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Patent code US9126979

Compile Data Set for Download or QSAR
Found 24 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM179548
PNG
(US9126979, 5)
Show SMILES CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1cc(OCC(O)=O)ccc1C(=O)N1Cc2ccccc2C[C@H]1CO |r|
Show InChI InChI=1S/C32H40N4O6/c1-4-6-14-34(15-7-5-2)32(41)28-16-22(3)36(33-28)29-18-26(42-21-30(38)39)12-13-27(29)31(40)35-19-24-11-9-8-10-23(24)17-25(35)20-37/h8-13,16,18,25,37H,4-7,14-15,17,19-21H2,1-3H3,(H,38,39)/t25-/m0/s1
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n/an/a 84.8n/an/an/an/an/a25



Novartis AG

US Patent


Assay Description
Biacore utilizes the phenomenon of surface plasmon resonance (SPR) to detect and measure binding interactions. In a typical Biacore experiment, one o...

US Patent US9126979 (2015)


BindingDB Entry DOI: 10.7270/Q2WS8S1M
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM179548
PNG
(US9126979, 5)
Show SMILES CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1cc(OCC(O)=O)ccc1C(=O)N1Cc2ccccc2C[C@H]1CO |r|
Show InChI InChI=1S/C32H40N4O6/c1-4-6-14-34(15-7-5-2)32(41)28-16-22(3)36(33-28)29-18-26(42-21-30(38)39)12-13-27(29)31(40)35-19-24-11-9-8-10-23(24)17-25(35)20-37/h8-13,16,18,25,37H,4-7,14-15,17,19-21H2,1-3H3,(H,38,39)/t25-/m0/s1
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n/an/a 102n/an/an/an/an/a25



Novartis AG

US Patent


Assay Description
Biacore utilizes the phenomenon of surface plasmon resonance (SPR) to detect and measure binding interactions. In a typical Biacore experiment, one o...

US Patent US9126979 (2015)


BindingDB Entry DOI: 10.7270/Q2WS8S1M
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM179545
PNG
(US9126979, 2)
Show SMILES CCCCN(CCCC)C(=O)c1nn(c(C)c1Cl)-c1ccc(OCC(O)=O)cc1C(=O)N1Cc2ccccc2C[C@H]1CO |r|
Show InChI InChI=1S/C32H39ClN4O6/c1-4-6-14-35(15-7-5-2)32(42)30-29(33)21(3)37(34-30)27-13-12-25(43-20-28(39)40)17-26(27)31(41)36-18-23-11-9-8-10-22(23)16-24(36)19-38/h8-13,17,24,38H,4-7,14-16,18-20H2,1-3H3,(H,39,40)/t24-/m0/s1
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n/an/a 135n/an/an/an/an/a25



Novartis AG

US Patent


Assay Description
Biacore utilizes the phenomenon of surface plasmon resonance (SPR) to detect and measure binding interactions. In a typical Biacore experiment, one o...

US Patent US9126979 (2015)


BindingDB Entry DOI: 10.7270/Q2WS8S1M
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM179545
PNG
(US9126979, 2)
Show SMILES CCCCN(CCCC)C(=O)c1nn(c(C)c1Cl)-c1ccc(OCC(O)=O)cc1C(=O)N1Cc2ccccc2C[C@H]1CO |r|
Show InChI InChI=1S/C32H39ClN4O6/c1-4-6-14-35(15-7-5-2)32(42)30-29(33)21(3)37(34-30)27-13-12-25(43-20-28(39)40)17-26(27)31(41)36-18-23-11-9-8-10-22(23)16-24(36)19-38/h8-13,17,24,38H,4-7,14-16,18-20H2,1-3H3,(H,39,40)/t24-/m0/s1
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n/an/a 151n/an/an/an/an/a25



Novartis AG

US Patent


Assay Description
Biacore utilizes the phenomenon of surface plasmon resonance (SPR) to detect and measure binding interactions. In a typical Biacore experiment, one o...

