc(OCC2CCCCC2)c(Cl)c1
Show InChI InChI=1S/C17H20ClNO3S/c18-13-8-12(9-15-16(20)19-17(21)23-15)6-7-14(13)22-10-11-4-2-1-3-5-11/h6-8,11,20H,1-5,9-10H2,(H,19,21)
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n/an/a 526n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118023
PNG
(US8637558, 43)
Show SMILES CC1(COc2ccc(C=C3SC(O)=NC3=O)cc2)CCCCC1 |w:8.7,c:12|
Show InChI InChI=1S/C18H21NO3S/c1-18(9-3-2-4-10-18)12-22-14-7-5-13(6-8-14)11-15-16(20)19-17(21)23-15/h5-8,11H,2-4,9-10,12H2,1H3,(H,19,20,21)
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n/an/a 547n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50378623
PNG
(CHEMBL599004 | US8637558, 6)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCc2ccccn2)cc1 |w:7.8,t:1|
Show InChI InChI=1S/C17H14N2O3S/c20-16-15(23-17(21)19-16)11-12-4-6-14(7-5-12)22-10-8-13-3-1-2-9-18-13/h1-7,9,11H,8,10H2,(H,19,20,21)
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n/an/a 592n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118090
PNG
(US8637558, 128)
Show SMILES Cc1cc(Cc2sc(=O)[nH]c2O)ccc1OCCCC1CCCCC1
Show InChI InChI=1S/C20H27NO3S/c1-14-12-16(13-18-19(22)21-20(23)25-18)9-10-17(14)24-11-5-8-15-6-3-2-4-7-15/h9-10,12,15,22H,2-8,11,13H2,1H3,(H,21,23)
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n/an/a 667n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118068
PNG
(US8637558, 102)
Show SMILES COc1cc(C=C2SC(O)=NC2=O)ccc1OCCc1cccs1 |w:5.4,c:9|
Show InChI InChI=1S/C17H15NO4S2/c1-21-14-9-11(10-15-16(19)18-17(20)24-15)4-5-13(14)22-7-6-12-3-2-8-23-12/h2-5,8-10H,6-7H2,1H3,(H,18,19,20)
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n/an/a 682n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118016
PNG
(US8637558, 13)
Show SMILES OC1=NC(=S)C(S1)=Cc1ccc(OCCC2CCCCC2)cc1 |w:7.8,t:1|
Show InChI InChI=1S/C18H21NO2S2/c20-18-19-17(22)16(23-18)12-14-6-8-15(9-7-14)21-11-10-13-4-2-1-3-5-13/h6-9,12-13H,1-5,10-11H2,(H,19,20,22)
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n/an/a 689n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50378635
PNG
(CHEMBL597576 | US8637558, 27 | US8637558, 28)
Show SMILES Cc1ccc(COc2ccc(C=C3SC(O)=NC3=O)cc2)cc1 |w:11.10,c:15|
Show InChI InChI=1S/C18H15NO3S/c1-12-2-4-14(5-3-12)11-22-15-8-6-13(7-9-15)10-16-17(20)19-18(21)23-16/h2-10H,11H2,1H3,(H,19,20,21)
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n/an/a 728n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118020
PNG
(US8637558, 38)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCC2CCCCO2)cc1 |w:7.8,t:1|
Show InChI InChI=1S/C16H17NO4S/c18-15-14(22-16(19)17-15)9-11-4-6-12(7-5-11)21-10-13-3-1-2-8-20-13/h4-7,9,13H,1-3,8,10H2,(H,17,18,19)
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n/an/a 750n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118081
PNG
(US8637558, 118 | US8637558, 130)
Show SMILES Oc1[nH]c(=O)sc1Cc1ccc(OCCC2CCCC2)cc1
Show InChI InChI=1S/C17H21NO3S/c19-16-15(22-17(20)18-16)11-13-5-7-14(8-6-13)21-10-9-12-3-1-2-4-12/h5-8,12,19H,1-4,9-11H2,(H,18,20)
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n/an/a 777n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118048
PNG
(CHEMBL599395 | US8637558, 76)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCc2ccc(cc2)-c2ccccc2)cc1 |w:7.8,t:1|
Show InChI InChI=1S/C23H17NO3S/c25-22-21(28-23(26)24-22)14-16-8-12-20(13-9-16)27-15-17-6-10-19(11-7-17)18-4-2-1-3-5-18/h1-14H,15H2,(H,24,25,26)
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n/an/a 814n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118024
PNG
(US8637558, 45)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OC2CCCCC2)cc1 |w:7.8,t:1|
