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Patent code US9051321

Compile Data Set for Download or QSAR
Found 28 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI


(Staphylococcus aureus)		BDBM133668
PNG
(US8846711, 12 | US9051321, 12)
Show SMILES O=C(\C=C\c1cnc2NC(=O)CCc2c1)N1CC(C1)OCc1cccs1
Show InChI InChI=1S/C19H19N3O3S/c23-17-5-4-14-8-13(9-20-19(14)21-17)3-6-18(24)22-10-15(11-22)25-12-16-2-1-7-26-16/h1-3,6-9,15H,4-5,10-12H2,(H,20,21,23)/b6-3+
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n/an/a 13n/an/an/an/a6.525



FAB PHARMA S.A.S.

US Patent


Assay Description
The assay buffer "AB" contained 50 mM ADA (N-(2-acetamido)iminodiacetic acid monosodium salt) pH 6.5, 1 mM dithiothreitol, 0.006% Triton-X100 and 50 ...

US Patent US9051321 (2015)


BindingDB Entry DOI: 10.7270/Q2WW7GDG
More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI


(Staphylococcus aureus)		BDBM133671
PNG
(US8846711, 15 | US9051321, 15)
Show SMILES CCCCCOC1CN(C1)C(=O)\C=C\c1cnc2NC(=O)CCc2c1
Show InChI InChI=1S/C19H25N3O3/c1-2-3-4-9-25-16-12-22(13-16)18(24)8-5-14-10-15-6-7-17(23)21-19(15)20-11-14/h5,8,10-11,16H,2-4,6-7,9,12-13H2,1H3,(H,20,21,23)/b8-5+
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n/an/a 25n/an/an/an/a6.525



FAB PHARMA S.A.S.

US Patent


Assay Description
The assay buffer "AB" contained 50 mM ADA (N-(2-acetamido)iminodiacetic acid monosodium salt) pH 6.5, 1 mM dithiothreitol, 0.006% Triton-X100 and 50 ...

US Patent US9051321 (2015)


BindingDB Entry DOI: 10.7270/Q2WW7GDG
More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI


(Staphylococcus aureus)		BDBM133664
PNG
(US8846711, 8 | US9051321, 8)
Show SMILES CCCC1CCN(CC1)C(=O)\C=C\c1cnc2NC(=O)CCc2c1
Show InChI InChI=1S/C19H25N3O2/c1-2-3-14-8-10-22(11-9-14)18(24)7-4-15-12-16-5-6-17(23)21-19(16)20-13-15/h4,7,12-14H,2-3,5-6,8-11H2,1H3,(H,20,21,23)/b7-4+
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n/an/a 41n/an/an/an/a6.525



FAB PHARMA S.A.S.

US Patent


Assay Description
The assay buffer "AB" contained 50 mM ADA (N-(2-acetamido)iminodiacetic acid monosodium salt) pH 6.5, 1 mM dithiothreitol, 0.006% Triton-X100 and 50 ...

US Patent US9051321 (2015)


BindingDB Entry DOI: 10.7270/Q2WW7GDG
More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI


(Staphylococcus aureus)		BDBM133673
PNG
(US8846711, 17 | US9051321, 17)
Show SMILES O=C(\C=C\c1cnc2NC(=O)CCc2c1)N1CC(C1)OCc1ccccc1
Show InChI InChI=1S/C21H21N3O3/c25-19-8-7-17-10-16(11-22-21(17)23-19)6-9-20(26)24-12-18(13-24)27-14-15-4-2-1-3-5-15/h1-6,9-11,18H,7-8,12-14H2,(H,22,23,25)/b9-6+
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n/an/a 50n/an/an/an/a6.525



FAB PHARMA S.A.S.

US Patent


Assay Description
The assay buffer "AB" contained 50 mM ADA (N-(2-acetamido)iminodiacetic acid monosodium salt) pH 6.5, 1 mM dithiothreitol, 0.006% Triton-X100 and 50 ...

