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Patent code US9193762

Compile Data Set for Download or QSAR
Found 57 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193289
PNG
(US9193762, RS-42-01)
Show SMILES CCCCCCCCCCCCNC(=O)CCCNC(=O)[C@@H]1CCCN1 |r|
Show InChI InChI=1S/C21H41N3O2/c1-2-3-4-5-6-7-8-9-10-11-16-23-20(25)15-13-18-24-21(26)19-14-12-17-22-19/h19,22H,2-18H2,1H3,(H,23,25)(H,24,26)/t19-/m0/s1
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US Patent
 6.40E+3n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Human pulmonary artery endothelial cells (HPAEC) were purchased from Invitrogen (Carlsbad, Calif.) and were cultured as previously described.20 The c...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193278
PNG
(US9193762, RS-47-06)
Show SMILES CCCCCCCCCCCCNC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCN1
Show InChI InChI=1S/C21H39N3O2/c1-2-3-4-5-6-7-8-9-10-11-15-23-20(25)19-13-12-17-24(19)21(26)18-14-16-22-18/h18-19,22H,2-17H2,1H3,(H,23,25)/t18-,19-/m0/s1
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 1.74E+4n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Human pulmonary artery endothelial cells (HPAEC) were purchased from Invitrogen (Carlsbad, Calif.) and were cultured as previously described.20 The c...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193281
PNG
(US9193762, RS-48-05)
Show SMILES CCCCCCCCCCCCNC(=O)C1CCN1C(=O)C1CCN1
Show InChI InChI=1S/C20H37N3O2/c1-2-3-4-5-6-7-8-9-10-11-14-22-19(24)18-13-16-23(18)20(25)17-12-15-21-17/h17-18,21H,2-16H2,1H3,(H,22,24)
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US Patent
 2.96E+4n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Human pulmonary artery endothelial cells (HPAEC) were purchased from Invitrogen (Carlsbad, Calif.) and were cultured as previously described.20 The c...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193276
PNG
(US9193762, RS-33-21)
Show SMILES CCCCCCCCCCCCNC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1
Show InChI InChI=1S/C22H41N3O2/c1-2-3-4-5-6-7-8-9-10-11-16-24-21(26)20-15-13-18-25(20)22(27)19-14-12-17-23-19/h19-20,23H,2-18H2,1H3,(H,24,26)/t19-,20-/m0/s1
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 3.41E+4n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Human pulmonary artery endothelial cells (HPAEC) were purchased from Invitrogen (Carlsbad, Calif.) and were cultured as previously described.20 The c...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193289
PNG
(US9193762, RS-42-01)
Show SMILES CCCCCCCCCCCCNC(=O)CCCNC(=O)[C@@H]1CCCN1 |r|
Show InChI InChI=1S/C21H41N3O2/c1-2-3-4-5-6-7-8-9-10-11-16-23-20(25)15-13-18-24-21(26)19-14-12-17-22-19/h19,22H,2-18H2,1H3,(H,23,25)(H,24,26)/t19-/m0/s1
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US Patent
 3.69E+4n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Briefly, rPRCP was incubated in the presence or absence of various PRCP inhibitors in HEPES-carbonated buffer containing 1 mM Ala-Pro-paranitroanilin...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193276
PNG
(US9193762, RS-33-21)
Show SMILES CCCCCCCCCCCCNC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1
Show InChI InChI=1S/C22H41N3O2/c1-2-3-4-5-6-7-8-9-10-11-16-24-21(26)20-15-13-18-25(20)22(27)19-14-12-17-23-19/h19-20,23H,2-18H2,1H3,(H,24,26)/t19-,20-/m0/s1
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 4.31E+4n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Briefly, rPRCP was incubated in the presence or absence of various PRCP inhibitors in HEPES-carbonated buffer containing 1 mM Ala-Pro-paranitroanilin...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193278
PNG
(US9193762, RS-47-06)
Show SMILES CCCCCCCCCCCCNC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCN1
Show InChI InChI=1S/C21H39N3O2/c1-2-3-4-5-6-7-8-9-10-11-15-23-20(25)19-13-12-17-24(19)21(26)18-14-16-22-18/h18-19,22H,2-17H2,1H3,(H,23,25)/t18-,19-/m0/s1
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 4.37E+4n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Briefly, rPRCP was incubated in the presence or absence of various PRCP inhibitors in HEPES-carbonated buffer containing 1 mM Ala-Pro-paranitroanilin...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193279
PNG
(US9193762, RS-48-01)
Show SMILES CCCCCCCCCCCCNC(=O)C1CCN1
Show InChI InChI=1S/C16H32N2O/c1-2-3-4-5-6-7-8-9-10-11-13-18-16(19)15-12-14-17-15/h15,17H,2-14H2,1H3,(H,18,19)
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US Patent