Show InChI InChI=1S/C16H17NO3S/c18-15-14(21-16(19)17-15)10-11-6-8-13(9-7-11)20-12-4-2-1-3-5-12/h6-10,12H,1-5H2,(H,17,18,19)
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n/an/a 822n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118079
PNG
(US8637558, 115 | US8637558, 123)
Show SMILES Oc1[nH]c(=O)sc1Cc1ccc(OCC2CCCC2)cc1
Show InChI InChI=1S/C16H19NO3S/c18-15-14(21-16(19)17-15)9-11-5-7-13(8-6-11)20-10-12-3-1-2-4-12/h5-8,12,18H,1-4,9-10H2,(H,17,19)
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n/an/a 854n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50378622
PNG
(CHEMBL599003 | US8637558, 1)
Show SMILES CC(C)OCCOc1ccc(C=C2SC(O)=NC2=O)cc1 |w:11.10,c:15|
Show InChI InChI=1S/C15H17NO4S/c1-10(2)19-7-8-20-12-5-3-11(4-6-12)9-13-14(17)16-15(18)21-13/h3-6,9-10H,7-8H2,1-2H3,(H,16,17,18)
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n/an/a 961n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118077
PNG
(US8637558, 113)
Show SMILES Oc1[nH]c(=O)sc1Cc1ccc(OCCC2CCCCC2)cc1
Show InChI InChI=1S/C18H23NO3S/c20-17-16(23-18(21)19-17)12-14-6-8-15(9-7-14)22-11-10-13-4-2-1-3-5-13/h6-9,13,20H,1-5,10-12H2,(H,19,21)
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n/an/a 977n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50145465
PNG
((Z)-5-(4-Benzyloxybenzylidene)thiazolidine-2,4-dio...)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCc2ccccc2)cc1 |w:7.8,t:1|
Show InChI InChI=1S/C17H13NO3S/c19-16-15(22-17(20)18-16)10-12-6-8-14(9-7-12)21-11-13-4-2-1-3-5-13/h1-10H,11H2,(H,18,19,20)
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n/an/a 1.04E+3n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118091
PNG
(US8637558, 129)
Show SMILES Oc1[nH]c(=O)sc1Cc1ccc(OCc2ccc(cc2)-c2ccccc2)cc1
Show InChI InChI=1S/C23H19NO3S/c25-22-21(28-23(26)24-22)14-16-8-12-20(13-9-16)27-15-17-6-10-19(11-7-17)18-4-2-1-3-5-18/h1-13,25H,14-15H2,(H,24,26)
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n/an/a 1.08E+3n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118054
PNG
(US8637558, 82)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCCCC2CCCCC2)c(c1)[N+]([O-])=O |w:7.8,t:1|
Show InChI InChI=1S/C20H24N2O5S/c23-19-18(28-20(24)21-19)13-15-9-10-17(16(12-15)22(25)26)27-11-5-4-8-14-6-2-1-3-7-14/h9-10,12-14H,1-8,11H2,(H,21,23,24)
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n/an/a 1.08E+3n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118070
PNG
(US8637558, 105)
Show SMILES Cc1ncsc1CCOc1cccc(C=C2SC(O)=NC2=O)c1Cl |w:14.14,c:19|
Show InChI InChI=1S/C16H13ClN2O3S2/c1-9-12(23-8-18-9)5-6-22-11-4-2-3-10(14(11)17)7-13-15(20)19-16(21)24-13/h2-4,7-8H,5-6H2,1H3,(H,19,20,21)
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n/an/a 1.09E+3n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118043
PNG
(US8637558, 67)
Show SMILES OCc1ccc(C=C2SC(O)=NC2=O)cc1OCCC1CCCCC1 |w:6.5,c:10|
Show InChI InChI=1S/C19H23NO4S/c21-12-15-7-6-14(11-17-18(22)20-19(23)25-17)10-16(15)24-9-8-13-4-2-1-3-5-13/h6-7,10-11,13,21H,1-5,8-9,12H2,(H,20,22,23)
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n/an/a 1.16E+3n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50378627
PNG
(CHEMBL590988 | US8637558, 19)
Show SMILES Cc1ncsc1CCOc1ccc(C=C2SC(O)=NC2=O)cc1 |w:13.13,c:18|
Show InChI InChI=1S/C16H14N2O3S2/c1-10-13(22-9-17-10)6-7-21-12-4-2-11(3-5-12)8-14-15(19)18-16(20)23-14/h2-5,8-9H,6-7H2,1H3,(H,18,19,20)
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n/an/a 1.17E+3n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50145471
PNG
(5-(4-(benzyloxy)benzyl)thiazolidine-2,4-dione | 5-...)
