Affinity Data by Patent

Patent code US8993568

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM152809 (US8993568, 5) Show SMILES Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	4
Eli Lilly and Company US Patent					Assay Description The in vitro inhibitory activity of compounds against human MOGAT-2 is evaluated in this assay. MOGAT-2 transfers an oleoyl group to monooleoyl-glyce...				US Patent US8993568 (2015) BindingDB Entry DOI: 10.7270/Q2WM1C4M
Eli Lilly and Company US Patent					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM152811 (US8993568, 14) Show SMILES Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	4
Eli Lilly and Company US Patent					Assay Description The in vitro inhibitory activity of compounds against human MOGAT-2 is evaluated in this assay. MOGAT-2 transfers an oleoyl group to monooleoyl-glyce...				US Patent US8993568 (2015) BindingDB Entry DOI: 10.7270/Q2WM1C4M
Eli Lilly and Company US Patent					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM152807 (BDBM152808 \| US8993568, 2) Show SMILES Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	4
Eli Lilly and Company US Patent					Assay Description The in vitro inhibitory activity of compounds against human MOGAT-2 is evaluated in this assay. MOGAT-2 transfers an oleoyl group to monooleoyl-glyce...				US Patent US8993568 (2015) BindingDB Entry DOI: 10.7270/Q2WM1C4M
Eli Lilly and Company US Patent					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM152812 (US8993568, 16) Show SMILES Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	94	n/a	n/a	n/a	n/a	n/a	4
Eli Lilly and Company US Patent					Assay Description The in vitro inhibitory activity of compounds against human MOGAT-2 is evaluated in this assay. MOGAT-2 transfers an oleoyl group to monooleoyl-glyce...				US Patent US8993568 (2015) BindingDB Entry DOI: 10.7270/Q2WM1C4M
Eli Lilly and Company US Patent					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM152810 (US8993568, 11) Show SMILES Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	4
Eli Lilly and Company US Patent					Assay Description The in vitro inhibitory activity of compounds against human MOGAT-2 is evaluated in this assay. MOGAT-2 transfers an oleoyl group to monooleoyl-glyce...				US Patent US8993568 (2015) BindingDB Entry DOI: 10.7270/Q2WM1C4M
Eli Lilly and Company US Patent					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM152807 (BDBM152808 \| US8993568, 2) Show SMILES Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	274	n/a	n/a	n/a	n/a	n/a	4
Eli Lilly and Company US Patent					Assay Description The in vitro inhibitory activity of compounds against human MOGAT-2 is evaluated in this assay. MOGAT-2 transfers an oleoyl group to monooleoyl-glyce...				US Patent US8993568 (2015) BindingDB Entry DOI: 10.7270/Q2WM1C4M
Eli Lilly and Company US Patent					More data for this Ligand-Target Pair

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Change energy units to:kcal/mole

* indicates data uncertainty>20%