US Patent US9051321 (2015)


BindingDB Entry DOI: 10.7270/Q2WW7GDG
More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI


(Staphylococcus aureus)		BDBM133676
PNG
(US8846711, 20 | US9051321, 20)
Show SMILES O=C(\C=C\c1cnc2NC(=O)CCc2c1)N1CC(C1)OCc1nccs1
Show InChI InChI=1S/C18H18N4O3S/c23-15-3-2-13-7-12(8-20-18(13)21-15)1-4-17(24)22-9-14(10-22)25-11-16-19-5-6-26-16/h1,4-8,14H,2-3,9-11H2,(H,20,21,23)/b4-1+
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n/an/a 57n/an/an/an/a6.525



FAB PHARMA S.A.S.

US Patent


Assay Description
The assay buffer "AB" contained 50 mM ADA (N-(2-acetamido)iminodiacetic acid monosodium salt) pH 6.5, 1 mM dithiothreitol, 0.006% Triton-X100 and 50 ...

US Patent US9051321 (2015)


BindingDB Entry DOI: 10.7270/Q2WW7GDG
More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI


(Staphylococcus aureus)		BDBM133681
PNG
(US8846711, 25 | US8846711, 26 | US9051321, 25)
Show SMILES COC(=O)C1Cc2cc(\C=C\C(=O)N3CCC(COc4ccc(F)cc4)CC3)cnc2NC1=O
Show InChI InChI=1S/C25H26FN3O5/c1-33-25(32)21-13-18-12-17(14-27-23(18)28-24(21)31)2-7-22(30)29-10-8-16(9-11-29)15-34-20-5-3-19(26)4-6-20/h2-7,12,14,16,21H,8-11,13,15H2,1H3,(H,27,28,31)/b7-2+
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n/an/a 60n/an/an/an/a6.525



FAB PHARMA S.A.S.

US Patent


Assay Description
The assay buffer "AB" contained 50 mM ADA (N-(2-acetamido)iminodiacetic acid monosodium salt) pH 6.5, 1 mM dithiothreitol, 0.006% Triton-X100 and 50 ...

US Patent US9051321 (2015)


BindingDB Entry DOI: 10.7270/Q2WW7GDG
More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI


(Staphylococcus aureus)		BDBM9913
PNG
(US8846711, 26 | US9051321, 27)
Show SMILES NC(=O)C1Cc2cc(\C=C\C(=O)N3CCC(COc4ccc(F)cc4)CC3)cnc2NC1=O
Show InChI InChI=1S/C24H25FN4O4/c25-18-2-4-19(5-3-18)33-14-15-7-9-29(10-8-15)21(30)6-1-16-11-17-12-20(22(26)31)24(32)28-23(17)27-13-16/h1-6,11,13,15,20H,7-10,12,14H2,(H2,26,31)(H,27,28,32)/b6-1+
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n/an/a 78n/an/an/an/a6.525



FAB PHARMA S.A.S.

US Patent


Assay Description
The assay buffer "AB" contained 50 mM ADA (N-(2-acetamido)iminodiacetic acid monosodium salt) pH 6.5, 1 mM dithiothreitol, 0.006% Triton-X100 and 50 ...

US Patent US9051321 (2015)


BindingDB Entry DOI: 10.7270/Q2WW7GDG
More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI


(Staphylococcus aureus)		BDBM133683
PNG
(US8846711, 28 | US9051321, 28)
Show SMILES OCC1Cc2cc(\C=C\C(=O)N3CCC(COc4ccc(F)cc4)CC3)cnc2NC1=O
Show InChI InChI=1S/C24H26FN3O4/c25-20-2-4-21(5-3-20)32-15-16-7-9-28(10-8-16)22(30)6-1-17-11-18-12-19(14-29)24(31)27-23(18)26-13-17/h1-6,11,13,16,19,29H,7-10,12,14-15H2,(H,26,27,31)/b6-1+
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n/an/a 81n/an/an/an/a6.525



FAB PHARMA S.A.S.