Show SMILES Oc1[nH]c(=O)sc1Cc1ccc(OCc2ccccc2)cc1
Show InChI InChI=1S/C17H15NO3S/c19-16-15(22-17(20)18-16)10-12-6-8-14(9-7-12)21-11-13-4-2-1-3-5-13/h1-9,19H,10-11H2,(H,18,20)
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n/an/a 1.26E+3n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50378618
PNG
(CHEMBL599407 | US8637558, 5)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCN2CCS(=O)(=O)CC2)cc1 |w:7.8,t:1|
Show InChI InChI=1S/C16H18N2O5S2/c19-15-14(24-16(20)17-15)11-12-1-3-13(4-2-12)23-8-5-18-6-9-25(21,22)10-7-18/h1-4,11H,5-10H2,(H,17,19,20)
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n/an/a 1.37E+3n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118082
PNG
(US8637558, 119 | US8637558, 126)
Show SMILES Oc1[nH]c(=O)sc1Cc1ccc(OCCN2CCS(=O)(=O)CC2)cc1
Show InChI InChI=1S/C16H22N2O5S2/c19-15-14(24-16(20)17-15)11-12-1-3-13(4-2-12)23-8-5-18-6-9-25(21,22)10-7-18/h1-4,9,19,21-22,25H,5-8,10-11H2,(H,17,20)
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n/an/a 1.39E+3n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50378626
PNG
(CHEMBL599416 | US8637558, 14)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCN2CCCCC2)cc1 |w:7.8,t:1|
Show InChI InChI=1S/C17H20N2O3S/c20-16-15(23-17(21)18-16)12-13-4-6-14(7-5-13)22-11-10-19-8-2-1-3-9-19/h4-7,12H,1-3,8-11H2,(H,18,20,21)
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n/an/a 1.43E+3n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118065
PNG
(US8637558, 98)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCCCC2CCCCC2)cc1Cl |w:7.8,t:1|
Show InChI InChI=1S/C20H24ClNO3S/c21-17-13-16(25-11-5-4-8-14-6-2-1-3-7-14)10-9-15(17)12-18-19(23)22-20(24)26-18/h9-10,12-14H,1-8,11H2,(H,22,23,24)
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n/an/a 1.65E+3n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118069
PNG
(US8637558, 103)
Show SMILES COc1ccc(\C=C2/SC(=O)NC2=O)cc1OCCc1cccs1
Show InChI InChI=1S/C17H15NO4S2/c1-21-13-5-4-11(10-15-16(19)18-17(20)24-15)9-14(13)22-7-6-12-3-2-8-23-12/h2-5,8-10H,6-7H2,1H3,(H,18,19,20)/b15-10-
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n/an/a 1.67E+3n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50049243
PNG
(5-[4-(1-Methyl-cyclohexylmethoxy)-benzyl]-thiazoli...)
