Found 23 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Neuropeptide Y receptor type 5
(Mus musculus (Mouse)) | BDBM118179
(US8653125, Ia-40)Show SMILES Clc1ccc(cc1Cl)-c1c[nH]c(n1)[C@@H]1CC[C@@H](CC1)NC(=O)c1ccon1 |r,wU:16.21,13.14,(9.04,-4.47,;7.7,-3.7,;6.37,-4.47,;5.04,-3.7,;5.04,-2.16,;6.37,-1.39,;7.7,-2.16,;9.04,-1.39,;3.7,-1.39,;3.7,.15,;2.24,.62,;1.33,-.62,;2.24,-1.87,;,.15,;,1.69,;-1.33,2.46,;-2.67,1.69,;-2.67,.15,;-1.33,-.62,;-4,2.46,;-5.33,1.69,;-5.33,.15,;-6.67,2.46,;-8.13,1.98,;-9.04,3.23,;-8.13,4.47,;-6.67,4,)| Show InChI InChI=1S/C19H18Cl2N4O2/c20-14-6-3-12(9-15(14)21)17-10-22-18(24-17)11-1-4-13(5-2-11)23-19(26)16-7-8-27-25-16/h3,6-11,13H,1-2,4-5H2,(H,22,24)(H,23,26)/t11-,13+ | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 0.260 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Shionogi Co., Ltd.
US Patent
| Assay Description
cDNA sequence encoding mouse NPY Y5 receptor (Biochem. Biophys. Acta 1328: 83-89, 1997) was cloned in the expression vector (pME18S, Takebe et al. Mo... |
US Patent US8653125 (2014)
BindingDB Entry DOI: 10.7270/Q2VQ31BN |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Mus musculus (Mouse)) | BDBM118190
(US8653125, Ic-16)Show SMILES CC(C)n1c2ccc(NC(=O)[C@@H]3CC[C@@H](CC3)Oc3cc(ccn3)C(F)(F)F)cc2oc1=O |r,wU:14.17,11.10,(6.26,-3.84,;7.35,-2.75,;8.83,-3.15,;6.95,-1.26,;5.48,-.78,;4.15,-1.55,;2.82,-.78,;2.82,.76,;1.48,1.53,;.15,.76,;.15,-.78,;-1.18,1.53,;-1.18,3.07,;-2.52,3.84,;-3.85,3.07,;-3.85,1.53,;-2.52,.76,;-5.19,3.84,;-6.52,3.07,;-6.52,1.53,;-7.85,.76,;-9.19,1.53,;-9.19,3.07,;-7.85,3.84,;-7.85,-.78,;-7.85,-2.32,;-9.39,-.78,;-6.31,-.78,;4.15,1.53,;5.48,.76,;6.95,1.23,;7.85,-.01,;9.39,-.01,)| Show InChI InChI=1S/C23H24F3N3O4/c1-13(2)29-18-8-5-16(12-19(18)33-22(29)31)28-21(30)14-3-6-17(7-4-14)32-20-11-15(9-10-27-20)23(24,25)26/h5,8-14,17H,3-4,6-7H2,1-2H3,(H,28,30)/t14-,17+ | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.410 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Shionogi Co., Ltd.
US Patent
| Assay Description
cDNA sequence encoding mouse NPY Y5 receptor (Biochem. Biophys. Acta 1328: 83-89, 1997) was cloned in the expression vector (pME18S, Takebe et al. Mo... |
US Patent US8653125 (2014)
BindingDB Entry DOI: 10.7270/Q2VQ31BN |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Mus musculus (Mouse)) | BDBM118188
(US8653125, Ic-13)Show SMILES CC(C)n1c2ccc(NC(=O)[C@@H]3CC[C@@H](CC3)Oc3cc(Cl)ccc3C#N)cc2oc1=O |r,wU:14.17,11.10,(6.15,-5.38,;7.24,-4.29,;8.73,-4.69,;6.84,-2.8,;5.38,-2.32,;4.05,-3.09,;2.71,-2.32,;2.71,-.78,;1.38,-.01,;.05,-.78,;.05,-2.32,;-1.29,-.01,;-1.29,1.53,;-2.62,2.3,;-3.96,1.53,;-3.96,-.01,;-2.62,-.78,;-5.29,2.3,;-6.62,1.53,;-6.62,-.01,;-7.96,-.78,;-7.96,-2.32,;-9.29,-.01,;-9.29,1.53,;-7.96,2.3,;-7.96,3.84,;-7.96,5.38,;4.05,-.01,;5.38,-.78,;6.84,-.31,;7.75,-1.55,;9.29,-1.55,)| Show InChI InChI=1S/C24H24ClN3O4/c1-14(2)28-20-10-7-18(12-22(20)32-24(28)30)27-23(29)15-4-8-19(9-5-15)31-21-11-17(25)6-3-16(21)13-26/h3,6-7,10-12,14-15,19H,4-5,8-9H2,1-2H3,(H,27,29)/t15-,19+ | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 0.560 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Shionogi Co., Ltd.
