Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Genome polyprotein (Hepatitis C virus) | BDBM124107 (US8754105, 23) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.200 | -56.3 | n/a | n/a | n/a | n/a | n/a | 7.5 | 30 |
Medivir AB; Janssen R&D Ireland US Patent | Assay Description The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p... | US Patent US8754105 (2014) BindingDB Entry DOI: 10.7270/Q2QC0250 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM124112 (US8754105, 25) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 2.40 | -50.0 | n/a | n/a | n/a | n/a | n/a | 7.5 | 30 |
Medivir AB; Janssen R&D Ireland US Patent | Assay Description The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p... | US Patent US8754105 (2014) BindingDB Entry DOI: 10.7270/Q2QC0250 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM124111 (US8754105, 24) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 40 | -42.9 | n/a | n/a | n/a | n/a | n/a | 7.5 | 30 |
Medivir AB; Janssen R&D Ireland US Patent | Assay Description The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p... | US Patent US8754105 (2014) BindingDB Entry DOI: 10.7270/Q2QC0250 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM124110 (US8754105, 17) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 43 | -42.8 | n/a | n/a | n/a | n/a | n/a | 7.5 | 30 |
Medivir AB; Janssen R&D Ireland US Patent | Assay Description The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p... | US Patent US8754105 (2014) BindingDB Entry DOI: 10.7270/Q2QC0250 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM124109 (US8754105, 16) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.00E+3 | -34.8 | n/a | n/a | n/a | n/a | n/a | 7.5 | 30 |
Medivir AB; Janssen R&D Ireland US Patent | Assay Description The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p... | US Patent US8754105 (2014) BindingDB Entry DOI: 10.7270/Q2QC0250 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM124108 (US8754105, 22) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 1.07E+3 | -34.6 | n/a | n/a | n/a | n/a | n/a | 7.5 | 30 |
Medivir AB; Janssen R&D Ireland US Patent | Assay Description The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p... | US Patent US8754105 (2014) BindingDB Entry DOI: 10.7270/Q2QC0250 | |||||||||||
More data for this Ligand-Target Pair |