US Patent


Assay Description
The assay buffer "AB" contained 50 mM ADA (N-(2-acetamido)iminodiacetic acid monosodium salt) pH 6.5, 1 mM dithiothreitol, 0.006% Triton-X100 and 50 ...

US Patent US9051321 (2015)


BindingDB Entry DOI: 10.7270/Q2WW7GDG
More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI


(Staphylococcus aureus)		BDBM133666
PNG
(US8846711, 10 | US9051321, 10)
Show SMILES O=C(\C=C\c1cnc2NC(=O)CCc2c1)N1CCC(C1)Oc1ccccc1
Show InChI InChI=1S/C21H21N3O3/c25-19-8-7-16-12-15(13-22-21(16)23-19)6-9-20(26)24-11-10-18(14-24)27-17-4-2-1-3-5-17/h1-6,9,12-13,18H,7-8,10-11,14H2,(H,22,23,25)/b9-6+
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n/an/a 120n/an/an/an/a6.525



FAB PHARMA S.A.S.

US Patent


Assay Description
The assay buffer "AB" contained 50 mM ADA (N-(2-acetamido)iminodiacetic acid monosodium salt) pH 6.5, 1 mM dithiothreitol, 0.006% Triton-X100 and 50 ...

US Patent US9051321 (2015)


BindingDB Entry DOI: 10.7270/Q2WW7GDG
More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI


(Staphylococcus aureus)		BDBM162339
PNG
(US9051321, 11)
Show SMILES Cc1nc(no1)C1CN(C1)C(=O)\C=C\c1cnc2NC(=O)CCc2c1
Show InChI InChI=1S/C17H17N5O3/c1-10-19-17(21-25-10)13-8-22(9-13)15(24)5-2-11-6-12-3-4-14(23)20-16(12)18-7-11/h2,5-7,13H,3-4,8-9H2,1H3,(H,18,20,23)/b5-2+
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n/an/a 150n/an/an/an/a6.525



FAB PHARMA S.A.S.

US Patent


Assay Description
The assay buffer "AB" contained 50 mM ADA (N-(2-acetamido)iminodiacetic acid monosodium salt) pH 6.5, 1 mM dithiothreitol, 0.006% Triton-X100 and 50 ...

US Patent US9051321 (2015)


BindingDB Entry DOI: 10.7270/Q2WW7GDG
More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI


(Staphylococcus aureus)		BDBM133675
PNG
(US8846711, 19 | US9051321, 19)
Show SMILES CC(=C)COC1CN(C1)C(=O)\C=C\c1cnc2NC(=O)CCc2c1
Show InChI InChI=1S/C18H21N3O3/c1-12(2)11-24-15-9-21(10-15)17(23)6-3-13-7-14-4-5-16(22)20-18(14)19-8-13/h3,6-8,15H,1,4-5,9-11H2,2H3,(H,19,20,22)/b6-3+
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n/an/a 170n/an/an/an/a6.525



FAB PHARMA S.A.S.

US Patent


Assay Description
The assay buffer "AB" contained 50 mM ADA (N-(2-acetamido)iminodiacetic acid monosodium salt) pH 6.5, 1 mM dithiothreitol, 0.006% Triton-X100 and 50 ...

US Patent US9051321 (2015)


BindingDB Entry DOI: 10.7270/Q2WW7GDG
More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI


(Staphylococcus aureus)		BDBM133661
PNG
(US8846711, 5 | US9051321, 5)
Show SMILES CC(C)(C)OC(=O)N1CCC(COc2ccc(F)cc2)CC1
Show InChI InChI=1S/C17H24FNO3/c1-17(2,3)22-16(20)19-10-8-13(9-11-19)12-21-15-6-4-14(18)5-7-15/h4-7,13H,8-12H2,1-3H3
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n/an/a 250n/an/an/an/a6.525



FAB PHARMA S.A.S.

US Patent


Assay Description
The assay buffer "AB" contained 50 mM ADA (N-(2-acetamido)iminodiacetic acid monosodium salt) pH 6.5, 1 mM dithiothreitol, 0.006% Triton-X100 and 50 ...