 5.01E+4n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Human pulmonary artery endothelial cells (HPAEC) were purchased from Invitrogen (Carlsbad, Calif.) and were cultured as previously described.20 The c...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193280
PNG
(US9193762, RS-48-03)
Show SMILES CCCCCCCCCCCCNC(=O)C1CCN1C(=O)C1CCCN1
Show InChI InChI=1S/C21H39N3O2/c1-2-3-4-5-6-7-8-9-10-11-15-23-20(25)19-14-17-24(19)21(26)18-13-12-16-22-18/h18-19,22H,2-17H2,1H3,(H,23,25)
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 5.04E+4n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Human pulmonary artery endothelial cells (HPAEC) were purchased from Invitrogen (Carlsbad, Calif.) and were cultured as previously described.20 The c...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193287
PNG
(US9193762, RS-37-06)
Show SMILES CCCCCCCCCCCCNC(=O)CCCNC(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1 |r|
Show InChI InChI=1S/C29H47N3O4/c1-2-3-4-5-6-7-8-9-10-14-21-30-27(33)20-15-22-31-28(34)26-19-16-23-32(26)29(35)36-24-25-17-12-11-13-18-25/h11-13,17-18,26H,2-10,14-16,19-24H2,1H3,(H,30,33)(H,31,34)/t26-/m0/s1
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US Patent
 5.80E+4n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Human pulmonary artery endothelial cells (HPAEC) were purchased from Invitrogen (Carlsbad, Calif.) and were cultured as previously described.20 The c...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193262
PNG
(US9193762, RS-33-6)
Show SMILES CCCCCCCCCCCCCCCCNC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1
Show InChI InChI=1S/C34H55N3O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-18-25-35-32(38)30-23-19-26-36(30)33(39)31-24-20-27-37(31)34(40)41-28-29-21-16-15-17-22-29/h15-17,21-22,30-31H,2-14,18-20,23-28H2,1H3,(H,35,38)/t30-,31-/m0/s1
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 6.10E+4n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Briefly, rPRCP was incubated in the presence or absence of various PRCP inhibitors in HEPES-carbonated buffer containing 1 mM Ala-Pro-paranitroanilin...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193263
PNG
(US9193762, RS-33-7)
Show SMILES CCCCCCCCCCCCCCCNC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1
Show InChI InChI=1S/C33H53N3O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-17-24-34-31(37)29-22-18-25-35(29)32(38)30-23-19-26-36(30)33(39)40-27-28-20-15-14-16-21-28/h14-16,20-21,29-30H,2-13,17-19,22-27H2,1H3,(H,34,37)/t29-,30-/m0/s1
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 6.15E+4n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Briefly, rPRCP was incubated in the presence or absence of various PRCP inhibitors in HEPES-carbonated buffer containing 1 mM Ala-Pro-paranitroanilin...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193277
PNG
(US9193762, RS-47-01)
Show SMILES CCCCCCCCCCCCNC(=O)[C@@H]1CCCN1
Show InChI InChI=1S/C17H34N2O/c1-2-3-4-5-6-7-8-9-10-11-14-19-17(20)16-13-12-15-18-16/h16,18H,2-15H2,1H3,(H,19,20)/t16-/m0/s1
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 6.15E+4n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Briefly, rPRCP was incubated in the presence or absence of various PRCP inhibitors in HEPES-carbonated buffer containing 1 mM Ala-Pro-paranitroanilin...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193275
PNG
(US9193762, RS-33-20)
Show SMILES CCCCCCCCCCCCNC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1
Show InChI InChI=1S/C30H47N3O4/c1-2-3-4-5-6-7-8-9-10-14-21-31-28(34)26-19-15-22-32(26)29(35)27-20-16-23-33(27)30(36)37-24-25-17-12-11-13-18-25/h11-13,17-18,26-27H,2-10,14-16,19-24H2,1H3,(H,31,34)/t26-,27-/m0/s1
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 6.15E+4n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Briefly, rPRCP was incubated in the presence or absence of various PRCP inhibitors in HEPES-carbonated buffer containing 1 mM Ala-Pro-paranitroanilin...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193263
PNG
(US9193762, RS-33-7)
Show SMILES CCCCCCCCCCCCCCCNC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1
Show InChI InChI=1S/C33H53N3O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-17-24-34-31(37)29-22-18-25-35(29)32(38)30-23-19-26-36(30)33(39)40-27-28-20-15-14-16-21-28/h14-16,20-21,29-30H,2-13,17-19,22-27H2,1H3,(H,34,37)/t29-,30-/m0/s1
