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Patent code US8980932

Compile Data Set for Download or QSAR
Found 40 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM150251
PNG
(US8980932, 6c (DH310))
Show SMILES Cc1ncc(n1CCNC(=S)NCCc1ccc(cc1)S(N)(=O)=O)[N+]([O-])=O
Show InChI InChI=1S/C15H20N6O4S2/c1-11-19-10-14(21(22)23)20(11)9-8-18-15(26)17-7-6-12-2-4-13(5-3-12)27(16,24)25/h2-5,10H,6-9H2,1H3,(H2,16,24,25)(H2,17,18,26)
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US Patent
2.90n/an/an/an/an/an/a7.5n/a



Stichting Maastricht Radiation Oncology “Maastro-Clinic”; Université Montpellier 2 Sciences et Techniques

US Patent


Assay Description
The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...


US Patent US8980932 (2015)


BindingDB Entry DOI: 10.7270/Q2GX499J
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM150254
PNG
(US8980932, 4d (DH302))
Show SMILES NS(=O)(=O)c1cccc(NC(=O)Cn2ccnc2[N+]([O-])=O)c1
Show InChI InChI=1S/C11H11N5O5S/c12-22(20,21)9-3-1-2-8(6-9)14-10(17)7-15-5-4-13-11(15)16(18)19/h1-6H,7H2,(H,14,17)(H2,12,20,21)
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3.80n/an/an/an/an/an/a7.5n/a



Stichting Maastricht Radiation Oncology “Maastro-Clinic”; Université Montpellier 2 Sciences et Techniques

US Patent


Assay Description
The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...


US Patent US8980932 (2015)


BindingDB Entry DOI: 10.7270/Q2GX499J
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM150256
PNG
(US8980932, 4c (DH305))
Show SMILES NS(=O)(=O)c1ccc(CCNC(=O)Cn2ccnc2[N+]([O-])=O)cc1
Show InChI InChI=1S/C13H15N5O5S/c14-24(22,23)11-3-1-10(2-4-11)5-6-15-12(19)9-17-8-7-16-13(17)18(20)21/h1-4,7-8H,5-6,9H2,(H,15,19)(H2,14,22,23)
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4.80n/an/an/an/an/an/a7.5n/a



Stichting Maastricht Radiation Oncology “Maastro-Clinic”; Université Montpellier 2 Sciences et Techniques

US Patent


Assay Description
The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...


US Patent US8980932 (2015)


BindingDB Entry DOI: 10.7270/Q2GX499J
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM150249
PNG
(US8980932, 6a (DH307))
Show SMILES Cc1ncc(n1CCNC(=S)Nc1ccc(cc1)S(N)(=O)=O)[N+]([O-])=O
Show InChI InChI=1S/C13H16N6O4S2/c1-9-16-8-12(19(20)21)18(9)7-6-15-13(24)17-10-2-4-11(5-3-10)25(14,22)23/h2-5,8H,6-7H2,1H3,(H2,14,22,23)(H2,15,17,24)
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5.5n/an/an/an/an/an/a7.5n/a



Stichting Maastricht Radiation Oncology “Maastro-Clinic”; Université Montpellier 2 Sciences et Techniques

US Patent


Assay Description
The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...


US Patent US8980932 (2015)


BindingDB Entry DOI: 10.7270/Q2GX499J
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM150252
PNG
(US8980932, 6d (DH308))
Show SMILES Cc1ncc(n1CCNC(=S)Nc1cccc(c1)S(N)(=O)=O)[N+]([O-])=O
Show InChI InChI=1S/C13H16N6O4S2/c1-9-16-8-12(19(20)21)18(9)6-5-15-13(24)17-10-3-2-4-11(7-10)25(14,22)23/h2-4,7-8H,5-6H2,1H3,(H2,14,22,23)(H2,15,17,24)
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6.60n/an/an/an/an/an/a7.5n/a



Stichting Maastricht Radiation Oncology “Maastro-Clinic”; Université Montpellier 2 Sciences et Techniques

US Patent


Assay Description
The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...


