BindingDB logo
myBDB logout

Patent code US8962860

Compile Data Set for Download or QSAR
Found 19 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutaminyl-peptide cyclotransferase


(Homo sapiens (Human))
BDBM149365
PNG
(US8962860, 9)
Show SMILES COc1ccc(cc1O)C1N(C(=O)NC1=O)c1ccc2[nH]cnc2c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
3.24 -49.3 3.08n/an/an/an/an/a30



Probiodrug AG

US Patent


Assay Description
This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...


US Patent US8962860 (2015)


BindingDB Entry DOI: 10.7270/Q2B856V2
More data for this
Ligand-Target Pair
Glutaminyl-peptide cyclotransferase


(Homo sapiens (Human))
BDBM149363
PNG
(US8962860, 6)
Show SMILES CCCOc1ccc(cc1)C1N(C(=O)NC1=O)c1ccc2[nH]cnc2c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
3.80 -48.9 234n/an/an/an/an/a30



Probiodrug AG

US Patent


Assay Description
This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...


US Patent US8962860 (2015)


BindingDB Entry DOI: 10.7270/Q2B856V2
More data for this
Ligand-Target Pair
Glutaminyl-peptide cyclotransferase


(Homo sapiens (Human))
BDBM149366
PNG
(US8962860, 11)
Show SMILES O=C1NC(=O)N(C1c1ccc(cc1)-c1ccccc1)c1ccc2[nH]cnc2c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
4.13 -48.7 48n/an/an/an/an/a30



Probiodrug AG

US Patent


Assay Description
This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...


US Patent US8962860 (2015)


BindingDB Entry DOI: 10.7270/Q2B856V2
More data for this
Ligand-Target Pair
Glutaminyl-peptide cyclotransferase


(Homo sapiens (Human))
BDBM149358
PNG
(US8962860, 1)
Show SMILES O=C1NC(=O)N(C1c1ccc2nsnc2c1)c1ccc2[nH]cnc2c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
6.07 -47.7 69.7n/an/an/an/an/a30



Probiodrug AG

US Patent


Assay Description
This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...


US Patent US8962860 (2015)


BindingDB Entry DOI: 10.7270/Q2B856V2
More data for this
Ligand-Target Pair
Glutaminyl-peptide cyclotransferase


(Homo sapiens (Human))
BDBM149375
PNG
(US8962860, 42)
Show SMILES Fc1cc(Br)ccc1C1N(C(=O)NC1=S)c1ccc2nc[nH]c2c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
6.49 -47.5 24n/an/an/an/an/a30



Probiodrug AG

US Patent


Assay Description
This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...


US Patent US8962860 (2015)


BindingDB Entry DOI: 10.7270/Q2B856V2
More data for this
Ligand-Target Pair
Glutaminyl-peptide cyclotransferase


(Homo sapiens (Human))
BDBM149371
PNG
(US8962860, 16)
Show SMILES O=C1NC(=O)N(C1c1ccc2OCCOc2c1)c1ccc2[nH]cnc2c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
13.6 -45.7 128n/an/an/an/an/a30



Probiodrug AG

US Patent


Assay Description
This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...


US Patent US8962860 (2015)


BindingDB Entry DOI: 10.7270/Q2B856V2
More data for this
Ligand-Target Pair
Glutaminyl-peptide cyclotransferase


(Homo sapiens (Human))
BDBM149376
PNG
(US8962860, 43)
Show SMILES Cc1ccc(C2N(C(=O)NC2=S)c2ccc3[nH]cnc3c2)c(F)c1F
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
17.7 -45.0 326n/an/an/an/an/a30



Probiodrug AG

US Patent


Assay Description
This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...


US Patent US8962860 (2015)


BindingDB Entry DOI: 10.7270/Q2B856V2
More data for this
Ligand-Target Pair
Glutaminyl-peptide cyclotransferase


(Homo sapiens (Human))
BDBM149369
PNG
(US8962860, 14)
Show SMILES Clc1ccccc1C1N(C(=O)NC1=O)c1ccc2[nH]cnc2c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
21.7 -44.5 173n/an/an/an/an/a30



Probiodrug AG

US Patent


Assay Description
This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...


US Patent US8962860 (2015)


BindingDB Entry DOI: 10.7270/Q2B856V2
More data for this
Ligand-Target Pair
Glutaminyl-peptide cyclotransferase


(Homo sapiens (Human))
BDBM149362
PNG
(US8962860, 5)
Show SMILES Fc1ccc(Br)c(c1)C1N(C(=O)NC1=O)c1ccc2[nH]cnc2c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
34.8 -43.3 182n/an/an/an/an/a30



Probiodrug AG

US Patent


Assay Description
This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...


US Patent US8962860 (2015)


BindingDB Entry DOI: 10.7270/Q2B856V2
More data for this
Ligand-Target Pair
Glutaminyl-peptide cyclotransferase


(Homo sapiens (Human))
BDBM149367
PNG
(US8962860, 12)
Show SMILES Clc1cccc(c1)C1N(C(=O)NC1=O)c1ccc2[nH]cnc2c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
36 -43.2 523n/an/an/an/an/a30



Probiodrug AG

US Patent


Assay Description
This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...