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 6.42E+4n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Human pulmonary artery endothelial cells (HPAEC) were purchased from Invitrogen (Carlsbad, Calif.) and were cultured as previously described.20 The c...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193275
PNG
(US9193762, RS-33-20)
Show SMILES CCCCCCCCCCCCNC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1
Show InChI InChI=1S/C30H47N3O4/c1-2-3-4-5-6-7-8-9-10-14-21-31-28(34)26-19-15-22-32(26)29(35)27-20-16-23-33(27)30(36)37-24-25-17-12-11-13-18-25/h11-13,17-18,26-27H,2-10,14-16,19-24H2,1H3,(H,31,34)/t26-,27-/m0/s1
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 6.43E+4n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Human pulmonary artery endothelial cells (HPAEC) were purchased from Invitrogen (Carlsbad, Calif.) and were cultured as previously described.20 The c...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193274
PNG
(US9193762, RS-33-19)
Show SMILES CCCCCCCNC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1
Show InChI InChI=1S/C25H37N3O4/c1-2-3-4-5-9-16-26-23(29)21-14-10-17-27(21)24(30)22-15-11-18-28(22)25(31)32-19-20-12-7-6-8-13-20/h6-8,12-13,21-22H,2-5,9-11,14-19H2,1H3,(H,26,29)/t21-,22-/m0/s1
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 8.00E+4n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Briefly, rPRCP was incubated in the presence or absence of various PRCP inhibitors in HEPES-carbonated buffer containing 1 mM Ala-Pro-paranitroanilin...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193259
PNG
(US9193762, RS-33-2)
Show SMILES Clc1ccc(CNC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)OCc2ccccc2)cc1Cl
Show InChI InChI=1S/C25H27Cl2N3O4/c26-19-11-10-18(14-20(19)27)15-28-23(31)21-8-4-12-29(21)24(32)22-9-5-13-30(22)25(33)34-16-17-6-2-1-3-7-17/h1-3,6-7,10-11,14,21-22H,4-5,8-9,12-13,15-16H2,(H,28,31)/t21-,22-/m0/s1
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 8.06E+4n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Briefly, rPRCP was incubated in the presence or absence of various PRCP inhibitors in HEPES-carbonated buffer containing 1 mM Ala-Pro-paranitroanilin...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193280
PNG
(US9193762, RS-48-03)
Show SMILES CCCCCCCCCCCCNC(=O)C1CCN1C(=O)C1CCCN1
Show InChI InChI=1S/C21H39N3O2/c1-2-3-4-5-6-7-8-9-10-11-15-23-20(25)19-14-17-24(19)21(26)18-13-12-16-22-18/h18-19,22H,2-17H2,1H3,(H,23,25)
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 8.49E+4n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Briefly, rPRCP was incubated in the presence or absence of various PRCP inhibitors in HEPES-carbonated buffer containing 1 mM Ala-Pro-paranitroanilin...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193281
PNG
(US9193762, RS-48-05)
Show SMILES CCCCCCCCCCCCNC(=O)C1CCN1C(=O)C1CCN1
Show InChI InChI=1S/C20H37N3O2/c1-2-3-4-5-6-7-8-9-10-11-14-22-19(24)18-13-16-23(18)20(25)17-12-15-21-17/h17-18,21H,2-16H2,1H3,(H,22,24)
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 1.09E+5n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Briefly, rPRCP was incubated in the presence or absence of various PRCP inhibitors in HEPES-carbonated buffer containing 1 mM Ala-Pro-paranitroanilin...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193286
PNG
(US9193762, RS-37-05)
Show SMILES Clc1ccc(CNC(=O)CCCNC(=O)[C@@H]2CCCN2C(=O)OCc2ccccc2)cc1Cl |r|
Show InChI InChI=1S/C24H27Cl2N3O4/c25-19-11-10-18(14-20(19)26)15-28-22(30)9-4-12-27-23(31)21-8-5-13-29(21)24(32)33-16-17-6-2-1-3-7-17/h1-3,6-7,10-11,14,21H,4-5,8-9,12-13,15-16H2,(H,27,31)(H,28,30)/t21-/m0/s1
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 1.11E+5n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Briefly, rPRCP was incubated in the presence or absence of various PRCP inhibitors in HEPES-carbonated buffer containing 1 mM Ala-Pro-paranitroanilin...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193272
PNG
(US9193762, RS-33-17)
Show SMILES Brc1ccc(CCNC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)OCc2ccccc2)cc1
Show InChI InChI=1S/C26H30BrN3O4/c27-21-12-10-19(11-13-21)14-15-28-24(31)22-8-4-16-29(22)25(32)23-9-5-17-30(23)26(33)34-18-20-6-2-1-3-7-20/h1-3,6-7,10-13,22-23H,4-5,8-9,14-18H2,(H,28,31)/t22-,23-/m0/s1
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 1.11E+5n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Briefly, rPRCP was incubated in the presence or absence of various PRCP inhibitors in HEPES-carbonated buffer containing 1 mM Ala-Pro-paranitroanilin...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193266