US Patent US8980932 (2015)


BindingDB Entry DOI: 10.7270/Q2GX499J
More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM150256
PNG
(US8980932, 4c (DH305))
Show SMILES NS(=O)(=O)c1ccc(CCNC(=O)Cn2ccnc2[N+]([O-])=O)cc1
Show InChI InChI=1S/C13H15N5O5S/c14-24(22,23)11-3-1-10(2-4-11)5-6-15-12(19)9-17-8-7-16-13(17)18(20)21/h1-4,7-8H,5-6,9H2,(H,15,19)(H2,14,22,23)
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6.70n/an/an/an/an/an/a7.5n/a



Stichting Maastricht Radiation Oncology “Maastro-Clinic”; Université Montpellier 2 Sciences et Techniques

US Patent


Assay Description
The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...


US Patent US8980932 (2015)


BindingDB Entry DOI: 10.7270/Q2GX499J
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM150250
PNG
(US8980932, 6b (DH309))
Show SMILES Cc1ncc(n1CCNC(=S)NCc1ccc(cc1)S(N)(=O)=O)[N+]([O-])=O
Show InChI InChI=1S/C14H18N6O4S2/c1-10-17-9-13(20(21)22)19(10)7-6-16-14(25)18-8-11-2-4-12(5-3-11)26(15,23)24/h2-5,9H,6-8H2,1H3,(H2,15,23,24)(H2,16,18,25)
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7.20n/an/an/an/an/an/a7.5n/a



Stichting Maastricht Radiation Oncology “Maastro-Clinic”; Université Montpellier 2 Sciences et Techniques

US Patent


Assay Description
The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...


US Patent US8980932 (2015)


BindingDB Entry DOI: 10.7270/Q2GX499J
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM150249
PNG
(US8980932, 6a (DH307))
Show SMILES Cc1ncc(n1CCNC(=S)Nc1ccc(cc1)S(N)(=O)=O)[N+]([O-])=O
Show InChI InChI=1S/C13H16N6O4S2/c1-9-16-8-12(19(20)21)18(9)7-6-15-13(24)17-10-2-4-11(5-3-10)25(14,22)23/h2-5,8H,6-7H2,1H3,(H2,14,22,23)(H2,15,17,24)
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7.30n/an/an/an/an/an/a7.5n/a



Stichting Maastricht Radiation Oncology “Maastro-Clinic”; Université Montpellier 2 Sciences et Techniques

US Patent


Assay Description
The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...


US Patent US8980932 (2015)


BindingDB Entry DOI: 10.7270/Q2GX499J
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM150254
PNG
(US8980932, 4d (DH302))
Show SMILES NS(=O)(=O)c1cccc(NC(=O)Cn2ccnc2[N+]([O-])=O)c1
Show InChI InChI=1S/C11H11N5O5S/c12-22(20,21)9-3-1-2-8(6-9)14-10(17)7-15-5-4-13-11(15)16(18)19/h1-6H,7H2,(H,14,17)(H2,12,20,21)
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7.30n/an/an/an/an/an/a7.5n/a



Stichting Maastricht Radiation Oncology “Maastro-Clinic”; Université Montpellier 2 Sciences et Techniques

US Patent


Assay Description
The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...


US Patent US8980932 (2015)


BindingDB Entry DOI: 10.7270/Q2GX499J
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM150250
PNG
(US8980932, 6b (DH309))
Show SMILES Cc1ncc(n1CCNC(=S)NCc1ccc(cc1)S(N)(=O)=O)[N+]([O-])=O
Show InChI InChI=1S/C14H18N6O4S2/c1-10-17-9-13(20(21)22)19(10)7-6-16-14(25)18-8-11-2-4-12(5-3-11)26(15,23)24/h2-5,9H,6-8H2,1H3,(H2,15,23,24)(H2,16,18,25)
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7.40n/an/an/an/an/an/a7.5n/a



Stichting Maastricht Radiation Oncology “Maastro-Clinic”; Université Montpellier 2 Sciences et Techniques

US Patent


Assay Description
The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...