US Patent US9126979 (2015)


BindingDB Entry DOI: 10.7270/Q2WS8S1M
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM179554
PNG
(US9126979, 11)
Show SMILES CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1cc(O)ccc1C(=O)N1Cc2ccccc2C[C@H]1CO |r|
Show InChI InChI=1S/C30H38N4O4/c1-4-6-14-32(15-7-5-2)30(38)27-16-21(3)34(31-27)28-18-25(36)12-13-26(28)29(37)33-19-23-11-9-8-10-22(23)17-24(33)20-35/h8-13,16,18,24,35-36H,4-7,14-15,17,19-20H2,1-3H3/t24-/m0/s1
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n/an/a 247n/an/an/an/an/a25



Novartis AG

US Patent


Assay Description
Biacore utilizes the phenomenon of surface plasmon resonance (SPR) to detect and measure binding interactions. In a typical Biacore experiment, one o...

US Patent US9126979 (2015)


BindingDB Entry DOI: 10.7270/Q2WS8S1M
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM179554
PNG
(US9126979, 11)
Show SMILES CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1cc(O)ccc1C(=O)N1Cc2ccccc2C[C@H]1CO |r|
Show InChI InChI=1S/C30H38N4O4/c1-4-6-14-32(15-7-5-2)30(38)27-16-21(3)34(31-27)28-18-25(36)12-13-26(28)29(37)33-19-23-11-9-8-10-22(23)17-24(33)20-35/h8-13,16,18,24,35-36H,4-7,14-15,17,19-20H2,1-3H3/t24-/m0/s1
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n/an/a 278n/an/an/an/an/a25



Novartis AG

US Patent


Assay Description
Biacore utilizes the phenomenon of surface plasmon resonance (SPR) to detect and measure binding interactions. In a typical Biacore experiment, one o...

US Patent US9126979 (2015)


BindingDB Entry DOI: 10.7270/Q2WS8S1M
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM179555
PNG
(US9126979, 12)
Show SMILES CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1cc(OC)ccc1C(=O)N1Cc2ccccc2C[C@H]1CO |r|
Show InChI InChI=1S/C31H40N4O4/c1-5-7-15-33(16-8-6-2)31(38)28-17-22(3)35(32-28)29-19-26(39-4)13-14-27(29)30(37)34-20-24-12-10-9-11-23(24)18-25(34)21-36/h9-14,17,19,25,36H,5-8,15-16,18,20-21H2,1-4H3/t25-/m0/s1
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n/an/a 283n/an/an/an/an/a25



Novartis AG

US Patent


Assay Description
Biacore utilizes the phenomenon of surface plasmon resonance (SPR) to detect and measure binding interactions. In a typical Biacore experiment, one o...

US Patent US9126979 (2015)


BindingDB Entry DOI: 10.7270/Q2WS8S1M
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM179544
PNG
(US9126979, 1)
Show SMILES CCCCN(CCCC)C(=O)c1nn(c(C)c1Cl)-c1ccc(OCC(=O)OCC)cc1C(=O)N1Cc2ccccc2C[C@H]1CO |r|
Show InChI InChI=1S/C34H43ClN4O6/c1-5-8-16-37(17-9-6-2)34(43)32-31(35)23(4)39(36-32)29-15-14-27(45-22-30(41)44-7-3)19-28(29)33(42)38-20-25-13-11-10-12-24(25)18-26(38)21-40/h10-15,19,26,40H,5-9,16-18,20-22H2,1-4H3/t26-/m0/s1
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n/an/a 384n/an/an/an/an/a25



Novartis AG

US Patent


Assay Description
Biacore utilizes the phenomenon of surface plasmon resonance (SPR) to detect and measure binding interactions. In a typical Biacore experiment, one o...