US Patent US9051321 (2015)


BindingDB Entry DOI: 10.7270/Q2WW7GDG
More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI


(Staphylococcus aureus)		BDBM133680
PNG
(US8846711, 24 | US9051321, 24)
Show SMILES CC(=O)Nc1ccc(\C=C\C(=O)N2CC(C2)OCc2ccncc2)cn1
Show InChI InChI=1S/C19H20N4O3/c1-14(24)22-18-4-2-15(10-21-18)3-5-19(25)23-11-17(12-23)26-13-16-6-8-20-9-7-16/h2-10,17H,11-13H2,1H3,(H,21,22,24)/b5-3+
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n/an/a 260n/an/an/an/a6.525



FAB PHARMA S.A.S.

US Patent


Assay Description
The assay buffer "AB" contained 50 mM ADA (N-(2-acetamido)iminodiacetic acid monosodium salt) pH 6.5, 1 mM dithiothreitol, 0.006% Triton-X100 and 50 ...

US Patent US9051321 (2015)


BindingDB Entry DOI: 10.7270/Q2WW7GDG
More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI


(Staphylococcus aureus)		BDBM133670
PNG
(US8846711, 14 | US9051321, 14)
Show SMILES OC1(CCN(CC1)C(=O)\C=C\c1cnc2NC(=O)CCc2c1)c1ccccc1
Show InChI InChI=1S/C22H23N3O3/c26-19-8-7-17-14-16(15-23-21(17)24-19)6-9-20(27)25-12-10-22(28,11-13-25)18-4-2-1-3-5-18/h1-6,9,14-15,28H,7-8,10-13H2,(H,23,24,26)/b9-6+
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n/an/a 340n/an/an/an/a6.525



FAB PHARMA S.A.S.

US Patent


Assay Description
The assay buffer "AB" contained 50 mM ADA (N-(2-acetamido)iminodiacetic acid monosodium salt) pH 6.5, 1 mM dithiothreitol, 0.006% Triton-X100 and 50 ...

US Patent US9051321 (2015)


BindingDB Entry DOI: 10.7270/Q2WW7GDG
More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI


(Staphylococcus aureus)		BDBM9913
PNG
(US8846711, 26 | US9051321, 27)
Show SMILES NC(=O)C1Cc2cc(\C=C\C(=O)N3CCC(COc4ccc(F)cc4)CC3)cnc2NC1=O
Show InChI InChI=1S/C24H25FN4O4/c25-18-2-4-19(5-3-18)33-14-15-7-9-29(10-8-15)21(30)6-1-16-11-17-12-20(22(26)31)24(32)28-23(17)27-13-16/h1-6,11,13,15,20H,7-10,12,14H2,(H2,26,31)(H,27,28,32)/b6-1+
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n/an/a 550n/an/an/an/a6.525



FAB PHARMA S.A.S.

US Patent


Assay Description
The assay buffer "AB" contained 50 mM ADA (N-(2-acetamido)iminodiacetic acid monosodium salt) pH 6.5, 1 mM dithiothreitol, 0.006% Triton-X100 and 50 ...

US Patent US9051321 (2015)


BindingDB Entry DOI: 10.7270/Q2WW7GDG
More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI


(Staphylococcus aureus)		BDBM133677
PNG
(US8846711, 21 | US9051321, 21)
Show SMILES C\C(Cc1ncccn1)=N/OC1CN(C1)C(=O)\C=C\c1cnc2NC(=O)CCc2c1 |w:10.10|
Show InChI InChI=1S/C21H22N6O3/c1-14(9-18-22-7-2-8-23-18)26-30-17-12-27(13-17)20(29)6-3-15-10-16-4-5-19(28)25-21(16)24-11-15/h2-3,6-8,10-11,17H,4-5,9,12-13H2,1H3,(H,24,25,28)/b6-3+,26-14+
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n/an/a 870n/an/an/an/a6.525



FAB PHARMA S.A.S.