PNG
(US9193762, RS-33-11)
Show SMILES FC(F)(F)c1ccccc1CNC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1
Show InChI InChI=1S/C26H28F3N3O4/c27-26(28,29)20-11-5-4-10-19(20)16-30-23(33)21-12-6-14-31(21)24(34)22-13-7-15-32(22)25(35)36-17-18-8-2-1-3-9-18/h1-5,8-11,21-22H,6-7,12-17H2,(H,30,33)/t21-,22-/m0/s1
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 1.35E+5n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Briefly, rPRCP was incubated in the presence or absence of various PRCP inhibitors in HEPES-carbonated buffer containing 1 mM Ala-Pro-paranitroanilin...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193262
PNG
(US9193762, RS-33-6)
Show SMILES CCCCCCCCCCCCCCCCNC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1
Show InChI InChI=1S/C34H55N3O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-18-25-35-32(38)30-23-19-26-36(30)33(39)31-24-20-27-37(31)34(40)41-28-29-21-16-15-17-22-29/h15-17,21-22,30-31H,2-14,18-20,23-28H2,1H3,(H,35,38)/t30-,31-/m0/s1
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 1.41E+5n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Human pulmonary artery endothelial cells (HPAEC) were purchased from Invitrogen (Carlsbad, Calif.) and were cultured as previously described.20 The c...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193285
PNG
(US9193762, RS-37-04)
Show SMILES Clc1ccc(CNC(=O)CCCNC(=O)[C@@H]2CCCN2C(=O)OCc2ccccc2)c(Cl)c1 |r|
Show InChI InChI=1S/C24H27Cl2N3O4/c25-19-11-10-18(20(26)14-19)15-28-22(30)9-4-12-27-23(31)21-8-5-13-29(21)24(32)33-16-17-6-2-1-3-7-17/h1-3,6-7,10-11,14,21H,4-5,8-9,12-13,15-16H2,(H,27,31)(H,28,30)/t21-/m0/s1
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 1.48E+5n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Briefly, rPRCP was incubated in the presence or absence of various PRCP inhibitors in HEPES-carbonated buffer containing 1 mM Ala-Pro-paranitroanilin...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193260
PNG
(US9193762, RS-33-3)
Show SMILES Clc1ccc(CCNC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)OCc2ccccc2)cc1
Show InChI InChI=1S/C26H30ClN3O4/c27-21-12-10-19(11-13-21)14-15-28-24(31)22-8-4-16-29(22)25(32)23-9-5-17-30(23)26(33)34-18-20-6-2-1-3-7-20/h1-3,6-7,10-13,22-23H,4-5,8-9,14-18H2,(H,28,31)/t22-,23-/m0/s1
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 1.60E+5n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Briefly, rPRCP was incubated in the presence or absence of various PRCP inhibitors in HEPES-carbonated buffer containing 1 mM Ala-Pro-paranitroanilin...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193265
PNG
(US9193762, RS-33-10)
Show SMILES Clc1ccc(CNC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)OCc2ccccc2)c(Cl)c1
Show InChI InChI=1S/C25H27Cl2N3O4/c26-19-11-10-18(20(27)14-19)15-28-23(31)21-8-4-12-29(21)24(32)22-9-5-13-30(22)25(33)34-16-17-6-2-1-3-7-17/h1-3,6-7,10-11,14,21-22H,4-5,8-9,12-13,15-16H2,(H,28,31)/t21-,22-/m0/s1
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 1.93E+5n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Human pulmonary artery endothelial cells (HPAEC) were purchased from Invitrogen (Carlsbad, Calif.) and were cultured as previously described.20 The c...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193288
PNG
(US9193762, RS-37-07)
Show SMILES CCOCCOCCOCCCNC(=O)CCCNC(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1 |r|
Show InChI InChI=1S/C26H41N3O7/c1-2-33-17-18-35-20-19-34-16-8-14-27-24(30)12-6-13-28-25(31)23-11-7-15-29(23)26(32)36-21-22-9-4-3-5-10-22/h3-5,9-10,23H,2,6-8,11-21H2,1H3,(H,27,30)(H,28,31)/t23-/m0/s1
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 1.93E+5n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Human pulmonary artery endothelial cells (HPAEC) were purchased from Invitrogen (Carlsbad, Calif.) and were cultured as previously described.20 The c...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193279
PNG
(US9193762, RS-48-01)
Show SMILES CCCCCCCCCCCCNC(=O)C1CCN1
Show InChI InChI=1S/C16H32N2O/c1-2-3-4-5-6-7-8-9-10-11-13-18-16(19)15-12-14-17-15/h15,17H,2-14H2,1H3,(H,18,19)
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 1.95E+5n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Briefly, rPRCP was incubated in the presence or absence of various PRCP inhibitors in HEPES-carbonated buffer containing 1 mM Ala-Pro-paranitroanilin...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193264