Show SMILES CC1(COc2ccc(Cc3sc(=O)[nH]c3O)cc2)CCCCC1
Show InChI InChI=1S/C18H23NO3S/c1-18(9-3-2-4-10-18)12-22-14-7-5-13(6-8-14)11-15-16(20)19-17(21)23-15/h5-8,20H,2-4,9-12H2,1H3,(H,19,21)
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n/an/a 1.74E+3n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50378632
PNG
(CHEMBL601089 | US8637558, 25)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCc2ccco2)cc1 |w:7.8,t:1|
Show InChI InChI=1S/C15H11NO4S/c17-14-13(21-15(18)16-14)8-10-3-5-11(6-4-10)20-9-12-2-1-7-19-12/h1-8H,9H2,(H,16,17,18)
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n/an/a 1.88E+3n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118081
PNG
(US8637558, 118 | US8637558, 130)
Show SMILES Oc1[nH]c(=O)sc1Cc1ccc(OCCC2CCCC2)cc1
Show InChI InChI=1S/C17H21NO3S/c19-16-15(22-17(20)18-16)11-13-5-7-14(8-6-13)21-10-9-12-3-1-2-4-12/h5-8,12,19H,1-4,9-11H2,(H,18,20)
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n/an/a 2.21E+3n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118063
PNG
(US8637558, 96)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCC2CCCCC2)cc1Cl |w:7.8,t:1|
Show InChI InChI=1S/C17H18ClNO3S/c18-14-9-13(22-10-11-4-2-1-3-5-11)7-6-12(14)8-15-16(20)19-17(21)23-15/h6-9,11H,1-5,10H2,(H,19,20,21)
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n/an/a 2.45E+3n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118058
PNG
(US8637558, 90)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCN2CCS(=O)(=O)CC2)c(c1)[N+]([O-])=O |w:7.8,t:1|
Show InChI InChI=1S/C16H17N3O7S2/c20-15-14(27-16(21)17-15)10-11-1-2-13(12(9-11)19(22)23)26-6-3-18-4-7-28(24,25)8-5-18/h1-2,9-10H,3-8H2,(H,17,20,21)
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n/an/a 2.45E+3n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118011
PNG
(CHEMBL590503 | US8637558, 7)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCNC2CCCCC2)cc1 |w:7.8,t:1|
Show InChI InChI=1S/C18H22N2O3S/c21-17-16(24-18(22)20-17)12-13-6-8-15(9-7-13)23-11-10-19-14-4-2-1-3-5-14/h6-9,12,14,19H,1-5,10-11H2,(H,20,21,22)
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n/an/a 2.61E+3n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50438422
PNG
(CHEMBL2414141 | US8637558, 94)
Show SMILES CC(C)OCCOc1ccc(C=C2SC(O)=NC2=O)cc1Cl |w:11.10,c:15|
Show InChI InChI=1S/C15H16ClNO4S/c1-9(2)20-5-6-21-12-4-3-10(7-11(12)16)8-13-14(18)17-15(19)22-13/h3-4,7-9H,5-6H2,1-2H3,(H,17,18,19)
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n/an/a 2.74E+3n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118051
PNG
(US8637558, 79)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(c(OCCC2CCCCC2)c1)[N+]([O-])=O |w:7.8,t:1|
Show InChI InChI=1S/C18H20N2O5S/c21-17-16(26-18(22)19-17)11-13-6-7-14(20(23)24)15(10-13)25-9-8-12-4-2-1-3-5-12/h6-7,10-12H,1-5,8-9H2,(H,19,21,22)
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n/an/a 2.82E+3n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50378628