US Patent
| Assay Description
cDNA sequence encoding mouse NPY Y5 receptor (Biochem. Biophys. Acta 1328: 83-89, 1997) was cloned in the expression vector (pME18S, Takebe et al. Mo... |
US Patent US8653125 (2014)
BindingDB Entry DOI: 10.7270/Q2VQ31BN |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Mus musculus (Mouse)) | BDBM118192
(US8653125, Id-8)Show SMILES Fc1ccccc1-n1ccc(NC(=O)[C@@H]2CC[C@@H](CC2)N2c3ccccc3OS2(=O)=O)n1 |r,wU:17.21,14.14,(6.68,-.13,;7.45,-1.46,;8.99,-1.46,;9.76,-2.8,;8.99,-4.13,;7.45,-4.13,;6.68,-2.8,;5.14,-2.8,;4.23,-4.04,;2.77,-3.57,;2.77,-2.03,;1.44,-1.26,;.1,-2.03,;.1,-3.57,;-1.23,-1.26,;-1.23,.28,;-2.56,1.05,;-3.9,.28,;-3.9,-1.26,;-2.56,-2.03,;-5.23,1.05,;-6.7,.58,;-7.32,-.83,;-8.85,-.99,;-9.76,.25,;-9.13,1.66,;-7.6,1.82,;-6.7,3.07,;-5.23,2.59,;-5.23,4.13,;-3.69,2.59,;4.23,-1.55,)| Show InChI InChI=1S/C22H21FN4O4S/c23-17-5-1-2-6-18(17)26-14-13-21(25-26)24-22(28)15-9-11-16(12-10-15)27-19-7-3-4-8-20(19)31-32(27,29)30/h1-8,13-16H,9-12H2,(H,24,25,28)/t15-,16+ | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.580 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Shionogi Co., Ltd.
US Patent
| Assay Description
cDNA sequence encoding mouse NPY Y5 receptor (Biochem. Biophys. Acta 1328: 83-89, 1997) was cloned in the expression vector (pME18S, Takebe et al. Mo... |
US Patent US8653125 (2014)
BindingDB Entry DOI: 10.7270/Q2VQ31BN |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Mus musculus (Mouse)) | BDBM118178
(US8653125, Ia-35)Show SMILES O=C(Nc1ccc(cc1)-c1ccccc1)[C@@H]1CC[C@@H](CC1)NC(=O)c1ccon1 |r,wU:18.23,15.16,(.52,-1.78,;.52,-.24,;1.85,.53,;3.19,-.24,;3.19,-1.78,;4.52,-2.55,;5.85,-1.78,;5.85,-.24,;4.52,.53,;7.19,-2.55,;7.19,-4.09,;8.52,-4.86,;9.85,-4.09,;9.85,-2.55,;8.52,-1.78,;-.82,.53,;-.82,2.07,;-2.15,2.84,;-3.48,2.07,;-3.48,.53,;-2.15,-.24,;-4.82,2.84,;-6.15,2.07,;-6.15,.53,;-7.48,2.84,;-8.95,2.37,;-9.85,3.61,;-8.95,4.86,;-7.48,4.38,)| Show InChI InChI=1S/C23H23N3O3/c27-22(24-19-10-6-17(7-11-19)16-4-2-1-3-5-16)18-8-12-20(13-9-18)25-23(28)21-14-15-29-26-21/h1-7,10-11,14-15,18,20H,8-9,12-13H2,(H,24,27)(H,25,28)/t18-,20+ | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 0.650 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Shionogi Co., Ltd.
US Patent
| Assay Description
cDNA sequence encoding mouse NPY Y5 receptor (Biochem. Biophys. Acta 1328: 83-89, 1997) was cloned in the expression vector (pME18S, Takebe et al. Mo... |
US Patent US8653125 (2014)
BindingDB Entry DOI: 10.7270/Q2VQ31BN |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Mus musculus (Mouse)) | BDBM118189
(US8653125, Ic-14)Show SMILES CC(C)n1c2ccc(NC(=O)[C@@H]3CC[C@@H](CC3)Oc3cc(ccc3C#N)C(F)(F)F)cc2oc1=O |r,wU:14.17,11.10,(6.26,-5.38,;7.35,-4.29,;8.83,-4.69,;6.95,-2.8,;5.48,-2.32,;4.15,-3.09,;2.82,-2.32,;2.82,-.78,;1.48,-.01,;.15,-.78,;.15,-2.32,;-1.18,-.01,;-1.18,1.53,;-2.52,2.3,;-3.85,1.53,;-3.85,-.01,;-2.52,-.78,;-5.19,2.3,;-6.52,1.53,;-6.52,-.01,;-7.85,-.78,;-9.19,-.01,;-9.19,1.53,;-7.85,2.3,;-7.85,3.84,;-7.85,5.38,;-7.85,-2.32,;-7.85,-3.86,;-9.39,-2.32,;-6.31,-2.32,;4.15,-.01,;5.48,-.78,;6.95,-.31,;7.85,-1.55,;9.39,-1.55,)| Show InChI InChI=1S/C25H24F3N3O4/c1-14(2)31-20-10-7-18(12-22(20)35-24(31)33)30-23(32)15-4-8-19(9-5-15)34-21-11-17(25(26,27)28)6-3-16(21)13-29/h3,6-7,10-12,14-15,19H,4-5,8-9H2,1-2H3,(H,30,32)/t15-,19+ | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 0.680 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Shionogi Co., Ltd.