US Patent


Assay Description
The assay buffer "AB" contained 50 mM ADA (N-(2-acetamido)iminodiacetic acid monosodium salt) pH 6.5, 1 mM dithiothreitol, 0.006% Triton-X100 and 50 ...

US Patent US9051321 (2015)


BindingDB Entry DOI: 10.7270/Q2WW7GDG
More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI


(Staphylococcus aureus)		BDBM133672
PNG
(US8846711, 16 | US9051321, 16)
Show SMILES O=C(\C=C\c1cnc2NC(=O)CCc2c1)N1CCC(C1)Oc1cccnc1
Show InChI InChI=1S/C20H20N4O3/c25-18-5-4-15-10-14(11-22-20(15)23-18)3-6-19(26)24-9-7-17(13-24)27-16-2-1-8-21-12-16/h1-3,6,8,10-12,17H,4-5,7,9,13H2,(H,22,23,25)/b6-3+
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n/an/a 930n/an/an/an/a6.525



FAB PHARMA S.A.S.

US Patent


Assay Description
The assay buffer "AB" contained 50 mM ADA (N-(2-acetamido)iminodiacetic acid monosodium salt) pH 6.5, 1 mM dithiothreitol, 0.006% Triton-X100 and 50 ...

US Patent US9051321 (2015)


BindingDB Entry DOI: 10.7270/Q2WW7GDG
More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI


(Staphylococcus aureus)		BDBM162329
PNG
(US9051321, 6)
Show SMILES O=C(\C=C\c1cnc2NC(=O)CCc2c1)N1CC(C1)Oc1ccccc1
Show InChI InChI=1S/C20H19N3O3/c24-18-8-7-15-10-14(11-21-20(15)22-18)6-9-19(25)23-12-17(13-23)26-16-4-2-1-3-5-16/h1-6,9-11,17H,7-8,12-13H2,(H,21,22,24)/b9-6+
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n/an/a 1.00E+3n/an/an/an/a6.525



FAB PHARMA S.A.S.

US Patent


Assay Description
The assay buffer "AB" contained 50 mM ADA (N-(2-acetamido)iminodiacetic acid monosodium salt) pH 6.5, 1 mM dithiothreitol, 0.006% Triton-X100 and 50 ...

US Patent US9051321 (2015)


BindingDB Entry DOI: 10.7270/Q2WW7GDG
More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI


(Staphylococcus aureus)		BDBM162330
PNG
(US9051321, 9)
Show SMILES Fc1ccc(OCC2CCCN(C2)C(=O)\C=C\c2cnc3NC(=O)CCc3c2)cc1
Show InChI InChI=1S/C23H24FN3O3/c24-19-5-7-20(8-6-19)30-15-17-2-1-11-27(14-17)22(29)10-3-16-12-18-4-9-21(28)26-23(18)25-13-16/h3,5-8,10,12-13,17H,1-2,4,9,11,14-15H2,(H,25,26,28)/b10-3+
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n/an/a 1.30E+3n/an/an/an/a6.525



FAB PHARMA S.A.S.

US Patent


Assay Description
The assay buffer "AB" contained 50 mM ADA (N-(2-acetamido)iminodiacetic acid monosodium salt) pH 6.5, 1 mM dithiothreitol, 0.006% Triton-X100 and 50 ...

US Patent US9051321 (2015)


BindingDB Entry DOI: 10.7270/Q2WW7GDG
More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI


(Staphylococcus aureus)		BDBM133679
PNG
(US8846711, 23 | US9051321, 23)
Show SMILES Nc1ccc(\C=C\C(=O)N2CC(C2)OCc2ccncc2)cn1
Show InChI InChI=1S/C17H18N4O2/c18-16-3-1-13(9-20-16)2-4-17(22)21-10-15(11-21)23-12-14-5-7-19-8-6-14/h1-9,15H,10-12H2,(H2,18,20)/b4-2+
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n/an/a 1.80E+3n/an/an/an/a6.525



FAB PHARMA S.A.S.

