Affinity Data by Patent

Patent code US9187406

Found 25 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Collagenase 3 (Homo sapiens (Human))	BDBM191769 (US11608309, Compound 6 \| US9187406, Compound 6) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	37
The Research Foundation of State University of New York; Chem-Master International, Inc. US Patent					Assay Description It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...				US Patent US9187406 (2015) BindingDB Entry DOI: 10.7270/Q2KH0M3V
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM191770 (US10669227, Compound 7 \| US11608309, Compound 7 \| ...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	37
The Research Foundation of State University of New York; Chem-Master International, Inc. US Patent					Assay Description It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...				US Patent US9187406 (2015) BindingDB Entry DOI: 10.7270/Q2KH0M3V
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50092158 (1,10-phenanthroline \| CHEMBL415879 \| US10669227, C...) Show SMILES c1cnc2c(c1)ccc1cccnc21 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	US Patent	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	37
The Research Foundation of State University of New York; Chem-Master International, Inc. US Patent					Assay Description It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...				US Patent US9187406 (2015) BindingDB Entry DOI: 10.7270/Q2KH0M3V
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM191767 (US11608309, Compound 3 \| US9187406, Compound 3) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	37
The Research Foundation of State University of New York; Chem-Master International, Inc. US Patent					Assay Description It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...				US Patent US9187406 (2015) BindingDB Entry DOI: 10.7270/Q2KH0M3V
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM191767 (US11608309, Compound 3 \| US9187406, Compound 3) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	37
The Research Foundation of State University of New York; Chem-Master International, Inc. US Patent					Assay Description It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...				US Patent US9187406 (2015) BindingDB Entry DOI: 10.7270/Q2KH0M3V
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50092158 (1,10-phenanthroline \| CHEMBL415879 \| US10669227, C...) Show SMILES c1cnc2c(c1)ccc1cccnc21 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	US Patent	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	37
The Research Foundation of State University of New York; Chem-Master International, Inc. US Patent					Assay Description It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...				US Patent US9187406 (2015) BindingDB Entry DOI: 10.7270/Q2KH0M3V
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50092158 (1,10-phenanthroline \| CHEMBL415879 \| US10669227, C...) Show SMILES c1cnc2c(c1)ccc1cccnc21 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	US Patent	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	37
The Research Foundation of State University of New York; Chem-Master International, Inc. US Patent					Assay Description It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...				US Patent US9187406 (2015) BindingDB Entry DOI: 10.7270/Q2KH0M3V
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM191763 (US10669227, Compound Curcumin \| US11608309, Compou...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	37
The Research Foundation of State University of New York; Chem-Master International, Inc. US Patent					Assay Description It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...				US Patent US9187406 (2015) BindingDB Entry DOI: 10.7270/Q2KH0M3V
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM191764 (US9187406, Compound 1) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	37
The Research Foundation of State University of New York; Chem-Master International, Inc. US Patent					Assay Description It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...				US Patent US9187406 (2015) BindingDB Entry DOI: 10.7270/Q2KH0M3V
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM191764 (US9187406, Compound 1) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	37
The Research Foundation of State University of New York; Chem-Master International, Inc. US Patent					Assay Description It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...				US Patent US9187406 (2015) BindingDB Entry DOI: 10.7270/Q2KH0M3V
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM191768 (US9187406, Compound 4) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	37
The Research Foundation of State University of New York; Chem-Master International, Inc. US Patent					Assay Description It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...				US Patent US9187406 (2015) BindingDB Entry DOI: 10.7270/Q2KH0M3V
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM191766 (US9187406, compound 5) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	37
The Research Foundation of State University of New York; Chem-Master International, Inc. US Patent					Assay Description It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...				US Patent US9187406 (2015) BindingDB Entry DOI: 10.7270/Q2KH0M3V
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM191763 (US10669227, Compound Curcumin \| US11608309, Compou...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.90E+4	n/a	n/a	n/a	n/a	n/a	37
