Affinity Data by Patent

Patent code US9029367

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Beta-secretase 1 (Homo sapiens (Human))	BDBM158179 (US9029367, 3) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6.66	n/a	n/a	n/a	n/a	4.6	25
Eli Lilly and Company US Patent					Assay Description Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten uL of each dilution is ad...				US Patent US9029367 (2015) BindingDB Entry DOI: 10.7270/Q21Z4344
Eli Lilly and Company US Patent					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM158178 (US9029367, 2) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	13.2	n/a	n/a	n/a	n/a	4.6	25
Eli Lilly and Company US Patent					Assay Description Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten uL of each dilution is ad...				US Patent US9029367 (2015) BindingDB Entry DOI: 10.7270/Q21Z4344
Eli Lilly and Company US Patent					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM158177 (US9029367, 1) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	15.6	n/a	n/a	n/a	n/a	4.6	25
Eli Lilly and Company US Patent					Assay Description Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten uL of each dilution is ad...				US Patent US9029367 (2015) BindingDB Entry DOI: 10.7270/Q21Z4344
Eli Lilly and Company US Patent					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM158181 (US9029367, 57) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	25.7	n/a	n/a	n/a	n/a	4.6	25
Eli Lilly and Company US Patent					Assay Description Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten uL of each dilution is ad...				US Patent US9029367 (2015) BindingDB Entry DOI: 10.7270/Q21Z4344
Eli Lilly and Company US Patent					More data for this Ligand-Target Pair
Beta-secretase 1 (Homo sapiens (Human))	BDBM158180 (US9029367, 34) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	45	n/a	n/a	n/a	n/a	4.6	25
Eli Lilly and Company US Patent					Assay Description Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten uL of each dilution is ad...				US Patent US9029367 (2015) BindingDB Entry DOI: 10.7270/Q21Z4344
Eli Lilly and Company US Patent					More data for this Ligand-Target Pair

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Change energy units to:kcal/mole

* indicates data uncertainty>20%