Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serine/threonine-protein kinase ATR (Homo sapiens (Human)) | BDBM132734 (US8846917, I-1) | PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 6 | -46.9 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
Vertex Pharmaceuticals Incorporated US Patent | Assay Description Compounds were screened for their ability to inhibit ATR kinase using a radioactive-phosphate incorporation assay. Assays were carried out in a mixtu... | US Patent US8846917 (2014) BindingDB Entry DOI: 10.7270/Q2CC0ZCB | |||||||||||
More data for this Ligand-Target Pair |