PNG
(US9193762, RS-33-9)
Show SMILES Clc1ccccc1CNC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1
Show InChI InChI=1S/C25H28ClN3O4/c26-20-11-5-4-10-19(20)16-27-23(30)21-12-6-14-28(21)24(31)22-13-7-15-29(22)25(32)33-17-18-8-2-1-3-9-18/h1-5,8-11,21-22H,6-7,12-17H2,(H,27,30)/t21-,22-/m0/s1
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 2.03E+5n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Briefly, rPRCP was incubated in the presence or absence of various PRCP inhibitors in HEPES-carbonated buffer containing 1 mM Ala-Pro-paranitroanilin...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193283
PNG
(US9193762, RS-37-02)
Show SMILES Clc1cccc(CNC(=O)CCCNC(=O)[C@@H]2CCCN2C(=O)OCc2ccccc2)c1 |r|
Show InChI InChI=1S/C24H28ClN3O4/c25-20-10-4-9-19(15-20)16-27-22(29)12-5-13-26-23(30)21-11-6-14-28(21)24(31)32-17-18-7-2-1-3-8-18/h1-4,7-10,15,21H,5-6,11-14,16-17H2,(H,26,30)(H,27,29)/t21-/m0/s1
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 2.28E+5n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Briefly, rPRCP was incubated in the presence or absence of various PRCP inhibitors in HEPES-carbonated buffer containing 1 mM Ala-Pro-paranitroanilin...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193267
PNG
(US9193762, RS-33-12)
Show SMILES Clc1ccc(CNC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)OCc2ccccc2)cc1
Show InChI InChI=1S/C25H28ClN3O4/c26-20-12-10-18(11-13-20)16-27-23(30)21-8-4-14-28(21)24(31)22-9-5-15-29(22)25(32)33-17-19-6-2-1-3-7-19/h1-3,6-7,10-13,21-22H,4-5,8-9,14-17H2,(H,27,30)/t21-,22-/m0/s1
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 2.57E+5n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Human pulmonary artery endothelial cells (HPAEC) were purchased from Invitrogen (Carlsbad, Calif.) and were cultured as previously described.20 The c...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193284
PNG
(US9193762, RS-37-03)
Show SMILES Clc1ccc(CNC(=O)CCCNC(=O)[C@@H]2CCCN2C(=O)OCc2ccccc2)cc1 |r|
Show InChI InChI=1S/C24H28ClN3O4/c25-20-12-10-18(11-13-20)16-27-22(29)9-4-14-26-23(30)21-8-5-15-28(21)24(31)32-17-19-6-2-1-3-7-19/h1-3,6-7,10-13,21H,4-5,8-9,14-17H2,(H,26,30)(H,27,29)/t21-/m0/s1
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 2.59E+5n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Briefly, rPRCP was incubated in the presence or absence of various PRCP inhibitors in HEPES-carbonated buffer containing 1 mM Ala-Pro-paranitroanilin...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193267
PNG
(US9193762, RS-33-12)
Show SMILES Clc1ccc(CNC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)OCc2ccccc2)cc1
Show InChI InChI=1S/C25H28ClN3O4/c26-20-12-10-18(11-13-20)16-27-23(30)21-8-4-14-28(21)24(31)22-9-5-15-29(22)25(32)33-17-19-6-2-1-3-7-19/h1-3,6-7,10-13,21-22H,4-5,8-9,14-17H2,(H,27,30)/t21-,22-/m0/s1
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 2.65E+5n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Briefly, rPRCP was incubated in the presence or absence of various PRCP inhibitors in HEPES-carbonated buffer containing 1 mM Ala-Pro-paranitroanilin...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193272
PNG
(US9193762, RS-33-17)
Show SMILES Brc1ccc(CCNC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)OCc2ccccc2)cc1
Show InChI InChI=1S/C26H30BrN3O4/c27-21-12-10-19(11-13-21)14-15-28-24(31)22-8-4-16-29(22)25(32)23-9-5-17-30(23)26(33)34-18-20-6-2-1-3-7-20/h1-3,6-7,10-13,22-23H,4-5,8-9,14-18H2,(H,28,31)/t22-,23-/m0/s1
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 2.83E+5n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Human pulmonary artery endothelial cells (HPAEC) were purchased from Invitrogen (Carlsbad, Calif.) and were cultured as previously described.20 The c...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193273
PNG
(US9193762, RS-33-18)
Show SMILES CCCCCNC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1
Show InChI InChI=1S/C23H33N3O4/c1-2-3-7-14-24-21(27)19-12-8-15-25(19)22(28)20-13-9-16-26(20)23(29)30-17-18-10-5-4-6-11-18/h4-6,10-11,19-20H,2-3,7-9,12-17H2,1H3,(H,24,27)/t19-,20-/m0/s1
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 2.89E+5n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Briefly, rPRCP was incubated in the presence or absence of various PRCP inhibitors in HEPES-carbonated buffer containing 1 mM Ala-Pro-paranitroanilin...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193270
PNG