US Patent US8980932 (2015)


BindingDB Entry DOI: 10.7270/Q2GX499J
More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM150252
PNG
(US8980932, 6d (DH308))
Show SMILES Cc1ncc(n1CCNC(=S)Nc1cccc(c1)S(N)(=O)=O)[N+]([O-])=O
Show InChI InChI=1S/C13H16N6O4S2/c1-9-16-8-12(19(20)21)18(9)6-5-15-13(24)17-10-3-2-4-11(7-10)25(14,22)23/h2-4,7-8H,5-6H2,1H3,(H2,14,22,23)(H2,15,17,24)
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7.60n/an/an/an/an/an/a7.5n/a



Stichting Maastricht Radiation Oncology “Maastro-Clinic”; Université Montpellier 2 Sciences et Techniques

US Patent


Assay Description
The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...


US Patent US8980932 (2015)


BindingDB Entry DOI: 10.7270/Q2GX499J
More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM150250
PNG
(US8980932, 6b (DH309))
Show SMILES Cc1ncc(n1CCNC(=S)NCc1ccc(cc1)S(N)(=O)=O)[N+]([O-])=O
Show InChI InChI=1S/C14H18N6O4S2/c1-10-17-9-13(20(21)22)19(10)7-6-16-14(25)18-8-11-2-4-12(5-3-11)26(15,23)24/h2-5,9H,6-8H2,1H3,(H2,15,23,24)(H2,16,18,25)
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US Patent
7.70n/an/an/an/an/an/a7.5n/a



Stichting Maastricht Radiation Oncology “Maastro-Clinic”; Université Montpellier 2 Sciences et Techniques

US Patent


Assay Description
The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...


US Patent US8980932 (2015)


BindingDB Entry DOI: 10.7270/Q2GX499J
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM150252
PNG
(US8980932, 6d (DH308))
Show SMILES Cc1ncc(n1CCNC(=S)Nc1cccc(c1)S(N)(=O)=O)[N+]([O-])=O
Show InChI InChI=1S/C13H16N6O4S2/c1-9-16-8-12(19(20)21)18(9)6-5-15-13(24)17-10-3-2-4-11(7-10)25(14,22)23/h2-4,7-8H,5-6H2,1H3,(H2,14,22,23)(H2,15,17,24)
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7.80n/an/an/an/an/an/a7.5n/a



Stichting Maastricht Radiation Oncology “Maastro-Clinic”; Université Montpellier 2 Sciences et Techniques

US Patent


Assay Description
The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...


US Patent US8980932 (2015)


BindingDB Entry DOI: 10.7270/Q2GX499J
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM150255
PNG
(US8980932, 4b (DH304))
Show SMILES NS(=O)(=O)c1ccc(CNC(=O)Cn2ccnc2[N+]([O-])=O)cc1
Show InChI InChI=1S/C12H13N5O5S/c13-23(21,22)10-3-1-9(2-4-10)7-15-11(18)8-16-6-5-14-12(16)17(19)20/h1-6H,7-8H2,(H,15,18)(H2,13,21,22)
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7.90n/an/an/an/an/an/a7.5n/a



Stichting Maastricht Radiation Oncology “Maastro-Clinic”; Université Montpellier 2 Sciences et Techniques

US Patent


Assay Description
The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...


US Patent US8980932 (2015)


BindingDB Entry DOI: 10.7270/Q2GX499J
More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM150254
PNG
(US8980932, 4d (DH302))
Show SMILES NS(=O)(=O)c1cccc(NC(=O)Cn2ccnc2[N+]([O-])=O)c1
Show InChI InChI=1S/C11H11N5O5S/c12-22(20,21)9-3-1-2-8(6-9)14-10(17)7-15-5-4-13-11(15)16(18)19/h1-6H,7H2,(H,14,17)(H2,12,20,21)
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8n/an/an/an/an/an/a7.5n/a



Stichting Maastricht Radiation Oncology “Maastro-Clinic”; Université Montpellier 2 Sciences et Techniques

US Patent


Assay Description
The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...