PNG
(CHEMBL599417 | US8637558, 21)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCCN2CCS(=O)(=O)CC2)cc1 |w:7.8,t:1|
Show InChI InChI=1S/C17H20N2O5S2/c20-16-15(25-17(21)18-16)12-13-2-4-14(5-3-13)24-9-1-6-19-7-10-26(22,23)11-8-19/h2-5,12H,1,6-11H2,(H,18,20,21)
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n/an/a 3.04E+3n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118037
PNG
(US8637558, 60)
Show SMILES COc1cc(OCCC2CCCCC2)ccc1C=C1SC(O)=NC1=O |w:17.18,c:23|
Show InChI InChI=1S/C19H23NO4S/c1-23-16-12-15(24-10-9-13-5-3-2-4-6-13)8-7-14(16)11-17-18(21)20-19(22)25-17/h7-8,11-13H,2-6,9-10H2,1H3,(H,20,21,22)
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n/an/a 3.56E+3n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50378633
PNG
(CHEMBL597377 | US8637558, 26)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCc2ccccn2)cc1 |w:7.8,t:1|
Show InChI InChI=1S/C16H12N2O3S/c19-15-14(22-16(20)18-15)9-11-4-6-13(7-5-11)21-10-12-3-1-2-8-17-12/h1-9H,10H2,(H,18,19,20)
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n/an/a 3.64E+3n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118078
PNG
(US8637558, 114)
Show SMILES Oc1[nH]c(=O)sc1Cc1ccc(OCC2CCCCC2)cc1
Show InChI InChI=1S/C17H21NO3S/c19-16-15(22-17(20)18-16)10-12-6-8-14(9-7-12)21-11-13-4-2-1-3-5-13/h6-9,13,19H,1-5,10-11H2,(H,18,20)
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n/an/a 4.06E+3n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118071
PNG
(US8637558, 106)
Show SMILES Cc1ncsc1CCOc1ccc(C=C2SC(O)=NC2=O)c(Cl)c1 |w:13.13,c:18|
Show InChI InChI=1S/C16H13ClN2O3S2/c1-9-13(23-8-18-9)4-5-22-11-3-2-10(12(17)7-11)6-14-15(20)19-16(21)24-14/h2-3,6-8H,4-5H2,1H3,(H,19,20,21)
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n/an/a 5.16E+3n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118082
PNG
(US8637558, 119 | US8637558, 126)
Show SMILES Oc1[nH]c(=O)sc1Cc1ccc(OCCN2CCS(=O)(=O)CC2)cc1
Show InChI InChI=1S/C16H22N2O5S2/c19-15-14(24-16(20)17-15)11-12-1-3-13(4-2-12)23-8-5-18-6-9-25(21,22)10-7-18/h1-4,9,19,21-22,25H,5-8,10-11H2,(H,17,20)
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n/an/a 5.21E+3n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50145471
PNG
(5-(4-(benzyloxy)benzyl)thiazolidine-2,4-dione | 5-...)
Show SMILES Oc1[nH]c(=O)sc1Cc1ccc(OCc2ccccc2)cc1
Show InChI InChI=1S/C17H15NO3S/c19-16-15(22-17(20)18-16)10-12-6-8-14(9-7-12)21-11-13-4-2-1-3-5-13/h1-9,19H,10-11H2,(H,18,20)
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n/an/a 5.25E+3n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118021
PNG
(US8637558, 40)
Show SMILES OCc1ccc(C=C2SC(O)=NC2=O)cc1 |w:6.5,c:10|
Show InChI InChI=1S/C11H9NO3S/c13-6-8-3-1-7(2-4-8)5-9-10(14)12-11(15)16-9/h1-5,13H,6H2,(H,12,14,15)
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n/an/a 5.67E+3n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM26623
PNG
((5Z)-5-[(4-methylphenyl)methylidene]-1,3-thiazolid...)