The Research Foundation of State University of New York; Chem-Master International, Inc. US Patent					Assay Description It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...				US Patent US9187406 (2015) BindingDB Entry DOI: 10.7270/Q2KH0M3V
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50092158 (1,10-phenanthroline \| CHEMBL415879 \| US10669227, C...) Show SMILES c1cnc2c(c1)ccc1cccnc21 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	US Patent	n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	37
The Research Foundation of State University of New York; Chem-Master International, Inc. US Patent					Assay Description It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...				US Patent US9187406 (2015) BindingDB Entry DOI: 10.7270/Q2KH0M3V
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM191764 (US9187406, Compound 1) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	37
The Research Foundation of State University of New York; Chem-Master International, Inc. US Patent					Assay Description It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...				US Patent US9187406 (2015) BindingDB Entry DOI: 10.7270/Q2KH0M3V
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM191771 (US9187406, Compound 8) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.50E+4	n/a	n/a	n/a	n/a	n/a	37
The Research Foundation of State University of New York; Chem-Master International, Inc. US Patent					Assay Description It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...				US Patent US9187406 (2015) BindingDB Entry DOI: 10.7270/Q2KH0M3V
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM191764 (US9187406, Compound 1) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.80E+4	n/a	n/a	n/a	n/a	n/a	37
The Research Foundation of State University of New York; Chem-Master International, Inc. US Patent					Assay Description It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...				US Patent US9187406 (2015) BindingDB Entry DOI: 10.7270/Q2KH0M3V
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50092158 (1,10-phenanthroline \| CHEMBL415879 \| US10669227, C...) Show SMILES c1cnc2c(c1)ccc1cccnc21 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	US Patent	n/a	n/a	7.00E+4	n/a	n/a	n/a	n/a	n/a	37
The Research Foundation of State University of New York; Chem-Master International, Inc. US Patent					Assay Description It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...				US Patent US9187406 (2015) BindingDB Entry DOI: 10.7270/Q2KH0M3V
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM191767 (US11608309, Compound 3 \| US9187406, Compound 3) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.00E+4	n/a	n/a	n/a	n/a	n/a	37
The Research Foundation of State University of New York; Chem-Master International, Inc. US Patent					Assay Description It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...				US Patent US9187406 (2015) BindingDB Entry DOI: 10.7270/Q2KH0M3V
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM191769 (US11608309, Compound 6 \| US9187406, Compound 6) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8.50E+4	n/a	n/a	n/a	n/a	n/a	37
The Research Foundation of State University of New York; Chem-Master International, Inc. US Patent					Assay Description It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...				US Patent US9187406 (2015) BindingDB Entry DOI: 10.7270/Q2KH0M3V
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM191763 (US10669227, Compound Curcumin \| US11608309, Compou...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8.50E+4	n/a	n/a	n/a	n/a	n/a	37
The Research Foundation of State University of New York; Chem-Master International, Inc. US Patent					Assay Description It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...				US Patent US9187406 (2015) BindingDB Entry DOI: 10.7270/Q2KH0M3V
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM191763 (US10669227, Compound Curcumin \| US11608309, Compou...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.10E+5	n/a	n/a	n/a	n/a	n/a	37
The Research Foundation of State University of New York; Chem-Master International, Inc. US Patent					Assay Description It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...				US Patent US9187406 (2015) BindingDB Entry DOI: 10.7270/Q2KH0M3V
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM191770 (US10669227, Compound 7 \| US11608309, Compound 7 \| ...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.25E+5	n/a	n/a	n/a	n/a	n/a	37
The Research Foundation of State University of New York; Chem-Master International, Inc. US Patent					Assay Description It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...				US Patent US9187406 (2015) BindingDB Entry DOI: 10.7270/Q2KH0M3V
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM191768 (US9187406, Compound 4) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>2.50E+5	n/a	n/a	n/a	n/a	n/a	37
The Research Foundation of State University of New York; Chem-Master International, Inc. US Patent					Assay Description It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...				US Patent US9187406 (2015) BindingDB Entry DOI: 10.7270/Q2KH0M3V
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM191768 (US9187406, Compound 4) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.50E+5	n/a	n/a	n/a	n/a	n/a	37
The Research Foundation of State University of New York; Chem-Master International, Inc. US Patent					Assay Description It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...				US Patent US9187406 (2015) BindingDB Entry DOI: 10.7270/Q2KH0M3V
					More data for this Ligand-Target Pair

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* indicates data uncertainty>20%