US Patent US9126979 (2015)


BindingDB Entry DOI: 10.7270/Q2WS8S1M
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM179546
PNG
(US9126979, 3)
Show SMILES CCCCN(CCCC)C(=O)c1nn(c(C)c1Cl)-c1ccc(OCC(=O)Nc2ccccc2)cc1C(=O)N1Cc2ccccc2C[C@H]1CO |r|
Show InChI InChI=1S/C38H44ClN5O5/c1-4-6-19-42(20-7-5-2)38(48)36-35(39)26(3)44(41-36)33-18-17-31(49-25-34(46)40-29-15-9-8-10-16-29)22-32(33)37(47)43-23-28-14-12-11-13-27(28)21-30(43)24-45/h8-18,22,30,45H,4-7,19-21,23-25H2,1-3H3,(H,40,46)/t30-/m0/s1
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n/an/a 421n/an/an/an/an/a25



Novartis AG

US Patent


Assay Description
Biacore utilizes the phenomenon of surface plasmon resonance (SPR) to detect and measure binding interactions. In a typical Biacore experiment, one o...

US Patent US9126979 (2015)


BindingDB Entry DOI: 10.7270/Q2WS8S1M
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM179552
PNG
(US9126979, 9)
Show SMILES CCCCN(CCCC)C(=O)c1nn(c(C)c1Cl)-c1ccc(O)cc1C(=O)N1Cc2ccccc2C[C@H]1CO |r|
Show InChI InChI=1S/C30H37ClN4O4/c1-4-6-14-33(15-7-5-2)30(39)28-27(31)20(3)35(32-28)26-13-12-24(37)17-25(26)29(38)34-18-22-11-9-8-10-21(22)16-23(34)19-36/h8-13,17,23,36-37H,4-7,14-16,18-19H2,1-3H3/t23-/m0/s1
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n/an/a 422n/an/an/an/an/a25



Novartis AG

US Patent


Assay Description
Biacore utilizes the phenomenon of surface plasmon resonance (SPR) to detect and measure binding interactions. In a typical Biacore experiment, one o...

US Patent US9126979 (2015)


BindingDB Entry DOI: 10.7270/Q2WS8S1M
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM179546
PNG
(US9126979, 3)
Show SMILES CCCCN(CCCC)C(=O)c1nn(c(C)c1Cl)-c1ccc(OCC(=O)Nc2ccccc2)cc1C(=O)N1Cc2ccccc2C[C@H]1CO |r|
Show InChI InChI=1S/C38H44ClN5O5/c1-4-6-19-42(20-7-5-2)38(48)36-35(39)26(3)44(41-36)33-18-17-31(49-25-34(46)40-29-15-9-8-10-16-29)22-32(33)37(47)43-23-28-14-12-11-13-27(28)21-30(43)24-45/h8-18,22,30,45H,4-7,19-21,23-25H2,1-3H3,(H,40,46)/t30-/m0/s1
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n/an/a 455n/an/an/an/an/a25



Novartis AG

US Patent


Assay Description
Biacore utilizes the phenomenon of surface plasmon resonance (SPR) to detect and measure binding interactions. In a typical Biacore experiment, one o...

US Patent US9126979 (2015)


BindingDB Entry DOI: 10.7270/Q2WS8S1M
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM179555
PNG
(US9126979, 12)
Show SMILES CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1cc(OC)ccc1C(=O)N1Cc2ccccc2C[C@H]1CO |r|
Show InChI InChI=1S/C31H40N4O4/c1-5-7-15-33(16-8-6-2)31(38)28-17-22(3)35(32-28)29-19-26(39-4)13-14-27(29)30(37)34-20-24-12-10-9-11-23(24)18-25(34)21-36/h9-14,17,19,25,36H,5-8,15-16,18,20-21H2,1-4H3/t25-/m0/s1
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n/an/a 470n/an/an/an/an/a25



Novartis AG

US Patent


Assay Description
Biacore utilizes the phenomenon of surface plasmon resonance (SPR) to detect and measure binding interactions. In a typical Biacore experiment, one o...