(US9193762, RS-33-15)
Show SMILES COc1ccccc1CNC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1
Show InChI InChI=1S/C26H31N3O5/c1-33-23-14-6-5-11-20(23)17-27-24(30)21-12-7-15-28(21)25(31)22-13-8-16-29(22)26(32)34-18-19-9-3-2-4-10-19/h2-6,9-11,14,21-22H,7-8,12-13,15-18H2,1H3,(H,27,30)/t21-,22-/m0/s1
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 2.89E+5n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Briefly, rPRCP was incubated in the presence or absence of various PRCP inhibitors in HEPES-carbonated buffer containing 1 mM Ala-Pro-paranitroanilin...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193282
PNG
(US9193762, RS-37-01)
Show SMILES Clc1ccccc1CNC(=O)CCCNC(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1 |r|
Show InChI InChI=1S/C24H28ClN3O4/c25-20-11-5-4-10-19(20)16-27-22(29)13-6-14-26-23(30)21-12-7-15-28(21)24(31)32-17-18-8-2-1-3-9-18/h1-5,8-11,21H,6-7,12-17H2,(H,26,30)(H,27,29)/t21-/m0/s1
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 3.32E+5n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Briefly, rPRCP was incubated in the presence or absence of various PRCP inhibitors in HEPES-carbonated buffer containing 1 mM Ala-Pro-paranitroanilin...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193258
PNG
(US9193762, RS-33-1)
Show SMILES O=C(NCc1ccccc1)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1
Show InChI InChI=1S/C25H29N3O4/c29-23(26-17-19-9-3-1-4-10-19)21-13-7-15-27(21)24(30)22-14-8-16-28(22)25(31)32-18-20-11-5-2-6-12-20/h1-6,9-12,21-22H,7-8,13-18H2,(H,26,29)/t21-,22-/m0/s1
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 3.38E+5n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Briefly, rPRCP was incubated in the presence or absence of various PRCP inhibitors in HEPES-carbonated buffer containing 1 mM Ala-Pro-paranitroanilin...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193288
PNG
(US9193762, RS-37-07)
Show SMILES CCOCCOCCOCCCNC(=O)CCCNC(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1 |r|
Show InChI InChI=1S/C26H41N3O7/c1-2-33-17-18-35-20-19-34-16-8-14-27-24(30)12-6-13-28-25(31)23-11-7-15-29(23)26(32)36-21-22-9-4-3-5-10-22/h3-5,9-10,23H,2,6-8,11-21H2,1H3,(H,27,30)(H,28,31)/t23-/m0/s1
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 3.51E+5n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Briefly, rPRCP was incubated in the presence or absence of various PRCP inhibitors in HEPES-carbonated buffer containing 1 mM Ala-Pro-paranitroanilin...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193271
PNG
(US9193762, RS-33-16)
Show SMILES COc1cccc(CNC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)OCc2ccccc2)c1
Show InChI InChI=1S/C26H31N3O5/c1-33-21-11-5-10-20(16-21)17-27-24(30)22-12-6-14-28(22)25(31)23-13-7-15-29(23)26(32)34-18-19-8-3-2-4-9-19/h2-5,8-11,16,22-23H,6-7,12-15,17-18H2,1H3,(H,27,30)/t22-,23-/m0/s1
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 3.94E+5n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Briefly, rPRCP was incubated in the presence or absence of various PRCP inhibitors in HEPES-carbonated buffer containing 1 mM Ala-Pro-paranitroanilin...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193261
PNG
(US9193762, RS-33-4)
Show SMILES COc1ccccc1CCNC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1
Show InChI InChI=1S/C27H33N3O5/c1-34-24-14-6-5-11-21(24)15-16-28-25(31)22-12-7-17-29(22)26(32)23-13-8-18-30(23)27(33)35-19-20-9-3-2-4-10-20/h2-6,9-11,14,22-23H,7-8,12-13,15-19H2,1H3,(H,28,31)/t22-,23-/m0/s1
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 4.25E+5n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Briefly, rPRCP was incubated in the presence or absence of various PRCP inhibitors in HEPES-carbonated buffer containing 1 mM Ala-Pro-paranitroanilin...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193274
PNG
(US9193762, RS-33-19)
Show SMILES CCCCCCCNC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1
Show InChI InChI=1S/C25H37N3O4/c1-2-3-4-5-9-16-26-23(29)21-14-10-17-27(21)24(30)22-15-11-18-28(22)25(31)32-19-20-12-7-6-8-13-20/h6-8,12-13,21-22H,2-5,9-11,14-19H2,1H3,(H,26,29)/t21-,22-/m0/s1
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 4.37E+5n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Human pulmonary artery endothelial cells (HPAEC) were purchased from Invitrogen (Carlsbad, Calif.) and were cultured as previously described.20 The c...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193271
PNG
