Affinity Data by Patent

Patent code US9108950

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM161376 (US10238658, Example 1 \| US10813932, Example 1 \| US...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Respivert, Ltd. US Patent					Assay Description The kinase enzyme binding activities of compounds disclosed herein were determined using a proprietary assay which measures active site-directed comp...				US Patent US9108950 (2015) BindingDB Entry DOI: 10.7270/Q2697293
Respivert, Ltd. US Patent					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM161376 (US10238658, Example 1 \| US10813932, Example 1 \| US...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Respivert, Ltd. US Patent					Assay Description The kinase enzyme binding activities of compounds disclosed herein were determined using a proprietary assay which measures active site-directed comp...				US Patent US9108950 (2015) BindingDB Entry DOI: 10.7270/Q2697293
Respivert, Ltd. US Patent					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM161376 (US10238658, Example 1 \| US10813932, Example 1 \| US...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	334	n/a	n/a	n/a	n/a	n/a	n/a
Respivert, Ltd. US Patent					Assay Description The kinase enzyme binding activities of compounds disclosed herein were determined using a proprietary assay which measures active site-directed comp...				US Patent US9108950 (2015) BindingDB Entry DOI: 10.7270/Q2697293
Respivert, Ltd. US Patent					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 12 (Homo sapiens (Human))	BDBM161376 (US10238658, Example 1 \| US10813932, Example 1 \| US...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
Respivert, Ltd. US Patent					Assay Description The kinase enzyme binding activities of compounds disclosed herein were determined using a proprietary assay which measures active site-directed comp...				US Patent US9108950 (2015) BindingDB Entry DOI: 10.7270/Q2697293
Respivert, Ltd. US Patent					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM161376 (US10238658, Example 1 \| US10813932, Example 1 \| US...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Respivert, Ltd. US Patent					Assay Description The kinase enzyme binding activities of compounds disclosed herein were determined using a proprietary assay which measures active site-directed comp...				US Patent US9108950 (2015) BindingDB Entry DOI: 10.7270/Q2697293
Respivert, Ltd. US Patent					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM161376 (US10238658, Example 1 \| US10813932, Example 1 \| US...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a
Respivert, Ltd. US Patent					Assay Description The kinase enzyme binding activities of compounds disclosed herein were determined using a proprietary assay which measures active site-directed comp...				US Patent US9108950 (2015) BindingDB Entry DOI: 10.7270/Q2697293
Respivert, Ltd. US Patent					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM161376 (US10238658, Example 1 \| US10813932, Example 1 \| US...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a
Respivert, Ltd. US Patent					Assay Description The kinase enzyme binding activities of compounds disclosed herein were determined using a proprietary assay which measures active site-directed comp...				US Patent US9108950 (2015) BindingDB Entry DOI: 10.7270/Q2697293
Respivert, Ltd. US Patent					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM161376 (US10238658, Example 1 \| US10813932, Example 1 \| US...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a
Respivert, Ltd. US Patent					Assay Description The kinase enzyme binding activities of compounds disclosed herein were determined using a proprietary assay which measures active site-directed comp...				US Patent US9108950 (2015) BindingDB Entry DOI: 10.7270/Q2697293
Respivert, Ltd. US Patent					More data for this Ligand-Target Pair
Tyrosine-protein kinase HCK (Homo sapiens (Human))	BDBM161376 (US10238658, Example 1 \| US10813932, Example 1 \| US...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a
Respivert, Ltd. US Patent					Assay Description The kinase enzyme binding activities of compounds disclosed herein were determined using a proprietary assay which measures active site-directed comp...				US Patent US9108950 (2015) BindingDB Entry DOI: 10.7270/Q2697293
Respivert, Ltd. US Patent					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 12 (Homo sapiens (Human))	BDBM161376 (US10238658, Example 1 \| US10813932, Example 1 \| US...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a
Respivert, Ltd. US Patent					Assay Description The kinase enzyme binding activities of compounds disclosed herein were determined using a proprietary assay which measures active site-directed comp...				US Patent US9108950 (2015) BindingDB Entry DOI: 10.7270/Q2697293
Respivert, Ltd. US Patent					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM161376 (US10238658, Example 1 \| US10813932, Example 1 \| US...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a
Respivert, Ltd. US Patent					Assay Description The kinase enzyme binding activities of compounds disclosed herein were determined using a proprietary assay which measures active site-directed comp...				US Patent US9108950 (2015) BindingDB Entry DOI: 10.7270/Q2697293
Respivert, Ltd. US Patent					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM161376 (US10238658, Example 1 \| US10813932, Example 1 \| US...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a
Respivert, Ltd. US Patent					Assay Description The kinase enzyme binding activities of compounds disclosed herein were determined using a proprietary assay which measures active site-directed comp...				US Patent US9108950 (2015) BindingDB Entry DOI: 10.7270/Q2697293
Respivert, Ltd. US Patent					More data for this Ligand-Target Pair

Reorder this table by EC50
Reorder this table by IC50
Reorder this table by Kd
Reorder this table by KON
Reorder this table by KOFF
Reorder this table by pH
Reorder this table by T
Reorder this table by ΔH°
Reorder this table by -TΔS°
Change energy units to:kcal/mole

* indicates data uncertainty>20%