US Patent US9126979 (2015)


BindingDB Entry DOI: 10.7270/Q2WS8S1M
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM179544
PNG
(US9126979, 1)
Show SMILES CCCCN(CCCC)C(=O)c1nn(c(C)c1Cl)-c1ccc(OCC(=O)OCC)cc1C(=O)N1Cc2ccccc2C[C@H]1CO |r|
Show InChI InChI=1S/C34H43ClN4O6/c1-5-8-16-37(17-9-6-2)34(43)32-31(35)23(4)39(36-32)29-15-14-27(45-22-30(41)44-7-3)19-28(29)33(42)38-20-25-13-11-10-12-24(25)18-26(38)21-40/h10-15,19,26,40H,5-9,16-18,20-22H2,1-4H3/t26-/m0/s1
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n/an/a 512n/an/an/an/an/a25



Novartis AG

US Patent


Assay Description
Biacore utilizes the phenomenon of surface plasmon resonance (SPR) to detect and measure binding interactions. In a typical Biacore experiment, one o...

US Patent US9126979 (2015)


BindingDB Entry DOI: 10.7270/Q2WS8S1M
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM179552
PNG
(US9126979, 9)
Show SMILES CCCCN(CCCC)C(=O)c1nn(c(C)c1Cl)-c1ccc(O)cc1C(=O)N1Cc2ccccc2C[C@H]1CO |r|
Show InChI InChI=1S/C30H37ClN4O4/c1-4-6-14-33(15-7-5-2)30(39)28-27(31)20(3)35(32-28)26-13-12-24(37)17-25(26)29(38)34-18-22-11-9-8-10-21(22)16-23(34)19-36/h8-13,17,23,36-37H,4-7,14-16,18-19H2,1-3H3/t23-/m0/s1
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n/an/a 624n/an/an/an/an/a25



Novartis AG

US Patent


Assay Description
Biacore utilizes the phenomenon of surface plasmon resonance (SPR) to detect and measure binding interactions. In a typical Biacore experiment, one o...

US Patent US9126979 (2015)


BindingDB Entry DOI: 10.7270/Q2WS8S1M
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM179547
PNG
(US9126979, 4)
Show SMILES CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1cc(OCC(=O)OCC)ccc1C(=O)N1Cc2ccccc2C[C@H]1CO |r|
Show InChI InChI=1S/C34H44N4O6/c1-5-8-16-36(17-9-6-2)34(42)30-18-24(4)38(35-30)31-20-28(44-23-32(40)43-7-3)14-15-29(31)33(41)37-21-26-13-11-10-12-25(26)19-27(37)22-39/h10-15,18,20,27,39H,5-9,16-17,19,21-23H2,1-4H3/t27-/m0/s1
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n/an/a 773n/an/an/an/an/a25



Novartis AG

US Patent


Assay Description
Biacore utilizes the phenomenon of surface plasmon resonance (SPR) to detect and measure binding interactions. In a typical Biacore experiment, one o...

US Patent US9126979 (2015)


BindingDB Entry DOI: 10.7270/Q2WS8S1M
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM179553
PNG
(US9126979, 10)
Show SMILES CCCCN(CCCC)C(=O)c1nn(c(C)c1Cl)-c1ccc(OC)cc1C(=O)N1Cc2ccccc2C[C@H]1CO |r|
Show InChI InChI=1S/C31H39ClN4O4/c1-5-7-15-34(16-8-6-2)31(39)29-28(32)21(3)36(33-29)27-14-13-25(40-4)18-26(27)30(38)35-19-23-12-10-9-11-22(23)17-24(35)20-37/h9-14,18,24,37H,5-8,15-17,19-20H2,1-4H3/t24-/m0/s1
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n/an/a 892n/an/an/an/an/a25



Novartis AG

US Patent


Assay Description
Biacore utilizes the phenomenon of surface plasmon resonance (SPR) to detect and measure binding interactions. In a typical Biacore experiment, one o...