(US9193762, RS-33-16)
Show SMILES COc1cccc(CNC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)OCc2ccccc2)c1
Show InChI InChI=1S/C26H31N3O5/c1-33-21-11-5-10-20(16-21)17-27-24(30)22-12-6-14-28(22)25(31)23-13-7-15-29(23)26(32)34-18-19-8-3-2-4-9-19/h2-5,8-11,16,22-23H,6-7,12-15,17-18H2,1H3,(H,27,30)/t22-,23-/m0/s1
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 4.50E+5n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Human pulmonary artery endothelial cells (HPAEC) were purchased from Invitrogen (Carlsbad, Calif.) and were cultured as previously described.20 The c...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193286
PNG
(US9193762, RS-37-05)
Show SMILES Clc1ccc(CNC(=O)CCCNC(=O)[C@@H]2CCCN2C(=O)OCc2ccccc2)cc1Cl |r|
Show InChI InChI=1S/C24H27Cl2N3O4/c25-19-11-10-18(14-20(19)26)15-28-22(30)9-4-12-27-23(31)21-8-5-13-29(21)24(32)33-16-17-6-2-1-3-7-17/h1-3,6-7,10-11,14,21H,4-5,8-9,12-13,15-16H2,(H,27,31)(H,28,30)/t21-/m0/s1
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 4.56E+5n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Human pulmonary artery endothelial cells (HPAEC) were purchased from Invitrogen (Carlsbad, Calif.) and were cultured as previously described.20 The c...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193269
PNG
(US9193762, RS-33-14)
Show SMILES Clc1cccc(CNC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)OCc2ccccc2)c1
Show InChI InChI=1S/C25H28ClN3O4/c26-20-10-4-9-19(15-20)16-27-23(30)21-11-5-13-28(21)24(31)22-12-6-14-29(22)25(32)33-17-18-7-2-1-3-8-18/h1-4,7-10,15,21-22H,5-6,11-14,16-17H2,(H,27,30)/t21-,22-/m0/s1
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 4.68E+5n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Briefly, rPRCP was incubated in the presence or absence of various PRCP inhibitors in HEPES-carbonated buffer containing 1 mM Ala-Pro-paranitroanilin...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193277
PNG
(US9193762, RS-47-01)
Show SMILES CCCCCCCCCCCCNC(=O)[C@@H]1CCCN1
Show InChI InChI=1S/C17H34N2O/c1-2-3-4-5-6-7-8-9-10-11-14-19-17(20)16-13-12-15-18-16/h16,18H,2-15H2,1H3,(H,19,20)/t16-/m0/s1
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 4.77E+5n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Human pulmonary artery endothelial cells (HPAEC) were purchased from Invitrogen (Carlsbad, Calif.) and were cultured as previously described.20 The c...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193266
PNG
(US9193762, RS-33-11)
Show SMILES FC(F)(F)c1ccccc1CNC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1
Show InChI InChI=1S/C26H28F3N3O4/c27-26(28,29)20-11-5-4-10-19(20)16-30-23(33)21-12-6-14-31(21)24(34)22-13-7-15-32(22)25(35)36-17-18-8-2-1-3-9-18/h1-5,8-11,21-22H,6-7,12-17H2,(H,30,33)/t21-,22-/m0/s1
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 4.89E+5n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Human pulmonary artery endothelial cells (HPAEC) were purchased from Invitrogen (Carlsbad, Calif.) and were cultured as previously described.20 The c...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193268
PNG
(US9193762, RS-33-13)
Show SMILES Fc1cccc(F)c1CNC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1
Show InChI InChI=1S/C25H27F2N3O4/c26-19-9-4-10-20(27)18(19)15-28-23(31)21-11-5-13-29(21)24(32)22-12-6-14-30(22)25(33)34-16-17-7-2-1-3-8-17/h1-4,7-10,21-22H,5-6,11-16H2,(H,28,31)/t21-,22-/m0/s1
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 5.42E+5n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Briefly, rPRCP was incubated in the presence or absence of various PRCP inhibitors in HEPES-carbonated buffer containing 1 mM Ala-Pro-paranitroanilin...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193283
PNG
(US9193762, RS-37-02)
Show SMILES Clc1cccc(CNC(=O)CCCNC(=O)[C@@H]2CCCN2C(=O)OCc2ccccc2)c1 |r|
Show InChI InChI=1S/C24H28ClN3O4/c25-20-10-4-9-19(15-20)16-27-22(29)12-5-13-26-23(30)21-11-6-14-28(21)24(31)32-17-18-7-2-1-3-8-18/h1-4,7-10,15,21H,5-6,11-14,16-17H2,(H,26,30)(H,27,29)/t21-/m0/s1
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 5.66E+5n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Human pulmonary artery endothelial cells (HPAEC) were purchased from Invitrogen (Carlsbad, Calif.) and were cultured as previously described.20 The c...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193273
PNG
(US9193762, RS-33-18)
Show SMILES CCCCCNC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1