US Patent US8962860 (2015)


BindingDB Entry DOI: 10.7270/Q2B856V2
More data for this
Ligand-Target Pair
Glutaminyl-peptide cyclotransferase


(Homo sapiens (Human))
BDBM149359
PNG
(US8962860, 2)
Show SMILES O=C1NC(=O)N(C1c1ccccc1)c1ccc2[nH]cnc2c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
41.3 -42.9 741n/an/an/an/an/a30



Probiodrug AG

US Patent


Assay Description
This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...


US Patent US8962860 (2015)


BindingDB Entry DOI: 10.7270/Q2B856V2
More data for this
Ligand-Target Pair
Glutaminyl-peptide cyclotransferase


(Homo sapiens (Human))
BDBM149368
PNG
(US8962860, 13)
Show SMILES Clc1ccc(cc1)C1N(C(=O)NC1=O)c1ccc2[nH]cnc2c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
42.8 -42.8 298n/an/an/an/an/a30



Probiodrug AG

US Patent


Assay Description
This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...


US Patent US8962860 (2015)


BindingDB Entry DOI: 10.7270/Q2B856V2
More data for this
Ligand-Target Pair
Glutaminyl-peptide cyclotransferase


(Homo sapiens (Human))
BDBM149373
PNG
(US8962860, 40)
Show SMILES Clc1ccc(cc1)C1N(C(=O)NC1=S)c1ccc2[nH]cnc2c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
45.9 -42.6 256n/an/an/an/an/a30



Probiodrug AG

US Patent


Assay Description
This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...


US Patent US8962860 (2015)


BindingDB Entry DOI: 10.7270/Q2B856V2
More data for this
Ligand-Target Pair
Glutaminyl-peptide cyclotransferase


(Homo sapiens (Human))
BDBM149360
PNG
(US8962860, 3)
Show SMILES Cc1ccc(O)c(c1)C1N(C(=O)NC1=O)c1ccc2[nH]cnc2c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
48 -42.5 34.9n/an/an/an/an/a30



Probiodrug AG

US Patent


Assay Description
This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...


US Patent US8962860 (2015)


BindingDB Entry DOI: 10.7270/Q2B856V2
More data for this
Ligand-Target Pair
Glutaminyl-peptide cyclotransferase


(Homo sapiens (Human))
BDBM149361
PNG
(US8962860, 4)
Show SMILES Fc1ccc(cc1C1N(C(=O)NC1=O)c1ccc2[nH]cnc2c1)C(F)(F)F
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
51.6 -42.3 560n/an/an/an/an/a30



Probiodrug AG

US Patent


Assay Description
This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...


US Patent US8962860 (2015)


BindingDB Entry DOI: 10.7270/Q2B856V2
More data for this
Ligand-Target Pair
Glutaminyl-peptide cyclotransferase


(Homo sapiens (Human))
BDBM149370
PNG
(US8962860, 15)
Show SMILES Fc1ccc(cc1)C1N(C(=O)NC1=O)c1ccc2[nH]cnc2c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
58.5 -42.0 540n/an/an/an/an/a30



Probiodrug AG

US Patent


Assay Description
This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...


US Patent US8962860 (2015)


BindingDB Entry DOI: 10.7270/Q2B856V2
More data for this
Ligand-Target Pair
Glutaminyl-peptide cyclotransferase


(Homo sapiens (Human))
BDBM149364
PNG
(US8962860, 7)
Show SMILES FC(F)(F)c1cc(ccc1Cl)C1N(C(=O)NC1=O)c1ccc2[nH]cnc2c1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
65.5 -41.7 430n/an/an/an/an/a30



Probiodrug AG

US Patent


Assay Description
This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...


US Patent US8962860 (2015)


BindingDB Entry DOI: 10.7270/Q2B856V2
More data for this
Ligand-Target Pair
Glutaminyl-peptide cyclotransferase


(Homo sapiens (Human))
BDBM149374
PNG
(US8962860, 41)
Show SMILES Fc1ccc(C2N(C(=O)NC2=S)c2ccc3nc[nH]c3c2)c(F)c1F
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
85.3 -41.0 485n/an/an/an/an/a30



Probiodrug AG

US Patent


Assay Description
This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...


US Patent US8962860 (2015)


BindingDB Entry DOI: 10.7270/Q2B856V2
More data for this
Ligand-Target Pair
Glutaminyl-peptide cyclotransferase


(Homo sapiens (Human))
BDBM149372
PNG
(US8962860, 32)
Show SMILES O=C1NC(=O)C2(Cc3ccccc3C2)N1c1ccc2[nH]cnc2c1
Show InChI InChI=1S/C18H14N4O2/c23-16-18(8-11-3-1-2-4-12(11)9-18)22(17(24)21-16)13-5-6-14-15(7-13)20-10-19-14/h1-7,10H,8-9H2,(H,19,20)(H,21,23,24)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
159 -39.5 821n/an/an/an/an/a30



Probiodrug AG

US Patent


Assay Description
This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...


US Patent US8962860 (2015)


BindingDB Entry DOI: 10.7270/Q2B856V2
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%