BindingDB logo
myBDB logout

Patent code US9040501

Compile Data Set for Download or QSAR
Found 5 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytidine deaminase


(Homo sapiens (Human))
BDBM159790
PNG
(US9040501, 876400)
Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1CC=CCNC1=O |r,c:12|
Show InChI InChI=1S/C10H16N2O5/c13-5-6-7(14)8(15)9(17-6)12-4-2-1-3-11-10(12)16/h1-2,6-9,13-15H,3-5H2,(H,11,16)/t6-,7-,8-,9-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 101n/an/an/an/a7.4n/a



Otsuka Pharmaceutical Co., Ltd.

US Patent


Assay Description
The cytidine deaminase (CDA) enzymatic assay described by Cacciamani, T. et al., Arch. Biochem. Biophys. 1991, 290, 285-92; Cohen R. et al., J. Biol....


US Patent US9040501 (2015)


BindingDB Entry DOI: 10.7270/Q22R3QD1
More data for this
Ligand-Target Pair
Cytidine deaminase


(Homo sapiens (Human))
BDBM50421666
PNG
(CHEMBL2311128 | US9040501, 876404)
Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1CCC(O)NC1=O
Show InChI InChI=1S/C9H16N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h4-8,12-15H,1-3H2,(H,10,16)/t4-,5?,6-,7-,8-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 113n/an/an/an/a7.4n/a



Otsuka Pharmaceutical Co., Ltd.

US Patent


Assay Description
The cytidine deaminase (CDA) enzymatic assay described by Cacciamani, T. et al., Arch. Biochem. Biophys. 1991, 290, 285-92; Cohen R. et al., J. Biol....


US Patent US9040501 (2015)


BindingDB Entry DOI: 10.7270/Q22R3QD1
More data for this
Ligand-Target Pair
Cytidine deaminase


(Homo sapiens (Human))
BDBM159792
PNG
(US9040501, 878895)
Show SMILES OC[C@H]1O[C@H]([C@@H](F)[C@@H]1O)N1CC=CCNC1=O |r,c:12|
Show InChI InChI=1S/C10H15FN2O4/c11-7-8(15)6(5-14)17-9(7)13-4-2-1-3-12-10(13)16/h1-2,6-9,14-15H,3-5H2,(H,12,16)/t6-,7+,8-,9-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 140n/an/an/an/a7.4n/a



Otsuka Pharmaceutical Co., Ltd.

US Patent


Assay Description
The cytidine deaminase (CDA) enzymatic assay described by Cacciamani, T. et al., Arch. Biochem. Biophys. 1991, 290, 285-92; Cohen R. et al., J. Biol....


US Patent US9040501 (2015)


BindingDB Entry DOI: 10.7270/Q22R3QD1
More data for this
Ligand-Target Pair
Cytidine deaminase


(Homo sapiens (Human))
BDBM159789
PNG
(US9040501, 876437)
Show SMILES OC[C@H]1O[C@@H](N2CC=CCNC2=O)C(F)(F)[C@@H]1O |r,c:7|
Show InChI InChI=1S/C10H14F2N2O4/c11-10(12)7(16)6(5-15)18-8(10)14-4-2-1-3-13-9(14)17/h1-2,6-8,15-16H,3-5H2,(H,13,17)/t6-,7-,8-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 237n/an/an/an/a7.4n/a



Otsuka Pharmaceutical Co., Ltd.

US Patent


Assay Description
The cytidine deaminase (CDA) enzymatic assay described by Cacciamani, T. et al., Arch. Biochem. Biophys. 1991, 290, 285-92; Cohen R. et al., J. Biol....


US Patent US9040501 (2015)


BindingDB Entry DOI: 10.7270/Q22R3QD1
More data for this
Ligand-Target Pair
Cytidine deaminase


(Homo sapiens (Human))
BDBM159791
PNG
(US9040501, 878519)
Show SMILES OC[C@H]1O[C@H](N2CC=CCNC2=O)C(F)(F)[C@@H]1O |r,c:7|
Show InChI InChI=1S/C10H14F2N2O4/c11-10(12)7(16)6(5-15)18-8(10)14-4-2-1-3-13-9(14)17/h1-2,6-8,15-16H,3-5H2,(H,13,17)/t6-,7-,8+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 1.62E+3n/an/an/an/a7.4n/a



Otsuka Pharmaceutical Co., Ltd.

US Patent


Assay Description
The cytidine deaminase (CDA) enzymatic assay described by Cacciamani, T. et al., Arch. Biochem. Biophys. 1991, 290, 285-92; Cohen R. et al., J. Biol....


US Patent US9040501 (2015)


BindingDB Entry DOI: 10.7270/Q22R3QD1
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%