US Patent US8980932 (2015)


BindingDB Entry DOI: 10.7270/Q2GX499J
More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM150249
PNG
(US8980932, 6a (DH307))
Show SMILES Cc1ncc(n1CCNC(=S)Nc1ccc(cc1)S(N)(=O)=O)[N+]([O-])=O
Show InChI InChI=1S/C13H16N6O4S2/c1-9-16-8-12(19(20)21)18(9)7-6-15-13(24)17-10-2-4-11(5-3-10)25(14,22)23/h2-5,8H,6-7H2,1H3,(H2,14,22,23)(H2,15,17,24)
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8n/an/an/an/an/an/a7.5n/a



Stichting Maastricht Radiation Oncology “Maastro-Clinic”; Université Montpellier 2 Sciences et Techniques

US Patent


Assay Description
The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...


US Patent US8980932 (2015)


BindingDB Entry DOI: 10.7270/Q2GX499J
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM150256
PNG
(US8980932, 4c (DH305))
Show SMILES NS(=O)(=O)c1ccc(CCNC(=O)Cn2ccnc2[N+]([O-])=O)cc1
Show InChI InChI=1S/C13H15N5O5S/c14-24(22,23)11-3-1-10(2-4-11)5-6-15-12(19)9-17-8-7-16-13(17)18(20)21/h1-4,7-8H,5-6,9H2,(H,15,19)(H2,14,22,23)
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8n/an/an/an/an/an/a7.5n/a



Stichting Maastricht Radiation Oncology “Maastro-Clinic”; Université Montpellier 2 Sciences et Techniques

US Patent


Assay Description
The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...


US Patent US8980932 (2015)


BindingDB Entry DOI: 10.7270/Q2GX499J
More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM150255
PNG
(US8980932, 4b (DH304))
Show SMILES NS(=O)(=O)c1ccc(CNC(=O)Cn2ccnc2[N+]([O-])=O)cc1
Show InChI InChI=1S/C12H13N5O5S/c13-23(21,22)10-3-1-9(2-4-10)7-15-11(18)8-16-6-5-14-12(16)17(19)20/h1-6H,7-8H2,(H,15,18)(H2,13,21,22)
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8.10n/an/an/an/an/an/a7.5n/a



Stichting Maastricht Radiation Oncology “Maastro-Clinic”; Université Montpellier 2 Sciences et Techniques

US Patent


Assay Description
The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...


US Patent US8980932 (2015)


BindingDB Entry DOI: 10.7270/Q2GX499J
More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM150248
PNG
(US8980932, 7 (DH348))
Show SMILES Cc1ncc(n1CCNS(=O)(=O)ON)[N+]([O-])=O
Show InChI InChI=1S/C6H11N5O5S/c1-5-8-4-6(11(12)13)10(5)3-2-9-17(14,15)16-7/h4,9H,2-3,7H2,1H3
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8.10n/an/an/an/an/an/a7.5n/a



Stichting Maastricht Radiation Oncology “Maastro-Clinic”; Université Montpellier 2 Sciences et Techniques

US Patent


Assay Description
The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...


US Patent US8980932 (2015)


BindingDB Entry DOI: 10.7270/Q2GX499J
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM150247
PNG
(US8980932, 9 (DH338))
Show SMILES Cc1ncc(n1CCOS(=O)(=O)ON)[N+]([O-])=O
Show InChI InChI=1S/C6H10N4O6S/c1-5-8-4-6(10(11)12)9(5)2-3-15-17(13,14)16-7/h4H,2-3,7H2,1H3
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US Patent
8.30n/an/an/an/an/an/a7.5n/a



Stichting Maastricht Radiation Oncology “Maastro-Clinic”; Université Montpellier 2 Sciences et Techniques

US Patent


Assay Description
The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...