US Patent US9126979 (2015)


BindingDB Entry DOI: 10.7270/Q2WS8S1M
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM179547
PNG
(US9126979, 4)
Show SMILES CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1cc(OCC(=O)OCC)ccc1C(=O)N1Cc2ccccc2C[C@H]1CO |r|
Show InChI InChI=1S/C34H44N4O6/c1-5-8-16-36(17-9-6-2)34(42)30-18-24(4)38(35-30)31-20-28(44-23-32(40)43-7-3)14-15-29(31)33(41)37-21-26-13-11-10-12-25(26)19-27(37)22-39/h10-15,18,20,27,39H,5-9,16-17,19,21-23H2,1-4H3/t27-/m0/s1
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n/an/a 1.27E+3n/an/an/an/an/a25



Novartis AG

US Patent


Assay Description
Biacore utilizes the phenomenon of surface plasmon resonance (SPR) to detect and measure binding interactions. In a typical Biacore experiment, one o...

US Patent US9126979 (2015)


BindingDB Entry DOI: 10.7270/Q2WS8S1M
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM179550
PNG
(US9126979, 7)
Show SMILES CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1cc(OCC(=O)OCc2ccccc2)ccc1C(=O)N1Cc2ccccc2C[C@H]1CO |r|
Show InChI InChI=1S/C39H46N4O6/c1-4-6-19-41(20-7-5-2)39(47)35-21-28(3)43(40-35)36-23-33(48-27-37(45)49-26-29-13-9-8-10-14-29)17-18-34(36)38(46)42-24-31-16-12-11-15-30(31)22-32(42)25-44/h8-18,21,23,32,44H,4-7,19-20,22,24-27H2,1-3H3/t32-/m0/s1
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n/an/a 1.28E+3n/an/an/an/an/a25



Novartis AG

US Patent


Assay Description
Biacore utilizes the phenomenon of surface plasmon resonance (SPR) to detect and measure binding interactions. In a typical Biacore experiment, one o...

US Patent US9126979 (2015)


BindingDB Entry DOI: 10.7270/Q2WS8S1M
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM179549
PNG
(US9126979, 6)
Show SMILES CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1cc(OCC(=O)Nc2ccccc2)ccc1C(=O)N1Cc2ccccc2C[C@H]1CO |r|
Show InChI InChI=1S/C38H45N5O5/c1-4-6-19-41(20-7-5-2)38(47)34-21-27(3)43(40-34)35-23-32(48-26-36(45)39-30-15-9-8-10-16-30)17-18-33(35)37(46)42-24-29-14-12-11-13-28(29)22-31(42)25-44/h8-18,21,23,31,44H,4-7,19-20,22,24-26H2,1-3H3,(H,39,45)/t31-/m0/s1
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n/an/a 1.29E+3n/an/an/an/an/a25



Novartis AG

US Patent


Assay Description
Biacore utilizes the phenomenon of surface plasmon resonance (SPR) to detect and measure binding interactions. In a typical Biacore experiment, one o...

US Patent US9126979 (2015)


BindingDB Entry DOI: 10.7270/Q2WS8S1M
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM179553
PNG
(US9126979, 10)
Show SMILES CCCCN(CCCC)C(=O)c1nn(c(C)c1Cl)-c1ccc(OC)cc1C(=O)N1Cc2ccccc2C[C@H]1CO |r|
Show InChI InChI=1S/C31H39ClN4O4/c1-5-7-15-34(16-8-6-2)31(39)29-28(32)21(3)36(33-29)27-14-13-25(40-4)18-26(27)30(38)35-19-23-12-10-9-11-22(23)17-24(35)20-37/h9-14,18,24,37H,5-8,15-17,19-20H2,1-4H3/t24-/m0/s1
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n/an/a 1.53E+3n/an/an/an/an/a25



Novartis AG

US Patent


Assay Description
Biacore utilizes the phenomenon of surface plasmon resonance (SPR) to detect and measure binding interactions. In a typical Biacore experiment, one o...

