Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kinesin-like protein KIF11 (Homo sapiens (Human)) | BDBM123468 (US8748626, 1) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.840 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Novartis AG US Patent | Assay Description This example provides a representative in vitro assay for determining KSP activity in vitro. Purified microtubules obtained from bovine brain were pu... | US Patent US8748626 (2014) BindingDB Entry DOI: 10.7270/Q2JS9P40 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kinesin-like protein KIF11 (Homo sapiens (Human)) | BDBM123472 (US8748626, 5) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.54 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Novartis AG US Patent | Assay Description This example provides a representative in vitro assay for determining KSP activity in vitro. Purified microtubules obtained from bovine brain were pu... | US Patent US8748626 (2014) BindingDB Entry DOI: 10.7270/Q2JS9P40 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kinesin-like protein KIF11 (Homo sapiens (Human)) | BDBM123470 (US8748626, 3) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Novartis AG US Patent | Assay Description This example provides a representative in vitro assay for determining KSP activity in vitro. Purified microtubules obtained from bovine brain were pu... | US Patent US8748626 (2014) BindingDB Entry DOI: 10.7270/Q2JS9P40 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kinesin-like protein KIF11 (Homo sapiens (Human)) | BDBM123471 (US8748626, 4) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 7.18 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Novartis AG US Patent | Assay Description This example provides a representative in vitro assay for determining KSP activity in vitro. Purified microtubules obtained from bovine brain were pu... | US Patent US8748626 (2014) BindingDB Entry DOI: 10.7270/Q2JS9P40 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kinesin-like protein KIF11 (Homo sapiens (Human)) | BDBM123469 (US8748626, 2) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 10 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Novartis AG US Patent | Assay Description This example provides a representative in vitro assay for determining KSP activity in vitro. Purified microtubules obtained from bovine brain were pu... | US Patent US8748626 (2014) BindingDB Entry DOI: 10.7270/Q2JS9P40 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kinesin-like protein KIF11 (Homo sapiens (Human)) | BDBM123475 (US8748626, 8) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 216 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Novartis AG US Patent | Assay Description This example provides a representative in vitro assay for determining KSP activity in vitro. Purified microtubules obtained from bovine brain were pu... | US Patent US8748626 (2014) BindingDB Entry DOI: 10.7270/Q2JS9P40 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kinesin-like protein KIF11 (Homo sapiens (Human)) | BDBM123474 (US8748626, 7) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 631 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Novartis AG US Patent | Assay Description This example provides a representative in vitro assay for determining KSP activity in vitro. Purified microtubules obtained from bovine brain were pu... | US Patent US8748626 (2014) BindingDB Entry DOI: 10.7270/Q2JS9P40 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kinesin-like protein KIF11 (Homo sapiens (Human)) | BDBM123473 (US8748626, 6) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Novartis AG US Patent | Assay Description This example provides a representative in vitro assay for determining KSP activity in vitro. Purified microtubules obtained from bovine brain were pu... | US Patent US8748626 (2014) BindingDB Entry DOI: 10.7270/Q2JS9P40 | |||||||||||
More data for this Ligand-Target Pair |