Affinity Data by Patent

Patent code US9079852

Found 20 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM168618 (US9079852, Table F, Compound 3) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	553	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Emory University; NeurOp, Inc. US Patent					Assay Description Compounds were evaluated for binding to the human ether-a-go-go potassium channel (hERG) expressed in HEK293 cells by displacement of 3[H]-astemizole...				US Patent US9079852 (2015) BindingDB Entry DOI: 10.7270/Q2K35SF5
Emory University; NeurOp, Inc. US Patent					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM168620 (US9079852, Table F, Compound 5) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Emory University; NeurOp, Inc. US Patent					Assay Description Compounds were evaluated for binding to the human ether-a-go-go potassium channel (hERG) expressed in HEK293 cells by displacement of 3[H]-astemizole...				US Patent US9079852 (2015) BindingDB Entry DOI: 10.7270/Q2K35SF5
Emory University; NeurOp, Inc. US Patent					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM168617 (US9079852, Table F, Compound 2) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Emory University; NeurOp, Inc. US Patent					Assay Description Compounds were evaluated for binding to the human ether-a-go-go potassium channel (hERG) expressed in HEK293 cells by displacement of 3[H]-astemizole...				US Patent US9079852 (2015) BindingDB Entry DOI: 10.7270/Q2K35SF5
Emory University; NeurOp, Inc. US Patent					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM168626 (US9079852, Table F, Compound 11) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Emory University; NeurOp, Inc. US Patent					Assay Description Compounds were evaluated for binding to the human ether-a-go-go potassium channel (hERG) expressed in HEK293 cells by displacement of 3[H]-astemizole...				US Patent US9079852 (2015) BindingDB Entry DOI: 10.7270/Q2K35SF5
Emory University; NeurOp, Inc. US Patent					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM168625 (US9079852, Table F, Compound 10) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Emory University; NeurOp, Inc. US Patent					Assay Description Compounds were evaluated for binding to the human ether-a-go-go potassium channel (hERG) expressed in HEK293 cells by displacement of 3[H]-astemizole...				US Patent US9079852 (2015) BindingDB Entry DOI: 10.7270/Q2K35SF5
Emory University; NeurOp, Inc. US Patent					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM168621 (US9079852, Table F, Compound 6) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Emory University; NeurOp, Inc. US Patent					Assay Description Compounds were evaluated for binding to the human ether-a-go-go potassium channel (hERG) expressed in HEK293 cells by displacement of 3[H]-astemizole...				US Patent US9079852 (2015) BindingDB Entry DOI: 10.7270/Q2K35SF5
Emory University; NeurOp, Inc. US Patent					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM168622 (US9079852, Table F, Compound 7) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Emory University; NeurOp, Inc. US Patent					Assay Description Compounds were evaluated for binding to the human ether-a-go-go potassium channel (hERG) expressed in HEK293 cells by displacement of 3[H]-astemizole...				US Patent US9079852 (2015) BindingDB Entry DOI: 10.7270/Q2K35SF5
Emory University; NeurOp, Inc. US Patent					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM168624 (US9079852, Table F, Compound 9) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Emory University; NeurOp, Inc. US Patent					Assay Description Compounds were evaluated for binding to the human ether-a-go-go potassium channel (hERG) expressed in HEK293 cells by displacement of 3[H]-astemizole...				US Patent US9079852 (2015) BindingDB Entry DOI: 10.7270/Q2K35SF5
Emory University; NeurOp, Inc. US Patent					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM168619 (US9079852, Table F, Compound 4) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Emory University; NeurOp, Inc. US Patent					Assay Description Compounds were evaluated for binding to the human ether-a-go-go potassium channel (hERG) expressed in HEK293 cells by displacement of 3[H]-astemizole...				US Patent US9079852 (2015) BindingDB Entry DOI: 10.7270/Q2K35SF5
Emory University; NeurOp, Inc. US Patent					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM168616 (US9079852, Table F, Compound 1) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	3.90E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Emory University; NeurOp, Inc. US Patent					Assay Description Compounds were evaluated for binding to the human ether-a-go-go potassium channel (hERG) expressed in HEK293 cells by displacement of 3[H]-astemizole...				US Patent US9079852 (2015) BindingDB Entry DOI: 10.7270/Q2K35SF5
