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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat)) | BDBM155390 (US9006282, Example 3, Compound 9) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet  | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Redx Pharma Limited US Patent | Assay Description All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP... | US Patent US9006282 (2015) BindingDB Entry DOI: 10.7270/Q28K77T8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat)) | BDBM155389 (US9006282, Example 3, Compound 8) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Redx Pharma Limited US Patent | Assay Description All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP... | US Patent US9006282 (2015) BindingDB Entry DOI: 10.7270/Q28K77T8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat)) | BDBM155380 (US9006282, Example 2, Compound 8 | US9102656, Exam...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Redx Pharma Limited US Patent | Assay Description All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP... | US Patent US9006282 (2015) BindingDB Entry DOI: 10.7270/Q28K77T8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat)) | BDBM155384 (US9006282, Example 3, Compound 3) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Redx Pharma Limited US Patent | Assay Description All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP... | US Patent US9006282 (2015) BindingDB Entry DOI: 10.7270/Q28K77T8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat)) | BDBM155385 (US9006282, Example 3, Compound 4) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Redx Pharma Limited US Patent | Assay Description All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP... | US Patent US9006282 (2015) BindingDB Entry DOI: 10.7270/Q28K77T8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat)) | BDBM155374 (US9006282, Example 2, Compound 2 | US9102656, Exam...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Redx Pharma Limited US Patent | Assay Description All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP... | US Patent US9006282 (2015) BindingDB Entry DOI: 10.7270/Q28K77T8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat)) | BDBM155386 (US9006282, Example 3, Compound 5) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Redx Pharma Limited US Patent | Assay Description All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP... | US Patent US9006282 (2015) BindingDB Entry DOI: 10.7270/Q28K77T8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat)) | BDBM155376 (US9006282, Example 2, Compound 4 | US9102656, Exam...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Redx Pharma Limited US Patent | Assay Description All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP... | US Patent US9006282 (2015) BindingDB Entry DOI: 10.7270/Q28K77T8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat)) | BDBM155382 (US9006282, Example 2, Compound 10 | US9102656, Exa...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Redx Pharma Limited US Patent | Assay Description All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP... | US Patent US9006282 (2015) BindingDB Entry DOI: 10.7270/Q28K77T8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat)) | BDBM155381 (US9006282, Example 2, Compound 9 | US9102656, Exam...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Redx Pharma Limited US Patent | Assay Description All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP... | US Patent US9006282 (2015) BindingDB Entry DOI: 10.7270/Q28K77T8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat)) | BDBM155379 (US9006282, Example 2, Compound 7 | US9102656, Exam...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Redx Pharma Limited US Patent | Assay Description All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP... | US Patent US9006282 (2015) BindingDB Entry DOI: 10.7270/Q28K77T8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat)) | BDBM155378 (US9006282, Example 2, Compound 6 | US9102656, Exam...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Redx Pharma Limited US Patent | Assay Description All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP... | US Patent US9006282 (2015) BindingDB Entry DOI: 10.7270/Q28K77T8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat)) | BDBM50011032 (5-(4-Fluoro-phenyl)-1-[2-(4-hydroxy-6-oxo-tetrahyd...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Redx Pharma Limited US Patent | Assay Description All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP... | US Patent US9006282 (2015) BindingDB Entry DOI: 10.7270/Q28K77T8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat)) | BDBM155388 (US9006282, Example 3, Compound 7) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Redx Pharma Limited US Patent | Assay Description All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP... | US Patent US9006282 (2015) BindingDB Entry DOI: 10.7270/Q28K77T8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat)) | BDBM155387 (US9006282, Example 3, Compound 6) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 4 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Redx Pharma Limited US Patent | Assay Description All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP... | US Patent US9006282 (2015) BindingDB Entry DOI: 10.7270/Q28K77T8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat)) | BDBM155377 (US9006282, Example 2, Compound 5 | US9102656, Exam...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 4 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Redx Pharma Limited US Patent | Assay Description All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP... | US Patent US9006282 (2015) BindingDB Entry DOI: 10.7270/Q28K77T8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat)) | BDBM50371228 (Crestor | ROSUVASTATIN CALCIUM | Rosuvastatin | US...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 4 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Redx Pharma Limited US Patent | Assay Description All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP... | US Patent US9006282 (2015) BindingDB Entry DOI: 10.7270/Q28K77T8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat)) | BDBM50221993 (CHEMBL393220 | Calcium (betaR,deltaR)-2-(p-fluorop...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 7 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Redx Pharma Limited US Patent | Assay Description All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP... | US Patent US9006282 (2015) BindingDB Entry DOI: 10.7270/Q28K77T8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat)) | BDBM155375 (US9006282, Example 2, Compound 3 | US9102656, Exam...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 8 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Redx Pharma Limited US Patent | Assay Description All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP... | US Patent US9006282 (2015) BindingDB Entry DOI: 10.7270/Q28K77T8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rattus norvegicus (rat)) | BDBM155383 (US9006282, Example 2, Compound 11 | US9102656, Exa...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 10 | n/a | n/a | n/a | n/a | 7.2 | n/a |
Redx Pharma Limited US Patent | Assay Description All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP... | US Patent US9006282 (2015) BindingDB Entry DOI: 10.7270/Q28K77T8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