US Patent
| Assay Description
cDNA sequence encoding mouse NPY Y5 receptor (Biochem. Biophys. Acta 1328: 83-89, 1997) was cloned in the expression vector (pME18S, Takebe et al. Mo... |
US Patent US8653125 (2014)
BindingDB Entry DOI: 10.7270/Q2VQ31BN |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Mus musculus (Mouse)) | BDBM118191
(US8653125, Ic-17)Show SMILES Fc1ccccc1-n1ccc(NC(=O)[C@@H]2CC[C@@H](CC2)Oc2cc(Cl)ccn2)n1 |r,wU:17.21,14.14,(6.42,1.41,;7.19,.08,;8.73,.08,;9.5,-1.26,;8.73,-2.59,;7.19,-2.59,;6.42,-1.26,;4.88,-1.26,;3.97,-2.5,;2.51,-2.03,;2.51,-.49,;1.17,.28,;-.16,-.49,;-.16,-2.03,;-1.49,.28,;-1.49,1.82,;-2.83,2.59,;-4.16,1.82,;-4.16,.28,;-2.83,-.49,;-5.5,2.59,;-6.83,1.82,;-6.83,.28,;-8.16,-.49,;-8.16,-2.03,;-9.5,.28,;-9.5,1.82,;-8.16,2.59,;3.97,-.01,)| Show InChI InChI=1S/C21H20ClFN4O2/c22-15-9-11-24-20(13-15)29-16-7-5-14(6-8-16)21(28)25-19-10-12-27(26-19)18-4-2-1-3-17(18)23/h1-4,9-14,16H,5-8H2,(H,25,26,28)/t14-,16+ | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.690 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Shionogi Co., Ltd.
US Patent
| Assay Description
cDNA sequence encoding mouse NPY Y5 receptor (Biochem. Biophys. Acta 1328: 83-89, 1997) was cloned in the expression vector (pME18S, Takebe et al. Mo... |
US Patent US8653125 (2014)
BindingDB Entry DOI: 10.7270/Q2VQ31BN |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Mus musculus (Mouse)) | BDBM118176
(US8653125, Ia-30)Show SMILES Fc1ccccc1-c1ccc(NC(=O)[C@@H]2CC[C@@H](CC2)NC(=O)c2ccon2)cc1 |r,wU:17.21,14.14,(8.52,-.24,;8.52,-1.78,;9.85,-2.55,;9.85,-4.09,;8.52,-4.86,;7.19,-4.09,;7.19,-2.55,;5.85,-1.78,;4.52,-2.55,;3.19,-1.78,;3.19,-.24,;1.85,.53,;.52,-.24,;.52,-1.78,;-.82,.53,;-.82,2.07,;-2.15,2.84,;-3.48,2.07,;-3.48,.53,;-2.15,-.24,;-4.82,2.84,;-6.15,2.07,;-6.15,.53,;-7.48,2.84,;-8.95,2.37,;-9.85,3.61,;-8.95,4.86,;-7.48,4.38,;4.52,.53,;5.85,-.24,)| Show InChI InChI=1S/C23H22FN3O3/c24-20-4-2-1-3-19(20)15-5-9-17(10-6-15)25-22(28)16-7-11-18(12-8-16)26-23(29)21-13-14-30-27-21/h1-6,9-10,13-14,16,18H,7-8,11-12H2,(H,25,28)(H,26,29)/t16-,18+ | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 0.710 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Shionogi Co., Ltd.
US Patent
| Assay Description
cDNA sequence encoding mouse NPY Y5 receptor (Biochem. Biophys. Acta 1328: 83-89, 1997) was cloned in the expression vector (pME18S, Takebe et al. Mo... |
US Patent US8653125 (2014)
BindingDB Entry DOI: 10.7270/Q2VQ31BN |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Mus musculus (Mouse)) | BDBM118187
(US8653125, Ic-12)Show SMILES C[C@H]1CN(C[C@@H](C)O1)c1ccc(NC(=O)[C@@H]2CC[C@@H](CC2)Oc2cc(Cl)ccc2C#N)cc1 |r,wU:18.22,15.15,1.0,5.5,(7.34,-6.16,;7.34,-4.62,;6,-3.85,;6,-2.31,;7.34,-1.54,;8.67,-2.31,;10,-1.54,;8.67,-3.85,;4.67,-1.54,;3.33,-2.31,;2,-1.54,;2,,;.67,.77,;-.67,,;-.67,-1.54,;-2,.77,;-2,2.31,;-3.33,3.08,;-4.67,2.31,;-4.67,.77,;-3.33,,;-6,3.08,;-7.34,2.31,;-7.34,.77,;-8.67,,;-8.67,-1.54,;-10,.77,;-10,2.31,;-8.67,3.08,;-8.67,4.62,;-8.67,6.16,;3.33,.77,;4.67,,)| Show InChI InChI=1S/C26H30ClN3O3/c1-17-15-30(16-18(2)32-17)23-9-7-22(8-10-23)29-26(31)19-4-11-24(12-5-19)33-25-13-21(27)6-3-20(25)14-28/h3,6-10,13,17-19,24H,4-5,11-12,15-16H2,1-2H3,(H,29,31)/t17-,18+,19-,24+ | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Shionogi Co., Ltd.