US Patent US8980932 (2015)


BindingDB Entry DOI: 10.7270/Q2GX499J
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM150251
PNG
(US8980932, 6c (DH310))
Show SMILES Cc1ncc(n1CCNC(=S)NCCc1ccc(cc1)S(N)(=O)=O)[N+]([O-])=O
Show InChI InChI=1S/C15H20N6O4S2/c1-11-19-10-14(21(22)23)20(11)9-8-18-15(26)17-7-6-12-2-4-13(5-3-12)27(16,24)25/h2-5,10H,6-9H2,1H3,(H2,16,24,25)(H2,17,18,26)
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8.30n/an/an/an/an/an/a7.5n/a



Stichting Maastricht Radiation Oncology “Maastro-Clinic”; Université Montpellier 2 Sciences et Techniques

US Patent


Assay Description
The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...


US Patent US8980932 (2015)


BindingDB Entry DOI: 10.7270/Q2GX499J
More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM150251
PNG
(US8980932, 6c (DH310))
Show SMILES Cc1ncc(n1CCNC(=S)NCCc1ccc(cc1)S(N)(=O)=O)[N+]([O-])=O
Show InChI InChI=1S/C15H20N6O4S2/c1-11-19-10-14(21(22)23)20(11)9-8-18-15(26)17-7-6-12-2-4-13(5-3-12)27(16,24)25/h2-5,10H,6-9H2,1H3,(H2,16,24,25)(H2,17,18,26)
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8.5n/an/an/an/an/an/a7.5n/a



Stichting Maastricht Radiation Oncology “Maastro-Clinic”; Université Montpellier 2 Sciences et Techniques

US Patent


Assay Description
The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...


US Patent US8980932 (2015)


BindingDB Entry DOI: 10.7270/Q2GX499J
More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM150247
PNG
(US8980932, 9 (DH338))
Show SMILES Cc1ncc(n1CCOS(=O)(=O)ON)[N+]([O-])=O
Show InChI InChI=1S/C6H10N4O6S/c1-5-8-4-6(10(11)12)9(5)2-3-15-17(13,14)16-7/h4H,2-3,7H2,1H3
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8.90n/an/an/an/an/an/a7.5n/a



Stichting Maastricht Radiation Oncology “Maastro-Clinic”; Université Montpellier 2 Sciences et Techniques

US Patent


Assay Description
The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...


US Patent US8980932 (2015)


BindingDB Entry DOI: 10.7270/Q2GX499J
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM150248
PNG
(US8980932, 7 (DH348))
Show SMILES Cc1ncc(n1CCNS(=O)(=O)ON)[N+]([O-])=O
Show InChI InChI=1S/C6H11N5O5S/c1-5-8-4-6(11(12)13)10(5)3-2-9-17(14,15)16-7/h4,9H,2-3,7H2,1H3
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10.1n/an/an/an/an/an/a7.5n/a



Stichting Maastricht Radiation Oncology “Maastro-Clinic”; Université Montpellier 2 Sciences et Techniques

US Patent


Assay Description
The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...


US Patent US8980932 (2015)


BindingDB Entry DOI: 10.7270/Q2GX499J
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM150248
PNG
(US8980932, 7 (DH348))
Show SMILES Cc1ncc(n1CCNS(=O)(=O)ON)[N+]([O-])=O
Show InChI InChI=1S/C6H11N5O5S/c1-5-8-4-6(11(12)13)10(5)3-2-9-17(14,15)16-7/h4,9H,2-3,7H2,1H3
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20.4n/an/an/an/an/an/a7.5n/a



Stichting Maastricht Radiation Oncology “Maastro-Clinic”; Université Montpellier 2 Sciences et Techniques

US Patent


Assay Description
The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...