Show InChI InChI=1S/C23H33N3O4/c1-2-3-7-14-24-21(27)19-12-8-15-25(19)22(28)20-13-9-16-26(20)23(29)30-17-18-10-5-4-6-11-18/h4-6,10-11,19-20H,2-3,7-9,12-17H2,1H3,(H,24,27)/t19-,20-/m0/s1
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 5.66E+5n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Human pulmonary artery endothelial cells (HPAEC) were purchased from Invitrogen (Carlsbad, Calif.) and were cultured as previously described.20 The c...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193285
PNG
(US9193762, RS-37-04)
Show SMILES Clc1ccc(CNC(=O)CCCNC(=O)[C@@H]2CCCN2C(=O)OCc2ccccc2)c(Cl)c1 |r|
Show InChI InChI=1S/C24H27Cl2N3O4/c25-19-11-10-18(20(26)14-19)15-28-22(30)9-4-12-27-23(31)21-8-5-13-29(21)24(32)33-16-17-6-2-1-3-7-17/h1-3,6-7,10-11,14,21H,4-5,8-9,12-13,15-16H2,(H,27,31)(H,28,30)/t21-/m0/s1
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 6.04E+5n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Human pulmonary artery endothelial cells (HPAEC) were purchased from Invitrogen (Carlsbad, Calif.) and were cultured as previously described.20 The c...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193284
PNG
(US9193762, RS-37-03)
Show SMILES Clc1ccc(CNC(=O)CCCNC(=O)[C@@H]2CCCN2C(=O)OCc2ccccc2)cc1 |r|
Show InChI InChI=1S/C24H28ClN3O4/c25-20-12-10-18(11-13-20)16-27-22(29)9-4-14-26-23(30)21-8-5-15-28(21)24(31)32-17-19-6-2-1-3-7-19/h1-3,6-7,10-13,21H,4-5,8-9,14-17H2,(H,26,30)(H,27,29)/t21-/m0/s1
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 6.69E+5n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Human pulmonary artery endothelial cells (HPAEC) were purchased from Invitrogen (Carlsbad, Calif.) and were cultured as previously described.20 The c...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193282
PNG
(US9193762, RS-37-01)
Show SMILES Clc1ccccc1CNC(=O)CCCNC(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1 |r|
Show InChI InChI=1S/C24H28ClN3O4/c25-20-11-5-4-10-19(20)16-27-22(29)13-6-14-26-23(30)21-12-7-15-28(21)24(31)32-17-18-8-2-1-3-9-18/h1-5,8-11,21H,6-7,12-17H2,(H,26,30)(H,27,29)/t21-/m0/s1
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 6.94E+5n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Human pulmonary artery endothelial cells (HPAEC) were purchased from Invitrogen (Carlsbad, Calif.) and were cultured as previously described.20 The c...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193270
PNG
(US9193762, RS-33-15)
Show SMILES COc1ccccc1CNC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1
Show InChI InChI=1S/C26H31N3O5/c1-33-23-14-6-5-11-20(23)17-27-24(30)21-12-7-15-28(21)25(31)22-13-8-16-29(22)26(32)34-18-19-9-3-2-4-10-19/h2-6,9-11,14,21-22H,7-8,12-13,15-18H2,1H3,(H,27,30)/t21-,22-/m0/s1
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 7.71E+5n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Human pulmonary artery endothelial cells (HPAEC) were purchased from Invitrogen (Carlsbad, Calif.) and were cultured as previously described.20 The c...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193268
PNG
(US9193762, RS-33-13)
Show SMILES Fc1cccc(F)c1CNC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1
Show InChI InChI=1S/C25H27F2N3O4/c26-19-9-4-10-20(27)18(19)15-28-23(31)21-11-5-13-29(21)24(32)22-12-6-14-30(22)25(33)34-16-17-7-2-1-3-8-17/h1-4,7-10,21-22H,5-6,11-16H2,(H,28,31)/t21-,22-/m0/s1
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 8.36E+5n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Human pulmonary artery endothelial cells (HPAEC) were purchased from Invitrogen (Carlsbad, Calif.) and were cultured as previously described.20 The c...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
Lysosomal Pro-X carboxypeptidase


(Homo sapiens (Human))		BDBM193269
PNG
(US9193762, RS-33-14)
Show SMILES Clc1cccc(CNC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)OCc2ccccc2)c1
Show InChI InChI=1S/C25H28ClN3O4/c26-20-10-4-9-19(15-20)16-27-23(30)21-11-5-13-28(21)24(31)22-12-6-14-29(22)25(32)33-17-18-7-2-1-3-8-18/h1-4,7-10,15,21-22H,5-6,11-14,16-17H2,(H,27,30)/t21-,22-/m0/s1
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US Patent
 9.00E+5n/an/an/an/an/an/an/an/a



UNIVERSITY OF MISSISSIPPI

US Patent


Assay Description
Human pulmonary artery endothelial cells (HPAEC) were purchased from Invitrogen (Carlsbad, Calif.) and were cultured as previously described.20 The c...

US Patent US9193762 (2015)


BindingDB Entry DOI: 10.7270/Q2ST7NN2
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%