US Patent
| Assay Description
cDNA sequence encoding mouse NPY Y5 receptor (Biochem. Biophys. Acta 1328: 83-89, 1997) was cloned in the expression vector (pME18S, Takebe et al. Mo... |
US Patent US8653125 (2014)
BindingDB Entry DOI: 10.7270/Q2VQ31BN |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Mus musculus (Mouse)) | BDBM118183
(US8653125, Ib-4)Show SMILES CC(C)n1c2ccc(NC(=O)[C@@H]3CC[C@@H](CC3)Nc3cccc(F)n3)cc2oc1=O |r,wU:14.17,11.10,(6.82,-3.84,;7.91,-2.75,;9.4,-3.15,;7.51,-1.26,;6.05,-.78,;4.71,-1.55,;3.38,-.78,;3.38,.76,;2.05,1.53,;.71,.76,;.71,-.78,;-.62,1.53,;-.62,3.07,;-1.95,3.84,;-3.29,3.07,;-3.29,1.53,;-1.95,.76,;-4.62,3.84,;-5.96,3.07,;-5.96,1.53,;-7.29,.76,;-8.62,1.53,;-8.62,3.07,;-9.96,3.84,;-7.29,3.84,;4.71,1.53,;6.05,.76,;7.51,1.23,;8.42,-.01,;9.96,-.01,)| Show InChI InChI=1S/C22H25FN4O3/c1-13(2)27-17-11-10-16(12-18(17)30-22(27)29)25-21(28)14-6-8-15(9-7-14)24-20-5-3-4-19(23)26-20/h3-5,10-15H,6-9H2,1-2H3,(H,24,26)(H,25,28)/t14-,15+ | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Shionogi Co., Ltd.
US Patent
| Assay Description
cDNA sequence encoding mouse NPY Y5 receptor (Biochem. Biophys. Acta 1328: 83-89, 1997) was cloned in the expression vector (pME18S, Takebe et al. Mo... |
US Patent US8653125 (2014)
BindingDB Entry DOI: 10.7270/Q2VQ31BN |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Mus musculus (Mouse)) | BDBM118184
(US8653125, Ic-5)Show SMILES C[C@H]1CN(C[C@@H](C)O1)c1ccc(NC(=O)[C@@H]2CC[C@@H](CC2)Oc2cc(Cl)ccn2)cc1 |r,wU:18.22,15.15,5.5,1.0,(7.34,-4.62,;7.34,-3.08,;6,-2.31,;6,-.77,;7.34,,;8.67,-.77,;10,,;8.67,-2.31,;4.67,,;3.33,-.77,;2,,;2,1.54,;.67,2.31,;-.67,1.54,;-.67,,;-2,2.31,;-2,3.85,;-3.33,4.62,;-4.67,3.85,;-4.67,2.31,;-3.33,1.54,;-6,4.62,;-7.34,3.85,;-7.34,2.31,;-8.67,1.54,;-8.67,,;-10,2.31,;-10,3.85,;-8.67,4.62,;3.33,2.31,;4.67,1.54,)| Show InChI InChI=1S/C24H30ClN3O3/c1-16-14-28(15-17(2)30-16)21-7-5-20(6-8-21)27-24(29)18-3-9-22(10-4-18)31-23-13-19(25)11-12-26-23/h5-8,11-13,16-18,22H,3-4,9-10,14-15H2,1-2H3,(H,27,29)/t16-,17+,18-,22+ | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Shionogi Co., Ltd.
US Patent
| Assay Description
cDNA sequence encoding mouse NPY Y5 receptor (Biochem. Biophys. Acta 1328: 83-89, 1997) was cloned in the expression vector (pME18S, Takebe et al. Mo... |
US Patent US8653125 (2014)
BindingDB Entry DOI: 10.7270/Q2VQ31BN |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Mus musculus (Mouse)) | BDBM118170
(US8653125, Ia-2)Show SMILES Fc1cccc(n1)C(=O)N[C@H]1CC[C@H](CC1)C(=O)Nc1ccn(n1)-c1ccccc1F |r,wU:10.10,13.17,(-8.83,4.52,;-8.83,2.98,;-10.16,2.21,;-10.16,.67,;-8.83,-.1,;-7.5,.67,;-7.5,2.21,;-6.16,-.1,;-6.16,-1.64,;-4.83,.67,;-3.49,-.1,;-2.16,.67,;-.83,-.1,;-.83,-1.64,;-2.16,-2.41,;-3.49,-1.64,;.51,-2.41,;.51,-3.95,;1.84,-1.64,;3.17,-2.41,;3.17,-3.95,;4.64,-4.43,;5.54,-3.18,;4.64,-1.94,;7.08,-3.18,;7.85,-4.52,;9.39,-4.52,;10.16,-3.18,;9.39,-1.85,;7.85,-1.85,;7.08,-.52,)| Show InChI InChI=1S/C22H21F2N5O2/c23-16-4-1-2-6-18(16)29-13-12-20(28-29)27-21(30)14-8-10-15(11-9-14)25-22(31)17-5-3-7-19(24)26-17/h1-7,12-15H,8-11H2,(H,25,31)(H,27,28,30)/t14-,15+ | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Shionogi Co., Ltd.