US Patent US8980932 (2015)


BindingDB Entry DOI: 10.7270/Q2GX499J
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM150247
PNG
(US8980932, 9 (DH338))
Show SMILES Cc1ncc(n1CCOS(=O)(=O)ON)[N+]([O-])=O
Show InChI InChI=1S/C6H10N4O6S/c1-5-8-4-6(10(11)12)9(5)2-3-15-17(13,14)16-7/h4H,2-3,7H2,1H3
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33.8n/an/an/an/an/an/a7.5n/a



Stichting Maastricht Radiation Oncology “Maastro-Clinic”; Université Montpellier 2 Sciences et Techniques

US Patent


Assay Description
The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...


US Patent US8980932 (2015)


BindingDB Entry DOI: 10.7270/Q2GX499J
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM150255
PNG
(US8980932, 4b (DH304))
Show SMILES NS(=O)(=O)c1ccc(CNC(=O)Cn2ccnc2[N+]([O-])=O)cc1
Show InChI InChI=1S/C12H13N5O5S/c13-23(21,22)10-3-1-9(2-4-10)7-15-11(18)8-16-6-5-14-12(16)17(19)20/h1-6H,7-8H2,(H,15,18)(H2,13,21,22)
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37n/an/an/an/an/an/a7.5n/a



Stichting Maastricht Radiation Oncology “Maastro-Clinic”; Université Montpellier 2 Sciences et Techniques

US Patent


Assay Description
The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...


US Patent US8980932 (2015)


BindingDB Entry DOI: 10.7270/Q2GX499J
More data for this
Ligand-Target Pair
Carbonic anhydrase 12


(Homo sapiens (Human))
BDBM150253
PNG
(US8980932, 4a (DH296))
Show SMILES NS(=O)(=O)c1ccc(NC(=O)Cn2ccnc2[N+]([O-])=O)cc1
Show InChI InChI=1S/C11H11N5O5S/c12-22(20,21)9-3-1-8(2-4-9)14-10(17)7-15-6-5-13-11(15)16(18)19/h1-6H,7H2,(H,14,17)(H2,12,20,21)
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64n/an/an/an/an/an/a7.5n/a



Stichting Maastricht Radiation Oncology “Maastro-Clinic”; Université Montpellier 2 Sciences et Techniques

US Patent


Assay Description
The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...


US Patent US8980932 (2015)


BindingDB Entry DOI: 10.7270/Q2GX499J
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM150253
PNG
(US8980932, 4a (DH296))
Show SMILES NS(=O)(=O)c1ccc(NC(=O)Cn2ccnc2[N+]([O-])=O)cc1
Show InChI InChI=1S/C11H11N5O5S/c12-22(20,21)9-3-1-8(2-4-9)14-10(17)7-15-6-5-13-11(15)16(18)19/h1-6H,7H2,(H,14,17)(H2,12,20,21)
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70n/an/an/an/an/an/a7.5n/a



Stichting Maastricht Radiation Oncology “Maastro-Clinic”; Université Montpellier 2 Sciences et Techniques

US Patent


Assay Description
The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...


US Patent US8980932 (2015)


BindingDB Entry DOI: 10.7270/Q2GX499J
More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM150251
PNG
(US8980932, 6c (DH310))
Show SMILES Cc1ncc(n1CCNC(=S)NCCc1ccc(cc1)S(N)(=O)=O)[N+]([O-])=O
Show InChI InChI=1S/C15H20N6O4S2/c1-11-19-10-14(21(22)23)20(11)9-8-18-15(26)17-7-6-12-2-4-13(5-3-12)27(16,24)25/h2-5,10H,6-9H2,1H3,(H2,16,24,25)(H2,17,18,26)
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79n/an/an/an/an/an/a7.5n/a



Stichting Maastricht Radiation Oncology “Maastro-Clinic”; Université Montpellier 2 Sciences et Techniques

US Patent


Assay Description
The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...


