Affinity Data by Patent

Patent code US9173879

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM159345 (US9034899, 36 \| US9173879, 1 (-) - enantiomer \| US...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.80	n/a	n/a	n/a	n/a	7.5	25
Bristol-Myers Squibb Company US Patent					Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....				US Patent US9173879 (2015) BindingDB Entry DOI: 10.7270/Q2T72G75
Bristol-Myers Squibb Company US Patent					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM159345 (US9034899, 36 \| US9173879, 1 (-) - enantiomer \| US...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.20	n/a	n/a	n/a	n/a	7.5	25
Bristol-Myers Squibb Company US Patent					Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....				US Patent US9173879 (2015) BindingDB Entry DOI: 10.7270/Q2T72G75
Bristol-Myers Squibb Company US Patent					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM159345 (US9034899, 36 \| US9173879, 1 (-) - enantiomer \| US...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.80	n/a	n/a	n/a	n/a	7.5	4
Bristol-Myers Squibb Company US Patent					Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 1....				US Patent US9173879 (2015) BindingDB Entry DOI: 10.7270/Q2T72G75
Bristol-Myers Squibb Company US Patent					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM159345 (US9034899, 36 \| US9173879, 1 (-) - enantiomer \| US...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	7.5	4
Bristol-Myers Squibb Company US Patent					Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 1....				US Patent US9173879 (2015) BindingDB Entry DOI: 10.7270/Q2T72G75
Bristol-Myers Squibb Company US Patent					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM159345 (US9034899, 36 \| US9173879, 1 (-) - enantiomer \| US...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	30.8	n/a	n/a	n/a	n/a	7.5	4
Bristol-Myers Squibb Company US Patent					Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....				US Patent US9173879 (2015) BindingDB Entry DOI: 10.7270/Q2T72G75
Bristol-Myers Squibb Company US Patent					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM159345 (US9034899, 36 \| US9173879, 1 (-) - enantiomer \| US...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	105	n/a	n/a	n/a	n/a	7.5	4
Bristol-Myers Squibb Company US Patent					Assay Description Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....				US Patent US9173879 (2015) BindingDB Entry DOI: 10.7270/Q2T72G75
Bristol-Myers Squibb Company US Patent					More data for this Ligand-Target Pair

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* indicates data uncertainty>20%