US Patent
| Assay Description
cDNA sequence encoding mouse NPY Y5 receptor (Biochem. Biophys. Acta 1328: 83-89, 1997) was cloned in the expression vector (pME18S, Takebe et al. Mo... |
US Patent US8653125 (2014)
BindingDB Entry DOI: 10.7270/Q2VQ31BN |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Mus musculus (Mouse)) | BDBM118181
(US8653125, Ia-43)Show SMILES FC(F)(F)c1cccc(c1)-c1c[nH]c(n1)[C@@H]1CC[C@@H](CC1)NC(=O)c1ccon1 |r,wU:18.23,15.16,(9.7,-.62,;8.37,-1.39,;9.14,-2.73,;7.6,-.06,;7.04,-2.16,;7.04,-3.7,;5.7,-4.47,;4.37,-3.7,;4.37,-2.16,;5.7,-1.39,;3.04,-1.39,;3.04,.15,;1.57,.62,;.67,-.62,;1.57,-1.87,;-.67,.15,;-.67,1.69,;-2,2.46,;-3.33,1.69,;-3.33,.15,;-2,-.62,;-4.67,2.46,;-6,1.69,;-6,.15,;-7.34,2.46,;-8.8,1.98,;-9.7,3.23,;-8.8,4.47,;-7.34,4,)| Show InChI InChI=1S/C20H19F3N4O2/c21-20(22,23)14-3-1-2-13(10-14)17-11-24-18(26-17)12-4-6-15(7-5-12)25-19(28)16-8-9-29-27-16/h1-3,8-12,15H,4-7H2,(H,24,26)(H,25,28)/t12-,15+ | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Shionogi Co., Ltd.
US Patent
| Assay Description
cDNA sequence encoding mouse NPY Y5 receptor (Biochem. Biophys. Acta 1328: 83-89, 1997) was cloned in the expression vector (pME18S, Takebe et al. Mo... |
US Patent US8653125 (2014)
BindingDB Entry DOI: 10.7270/Q2VQ31BN |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Mus musculus (Mouse)) | BDBM118186
(US8653125, Ic-11)Show SMILES C[C@H]1CN(C[C@@H](C)O1)c1ccc(NC(=O)[C@@H]2CC[C@@H](CC2)Oc2cc(ccc2C#N)C(F)(F)F)cc1 |r,wU:18.22,15.15,1.0,5.5,(7.44,-6.16,;7.44,-4.62,;6.1,-3.85,;6.1,-2.31,;7.44,-1.54,;8.77,-2.31,;10.11,-1.54,;8.77,-3.85,;4.77,-1.54,;3.44,-2.31,;2.1,-1.54,;2.1,,;.77,.77,;-.56,,;-.56,-1.54,;-1.9,.77,;-1.9,2.31,;-3.23,3.08,;-4.56,2.31,;-4.56,.77,;-3.23,,;-5.9,3.08,;-7.23,2.31,;-7.23,.77,;-8.57,,;-9.9,.77,;-9.9,2.31,;-8.57,3.08,;-8.57,4.62,;-8.57,6.16,;-8.57,-1.54,;-8.57,-3.08,;-10.11,-1.54,;-7.03,-1.54,;3.44,.77,;4.77,,)| Show InChI InChI=1S/C27H30F3N3O3/c1-17-15-33(16-18(2)35-17)23-9-7-22(8-10-23)32-26(34)19-4-11-24(12-5-19)36-25-13-21(27(28,29)30)6-3-20(25)14-31/h3,6-10,13,17-19,24H,4-5,11-12,15-16H2,1-2H3,(H,32,34)/t17-,18+,19-,24+ | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Shionogi Co., Ltd.