US Patent


Assay Description
The assay buffer "AB" contained 50 mM ADA (N-(2-acetamido)iminodiacetic acid monosodium salt) pH 6.5, 1 mM dithiothreitol, 0.006% Triton-X100 and 50 ...

US Patent US9051321 (2015)


BindingDB Entry DOI: 10.7270/Q2WW7GDG
More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI


(Staphylococcus aureus)		BDBM133674
PNG
(US8846711, 18 | US9051321, 18)
Show SMILES O=C(\C=C\c1cnc2NC(=O)CCc2c1)N1CCCC[C@@H]1c1nc2ccccc2o1 |r|
Show InChI InChI=1S/C23H22N4O3/c28-20-10-9-16-13-15(14-24-22(16)26-20)8-11-21(29)27-12-4-3-6-18(27)23-25-17-5-1-2-7-19(17)30-23/h1-2,5,7-8,11,13-14,18H,3-4,6,9-10,12H2,(H,24,26,28)/b11-8+/t18-/m1/s1
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FAB PHARMA S.A.S.

US Patent


Assay Description
The assay buffer "AB" contained 50 mM ADA (N-(2-acetamido)iminodiacetic acid monosodium salt) pH 6.5, 1 mM dithiothreitol, 0.006% Triton-X100 and 50 ...

US Patent US9051321 (2015)


BindingDB Entry DOI: 10.7270/Q2WW7GDG
More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI


(Staphylococcus aureus)		BDBM133669
PNG
(US8846711, 13 | US9051321, 13)
Show SMILES Cc1nc(no1)C1CCCCN1C(=O)\C=C\c1cnc2NC(=O)CCc2c1
Show InChI InChI=1S/C19H21N5O3/c1-12-21-19(23-27-12)15-4-2-3-9-24(15)17(26)8-5-13-10-14-6-7-16(25)22-18(14)20-11-13/h5,8,10-11,15H,2-4,6-7,9H2,1H3,(H,20,22,25)/b8-5+
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FAB PHARMA S.A.S.

US Patent


Assay Description
The assay buffer "AB" contained 50 mM ADA (N-(2-acetamido)iminodiacetic acid monosodium salt) pH 6.5, 1 mM dithiothreitol, 0.006% Triton-X100 and 50 ...

US Patent US9051321 (2015)


BindingDB Entry DOI: 10.7270/Q2WW7GDG
More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI


(Staphylococcus aureus)		BDBM133660
PNG
(US8846711, 4 | US9051321, 4)
Show SMILES OCCC1CCN(CC1)C(=O)\C=C\c1cnc2NC(=O)CCc2c1
Show InChI InChI=1S/C18H23N3O3/c22-10-7-13-5-8-21(9-6-13)17(24)4-1-14-11-15-2-3-16(23)20-18(15)19-12-14/h1,4,11-13,22H,2-3,5-10H2,(H,19,20,23)/b4-1+
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FAB PHARMA S.A.S.

US Patent


Assay Description
The assay buffer "AB" contained 50 mM ADA (N-(2-acetamido)iminodiacetic acid monosodium salt) pH 6.5, 1 mM dithiothreitol, 0.006% Triton-X100 and 50 ...

US Patent US9051321 (2015)


BindingDB Entry DOI: 10.7270/Q2WW7GDG
More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI


(Staphylococcus aureus)		BDBM133658
PNG
(US8846711, 2 | US9051321, 2)
Show SMILES O=C(\C=C\c1cnc2NC(=O)CCc2c1)N1CCCC1
Show InChI InChI=1S/C15H17N3O2/c19-13-5-4-12-9-11(10-16-15(12)17-13)3-6-14(20)18-7-1-2-8-18/h3,6,9-10H,1-2,4-5,7-8H2,(H,16,17,19)/b6-3+
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FAB PHARMA S.A.S.

US Patent


Assay Description
The assay buffer "AB" contained 50 mM ADA (N-(2-acetamido)iminodiacetic acid monosodium salt) pH 6.5, 1 mM dithiothreitol, 0.006% Triton-X100 and 50 ...

