Affinity Data by Patent

Patent code US8685986

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM119438 (BDBM119693 \| US8685986, 12) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.10	-52.0	n/a	n/a	n/a	n/a	n/a	6.0	30
Ube Industries, Ltd. US Patent					Assay Description Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...				US Patent US8685986 (2014) BindingDB Entry DOI: 10.7270/Q28S4NK1
Ube Industries, Ltd. US Patent					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM119442 (US8685986, 17) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.5	-51.2	n/a	n/a	n/a	n/a	n/a	6.0	30
Ube Industries, Ltd. US Patent					Assay Description Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...				US Patent US8685986 (2014) BindingDB Entry DOI: 10.7270/Q28S4NK1
Ube Industries, Ltd. US Patent					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM119432 (US8685986, 3) Show SMILES OC(=O)c1[nH]c(cc1-c1ccc(F)cc1)-c1cccs1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.90	-50.6	n/a	n/a	n/a	n/a	n/a	6.0	30
Ube Industries, Ltd. US Patent					Assay Description Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...				US Patent US8685986 (2014) BindingDB Entry DOI: 10.7270/Q28S4NK1
Ube Industries, Ltd. US Patent					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM119433 (US8685986, 4) Show SMILES OC(=O)c1[nH]c(cc1-c1ccc(O)cc1)-c1ccoc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.80	-49.6	n/a	n/a	n/a	n/a	n/a	6.0	30
Ube Industries, Ltd. US Patent					Assay Description Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...				US Patent US8685986 (2014) BindingDB Entry DOI: 10.7270/Q28S4NK1
Ube Industries, Ltd. US Patent					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM119441 (US8685986, 16) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.10	-49.4	n/a	n/a	n/a	n/a	n/a	6.0	30
Ube Industries, Ltd. US Patent					Assay Description Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...				US Patent US8685986 (2014) BindingDB Entry DOI: 10.7270/Q28S4NK1
Ube Industries, Ltd. US Patent					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM119437 (US8685986, 11) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	3.80	-48.9	n/a	n/a	n/a	n/a	n/a	6.0	30
Ube Industries, Ltd. US Patent					Assay Description Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...				US Patent US8685986 (2014) BindingDB Entry DOI: 10.7270/Q28S4NK1
Ube Industries, Ltd. US Patent					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM119435 (US8685986, 6) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	3.80	-48.9	n/a	n/a	n/a	n/a	n/a	6.0	30
Ube Industries, Ltd. US Patent					Assay Description Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...				US Patent US8685986 (2014) BindingDB Entry DOI: 10.7270/Q28S4NK1
Ube Industries, Ltd. US Patent					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM119436 (US8685986, 9) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4.40	-48.5	n/a	n/a	n/a	n/a	n/a	6.0	30
Ube Industries, Ltd. US Patent					Assay Description Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...				US Patent US8685986 (2014) BindingDB Entry DOI: 10.7270/Q28S4NK1
Ube Industries, Ltd. US Patent					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM119434 (US8685986, 5) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7	-47.3	n/a	n/a	n/a	n/a	n/a	6.0	30
Ube Industries, Ltd. US Patent					Assay Description Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...				US Patent US8685986 (2014) BindingDB Entry DOI: 10.7270/Q28S4NK1
Ube Industries, Ltd. US Patent					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM119443 (US8685986, 18) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	9.20	-46.6	n/a	n/a	n/a	n/a	n/a	6.0	30
Ube Industries, Ltd. US Patent					Assay Description Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...				US Patent US8685986 (2014) BindingDB Entry DOI: 10.7270/Q28S4NK1
Ube Industries, Ltd. US Patent					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM119440 (BDBM119696 \| US8685986, 15) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	US Patent	9.40	-46.6	n/a	n/a	n/a	n/a	n/a	6.0	30
Ube Industries, Ltd. US Patent					Assay Description Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...				US Patent US8685986 (2014) BindingDB Entry DOI: 10.7270/Q28S4NK1
Ube Industries, Ltd. US Patent					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM119439 (BDBM119694 \| US8685986, 13) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	13	-45.8	n/a	n/a	n/a	n/a	n/a	6.0	30
Ube Industries, Ltd. US Patent					Assay Description Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (...				US Patent US8685986 (2014) BindingDB Entry DOI: 10.7270/Q28S4NK1
Ube Industries, Ltd. US Patent					More data for this Ligand-Target Pair

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* indicates data uncertainty>20%