US Patent
| Assay Description
cDNA sequence encoding mouse NPY Y5 receptor (Biochem. Biophys. Acta 1328: 83-89, 1997) was cloned in the expression vector (pME18S, Takebe et al. Mo... |
US Patent US8653125 (2014)
BindingDB Entry DOI: 10.7270/Q2VQ31BN |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Mus musculus (Mouse)) | BDBM118185
(US8653125, Ic-8)Show SMILES FC(F)Oc1ccc(NC(=O)[C@@H]2CC[C@@H](CC2)Oc2ccccc2C#N)cc1 |r,wU:14.17,11.10,(9.34,-4.23,;8,-3.47,;8,-1.93,;6.67,-4.23,;5.33,-3.46,;4,-4.23,;2.67,-3.46,;2.67,-1.93,;1.33,-1.15,;,-1.93,;,-3.47,;-1.33,-1.15,;-1.33,.38,;-2.67,1.15,;-4,.38,;-4,-1.15,;-2.67,-1.93,;-5.33,1.15,;-6.67,.38,;-6.67,-1.15,;-8,-1.92,;-9.34,-1.15,;-9.34,.38,;-8,1.15,;-8,2.69,;-8,4.23,;4,-1.15,;5.33,-1.93,)| Show InChI InChI=1S/C21H20F2N2O3/c22-21(23)28-18-11-7-16(8-12-18)25-20(26)14-5-9-17(10-6-14)27-19-4-2-1-3-15(19)13-24/h1-4,7-8,11-12,14,17,21H,5-6,9-10H2,(H,25,26)/t14-,17+ | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Shionogi Co., Ltd.
US Patent
| Assay Description
cDNA sequence encoding mouse NPY Y5 receptor (Biochem. Biophys. Acta 1328: 83-89, 1997) was cloned in the expression vector (pME18S, Takebe et al. Mo... |
US Patent US8653125 (2014)
BindingDB Entry DOI: 10.7270/Q2VQ31BN |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Mus musculus (Mouse)) | BDBM118182
(US8653125, Ib-1)Show SMILES Fc1cccc(N[C@H]2CC[C@H](CC2)C(=O)Nc2ccn(n2)-c2ccccc2F)n1 |r,wU:7.6,10.13,(-10.16,2.59,;-8.83,1.82,;-8.83,.28,;-7.5,-.49,;-6.16,.28,;-6.16,1.82,;-4.83,2.59,;-3.49,1.82,;-2.16,2.59,;-.83,1.82,;-.83,.28,;-2.16,-.49,;-3.49,.28,;.51,-.49,;.51,-2.03,;1.84,.28,;3.17,-.49,;3.17,-2.03,;4.64,-2.5,;5.54,-1.26,;4.64,-.01,;7.08,-1.26,;7.85,-2.59,;9.39,-2.59,;10.16,-1.26,;9.39,.08,;7.85,.08,;7.08,1.41,;-7.5,2.59,)| Show InChI InChI=1S/C21H21F2N5O/c22-16-4-1-2-5-17(16)28-13-12-20(27-28)26-21(29)14-8-10-15(11-9-14)24-19-7-3-6-18(23)25-19/h1-7,12-15H,8-11H2,(H,24,25)(H,26,27,29)/t14-,15+ | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Shionogi Co., Ltd.
US Patent
| Assay Description
cDNA sequence encoding mouse NPY Y5 receptor (Biochem. Biophys. Acta 1328: 83-89, 1997) was cloned in the expression vector (pME18S, Takebe et al. Mo... |
US Patent US8653125 (2014)
BindingDB Entry DOI: 10.7270/Q2VQ31BN |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Mus musculus (Mouse)) | BDBM118174
(US8653125, Ia-24)Show SMILES Fc1ccccc1-n1ccc(NC(=O)[C@@H]2CC[C@@H](CC2)NC(=O)c2ccccc2C#N)n1 |r,wU:17.21,14.14,(7.08,-.13,;7.85,-1.46,;9.39,-1.46,;10.16,-2.8,;9.39,-4.13,;7.85,-4.13,;7.08,-2.8,;5.54,-2.8,;4.64,-4.04,;3.17,-3.57,;3.17,-2.03,;1.84,-1.26,;.51,-2.03,;.51,-3.57,;-.83,-1.26,;-.83,.28,;-2.16,1.05,;-3.49,.28,;-3.49,-1.26,;-2.16,-2.03,;-4.83,1.05,;-6.16,.28,;-6.16,-1.26,;-7.5,1.05,;-8.83,.28,;-10.16,1.05,;-10.16,2.59,;-8.83,3.36,;-7.5,2.59,;-6.16,3.36,;-4.83,4.13,;4.64,-1.55,)| Show InChI InChI=1S/C24H22FN5O2/c25-20-7-3-4-8-21(20)30-14-13-22(29-30)28-23(31)16-9-11-18(12-10-16)27-24(32)19-6-2-1-5-17(19)15-26/h1-8,13-14,16,18H,9-12H2,(H,27,32)(H,28,29,31)/t16-,18+ | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Shionogi Co., Ltd.
