Affinity Data by Patent

Patent code US9133197

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50011300 (CHEMBL2398482 \| US9133197, 2) Show SMILES CC(O)CCc1nc(N)c2nc(-n3nccn3)n(C)c2n1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	US Patent	8	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. US Patent					Assay Description The protein concentration of membrane suspension was determined using the Bradford method (Pierce, Rockford, Ill., USA) with bovine albumin as standa...				US Patent US9133197 (2015) BindingDB Entry DOI: 10.7270/Q2542MB7
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. US Patent					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM181012 (US9133197, 4) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	US Patent	8	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. US Patent					Assay Description The protein concentration of membrane suspension was determined using the Bradford method (Pierce, Rockford, Ill., USA) with bovine albumin as standa...				US Patent US9133197 (2015) BindingDB Entry DOI: 10.7270/Q2542MB7
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. US Patent					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50011301 (CHEMBL2398486 \| US9133197, 7) Show SMILES CC(=O)CCc1nc(N)c2nc(-n3nccn3)n(C)c2n1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	US Patent	12	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. US Patent					Assay Description The protein concentration of membrane suspension was determined using the Bradford method (Pierce, Rockford, Ill., USA) with bovine albumin as standa...				US Patent US9133197 (2015) BindingDB Entry DOI: 10.7270/Q2542MB7
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. US Patent					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM181011 (US9133197, 3) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	US Patent	19	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. US Patent					Assay Description The protein concentration of membrane suspension was determined using the Bradford method (Pierce, Rockford, Ill., USA) with bovine albumin as standa...				US Patent US9133197 (2015) BindingDB Entry DOI: 10.7270/Q2542MB7
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. US Patent					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM181014 (US9133197, 6) Show SMILES CCCC(=O)c1nc(N)c2nc(-n3nccn3)n(C)c2n1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	19	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. US Patent					Assay Description The protein concentration of membrane suspension was determined using the Bradford method (Pierce, Rockford, Ill., USA) with bovine albumin as standa...				US Patent US9133197 (2015) BindingDB Entry DOI: 10.7270/Q2542MB7
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. US Patent					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM181013 (US9133197, 5) Show SMILES CCCC(O)c1nc(N)c2nc(-n3nccn3)n(C)c2n1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	22	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. US Patent					Assay Description The protein concentration of membrane suspension was determined using the Bradford method (Pierce, Rockford, Ill., USA) with bovine albumin as standa...				US Patent US9133197 (2015) BindingDB Entry DOI: 10.7270/Q2542MB7
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. US Patent					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50011300 (CHEMBL2398482 \| US9133197, 2) Show SMILES CC(O)CCc1nc(N)c2nc(-n3nccn3)n(C)c2n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	US Patent	27	-43.2	n/a	n/a	n/a	n/a	n/a	7.4	25
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. US Patent					Assay Description Competition binding experiments have been performed incubating membranes from CHO-K1 cells stably transfected with the human adenosine A1 receptor (c...				US Patent US9133197 (2015) BindingDB Entry DOI: 10.7270/Q2542MB7
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. US Patent					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM181010 (US9133197, 1) Show SMILES Cn1c(nc2c(N)nc(CCCCO)nc12)-n1nccn1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	51	-41.6	n/a	n/a	n/a	n/a	n/a	7.4	25
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. US Patent					Assay Description Competition binding experiments have been performed incubating membranes from CHO-K1 cells stably transfected with the human adenosine A1 receptor (c...				US Patent US9133197 (2015) BindingDB Entry DOI: 10.7270/Q2542MB7
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. US Patent					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM181010 (US9133197, 1) Show SMILES Cn1c(nc2c(N)nc(CCCCO)nc12)-n1nccn1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	53	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. US Patent					Assay Description The protein concentration of membrane suspension was determined using the Bradford method (Pierce, Rockford, Ill., USA) with bovine albumin as standa...				US Patent US9133197 (2015) BindingDB Entry DOI: 10.7270/Q2542MB7
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. US Patent					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM181013 (US9133197, 5) Show SMILES CCCC(O)c1nc(N)c2nc(-n3nccn3)n(C)c2n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	120	-39.5	n/a	n/a	n/a	n/a	n/a	7.4	25
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. US Patent					Assay Description Competition binding experiments have been performed incubating membranes from CHO-K1 cells stably transfected with the human adenosine A1 receptor (c...				US Patent US9133197 (2015) BindingDB Entry DOI: 10.7270/Q2542MB7
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. US Patent					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50011301 (CHEMBL2398486 \| US9133197, 7) Show SMILES CC(=O)CCc1nc(N)c2nc(-n3nccn3)n(C)c2n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	US Patent	197	-38.3	n/a	n/a	n/a	n/a	n/a	7.4	25
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. US Patent					Assay Description Competition binding experiments have been performed incubating membranes from CHO-K1 cells stably transfected with the human adenosine A1 receptor (c...				US Patent US9133197 (2015) BindingDB Entry DOI: 10.7270/Q2542MB7
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. US Patent					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM181014 (US9133197, 6) Show SMILES CCCC(=O)c1nc(N)c2nc(-n3nccn3)n(C)c2n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	216	-38.0	n/a	n/a	n/a	n/a	n/a	7.4	25
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. US Patent					Assay Description Competition binding experiments have been performed incubating membranes from CHO-K1 cells stably transfected with the human adenosine A1 receptor (c...				US Patent US9133197 (2015) BindingDB Entry DOI: 10.7270/Q2542MB7
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. US Patent					More data for this Ligand-Target Pair

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* indicates data uncertainty>20%