Emory University; NeurOp, Inc. US Patent					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM168624 (US9079852, Table F, Compound 9) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Emory University; NeurOp, Inc. US Patent					Assay Description Binding to the rat alpha-1 adrenergic receptor in rat brain membranes was determined by displacement of 3[H]-prazosin (P. Greengrass and R. Bremner; ...				US Patent US9079852 (2015) BindingDB Entry DOI: 10.7270/Q2K35SF5
Emory University; NeurOp, Inc. US Patent					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM168626 (US9079852, Table F, Compound 11) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Emory University; NeurOp, Inc. US Patent					Assay Description Binding to the rat alpha-1 adrenergic receptor in rat brain membranes was determined by displacement of 3[H]-prazosin (P. Greengrass and R. Bremner; ...				US Patent US9079852 (2015) BindingDB Entry DOI: 10.7270/Q2K35SF5
Emory University; NeurOp, Inc. US Patent					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM168625 (US9079852, Table F, Compound 10) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Emory University; NeurOp, Inc. US Patent					Assay Description Binding to the rat alpha-1 adrenergic receptor in rat brain membranes was determined by displacement of 3[H]-prazosin (P. Greengrass and R. Bremner; ...				US Patent US9079852 (2015) BindingDB Entry DOI: 10.7270/Q2K35SF5
Emory University; NeurOp, Inc. US Patent					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM168620 (US9079852, Table F, Compound 5) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Emory University; NeurOp, Inc. US Patent					Assay Description Binding to the rat alpha-1 adrenergic receptor in rat brain membranes was determined by displacement of 3[H]-prazosin (P. Greengrass and R. Bremner; ...				US Patent US9079852 (2015) BindingDB Entry DOI: 10.7270/Q2K35SF5
Emory University; NeurOp, Inc. US Patent					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM168619 (US9079852, Table F, Compound 4) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Emory University; NeurOp, Inc. US Patent					Assay Description Binding to the rat alpha-1 adrenergic receptor in rat brain membranes was determined by displacement of 3[H]-prazosin (P. Greengrass and R. Bremner; ...				US Patent US9079852 (2015) BindingDB Entry DOI: 10.7270/Q2K35SF5
Emory University; NeurOp, Inc. US Patent					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM168618 (US9079852, Table F, Compound 3) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Emory University; NeurOp, Inc. US Patent					Assay Description Binding to the rat alpha-1 adrenergic receptor in rat brain membranes was determined by displacement of 3[H]-prazosin (P. Greengrass and R. Bremner; ...				US Patent US9079852 (2015) BindingDB Entry DOI: 10.7270/Q2K35SF5
Emory University; NeurOp, Inc. US Patent					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM168621 (US9079852, Table F, Compound 6) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Emory University; NeurOp, Inc. US Patent					Assay Description Binding to the rat alpha-1 adrenergic receptor in rat brain membranes was determined by displacement of 3[H]-prazosin (P. Greengrass and R. Bremner; ...				US Patent US9079852 (2015) BindingDB Entry DOI: 10.7270/Q2K35SF5
Emory University; NeurOp, Inc. US Patent					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM168622 (US9079852, Table F, Compound 7) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Emory University; NeurOp, Inc. US Patent					Assay Description Binding to the rat alpha-1 adrenergic receptor in rat brain membranes was determined by displacement of 3[H]-prazosin (P. Greengrass and R. Bremner; ...				US Patent US9079852 (2015) BindingDB Entry DOI: 10.7270/Q2K35SF5
Emory University; NeurOp, Inc. US Patent					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM168617 (US9079852, Table F, Compound 2) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
Emory University; NeurOp, Inc. US Patent					Assay Description Binding to the rat alpha-1 adrenergic receptor in rat brain membranes was determined by displacement of 3[H]-prazosin (P. Greengrass and R. Bremner; ...				US Patent US9079852 (2015) BindingDB Entry DOI: 10.7270/Q2K35SF5
Emory University; NeurOp, Inc. US Patent					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM168616 (US9079852, Table F, Compound 1) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	720	n/a	n/a	n/a	n/a	n/a	n/a
Emory University; NeurOp, Inc. US Patent					Assay Description Binding to the rat alpha-1 adrenergic receptor in rat brain membranes was determined by displacement of 3[H]-prazosin (P. Greengrass and R. Bremner; ...				US Patent US9079852 (2015) BindingDB Entry DOI: 10.7270/Q2K35SF5
Emory University; NeurOp, Inc. US Patent					More data for this Ligand-Target Pair

Reorder this table by EC50
Reorder this table by IC50
Reorder this table by Kd
Reorder this table by KON
Reorder this table by KOFF
Reorder this table by pH
Reorder this table by T
Reorder this table by ΔH°
Reorder this table by -TΔS°
Change energy units to:kcal/mole

* indicates data uncertainty>20%