US Patent
| Assay Description
cDNA sequence encoding mouse NPY Y5 receptor (Biochem. Biophys. Acta 1328: 83-89, 1997) was cloned in the expression vector (pME18S, Takebe et al. Mo... |
US Patent US8653125 (2014)
BindingDB Entry DOI: 10.7270/Q2VQ31BN |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Mus musculus (Mouse)) | BDBM118180
(US8653125, Ia-42)Show SMILES Clc1cccc(c1)-c1c[nH]c(n1)[C@@H]1CC[C@@H](CC1)NC(=O)c1ccon1 |r,wU:15.20,12.13,(9.04,-1.39,;7.7,-2.16,;7.7,-3.7,;6.37,-4.47,;5.04,-3.7,;5.04,-2.16,;6.37,-1.39,;3.7,-1.39,;3.7,.15,;2.24,.62,;1.33,-.62,;2.24,-1.87,;,.15,;,1.69,;-1.33,2.46,;-2.67,1.69,;-2.67,.15,;-1.33,-.62,;-4,2.46,;-5.33,1.69,;-5.33,.15,;-6.67,2.46,;-8.13,1.98,;-9.04,3.23,;-8.13,4.47,;-6.67,4,)| Show InChI InChI=1S/C19H19ClN4O2/c20-14-3-1-2-13(10-14)17-11-21-18(23-17)12-4-6-15(7-5-12)22-19(25)16-8-9-26-24-16/h1-3,8-12,15H,4-7H2,(H,21,23)(H,22,25)/t12-,15+ | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Shionogi Co., Ltd.
US Patent
| Assay Description
cDNA sequence encoding mouse NPY Y5 receptor (Biochem. Biophys. Acta 1328: 83-89, 1997) was cloned in the expression vector (pME18S, Takebe et al. Mo... |
US Patent US8653125 (2014)
BindingDB Entry DOI: 10.7270/Q2VQ31BN |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Mus musculus (Mouse)) | BDBM118177
(US8653125, Ia-32)Show SMILES CC(C)n1c2ccc(NC(=O)[C@@H]3CC[C@@H](CC3)NC(=O)c3ccon3)cc2oc1=O |r,wU:14.17,11.10,(6.67,-4.84,;7.76,-3.76,;9.25,-4.15,;7.36,-2.27,;5.9,-1.79,;4.56,-2.56,;3.23,-1.79,;3.23,-.25,;1.9,.52,;.56,-.25,;.56,-1.79,;-.77,.52,;-.77,2.06,;-2.1,2.83,;-3.44,2.06,;-3.44,.52,;-2.1,-.25,;-4.77,2.83,;-6.1,2.06,;-6.1,.52,;-7.44,2.83,;-8.9,2.35,;-9.81,3.6,;-8.9,4.84,;-7.44,4.37,;4.56,.52,;5.9,-.25,;7.36,.22,;8.27,-1.02,;9.81,-1.02,)| Show InChI InChI=1S/C21H24N4O5/c1-12(2)25-17-8-7-15(11-18(17)30-21(25)28)23-19(26)13-3-5-14(6-4-13)22-20(27)16-9-10-29-24-16/h7-14H,3-6H2,1-2H3,(H,22,27)(H,23,26)/t13-,14+ | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 3.30 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Shionogi Co., Ltd.
US Patent
| Assay Description
cDNA sequence encoding mouse NPY Y5 receptor (Biochem. Biophys. Acta 1328: 83-89, 1997) was cloned in the expression vector (pME18S, Takebe et al. Mo... |
US Patent US8653125 (2014)
BindingDB Entry DOI: 10.7270/Q2VQ31BN |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Mus musculus (Mouse)) | BDBM118171
(US8653125, Ia-4)Show SMILES Fc1ccccc1-n1ccc(NC(=O)[C@@H]2CC[C@@H](CC2)NC(=O)c2cccc(Cl)n2)n1 |r,wU:17.21,14.14,(7.08,-.52,;7.85,-1.85,;9.39,-1.85,;10.16,-3.18,;9.39,-4.52,;7.85,-4.52,;7.08,-3.18,;5.54,-3.18,;4.64,-4.43,;3.17,-3.95,;3.17,-2.41,;1.84,-1.64,;.51,-2.41,;.51,-3.95,;-.83,-1.64,;-.83,-.1,;-2.16,.67,;-3.49,-.1,;-3.49,-1.64,;-2.16,-2.41,;-4.83,.67,;-6.16,-.1,;-6.16,-1.64,;-7.5,.67,;-8.83,-.1,;-10.16,.67,;-10.16,2.21,;-8.83,2.98,;-8.83,4.52,;-7.5,2.21,;4.64,-1.94,)| Show InChI InChI=1S/C22H21ClFN5O2/c23-19-7-3-5-17(26-19)22(31)25-15-10-8-14(9-11-15)21(30)27-20-12-13-29(28-20)18-6-2-1-4-16(18)24/h1-7,12-15H,8-11H2,(H,25,31)(H,27,28,30)/t14-,15+ | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Shionogi Co., Ltd.