Show SMILES Cc1ccc(C=C2SC(O)=NC2=O)cc1 |w:5.4,c:9|
Show InChI InChI=1S/C11H9NO2S/c1-7-2-4-8(5-3-7)6-9-10(13)12-11(14)15-9/h2-6H,1H3,(H,12,13,14)
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n/an/a 5.82E+3n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118026
PNG
(US8637558, 48)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCCCC2CCCCC2)cc1 |w:7.8,t:1|
Show InChI InChI=1S/C20H25NO3S/c22-19-18(25-20(23)21-19)14-16-9-11-17(12-10-16)24-13-5-4-8-15-6-2-1-3-7-15/h9-12,14-15H,1-8,13H2,(H,21,22,23)
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n/an/a 6.01E+3n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118055
PNG
(US8637558, 83)
Show SMILES OC1=NC(=O)C(S1)=Cc1cc(OCCC2CCCCC2)ccc1[N+]([O-])=O |w:7.8,t:1|
Show InChI InChI=1S/C18H20N2O5S/c21-17-16(26-18(22)19-17)11-13-10-14(6-7-15(13)20(23)24)25-9-8-12-4-2-1-3-5-12/h6-7,10-12H,1-5,8-9H2,(H,19,21,22)
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n/an/a 6.28E+3n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM50438428
PNG
(CHEMBL2414242 | US8637558, 104)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCc2ccccn2)cc1Cl |w:7.8,t:1|
Show InChI InChI=1S/C17H13ClN2O3S/c18-14-10-13(23-8-6-12-3-1-2-7-19-12)5-4-11(14)9-15-16(21)20-17(22)24-15/h1-5,7,9-10H,6,8H2,(H,20,21,22)
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n/an/a 8.91E+3n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118076
PNG
(US8637558, 111)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCC2CCC(CC2)OC=O)cc1 |w:7.8,t:1,(8.38,-.79,;7.61,.54,;8.52,1.79,;7.61,3.04,;8.38,4.37,;6.15,2.56,;6.15,1.02,;4.82,3.33,;3.48,2.56,;3.48,1.02,;2.15,.25,;.82,1.02,;-.52,.25,;-1.85,1.02,;-3.19,.25,;-4.52,1.02,;-5.85,.25,;-5.85,-1.29,;-4.52,-2.06,;-3.19,-1.29,;-7.19,-2.06,;-8.52,-1.29,;-9.85,-2.06,;.82,2.56,;2.15,3.33,)|
Show InChI InChI=1S/C18H19NO5S/c20-11-24-15-7-3-13(4-8-15)10-23-14-5-1-12(2-6-14)9-16-17(21)19-18(22)25-16/h1-2,5-6,9,11,13,15H,3-4,7-8,10H2,(H,19,21,22)
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n/an/a 9.33E+3n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM60579
PNG
((5Z)-5-(4-hydroxybenzylidene)thiazolidine-2,4-quin...)
Show SMILES Oc1ccc(\C=C2/SC(=O)NC2=O)cc1
Show InChI InChI=1S/C10H7NO3S/c12-7-3-1-6(2-4-7)5-8-9(13)11-10(14)15-8/h1-5,12H,(H,11,13,14)/b8-5-
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n/an/a 1.01E+4n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118061
PNG
(US8637558, 93)
Show SMILES OC1=NC(=O)C(S1)=Cc1cccc(OCCc2ccccn2)c1Cl |w:7.8,t:1|
Show InChI InChI=1S/C17H13ClN2O3S/c18-15-11(10-14-16(21)20-17(22)24-14)4-3-6-13(15)23-9-7-12-5-1-2-8-19-12/h1-6,8,10H,7,9H2,(H,20,21,22)
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n/an/a 1.03E+4n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118074
PNG
(US8637558, 109)
Show SMILES OC1=NC(=O)C(S1)=Cc1cccc(OCc2ccc(cc2)[N+]([O-])=O)c1Cl |w:7.8,t:1|
Show InChI InChI=1S/C17H11ClN2O5S/c18-15-11(8-14-16(21)19-17(22)26-14)2-1-3-13(15)25-9-10-4-6-12(7-5-10)20(23)24/h1-8H,9H2,(H,19,21,22)
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n/an/a 1.17E+4n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)]


(Homo sapiens (Human))
BDBM118032
PNG
(US8637558, 54)
Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(Oc2ccccc2)cc1 |w:7.8,t:1|
Show InChI InChI=1S/C16H11NO3S/c18-15-14(21-16(19)17-15)10-11-6-8-13(9-7-11)20-12-4-2-1-3-5-12/h1-10H,(H,17,18,19)
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n/an/a 2.00E+4n/an/an/an/a7.5n/a



Industry-Academic Cooperation Foundation, Chosun University

US Patent


Assay Description
Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...


US Patent US8637558 (2014)


BindingDB Entry DOI: 10.7270/Q280519F
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%