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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (Homo sapiens (Human)) | BDBM123687 (US8741907, 3 | US9067945, 2) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet  | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 110 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Boehringer Ingehleim International GmbH US Patent | Assay Description The test substances are dissolved in 100% DMSO and serially diluted to determine their in vitro effect on PDE 9A. Typically, serial dilutions from 20... | US Patent US9067945 (2015) BindingDB Entry DOI: 10.7270/Q2708052 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Homo sapiens (Human)) | BDBM123687 (US8741907, 3 | US9067945, 2) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 720 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Boehringer Ingehleim International GmbH US Patent | Assay Description The test substances are dissolved in 100% DMSO and serially diluted to determine their in vitro effect on PDE 9A. Typically, serial dilutions from 20... | US Patent US9067945 (2015) BindingDB Entry DOI: 10.7270/Q2708052 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B (Homo sapiens (Human)) | BDBM123687 (US8741907, 3 | US9067945, 2) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Boehringer Ingehleim International GmbH US Patent | Assay Description The test substances are dissolved in 100% DMSO and serially diluted to determine their in vitro effect on PDE 9A. Typically, serial dilutions from 20... | US Patent US9067945 (2015) BindingDB Entry DOI: 10.7270/Q2708052 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 7B (Homo sapiens (Human)) | BDBM123687 (US8741907, 3 | US9067945, 2) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Boehringer Ingehleim International GmbH US Patent | Assay Description The test substances are dissolved in 100% DMSO and serially diluted to determine their in vitro effect on PDE 9A. Typically, serial dilutions from 20... | US Patent US9067945 (2015) BindingDB Entry DOI: 10.7270/Q2708052 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human)) | BDBM123687 (US8741907, 3 | US9067945, 2) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Boehringer Ingehleim International GmbH US Patent | Assay Description The test substances are dissolved in 100% DMSO and serially diluted to determine their in vitro effect on PDE 9A. Typically, serial dilutions from 20... | US Patent US9067945 (2015) BindingDB Entry DOI: 10.7270/Q2708052 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (Homo sapiens (Human)) | BDBM123687 (US8741907, 3 | US9067945, 2) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Boehringer Ingehleim International GmbH US Patent | Assay Description The test substances are dissolved in 100% DMSO and serially diluted to determine their in vitro effect on PDE 9A. Typically, serial dilutions from 20... | US Patent US9067945 (2015) BindingDB Entry DOI: 10.7270/Q2708052 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (Homo sapiens (Human)) | BDBM123687 (US8741907, 3 | US9067945, 2) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Boehringer Ingehleim International GmbH US Patent | Assay Description The test substances are dissolved in 100% DMSO and serially diluted to determine their in vitro effect on PDE 9A. Typically, serial dilutions from 20... | US Patent US9067945 (2015) BindingDB Entry DOI: 10.7270/Q2708052 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM123687 (US8741907, 3 | US9067945, 2) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Boehringer Ingehleim International GmbH US Patent | Assay Description The test substances are dissolved in 100% DMSO and serially diluted to determine their in vitro effect on PDE 9A. Typically, serial dilutions from 20... | US Patent US9067945 (2015) BindingDB Entry DOI: 10.7270/Q2708052 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM123687 (US8741907, 3 | US9067945, 2) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Boehringer Ingehleim International GmbH US Patent | Assay Description The test substances are dissolved in 100% DMSO and serially diluted to determine their in vitro effect on PDE 9A. Typically, serial dilutions from 20... | US Patent US9067945 (2015) BindingDB Entry DOI: 10.7270/Q2708052 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM123687 (US8741907, 3 | US9067945, 2) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Boehringer Ingehleim International GmbH US Patent | Assay Description The test substances are dissolved in 100% DMSO and serially diluted to determine their in vitro effect on PDE 9A. Typically, serial dilutions from 20... | US Patent US9067945 (2015) BindingDB Entry DOI: 10.7270/Q2708052 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