US Patent US9126979 (2015)


BindingDB Entry DOI: 10.7270/Q2WS8S1M
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM179550
PNG
(US9126979, 7)
Show SMILES CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1cc(OCC(=O)OCc2ccccc2)ccc1C(=O)N1Cc2ccccc2C[C@H]1CO |r|
Show InChI InChI=1S/C39H46N4O6/c1-4-6-19-41(20-7-5-2)39(47)35-21-28(3)43(40-35)36-23-33(48-27-37(45)49-26-29-13-9-8-10-14-29)17-18-34(36)38(46)42-24-31-16-12-11-15-30(31)22-32(42)25-44/h8-18,21,23,32,44H,4-7,19-20,22,24-27H2,1-3H3/t32-/m0/s1
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n/an/a 1.54E+3n/an/an/an/an/a25



Novartis AG

US Patent


Assay Description
Biacore utilizes the phenomenon of surface plasmon resonance (SPR) to detect and measure binding interactions. In a typical Biacore experiment, one o...

US Patent US9126979 (2015)


BindingDB Entry DOI: 10.7270/Q2WS8S1M
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM179551
PNG
(US9126979, 8)
Show SMILES CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1cc(OCC(=O)Nc2ccccc2F)ccc1C(=O)N1Cc2ccccc2C[C@H]1CO |r|
Show InChI InChI=1S/C38H44FN5O5/c1-4-6-18-42(19-7-5-2)38(48)34-20-26(3)44(41-34)35-22-30(49-25-36(46)40-33-15-11-10-14-32(33)39)16-17-31(35)37(47)43-23-28-13-9-8-12-27(28)21-29(43)24-45/h8-17,20,22,29,45H,4-7,18-19,21,23-25H2,1-3H3,(H,40,46)/t29-/m0/s1
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n/an/a 1.72E+3n/an/an/an/an/a25



Novartis AG

US Patent


Assay Description
Biacore utilizes the phenomenon of surface plasmon resonance (SPR) to detect and measure binding interactions. In a typical Biacore experiment, one o...

US Patent US9126979 (2015)


BindingDB Entry DOI: 10.7270/Q2WS8S1M
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM179549
PNG
(US9126979, 6)
Show SMILES CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1cc(OCC(=O)Nc2ccccc2)ccc1C(=O)N1Cc2ccccc2C[C@H]1CO |r|
Show InChI InChI=1S/C38H45N5O5/c1-4-6-19-41(20-7-5-2)38(47)34-21-27(3)43(40-34)35-23-32(48-26-36(45)39-30-15-9-8-10-16-30)17-18-33(35)37(46)42-24-29-14-12-11-13-28(29)22-31(42)25-44/h8-18,21,23,31,44H,4-7,19-20,22,24-26H2,1-3H3,(H,39,45)/t31-/m0/s1
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n/an/a 2.09E+3n/an/an/an/an/a25



Novartis AG

US Patent


Assay Description
Biacore utilizes the phenomenon of surface plasmon resonance (SPR) to detect and measure binding interactions. In a typical Biacore experiment, one o...

US Patent US9126979 (2015)


BindingDB Entry DOI: 10.7270/Q2WS8S1M
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM179551
PNG
(US9126979, 8)
Show SMILES CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1cc(OCC(=O)Nc2ccccc2F)ccc1C(=O)N1Cc2ccccc2C[C@H]1CO |r|
Show InChI InChI=1S/C38H44FN5O5/c1-4-6-18-42(19-7-5-2)38(48)34-20-26(3)44(41-34)35-22-30(49-25-36(46)40-33-15-11-10-14-32(33)39)16-17-31(35)37(47)43-23-28-13-9-8-12-27(28)21-29(43)24-45/h8-17,20,22,29,45H,4-7,18-19,21,23-25H2,1-3H3,(H,40,46)/t29-/m0/s1
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n/an/a 2.94E+3n/an/an/an/an/a25



Novartis AG

US Patent


Assay Description
Biacore utilizes the phenomenon of surface plasmon resonance (SPR) to detect and measure binding interactions. In a typical Biacore experiment, one o...

US Patent US9126979 (2015)


BindingDB Entry DOI: 10.7270/Q2WS8S1M
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%