US Patent US8980932 (2015)


BindingDB Entry DOI: 10.7270/Q2GX499J
More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM150256
PNG
(US8980932, 4c (DH305))
Show SMILES NS(=O)(=O)c1ccc(CCNC(=O)Cn2ccnc2[N+]([O-])=O)cc1
Show InChI InChI=1S/C13H15N5O5S/c14-24(22,23)11-3-1-10(2-4-11)5-6-15-12(19)9-17-8-7-16-13(17)18(20)21/h1-4,7-8H,5-6,9H2,(H,15,19)(H2,14,22,23)
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79n/an/an/an/an/an/a7.5n/a



Stichting Maastricht Radiation Oncology “Maastro-Clinic”; Université Montpellier 2 Sciences et Techniques

US Patent


Assay Description
The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...


US Patent US8980932 (2015)


BindingDB Entry DOI: 10.7270/Q2GX499J
More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM150252
PNG
(US8980932, 6d (DH308))
Show SMILES Cc1ncc(n1CCNC(=S)Nc1cccc(c1)S(N)(=O)=O)[N+]([O-])=O
Show InChI InChI=1S/C13H16N6O4S2/c1-9-16-8-12(19(20)21)18(9)6-5-15-13(24)17-10-3-2-4-11(7-10)25(14,22)23/h2-4,7-8H,5-6H2,1H3,(H2,14,22,23)(H2,15,17,24)
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84n/an/an/an/an/an/a7.5n/a



Stichting Maastricht Radiation Oncology “Maastro-Clinic”; Université Montpellier 2 Sciences et Techniques

US Patent


Assay Description
The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...


US Patent US8980932 (2015)


BindingDB Entry DOI: 10.7270/Q2GX499J
More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM150254
PNG
(US8980932, 4d (DH302))
Show SMILES NS(=O)(=O)c1cccc(NC(=O)Cn2ccnc2[N+]([O-])=O)c1
Show InChI InChI=1S/C11H11N5O5S/c12-22(20,21)9-3-1-2-8(6-9)14-10(17)7-15-5-4-13-11(15)16(18)19/h1-6H,7H2,(H,14,17)(H2,12,20,21)
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101n/an/an/an/an/an/a7.5n/a



Stichting Maastricht Radiation Oncology “Maastro-Clinic”; Université Montpellier 2 Sciences et Techniques

US Patent


Assay Description
The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...


US Patent US8980932 (2015)


BindingDB Entry DOI: 10.7270/Q2GX499J
More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM150249
PNG
(US8980932, 6a (DH307))
Show SMILES Cc1ncc(n1CCNC(=S)Nc1ccc(cc1)S(N)(=O)=O)[N+]([O-])=O
Show InChI InChI=1S/C13H16N6O4S2/c1-9-16-8-12(19(20)21)18(9)7-6-15-13(24)17-10-2-4-11(5-3-10)25(14,22)23/h2-5,8H,6-7H2,1H3,(H2,14,22,23)(H2,15,17,24)
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105n/an/an/an/an/an/a7.5n/a



Stichting Maastricht Radiation Oncology “Maastro-Clinic”; Université Montpellier 2 Sciences et Techniques

US Patent


Assay Description
The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...


US Patent US8980932 (2015)


BindingDB Entry DOI: 10.7270/Q2GX499J
More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM150255
PNG
(US8980932, 4b (DH304))
Show SMILES NS(=O)(=O)c1ccc(CNC(=O)Cn2ccnc2[N+]([O-])=O)cc1
Show InChI InChI=1S/C12H13N5O5S/c13-23(21,22)10-3-1-9(2-4-10)7-15-11(18)8-16-6-5-14-12(16)17(19)20/h1-6H,7-8H2,(H,15,18)(H2,13,21,22)
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107n/an/an/an/an/an/a7.5n/a



Stichting Maastricht Radiation Oncology “Maastro-Clinic”; Université Montpellier 2 Sciences et Techniques

US Patent


Assay Description
The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...