US Patent
| Assay Description
cDNA sequence encoding mouse NPY Y5 receptor (Biochem. Biophys. Acta 1328: 83-89, 1997) was cloned in the expression vector (pME18S, Takebe et al. Mo... |
US Patent US8653125 (2014)
BindingDB Entry DOI: 10.7270/Q2VQ31BN |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Mus musculus (Mouse)) | BDBM118172
(US8653125, Ia-14)Show SMILES Fc1ccccc1-c1cccc(NC(=O)[C@@H]2CC[C@@H](CC2)NC(=O)c2ccccc2)c1 |r,wU:18.22,15.15,(8.67,-3.08,;8.67,-1.54,;10,-.77,;10,.77,;8.67,1.54,;7.34,.77,;7.34,-.77,;6,-1.54,;6,-3.08,;4.67,-3.85,;3.33,-3.08,;3.33,-1.54,;2,-.77,;.67,-1.54,;.67,-3.08,;-.67,-.77,;-.67,.77,;-2,1.54,;-3.33,.77,;-3.33,-.77,;-2,-1.54,;-4.67,1.54,;-6,.77,;-6,-.77,;-7.34,1.54,;-8.67,.77,;-10,1.54,;-10,3.08,;-8.67,3.85,;-7.34,3.08,;4.67,-.77,)| Show InChI InChI=1S/C26H25FN2O2/c27-24-12-5-4-11-23(24)20-9-6-10-22(17-20)29-26(31)19-13-15-21(16-14-19)28-25(30)18-7-2-1-3-8-18/h1-12,17,19,21H,13-16H2,(H,28,30)(H,29,31)/t19-,21+ | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 4.10 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Shionogi Co., Ltd.
US Patent
| Assay Description
cDNA sequence encoding mouse NPY Y5 receptor (Biochem. Biophys. Acta 1328: 83-89, 1997) was cloned in the expression vector (pME18S, Takebe et al. Mo... |
US Patent US8653125 (2014)
BindingDB Entry DOI: 10.7270/Q2VQ31BN |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Mus musculus (Mouse)) | BDBM118175
(US8653125, Ia-28)Show SMILES Fc1ccccc1-c1cccc(NC(=O)[C@@H]2CC[C@@H](CC2)NC(=O)c2ccon2)c1 |r,wU:18.22,15.15,(8.52,-2.93,;8.52,-1.39,;9.85,-.62,;9.85,.92,;8.52,1.69,;7.19,.92,;7.19,-.62,;5.85,-1.39,;5.85,-2.93,;4.52,-3.7,;3.19,-2.93,;3.19,-1.39,;1.85,-.62,;.52,-1.39,;.52,-2.93,;-.82,-.62,;-.82,.92,;-2.15,1.69,;-3.48,.92,;-3.48,-.62,;-2.15,-1.39,;-4.82,1.69,;-6.15,.92,;-6.15,-.62,;-7.48,1.69,;-8.95,1.21,;-9.85,2.46,;-8.95,3.7,;-7.48,3.23,;4.52,-.62,)| Show InChI InChI=1S/C23H22FN3O3/c24-20-7-2-1-6-19(20)16-4-3-5-18(14-16)26-22(28)15-8-10-17(11-9-15)25-23(29)21-12-13-30-27-21/h1-7,12-15,17H,8-11H2,(H,25,29)(H,26,28)/t15-,17+ | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 4.10 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Shionogi Co., Ltd.
US Patent
| Assay Description
cDNA sequence encoding mouse NPY Y5 receptor (Biochem. Biophys. Acta 1328: 83-89, 1997) was cloned in the expression vector (pME18S, Takebe et al. Mo... |
US Patent US8653125 (2014)
BindingDB Entry DOI: 10.7270/Q2VQ31BN |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Mus musculus (Mouse)) | BDBM118173
(US8653125, Ia-15)Show SMILES CC(C)n1c2ccc(NC(=O)[C@@H]3CC[C@@H](CC3)NC(=O)c3ccccc3)cc2oc1=O |r,wU:14.17,11.10,(9.4,-4.3,;7.91,-3.9,;6.82,-4.99,;7.51,-2.41,;6.05,-1.94,;4.71,-2.71,;3.38,-1.94,;3.38,-.4,;2.05,.37,;.71,-.4,;.71,-1.94,;-.62,.37,;-.62,1.91,;-1.95,2.68,;-3.29,1.91,;-3.29,.37,;-1.95,-.4,;-4.62,2.68,;-5.96,1.91,;-5.96,.37,;-7.29,2.68,;-8.62,1.91,;-9.96,2.68,;-9.96,4.22,;-8.62,4.99,;-7.29,4.22,;4.71,.37,;6.05,-.4,;7.51,.08,;8.42,-1.17,;9.96,-1.17,)| Show InChI InChI=1S/C24H27N3O4/c1-15(2)27-20-13-12-19(14-21(20)31-24(27)30)26-23(29)17-8-10-18(11-9-17)25-22(28)16-6-4-3-5-7-16/h3-7,12-15,17-18H,8-11H2,1-2H3,(H,25,28)(H,26,29)/t17-,18+ | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | 4.5 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Shionogi Co., Ltd.
US Patent
| Assay Description
cDNA sequence encoding mouse NPY Y5 receptor (Biochem. Biophys. Acta 1328: 83-89, 1997) was cloned in the expression vector (pME18S, Takebe et al. Mo... |
US Patent US8653125 (2014)
BindingDB Entry DOI: 10.7270/Q2VQ31BN |
More data for this
Ligand-Target Pair | |
Search and Browse