US Patent US9051321 (2015)


BindingDB Entry DOI: 10.7270/Q2WW7GDG
More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI


(Staphylococcus aureus)		BDBM133663
PNG
(US8846711, 7 | US9051321, 7)
Show SMILES O=C(\C=C\c1cnc2NC(=O)CCc2c1)N1CCCC1c1ccccc1
Show InChI InChI=1S/C21H21N3O2/c25-19-10-9-17-13-15(14-22-21(17)23-19)8-11-20(26)24-12-4-7-18(24)16-5-2-1-3-6-16/h1-3,5-6,8,11,13-14,18H,4,7,9-10,12H2,(H,22,23,25)/b11-8+
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FAB PHARMA S.A.S.

US Patent


Assay Description
The assay buffer "AB" contained 50 mM ADA (N-(2-acetamido)iminodiacetic acid monosodium salt) pH 6.5, 1 mM dithiothreitol, 0.006% Triton-X100 and 50 ...

US Patent US9051321 (2015)


BindingDB Entry DOI: 10.7270/Q2WW7GDG
More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI


(Staphylococcus aureus)		BDBM133678
PNG
(US8846711, 22 | US9051321, 22)
Show SMILES CCCCCS(=O)(=O)C1CN(C1)C(=O)\C=C\c1cnc2NC(=O)CCc2c1
Show InChI InChI=1S/C19H25N3O4S/c1-2-3-4-9-27(25,26)16-12-22(13-16)18(24)8-5-14-10-15-6-7-17(23)21-19(15)20-11-14/h5,8,10-11,16H,2-4,6-7,9,12-13H2,1H3,(H,20,21,23)/b8-5+
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FAB PHARMA S.A.S.

US Patent


Assay Description
The assay buffer "AB" contained 50 mM ADA (N-(2-acetamido)iminodiacetic acid monosodium salt) pH 6.5, 1 mM dithiothreitol, 0.006% Triton-X100 and 50 ...

US Patent US9051321 (2015)


BindingDB Entry DOI: 10.7270/Q2WW7GDG
More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI


(Staphylococcus aureus)		BDBM133659
PNG
(US8846711, 3 | US9051321, 3 | US9598407, Compound ...)
Show SMILES O=C(\C=C\c1cnc2NC(=O)CCc2c1)N1CCCCC1
Show InChI InChI=1S/C16H19N3O2/c20-14-6-5-13-10-12(11-17-16(13)18-14)4-7-15(21)19-8-2-1-3-9-19/h4,7,10-11H,1-3,5-6,8-9H2,(H,17,18,20)/b7-4+
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FAB PHARMA S.A.S.

US Patent


Assay Description
The assay buffer "AB" contained 50 mM ADA (N-(2-acetamido)iminodiacetic acid monosodium salt) pH 6.5, 1 mM dithiothreitol, 0.006% Triton-X100 and 50 ...

US Patent US9051321 (2015)


BindingDB Entry DOI: 10.7270/Q2WW7GDG
More data for this
Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI


(Staphylococcus aureus)		BDBM133657
PNG
(US8846711, 1 | US9051321, 1)
Show SMILES O=C(\C=C\c1cnc2NC(=O)CCc2c1)N1CCC1
Show InChI InChI=1S/C14H15N3O2/c18-12-4-3-11-8-10(9-15-14(11)16-12)2-5-13(19)17-6-1-7-17/h2,5,8-9H,1,3-4,6-7H2,(H,15,16,18)/b5-2+
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FAB PHARMA S.A.S.

US Patent


Assay Description
The assay buffer "AB" contained 50 mM ADA (N-(2-acetamido)iminodiacetic acid monosodium salt) pH 6.5, 1 mM dithiothreitol, 0.006% Triton-X100 and 50 ...

US Patent US9051321 (2015)


BindingDB Entry DOI: 10.7270/Q2WW7GDG
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%