US Patent US8980932 (2015)


BindingDB Entry DOI: 10.7270/Q2GX499J
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM150253
PNG
(US8980932, 4a (DH296))
Show SMILES NS(=O)(=O)c1ccc(NC(=O)Cn2ccnc2[N+]([O-])=O)cc1
Show InChI InChI=1S/C11H11N5O5S/c12-22(20,21)9-3-1-8(2-4-9)14-10(17)7-15-6-5-13-11(15)16(18)19/h1-6H,7H2,(H,14,17)(H2,12,20,21)
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330n/an/an/an/an/an/a7.5n/a



Stichting Maastricht Radiation Oncology “Maastro-Clinic”; Université Montpellier 2 Sciences et Techniques

US Patent


Assay Description
The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...


US Patent US8980932 (2015)


BindingDB Entry DOI: 10.7270/Q2GX499J
More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM150250
PNG
(US8980932, 6b (DH309))
Show SMILES Cc1ncc(n1CCNC(=S)NCc1ccc(cc1)S(N)(=O)=O)[N+]([O-])=O
Show InChI InChI=1S/C14H18N6O4S2/c1-10-17-9-13(20(21)22)19(10)7-6-16-14(25)18-8-11-2-4-12(5-3-11)26(15,23)24/h2-5,9H,6-8H2,1H3,(H2,15,23,24)(H2,16,18,25)
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483n/an/an/an/an/an/a7.5n/a



Stichting Maastricht Radiation Oncology “Maastro-Clinic”; Université Montpellier 2 Sciences et Techniques

US Patent


Assay Description
The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...


US Patent US8980932 (2015)


BindingDB Entry DOI: 10.7270/Q2GX499J
More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM150253
PNG
(US8980932, 4a (DH296))
Show SMILES NS(=O)(=O)c1ccc(NC(=O)Cn2ccnc2[N+]([O-])=O)cc1
Show InChI InChI=1S/C11H11N5O5S/c12-22(20,21)9-3-1-8(2-4-9)14-10(17)7-15-6-5-13-11(15)16(18)19/h1-6H,7H2,(H,14,17)(H2,12,20,21)
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3.20E+3n/an/an/an/an/an/a7.5n/a



Stichting Maastricht Radiation Oncology “Maastro-Clinic”; Université Montpellier 2 Sciences et Techniques

US Patent


Assay Description
The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...


US Patent US8980932 (2015)


BindingDB Entry DOI: 10.7270/Q2GX499J
More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM150247
PNG
(US8980932, 9 (DH338))
Show SMILES Cc1ncc(n1CCOS(=O)(=O)ON)[N+]([O-])=O
Show InChI InChI=1S/C6H10N4O6S/c1-5-8-4-6(10(11)12)9(5)2-3-15-17(13,14)16-7/h4H,2-3,7H2,1H3
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UniChem
US Patent
4.44E+3n/an/an/an/an/an/a7.5n/a



Stichting Maastricht Radiation Oncology “Maastro-Clinic”; Université Montpellier 2 Sciences et Techniques

US Patent


Assay Description
The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...


US Patent US8980932 (2015)


BindingDB Entry DOI: 10.7270/Q2GX499J
More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM150248
PNG
(US8980932, 7 (DH348))
Show SMILES Cc1ncc(n1CCNS(=O)(=O)ON)[N+]([O-])=O
Show InChI InChI=1S/C6H11N5O5S/c1-5-8-4-6(11(12)13)10(5)3-2-9-17(14,15)16-7/h4,9H,2-3,7H2,1H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
9.58E+3n/an/an/an/an/an/a7.5n/a



Stichting Maastricht Radiation Oncology “Maastro-Clinic”; Université Montpellier 2 Sciences et Techniques

US Patent


Assay Description
The inhibition constants (K) the compounds for four CA isozymes, CA I, II, IX and XII were determined. An Applied Photophysics (Oxford, UK) stopped-f...


US Patent US8980932 (2015)


BindingDB Entry DOI: 10.7270/Q2GX499J
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%