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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Aurora kinase A (Homo sapiens (Human)) | BDBM47224 (US9073917, 2-inventive) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet  | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
SANOFI US Patent | Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th... | US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM47224 (US9073917, 2-inventive) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
SANOFI US Patent | Assay Description The effect of the compounds of the invention on the activity of the enzyme PDE3 was evaluated by the company CEREP (Le bois I'Evêque, 86600 Celle... | US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM167515 (US9073917, 12- comparative) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
SANOFI US Patent | Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif... | US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase A (Homo sapiens (Human)) | BDBM167510 (US9073917, 7- comparative) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
SANOFI US Patent | Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif... | US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM167510 (US9073917, 7- comparative) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
SANOFI US Patent | Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif... | US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase A (Homo sapiens (Human)) | BDBM167515 (US9073917, 12- comparative) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
SANOFI US Patent | Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif... | US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM167506 (US9073917, 1-inventive) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
SANOFI US Patent | Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif... | US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM167508 (US9073917, 5- comparative) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
SANOFI US Patent | Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif... | US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase A (Homo sapiens (Human)) | BDBM167506 (US9073917, 1-inventive) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
SANOFI US Patent | Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif... | US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM167507 (US9073917, 4- comparative) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
SANOFI US Patent | Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif... | US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM167512 (US9073917, 11- comparative | US9073917, 9- compara...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
SANOFI US Patent | Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif... | US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM167513 (US9073917, 10- comparative) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
SANOFI US Patent | Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif... | US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM167516 (US9073917, 13- comparative) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
SANOFI US Patent | Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif... | US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase A (Homo sapiens (Human)) | BDBM167516 (US9073917, 13- comparative) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
SANOFI US Patent | Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif... | US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM167509 (US9073917, 6- comparative) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
SANOFI US Patent | Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif... | US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase A (Homo sapiens (Human)) | BDBM167512 (US9073917, 11- comparative | US9073917, 9- compara...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
SANOFI US Patent | Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif... | US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM167511 (US9073917, 8- comparative) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
SANOFI US Patent | Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif... | US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase A (Homo sapiens (Human)) | BDBM167513 (US9073917, 10- comparative) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
SANOFI US Patent | Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif... | US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase A (Homo sapiens (Human)) | BDBM167508 (US9073917, 5- comparative) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
SANOFI US Patent | Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif... | US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (Homo sapiens (Human)) | BDBM167515 (US9073917, 12- comparative) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 68 | n/a | n/a | n/a | n/a | n/a | n/a |
SANOFI US Patent | Assay Description The effect of the compounds of the invention on the activity of the enzyme PDE3 was evaluated by the company CEREP (Le bois I'Evêque, 86600 Celle... | US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase A (Homo sapiens (Human)) | BDBM167507 (US9073917, 4- comparative) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 72 | n/a | n/a | n/a | n/a | n/a | n/a |
SANOFI US Patent | Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif... | US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase A (Homo sapiens (Human)) | BDBM167511 (US9073917, 8- comparative) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 102 | n/a | n/a | n/a | n/a | n/a | n/a |
SANOFI US Patent | Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif... | US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM167512 (US9073917, 11- comparative | US9073917, 9- compara...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 107 | n/a | n/a | n/a | n/a | n/a | n/a |
SANOFI US Patent | Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif... | US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase A (Homo sapiens (Human)) | BDBM167509 (US9073917, 6- comparative) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 109 | n/a | n/a | n/a | n/a | n/a | n/a |
SANOFI US Patent | Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif... | US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase A (Homo sapiens (Human)) | BDBM60452 (US9073917, 3-comparative) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
SANOFI US Patent | Assay Description The effect of the compounds of the invention on the activity of the enzyme PDE3 was evaluated by the company CEREP (Le bois I'Evêque, 86600 Celle... | US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase A (Homo sapiens (Human)) | BDBM167512 (US9073917, 11- comparative | US9073917, 9- compara...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.76E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SANOFI US Patent | Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif... | US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Aurora kinase B/Inner centromere protein (Homo sapiens (Human)) | BDBM60452 (US9073917, 3-comparative) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SANOFI US Patent | Assay Description The effect of the compounds of the invention on the activity of the enzyme PDE3 was evaluated by the company CEREP (Le bois I'Evêque, 86600 Celle... | US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
